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Items: 1 to 50 of 70

1.

TRPC Channels in the SOCE Scenario.

Lopez JJ, Jardin I, Sanchez-Collado J, Salido GM, Smani T, Rosado JA.

Cells. 2020 Jan 5;9(1). pii: E126. doi: 10.3390/cells9010126. Review.

2.

Adenylyl Cyclase Type 8 Overexpression Impairs Phosphorylation-Dependent Orai1 Inactivation and Promotes Migration in MDA-MB-231 Breast Cancer Cells.

Sanchez-Collado J, Lopez JJ, Jardin I, Camello PJ, Falcon D, Regodon S, Salido GM, Smani T, Rosado JA.

Cancers (Basel). 2019 Oct 23;11(11). pii: E1624. doi: 10.3390/cancers11111624.

3.

Molecular Basis and Regulation of Store-Operated Calcium Entry.

Lopez JJ, Jardin I, Albarrán L, Sanchez-Collado J, Cantonero C, Salido GM, Smani T, Rosado JA.

Adv Exp Med Biol. 2020;1131:445-469. doi: 10.1007/978-3-030-12457-1_17. Review.

PMID:
31646520
4.

STIM1 phosphorylation at Y316 modulates its interaction with SARAF and the activation of SOCE and I CRAC.

Lopez E, Frischauf I, Jardin I, Derler I, Muik M, Cantonero C, Salido GM, Smani T, Rosado JA, Redondo PC.

J Cell Sci. 2019 May 15;132(10). pii: jcs226019. doi: 10.1242/jcs.226019.

5.

Store-independent Orai1-mediated Ca2+ entry and cancer.

Cantonero C, Sanchez-Collado J, Gonzalez-Nuñez MA, Salido GM, Lopez JJ, Jardin I, Rosado JA.

Cell Calcium. 2019 Jun;80:1-7. doi: 10.1016/j.ceca.2019.02.012. Epub 2019 Mar 7. Review.

PMID:
30921687
6.

Store-Operated Ca2+ Entry in Breast Cancer Cells: Remodeling and Functional Role.

Jardin I, Lopez JJ, Salido GM, Rosado JA.

Int J Mol Sci. 2018 Dec 14;19(12). pii: E4053. doi: 10.3390/ijms19124053. Review.

7.

EFHB is a Novel Cytosolic Ca2+ Sensor That Modulates STIM1-SARAF Interaction.

Albarran L, Lopez JJ, Jardin I, Sanchez-Collado J, Berna-Erro A, Smani T, Camello PJ, Salido GM, Rosado JA.

Cell Physiol Biochem. 2018;51(3):1164-1178. doi: 10.1159/000495494. Epub 2018 Nov 27.

8.

Filamin A modulates platelet function.

Lopez JJ, Jardin I, Rosado JA.

Aging (Albany NY). 2018 Nov 6;10(11):3052-3053. doi: 10.18632/aging.101635. No abstract available.

9.

(-)‑Oleocanthal inhibits proliferation and migration by modulating Ca2+ entry through TRPC6 in breast cancer cells.

Diez-Bello R, Jardin I, Lopez JJ, El Haouari M, Ortega-Vidal J, Altarejos J, Salido GM, Salido S, Rosado JA.

Biochim Biophys Acta Mol Cell Res. 2019 Mar;1866(3):474-485. doi: 10.1016/j.bbamcr.2018.10.010. Epub 2018 Oct 12.

PMID:
30321616
10.

[How I do? a treatment with fractional CO2 LASER for vulvovaginal atrophy symptoms in menopausal women].

Jardin I, Louis-Vahdat C, Canlorbe G, Mergui JL, Uzan C, Azaïs H.

Gynecol Obstet Fertil Senol. 2018 Nov;46(10-11):735-739. doi: 10.1016/j.gofs.2018.09.002. Epub 2018 Sep 25. French. No abstract available.

PMID:
30266539
11.

[CO2 LASER for the treatment of vaginal symptoms of genitourinary syndrome of menopause].

Jardin I, Canlorbe G, Mergui JL, Nikpayam M, Belghiti J, Uzan C, Azaïs H.

Gynecol Obstet Fertil Senol. 2018 Nov;46(10-11):729-734. doi: 10.1016/j.gofs.2018.09.001. Epub 2018 Sep 18. French.

PMID:
30241737
12.

TRPC6 Channels Are Required for Proliferation, Migration and Invasion of Breast Cancer Cell Lines by Modulation of Orai1 and Orai3 Surface Exposure.

Jardin I, Diez-Bello R, Lopez JJ, Redondo PC, Salido GM, Smani T, Rosado JA.

Cancers (Basel). 2018 Sep 14;10(9). pii: E331. doi: 10.3390/cancers10090331.

13.

Flavonoids and Platelet-Derived Thrombotic Disorders.

Lopez JJ, El Haouari M, Jardin I, Alonso N, Regodon S, Diez-Bello R, Redondo PC, Rosado JA.

Curr Med Chem. 2019;26(39):7035-7047. doi: 10.2174/0929867325666180417170218.

PMID:
29667548
14.

Filamin A Modulates Store-Operated Ca2+ Entry by Regulating STIM1 (Stromal Interaction Molecule 1)-Orai1 Association in Human Platelets.

Lopez JJ, Albarrán L, Jardín I, Sanchez-Collado J, Redondo PC, Bermejo N, Bobe R, Smani T, Rosado JA.

Arterioscler Thromb Vasc Biol. 2018 Feb;38(2):386-397. doi: 10.1161/ATVBAHA.117.310139. Epub 2017 Dec 28.

PMID:
29284605
15.

Fine-tuning of store-operated calcium entry by fast and slow Ca2+-dependent inactivation: Involvement of SARAF.

Jardín I, Albarran L, Salido GM, López JJ, Sage SO, Rosado JA.

Biochim Biophys Acta Mol Cell Res. 2018 Mar;1865(3):463-469. doi: 10.1016/j.bbamcr.2017.12.001. Epub 2017 Dec 6. Review.

16.

Fine-tuning of microRNAs in Type 2 Diabetes Mellitus.

Rosado JA, Diez-Bello R, Salido GM, Jardin I.

Curr Med Chem. 2019;26(22):4102-4118. doi: 10.2174/0929867325666171205163944. Review.

PMID:
29210640
17.

Involvement of stanniocalcins in the deregulation of glycaemia in obese mice and type 2 diabetic patients.

López JJ, Jardín I, Cantonero Chamorro C, Duran ML, Tarancón Rubio MJ, Reyes Panadero M, Jiménez F, Montero R, González MJ, Martínez M, Hernández MJ, Brull JM, Corbacho AJ, Delgado E, Granados MP, Gómez-Gordo L, Rosado JA, Redondo PC.

J Cell Mol Med. 2018 Jan;22(1):684-694. doi: 10.1111/jcmm.13355. Epub 2017 Oct 9.

18.

TRPs in Pain Sensation.

Jardín I, López JJ, Diez R, Sánchez-Collado J, Cantonero C, Albarrán L, Woodard GE, Redondo PC, Salido GM, Smani T, Rosado JA.

Front Physiol. 2017 Jun 9;8:392. doi: 10.3389/fphys.2017.00392. eCollection 2017. Review.

19.

Role of STIM2 in cell function and physiopathology.

Berna-Erro A, Jardin I, Salido GM, Rosado JA.

J Physiol. 2017 May 15;595(10):3111-3128. doi: 10.1113/JP273889. Epub 2017 Feb 19. Review.

20.

Orai1 and Orai2 mediate store-operated calcium entry that regulates HL60 cell migration and FAK phosphorylation.

Diez-Bello R, Jardin I, Salido GM, Rosado JA.

Biochim Biophys Acta Mol Cell Res. 2017 Jun;1864(6):1064-1070. doi: 10.1016/j.bbamcr.2016.11.014. Epub 2016 Nov 16.

21.

Regulation of Platelet Function by Orai, STIM and TRP.

Berna-Erro A, Jardín I, Smani T, Rosado JA.

Adv Exp Med Biol. 2016;898:157-81. doi: 10.1007/978-3-319-26974-0_8. Review.

PMID:
27161229
22.

The STIM1: Orai Interaction.

Frischauf I, Fahrner M, Jardín I, Romanin C.

Adv Exp Med Biol. 2016;898:25-46. doi: 10.1007/978-3-319-26974-0_2. Review.

PMID:
27161223
23.

Molecular mechanisms of STIM/Orai communication.

Derler I, Jardin I, Romanin C.

Am J Physiol Cell Physiol. 2016 Apr 15;310(8):C643-62. doi: 10.1152/ajpcell.00007.2016. Epub 2016 Jan 28. Review.

24.

Cholesterol modulates Orai1 channel function.

Derler I, Jardin I, Stathopulos PB, Muik M, Fahrner M, Zayats V, Pandey SK, Poteser M, Lackner B, Absolonova M, Schindl R, Groschner K, Ettrich R, Ikura M, Romanin C.

Sci Signal. 2016 Jan 26;9(412):ra10. doi: 10.1126/scisignal.aad7808.

25.

STIM and Orai1 Variants in Store-Operated Calcium Entry.

Rosado JA, Diez R, Smani T, Jardín I.

Front Pharmacol. 2016 Jan 13;6:325. doi: 10.3389/fphar.2015.00325. eCollection 2015. Review.

26.

A calcium-accumulating region, CAR, in the channel Orai1 enhances Ca(2+) permeation and SOCE-induced gene transcription.

Frischauf I, Zayats V, Deix M, Hochreiter A, Jardin I, Muik M, Lackner B, Svobodová B, Pammer T, Litviňuková M, Sridhar AA, Derler I, Bogeski I, Romanin C, Ettrich RH, Schindl R.

Sci Signal. 2015 Dec 22;8(408):ra131. doi: 10.1126/scisignal.aab1901.

27.

Apelin: an antithrombotic factor that inhibits platelet function.

Adam F, Khatib AM, Lopez JJ, Vatier C, Turpin S, Muscat A, Soulet F, Aries A, Jardin I, Bobe R, Stepanian A, de Prost D, Dray C, Rosado JA, Valet P, Feve B, Siegfried G.

Blood. 2016 Feb 18;127(7):908-20. doi: 10.1182/blood-2014-05-578781. Epub 2015 Dec 3.

PMID:
26634301
28.

STIM and calcium channel complexes in cancer.

Jardin I, Rosado JA.

Biochim Biophys Acta. 2016 Jun;1863(6 Pt B):1418-26. doi: 10.1016/j.bbamcr.2015.10.003. Epub 2015 Oct 9. Review.

29.

Regulators of G-protein-signaling proteins: negative modulators of G-protein-coupled receptor signaling.

Woodard GE, Jardín I, Berna-Erro A, Salido GM, Rosado JA.

Int Rev Cell Mol Biol. 2015;317:97-183. doi: 10.1016/bs.ircmb.2015.02.001. Epub 2015 Mar 5. Review.

PMID:
26008785
30.

A coiled-coil clamp controls both conformation and clustering of stromal interaction molecule 1 (STIM1).

Fahrner M, Muik M, Schindl R, Butorac C, Stathopulos P, Zheng L, Jardin I, Ikura M, Romanin C.

J Biol Chem. 2014 Nov 28;289(48):33231-44. doi: 10.1074/jbc.M114.610022. Epub 2014 Oct 23.

31.

Complex role of STIM1 in the activation of store-independent Orai1/3 channels.

Zhang X, Zhang W, González-Cobos JC, Jardin I, Romanin C, Matrougui K, Trebak M.

J Gen Physiol. 2014 Mar;143(3):345-59. doi: 10.1085/jgp.201311084.

32.

The STIM1/Orai signaling machinery.

Fahrner M, Derler I, Jardin I, Romanin C.

Channels (Austin). 2013 Sep-Oct;7(5):330-43. doi: 10.4161/chan.26742. Epub 2013 Oct 9. Review.

33.

The extended transmembrane Orai1 N-terminal (ETON) region combines binding interface and gate for Orai1 activation by STIM1.

Derler I, Plenk P, Fahrner M, Muik M, Jardin I, Schindl R, Gruber HJ, Groschner K, Romanin C.

J Biol Chem. 2013 Oct 4;288(40):29025-34. doi: 10.1074/jbc.M113.501510. Epub 2013 Aug 13.

34.

Pharmacology of TRP channels in the vasculature.

Jardín I, Dionisio N, Lopez JJ, Salido GM, Rosado JA.

Curr Vasc Pharmacol. 2013 Jul;11(4):480-9. Review.

PMID:
23905642
35.

Homer proteins in Ca²⁺ entry.

Jardin I, López JJ, Berna-Erro A, Salido GM, Rosado JA.

IUBMB Life. 2013 Jun;65(6):497-504. doi: 10.1002/iub.1162. Epub 2013 Apr 3. Review.

36.

The TRPV1 ion channel is expressed in human but not mouse platelets.

Sage SO, Jarvis GE, Jardín I, Rosado JA, Harper AG.

Platelets. 2014;25(5):390-2. doi: 10.3109/09537104.2013.777952. Epub 2013 Mar 15. No abstract available.

PMID:
23495929
37.

The polybasic lysine-rich domain of plasma membrane-resident STIM1 is essential for the modulation of store-operated divalent cation entry by extracellular calcium.

Jardin I, Dionisio N, Frischauf I, Berna-Erro A, Woodard GE, López JJ, Salido GM, Rosado JA.

Cell Signal. 2013 May;25(5):1328-37. doi: 10.1016/j.cellsig.2013.01.025. Epub 2013 Feb 8.

PMID:
23395841
38.

Canonical transient receptor potential (TRPC) 1 acts as a negative regulator for vanilloid TRPV6-mediated Ca2+ influx.

Schindl R, Fritsch R, Jardin I, Frischauf I, Kahr H, Muik M, Riedl MC, Groschner K, Romanin C.

J Biol Chem. 2012 Oct 12;287(42):35612-20. doi: 10.1074/jbc.M112.400952. Epub 2012 Aug 29.

39.

Transient receptor potential channels in human platelets: expression and functional role.

Dionisio N, Redondo PC, Jardin I, Rosado JA.

Curr Mol Med. 2012 Dec;12(10):1319-28. Review.

PMID:
22834833
40.

Vaccination prepartum enhances the beneficial effects of melatonin on the immune response and reduces platelet responsiveness in sheep.

Regodón S, Ramos A, Míguez MP, Carrillo-Vico A, Rosado JA, Jardín I.

BMC Vet Res. 2012 Jun 20;8:84. doi: 10.1186/1746-6148-8-84.

41.

Identification and function of exchange proteins activated directly by cyclic AMP (Epac) in mammalian spermatozoa.

Miro-Moran A, Jardin I, Ortega-Ferrusola C, Salido GM, Peña FJ, Tapia JA, Aparicio IM.

PLoS One. 2012;7(5):e37713. doi: 10.1371/journal.pone.0037713. Epub 2012 May 25.

42.

Homers regulate calcium entry and aggregation in human platelets: a role for Homers in the association between STIM1 and Orai1.

Jardin I, Albarrán L, Bermejo N, Salido GM, Rosado JA.

Biochem J. 2012 Jul 1;445(1):29-38. doi: 10.1042/BJ20120471.

PMID:
22506990
43.

STIM1 tyrosine-phosphorylation is required for STIM1-Orai1 association in human platelets.

Lopez E, Jardin I, Berna-Erro A, Bermejo N, Salido GM, Sage SO, Rosado JA, Redondo PC.

Cell Signal. 2012 Jun;24(6):1315-22. doi: 10.1016/j.cellsig.2012.02.012. Epub 2012 Feb 25.

PMID:
22387225
44.

Ca2+ leakage rate from agonist-sensitive intracellular pools is altered in platelets from patients with type 2 diabetes.

Zbidi H, Jardin I, Bartegi A, Salido GM, Rosado JA.

Platelets. 2011;22(4):284-93. doi: 10.3109/09537104.2010.528813. Epub 2011 Apr 28.

PMID:
21526890
45.

STIM1 and STIM2 are located in the acidic Ca2+ stores and associates with Orai1 upon depletion of the acidic stores in human platelets.

Zbidi H, Jardin I, Woodard GE, Lopez JJ, Berna-Erro A, Salido GM, Rosado JA.

J Biol Chem. 2011 Apr 8;286(14):12257-70. doi: 10.1074/jbc.M110.190694. Epub 2011 Feb 14.

46.

Attenuated store-operated divalent cation entry and association between STIM1, Orai1, hTRPC1 and hTRPC6 in platelets from type 2 diabetic patients.

Jardín I, López JJ, Zbidi H, Bartegi A, Salido GM, Rosado JA.

Blood Cells Mol Dis. 2011 Mar 15;46(3):252-60. doi: 10.1016/j.bcmd.2010.12.008.

PMID:
21303733
47.

The TRPC ion channels: association with Orai1 and STIM1 proteins and participation in capacitative and non-capacitative calcium entry.

Salido GM, Jardín I, Rosado JA.

Adv Exp Med Biol. 2011;704:413-33. doi: 10.1007/978-94-007-0265-3_23. Review.

PMID:
21290309
48.

Lipid rafts are essential for the regulation of SOCE by plasma membrane resident STIM1 in human platelets.

Dionisio N, Galán C, Jardín I, Salido GM, Rosado JA.

Biochim Biophys Acta. 2011 Mar;1813(3):431-7. doi: 10.1016/j.bbamcr.2011.01.010. Epub 2011 Jan 19.

49.

Role of oxidant scavengers in the prevention of Ca²+ homeostasis disorders.

Galan C, Jardín I, Dionisio N, Salido G, Rosado JA.

Molecules. 2010 Oct 15;15(10):7167-87. doi: 10.3390/molecules15107167. Review.

50.

Homocysteine, intracellular signaling and thrombotic disorders.

Dionisio N, Jardín I, Salido GM, Rosado JA.

Curr Med Chem. 2010;17(27):3109-19. Review.

PMID:
20629621

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