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Items: 1 to 50 of 56

1.

Pharmacological characterization of the seven human NOX isoforms and their inhibitors.

Augsburger F, Filippova A, Rasti D, Seredenina T, Lam M, Maghzal G, Mahiout Z, Jansen-Dürr P, Knaus UG, Doroshow J, Stocker R, Krause KH, Jaquet V.

Redox Biol. 2019 Jul 11;26:101272. doi: 10.1016/j.redox.2019.101272. [Epub ahead of print]

2.

Tubular NOX4 expression decreases in chronic kidney disease but does not modify fibrosis evolution.

Rajaram RD, Dissard R, Faivre A, Ino F, Delitsikou V, Jaquet V, Cagarelli T, Lindenmeyer M, Jansen-Duerr P, Cohen C, Moll S, de Seigneux S.

Redox Biol. 2019 Jun 5;26:101234. doi: 10.1016/j.redox.2019.101234. [Epub ahead of print]

3.

Methods for Detection of NOX-Derived Superoxide Radical Anion and Hydrogen Peroxide in Cells.

Augsburger F, Filippova A, Jaquet V.

Methods Mol Biol. 2019;1982:233-241. doi: 10.1007/978-1-4939-9424-3_13.

PMID:
31172475
4.

NOX5 Cell-Free Assay for the High-Throughput Screening of Small Molecules.

Augsburger F, Rasti D, Cambet Y, Jaquet V.

Methods Mol Biol. 2019;1982:103-111. doi: 10.1007/978-1-4939-9424-3_6.

PMID:
31172468
5.

Mammalian NADPH Oxidases.

Buvelot H, Jaquet V, Krause KH.

Methods Mol Biol. 2019;1982:17-36. doi: 10.1007/978-1-4939-9424-3_2.

PMID:
31172464
6.

Navigating in vitro bioactivity data by investigating available resources using model compounds.

Ilmjärv S, Augsburger F, Bolleman JT, Liechti R, Bridge AJ, Sandström J, Jaquet V, Xenarios I, Krause KH.

Sci Data. 2019 Apr 29;6(1):45. doi: 10.1038/s41597-019-0046-1. No abstract available.

7.

Contribution of RNA Degradation to Intrinsic and Extrinsic Noise in Gene Expression.

Baudrimont A, Jaquet V, Wallerich S, Voegeli S, Becskei A.

Cell Rep. 2019 Mar 26;26(13):3752-3761.e5. doi: 10.1016/j.celrep.2019.03.001.

8.

Potential benefits and harms of NADPH oxidase type 4 in the kidneys and cardiovascular system.

Rajaram RD, Dissard R, Jaquet V, de Seigneux S.

Nephrol Dial Transplant. 2019 Apr 1;34(4):567-576. doi: 10.1093/ndt/gfy161.

PMID:
29931336
9.

Corrigendum to "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)" [Redox Biol. 13 (2017) 94-162].

Egea J, Fabregat I, Frapart YM, Ghezzi P, Görlach A, Kietzmann T, Kubaichuk K, Knaus UG, Lopez MG, Olaso-Gonzalez G, Petry A, Schulz R, Vina J, Winyard P, Abbas K, Ademowo OS, Afonso CB, Andreadou I, Antelmann H, Antunes F, Aslan M, Bachschmid MM, Barbosa RM, Belousov V, Berndt C, Bernlohr D, Bertrán E, Bindoli A, Bottari SP, Brito PM, Carrara G, Casas AI, Chatzi A, Chondrogianni N, Conrad M, Cooke MS, Costa JG, Cuadrado A, My-Chan Dang P, De Smet B, Debelec-Butuner B, Dias IHK, Dunn JD, Edson AJ, El Assar M, El-Benna J, Ferdinandy P, Fernandes AS, Fladmark KE, Förstermann U, Giniatullin R, Giricz Z, Görbe A, Griffiths H, Hampl V, Hanf A, Herget J, Hernansanz-Agustín P, Hillion M, Huang J, Ilikay S, Jansen-Dürr P, Jaquet V, Joles JA, Kalyanaraman B, Kaminskyy D, Karbaschi M, Kleanthous M, Klotz LO, Korac B, Korkmaz KS, Koziel R, Kračun D, Krause KH, Křen V, Krieg T, Laranjinha J, Lazou A, Li H, Martínez-Ruiz A, Matsui R, McBean GJ, Meredith SP, Messens J, Miguel V, Mikhed Y, Milisav I, Milković L, Miranda-Vizuete A, Mojović M, Monsalve M, Mouthuy PA, Mulvey J, Münzel T, Muzykantov V, Nguyen ITN, Oelze M, Oliveira NG, Palmeira CM, Papaevgeniou N, Pavićević A, Pedre B, Peyrot F, Phylactides M, Pircalabioru GG, Pitt AR, Poulsen HE, Prieto I, Rigobello MP, Robledinos-Antón N, Rodríguez-Mañas L, Rolo AP, Rousset F, Ruskovska T, Saraiva N, Sasson S, Schröder K, Semen K, Seredenina T, Shakirzyanova A, Smith GL, Soldati T, Sousa BC, Spickett CM, Stancic A, Stasia MJ, Steinbrenner H, Stepanić V, Steven S, Tokatlidis K, Tuncay E, Turan B, Ursini F, Vacek J, Vajnerova O, Valentová K, Van Breusegem F, Varisli L, Veal EA, Yalçın AS, Yelisyeyeva O, Žarković N, Zatloukalová M, Zielonka J, Touyz RM, Papapetropoulos A, Grune T, Lamas S, Schmidt HHHW, Di Lisa F, Daiber A.

Redox Biol. 2018 Apr;14:694-696. doi: 10.1016/j.redox.2017.10.001. Epub 2017 Oct 26. No abstract available.

10.

NADPH oxidases as drug targets and biomarkers in neurodegenerative diseases: What is the evidence?

Sorce S, Stocker R, Seredenina T, Holmdahl R, Aguzzi A, Chio A, Depaulis A, Heitz F, Olofsson P, Olsson T, Duveau V, Sanoudou D, Skosgater S, Vlahou A, Wasquel D, Krause KH, Jaquet V.

Free Radic Biol Med. 2017 Nov;112:387-396. doi: 10.1016/j.freeradbiomed.2017.08.006. Epub 2017 Aug 12. Review.

11.

Decreased NOX2 expression in the brain of patients with bipolar disorder: association with valproic acid prescription and substance abuse.

Seredenina T, Sorce S, Herrmann FR, Ma Mulone XJ, Plastre O, Aguzzi A, Jaquet V, Krause KH.

Transl Psychiatry. 2017 Aug 15;7(8):e1206. doi: 10.1038/tp.2017.175.

12.

Multiplexed gene control reveals rapid mRNA turnover.

Baudrimont A, Voegeli S, Viloria EC, Stritt F, Lenon M, Wada T, Jaquet V, Becskei A.

Sci Adv. 2017 Jul 12;3(7):e1700006. doi: 10.1126/sciadv.1700006. eCollection 2017 Jul.

13.

Transcription factor NRF2 controls the fate of neural stem cells in the subgranular zone of the hippocampus.

Robledinos-Antón N, Rojo AI, Ferreiro E, Núñez Á, Krause KH, Jaquet V, Cuadrado A.

Redox Biol. 2017 Oct;13:393-401. doi: 10.1016/j.redox.2017.06.010. Epub 2017 Jun 27.

14.

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).

Egea J, Fabregat I, Frapart YM, Ghezzi P, Görlach A, Kietzmann T, Kubaichuk K, Knaus UG, Lopez MG, Olaso-Gonzalez G, Petry A, Schulz R, Vina J, Winyard P, Abbas K, Ademowo OS, Afonso CB, Andreadou I, Antelmann H, Antunes F, Aslan M, Bachschmid MM, Barbosa RM, Belousov V, Berndt C, Bernlohr D, Bertrán E, Bindoli A, Bottari SP, Brito PM, Carrara G, Casas AI, Chatzi A, Chondrogianni N, Conrad M, Cooke MS, Costa JG, Cuadrado A, My-Chan Dang P, De Smet B, Debelec-Butuner B, Dias IHK, Dunn JD, Edson AJ, El Assar M, El-Benna J, Ferdinandy P, Fernandes AS, Fladmark KE, Förstermann U, Giniatullin R, Giricz Z, Görbe A, Griffiths H, Hampl V, Hanf A, Herget J, Hernansanz-Agustín P, Hillion M, Huang J, Ilikay S, Jansen-Dürr P, Jaquet V, Joles JA, Kalyanaraman B, Kaminskyy D, Karbaschi M, Kleanthous M, Klotz LO, Korac B, Korkmaz KS, Koziel R, Kračun D, Krause KH, Křen V, Krieg T, Laranjinha J, Lazou A, Li H, Martínez-Ruiz A, Matsui R, McBean GJ, Meredith SP, Messens J, Miguel V, Mikhed Y, Milisav I, Milković L, Miranda-Vizuete A, Mojović M, Monsalve M, Mouthuy PA, Mulvey J, Münzel T, Muzykantov V, Nguyen ITN, Oelze M, Oliveira NG, Palmeira CM, Papaevgeniou N, Pavićević A, Pedre B, Peyrot F, Phylactides M, Pircalabioru GG, Pitt AR, Poulsen HE, Prieto I, Rigobello MP, Robledinos-Antón N, Rodríguez-Mañas L, Rolo AP, Rousset F, Ruskovska T, Saraiva N, Sasson S, Schröder K, Semen K, Seredenina T, Shakirzyanova A, Smith GL, Soldati T, Sousa BC, Spickett CM, Stancic A, Stasia MJ, Steinbrenner H, Stepanić V, Steven S, Tokatlidis K, Tuncay E, Turan B, Ursini F, Vacek J, Vajnerova O, Valentová K, Van Breusegem F, Varisli L, Veal EA, Yalçın AS, Yelisyeyeva O, Žarković N, Zatloukalová M, Zielonka J, Touyz RM, Papapetropoulos A, Grune T, Lamas S, Schmidt HHHW, Di Lisa F, Daiber A.

Redox Biol. 2017 Oct;13:94-162. doi: 10.1016/j.redox.2017.05.007. Epub 2017 May 18. Review. Erratum in: Redox Biol. 2018 Apr;14 :694-696.

15.

Decreased neural precursor cell pool in NADPH oxidase 2-deficiency: From mouse brain to neural differentiation of patient derived iPSC.

Nayernia Z, Colaianna M, Robledinos-Antón N, Gutzwiller E, Sloan-Béna F, Stathaki E, Hibaoui Y, Cuadrado A, Hescheler J, Stasia MJ, Saric T, Jaquet V, Krause KH.

Redox Biol. 2017 Oct;13:82-93. doi: 10.1016/j.redox.2017.04.026. Epub 2017 Apr 24.

16.

Measurement of bistability in a multidimensional parameter space.

Jaquet V, Hsu C, Becskei A.

Integr Biol (Camb). 2017 Feb 20;9(2):167-177. doi: 10.1039/c6ib00242k.

PMID:
28134382
17.

Contribution of Bistability and Noise to Cell Fate Transitions Determined by Feedback Opening.

Hsu C, Jaquet V, Maleki F, Becskei A.

J Mol Biol. 2016 Oct 9;428(20):4115-4128. doi: 10.1016/j.jmb.2016.07.024. Epub 2016 Aug 4.

18.

The oxidative stress theory of disease: levels of evidence and epistemological aspects.

Ghezzi P, Jaquet V, Marcucci F, Schmidt HHHW.

Br J Pharmacol. 2017 Jun;174(12):1784-1796. doi: 10.1111/bph.13544. Epub 2016 Aug 4. Review.

19.

Protein Dimerization Generates Bistability in Positive Feedback Loops.

Hsu C, Jaquet V, Gencoglu M, Becskei A.

Cell Rep. 2016 Aug 2;16(5):1204-1210. doi: 10.1016/j.celrep.2016.06.072. Epub 2016 Jul 14.

20.

Evaluation of NADPH oxidases as drug targets in a mouse model of familial amyotrophic lateral sclerosis.

Seredenina T, Nayernia Z, Sorce S, Maghzal GJ, Filippova A, Ling SC, Basset O, Plastre O, Daali Y, Rushing EJ, Giordana MT, Cleveland DW, Aguzzi A, Stocker R, Krause KH, Jaquet V.

Free Radic Biol Med. 2016 Aug;97:95-108. doi: 10.1016/j.freeradbiomed.2016.05.016. Epub 2016 May 19.

21.

Microglia antioxidant systems and redox signalling.

Vilhardt F, Haslund-Vinding J, Jaquet V, McBean G.

Br J Pharmacol. 2017 Jun;174(12):1719-1732. doi: 10.1111/bph.13426. Epub 2016 Mar 3. Review.

22.

NADPH oxidases in oxidant production by microglia: activating receptors, pharmacology and association with disease.

Haslund-Vinding J, McBean G, Jaquet V, Vilhardt F.

Br J Pharmacol. 2017 Jun;174(12):1733-1749. doi: 10.1111/bph.13425. Epub 2016 Feb 26. Review.

23.

Reactive Oxygen-Related Diseases: Therapeutic Targets and Emerging Clinical Indications.

Casas AI, Dao VT, Daiber A, Maghzal GJ, Di Lisa F, Kaludercic N, Leach S, Cuadrado A, Jaquet V, Seredenina T, Krause KH, López MG, Stocker R, Ghezzi P, Schmidt HH.

Antioxid Redox Signal. 2015 Nov 10;23(14):1171-85. doi: 10.1089/ars.2015.6433. Review.

24.

Response to Pick.

Jaquet V, Rutter AR.

Antioxid Redox Signal. 2015 Nov 20;23(15):1251-3. doi: 10.1089/ars.2015.6565.

PMID:
26566578
25.

Pharmacology and Clinical Drug Candidates in Redox Medicine.

Dao VT, Casas AI, Maghzal GJ, Seredenina T, Kaludercic N, Robledinos-Anton N, Di Lisa F, Stocker R, Ghezzi P, Jaquet V, Cuadrado A, Schmidt HH.

Antioxid Redox Signal. 2015 Nov 10;23(14):1113-29. doi: 10.1089/ars.2015.6430. Epub 2015 Nov 6. Review.

26.

Challenges, Progresses, and Promises for Developing Future NADPH Oxidase Therapeutics.

Bedard K, Whitehouse S, Jaquet V.

Antioxid Redox Signal. 2015 Aug 10;23(5):355-7. doi: 10.1089/ars.2015.6450.

PMID:
26207329
27.

Discovery of GSK2795039, a Novel Small Molecule NADPH Oxidase 2 Inhibitor.

Hirano K, Chen WS, Chueng AL, Dunne AA, Seredenina T, Filippova A, Ramachandran S, Bridges A, Chaudry L, Pettman G, Allan C, Duncan S, Lee KC, Lim J, Ma MT, Ong AB, Ye NY, Nasir S, Mulyanidewi S, Aw CC, Oon PP, Liao S, Li D, Johns DG, Miller ND, Davies CH, Browne ER, Matsuoka Y, Chen DW, Jaquet V, Rutter AR.

Antioxid Redox Signal. 2015 Aug 10;23(5):358-74. doi: 10.1089/ars.2014.6202.

28.

A subset of N-substituted phenothiazines inhibits NADPH oxidases.

Seredenina T, Chiriano G, Filippova A, Nayernia Z, Mahiout Z, Fioraso-Cartier L, Plastre O, Scapozza L, Krause KH, Jaquet V.

Free Radic Biol Med. 2015 Sep;86:239-49. doi: 10.1016/j.freeradbiomed.2015.05.023. Epub 2015 May 23.

PMID:
26013584
29.

Lentivector Knockdown of CCR5 in Hematopoietic Stem and Progenitor Cells Confers Functional and Persistent HIV-1 Resistance in Humanized Mice.

Myburgh R, Ivic S, Pepper MS, Gers-Huber G, Li D, Audigé A, Rochat MA, Jaquet V, Regenass S, Manz MG, Salmon P, Krause KH, Speck RF.

J Virol. 2015 Jul;89(13):6761-72. doi: 10.1128/JVI.00277-15. Epub 2015 Apr 22.

30.

[ROS and NADPH oxidase: key regulators of tumor vascularisation].

Garrido-Urbani S, Jaquet V, Imhof BA.

Med Sci (Paris). 2014 Apr;30(4):415-21. doi: 10.1051/medsci/20143004016. Epub 2014 May 5. Review. French.

31.

New insights on NOX enzymes in the central nervous system.

Nayernia Z, Jaquet V, Krause KH.

Antioxid Redox Signal. 2014 Jun 10;20(17):2815-37. doi: 10.1089/ars.2013.5703. Epub 2014 Jan 16. Review.

32.

Role of NADPH oxidase isoforms NOX1, NOX2 and NOX4 in myocardial ischemia/reperfusion injury.

Braunersreuther V, Montecucco F, Asrih M, Pelli G, Galan K, Frias M, Burger F, Quinderé AL, Montessuit C, Krause KH, Mach F, Jaquet V.

J Mol Cell Cardiol. 2013 Nov;64:99-107. doi: 10.1016/j.yjmcc.2013.09.007. Epub 2013 Sep 16. Erratum in: J Mol Cell Cardiol. 2014 Jan;66:189. Ashri, Mohammed [corrected to Asrih, Mohamed].

PMID:
24051369
33.

Molecular imaging reveals rapid reduction of endothelial activation in early atherosclerosis with apocynin independent of antioxidative properties.

Khanicheh E, Qi Y, Xie A, Mitterhuber M, Xu L, Mochizuki M, Daali Y, Jaquet V, Krause KH, Ruggeri ZM, Kuster GM, Lindner JR, Kaufmann BA.

Arterioscler Thromb Vasc Biol. 2013 Sep;33(9):2187-92. doi: 10.1161/ATVBAHA.113.301710. Epub 2013 Aug 1.

34.

Detection of reactive oxygen species derived from the family of NOX NADPH oxidases.

Maghzal GJ, Krause KH, Stocker R, Jaquet V.

Free Radic Biol Med. 2012 Nov 15;53(10):1903-18. doi: 10.1016/j.freeradbiomed.2012.09.002. Epub 2012 Sep 13. Review.

PMID:
22982596
35.

NADPH oxidase elevations in pyramidal neurons drive psychosocial stress-induced neuropathology.

Schiavone S, Jaquet V, Sorce S, Dubois-Dauphin M, Hultqvist M, Bäckdahl L, Holmdahl R, Colaianna M, Cuomo V, Trabace L, Krause KH.

Transl Psychiatry. 2012 May 8;2:e111. doi: 10.1038/tp.2012.36.

36.

Severe life stress and oxidative stress in the brain: from animal models to human pathology.

Schiavone S, Jaquet V, Trabace L, Krause KH.

Antioxid Redox Signal. 2013 Apr 20;18(12):1475-90. doi: 10.1089/ars.2012.4720. Epub 2012 Aug 6. Review.

37.

Cell-free screening for NOX inhibitors.

Bedard K, Jaquet V.

Chem Biol. 2012 Jun 22;19(6):664-5. doi: 10.1016/j.chembiol.2012.06.002.

38.

Targeting NOX enzymes in the central nervous system: therapeutic opportunities.

Sorce S, Krause KH, Jaquet V.

Cell Mol Life Sci. 2012 Jul;69(14):2387-407. doi: 10.1007/s00018-012-1014-5. Epub 2012 May 30. Review.

PMID:
22643836
39.

MALAT-1, a non protein-coding RNA is upregulated in the cerebellum, hippocampus and brain stem of human alcoholics.

Kryger R, Fan L, Wilce PA, Jaquet V.

Alcohol. 2012 Nov;46(7):629-34. doi: 10.1016/j.alcohol.2012.04.002. Epub 2012 May 4.

PMID:
22560368
40.

Stochastic signalling rewires the interaction map of a multiple feedback network during yeast evolution.

Hsu C, Scherrer S, Buetti-Dinh A, Ratna P, Pizzolato J, Jaquet V, Becskei A.

Nat Commun. 2012 Feb 21;3:682. doi: 10.1038/ncomms1687.

41.

NOX5: from basic biology to signaling and disease.

Bedard K, Jaquet V, Krause KH.

Free Radic Biol Med. 2012 Feb 15;52(4):725-34. doi: 10.1016/j.freeradbiomed.2011.11.023. Epub 2011 Dec 14. Review.

PMID:
22182486
42.

NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action.

Jaquet V, Marcoux J, Forest E, Leidal KG, McCormick S, Westermaier Y, Perozzo R, Plastre O, Fioraso-Cartier L, Diebold B, Scapozza L, Nauseef WM, Fieschi F, Krause KH, Bedard K.

Br J Pharmacol. 2011 Sep;164(2b):507-20. doi: 10.1111/j.1476-5381.2011.01439.x.

43.

Reactive oxygen species in myocardial reperfusion injury: from physiopathology to therapeutic approaches.

Braunersreuther V, Jaquet V.

Curr Pharm Biotechnol. 2012 Jan;13(1):97-114. Review.

PMID:
21470157
44.

The NADPH oxidase NOX2 controls glutamate release: a novel mechanism involved in psychosis-like ketamine responses.

Sorce S, Schiavone S, Tucci P, Colaianna M, Jaquet V, Cuomo V, Dubois-Dauphin M, Trabace L, Krause KH.

J Neurosci. 2010 Aug 25;30(34):11317-25. doi: 10.1523/JNEUROSCI.1491-10.2010.

45.

Editorial: Genetic mapping--the path of discovery for novel functions of the NOX NADPH oxidases.

Jaquet V, Bedard K.

J Leukoc Biol. 2009 Sep;86(3):461-3. doi: 10.1189/jlb.0409243. No abstract available.

PMID:
19720613
46.

Involvement of NOX2 in the development of behavioral and pathologic alterations in isolated rats.

Schiavone S, Sorce S, Dubois-Dauphin M, Jaquet V, Colaianna M, Zotti M, Cuomo V, Trabace L, Krause KH.

Biol Psychiatry. 2009 Aug 15;66(4):384-92. doi: 10.1016/j.biopsych.2009.04.033. Epub 2009 Jun 26.

PMID:
19559404
47.

Three common polymorphisms in the CYBA gene form a haplotype associated with decreased ROS generation.

Bedard K, Attar H, Bonnefont J, Jaquet V, Borel C, Plastre O, Stasia MJ, Antonarakis SE, Krause KH.

Hum Mutat. 2009 Jul;30(7):1123-33. doi: 10.1002/humu.21029.

PMID:
19388116
48.

Small-molecule NOX inhibitors: ROS-generating NADPH oxidases as therapeutic targets.

Jaquet V, Scapozza L, Clark RA, Krause KH, Lambeth JD.

Antioxid Redox Signal. 2009 Oct;11(10):2535-52. doi: 10.1089/ARS.2009.2585. Review.

PMID:
19309261
49.

NADPH oxidase 1 deficiency alters caveolin phosphorylation and angiotensin II-receptor localization in vascular smooth muscle.

Basset O, Deffert C, Foti M, Bedard K, Jaquet V, Ogier-Denis E, Krause KH.

Antioxid Redox Signal. 2009 Oct;11(10):2371-84. doi: 10.1089/ARS.2009.2584.

PMID:
19309260
50.

Hyperinflammation in chronic granulomatous disease and anti-inflammatory role of the phagocyte NADPH oxidase.

Schäppi MG, Jaquet V, Belli DC, Krause KH.

Semin Immunopathol. 2008 Jul;30(3):255-71. doi: 10.1007/s00281-008-0119-2. Epub 2008 May 29. Review.

PMID:
18509648

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