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Items: 27

1.

Genome organization and DNA accessibility control antigenic variation in trypanosomes.

Müller LSM, Cosentino RO, Förstner KU, Guizetti J, Wedel C, Kaplan N, Janzen CJ, Arampatzi P, Vogel J, Steinbiss S, Otto TD, Saliba AE, Sebra RP, Siegel TN.

Nature. 2018 Nov;563(7729):121-125. doi: 10.1038/s41586-018-0619-8. Epub 2018 Oct 17.

PMID:
30333624
2.

TelAP1 links telomere complexes with developmental expression site silencing in African trypanosomes.

Reis H, Schwebs M, Dietz S, Janzen CJ, Butter F.

Nucleic Acids Res. 2018 Apr 6;46(6):2820-2833. doi: 10.1093/nar/gky028.

3.

The nuclear proteome of Trypanosoma brucei.

Goos C, Dejung M, Janzen CJ, Butter F, Kramer S.

PLoS One. 2017 Jul 20;12(7):e0181884. doi: 10.1371/journal.pone.0181884. eCollection 2017.

4.

A quorum sensing-independent path to stumpy development in Trypanosoma brucei.

Zimmermann H, Subota I, Batram C, Kramer S, Janzen CJ, Jones NG, Engstler M.

PLoS Pathog. 2017 Apr 10;13(4):e1006324. doi: 10.1371/journal.ppat.1006324. eCollection 2017 Apr.

5.

Two flagellar BAR domain proteins in Trypanosoma brucei with stage-specific regulation.

Cicova Z, Dejung M, Skalicky T, Eisenhuth N, Hanselmann S, Morriswood B, Figueiredo LM, Butter F, Janzen CJ.

Sci Rep. 2016 Oct 25;6:35826. doi: 10.1038/srep35826.

6.

Quantitative Proteomics Uncovers Novel Factors Involved in Developmental Differentiation of Trypanosoma brucei.

Dejung M, Subota I, Bucerius F, Dindar G, Freiwald A, Engstler M, Boshart M, Butter F, Janzen CJ.

PLoS Pathog. 2016 Feb 24;12(2):e1005439. doi: 10.1371/journal.ppat.1005439. eCollection 2016 Feb.

7.

Fragment ion patchwork quantification for measuring site-specific acetylation degrees.

ElBashir R, Vanselow JT, Kraus A, Janzen CJ, Siegel TN, Schlosser A.

Anal Chem. 2015 Oct 6;87(19):9939-45. doi: 10.1021/acs.analchem.5b02517.

PMID:
26335048
8.

Structure-guided mutational analysis reveals the functional requirements for product specificity of DOT1 enzymes.

Dindar G, Anger AM, Mehlhorn C, Hake SB, Janzen CJ.

Nat Commun. 2014 Nov 12;5:5313. doi: 10.1038/ncomms6313.

PMID:
25387577
9.

Expression site attenuation mechanistically links antigenic variation and development in Trypanosoma brucei.

Batram C, Jones NG, Janzen CJ, Markert SM, Engstler M.

Elife. 2014 May 20;3:e02324. doi: 10.7554/eLife.02324.

10.

Characterization of two different Asf1 histone chaperones with distinct cellular localizations and functions in Trypanosoma brucei.

Pascoalino B, Dindar G, Vieira-da-Rocha JP, Machado CR, Janzen CJ, Schenkman S.

Nucleic Acids Res. 2014 Mar;42(5):2906-18. doi: 10.1093/nar/gkt1267. Epub 2013 Dec 9.

11.

Comparative proteomics of two life cycle stages of stable isotope-labeled Trypanosoma brucei reveals novel components of the parasite's host adaptation machinery.

Butter F, Bucerius F, Michel M, Cicova Z, Mann M, Janzen CJ.

Mol Cell Proteomics. 2013 Jan;12(1):172-9. doi: 10.1074/mcp.M112.019224. Epub 2012 Oct 22.

12.

DOT1A-dependent H3K76 methylation is required for replication regulation in Trypanosoma brucei.

Gassen A, Brechtefeld D, Schandry N, Arteaga-Salas JM, Israel L, Imhof A, Janzen CJ.

Nucleic Acids Res. 2012 Nov 1;40(20):10302-11. doi: 10.1093/nar/gks801. Epub 2012 Aug 31.

13.

Regulation and spatial organization of PCNA in Trypanosoma brucei.

Kaufmann D, Gassen A, Maiser A, Leonhardt H, Janzen CJ.

Biochem Biophys Res Commun. 2012 Mar 23;419(4):698-702. doi: 10.1016/j.bbrc.2012.02.082. Epub 2012 Feb 21.

PMID:
22387477
14.

Heterologous expression reveals distinct enzymatic activities of two DOT1 histone methyltransferases of Trypanosoma brucei.

Frederiks F, van Welsem T, Oudgenoeg G, Heck AJ, Janzen CJ, van Leeuwen F.

J Cell Sci. 2010 Dec 1;123(Pt 23):4019-23. doi: 10.1242/jcs.073882.

15.

Reliable quantification of cell cycle-dependent mRNA abundance using fluorescence-activated cell sorting in Trypanosoma brucei.

Bucerius F, Kador M, Boshart M, Janzen CJ.

Mol Biochem Parasitol. 2011 Feb;175(2):205-8. doi: 10.1016/j.molbiopara.2010.10.001. Epub 2010 Oct 8.

PMID:
20933544
16.

Epigenetic regulation in African trypanosomes: a new kid on the block.

Figueiredo LM, Cross GA, Janzen CJ.

Nat Rev Microbiol. 2009 Jul;7(7):504-13. doi: 10.1038/nrmicro2149. Review.

PMID:
19528957
17.

A histone methyltransferase modulates antigenic variation in African trypanosomes.

Figueiredo LM, Janzen CJ, Cross GA.

PLoS Biol. 2008 Jul 1;6(7):e161. doi: 10.1371/journal.pbio.0060161.

18.

Trypanosome H2Bv replaces H2B in nucleosomes enriched for H3 K4 and K76 trimethylation.

Mandava V, Janzen CJ, Cross GA.

Biochem Biophys Res Commun. 2008 Apr 18;368(4):846-51. doi: 10.1016/j.bbrc.2008.01.144. Epub 2008 Feb 7.

19.

Acetylation of histone H4K4 is cell cycle regulated and mediated by HAT3 in Trypanosoma brucei.

Siegel TN, Kawahara T, Degrasse JA, Janzen CJ, Horn D, Cross GA.

Mol Microbiol. 2008 Feb;67(4):762-71. doi: 10.1111/j.1365-2958.2007.06079.x. Epub 2007 Dec 30.

20.

Histone modifications in Trypanosoma brucei.

Mandava V, Fernandez JP, Deng H, Janzen CJ, Hake SB, Cross GA.

Mol Biochem Parasitol. 2007 Nov;156(1):41-50. Epub 2007 Jul 17.

21.

Trypanosoma brucei 29-13 strain is inducible in but not permissive for the tsetse fly vector.

Herder S, Votýpka J, Jirků M, Rádrová J, Janzen CJ, Lukes J.

Exp Parasitol. 2007 Sep;117(1):111-4. Epub 2007 Jun 3.

PMID:
17603043
22.

An adenosine-to-inosine tRNA-editing enzyme that can perform C-to-U deamination of DNA.

Rubio MA, Pastar I, Gaston KW, Ragone FL, Janzen CJ, Cross GA, Papavasiliou FN, Alfonzo JD.

Proc Natl Acad Sci U S A. 2007 May 8;104(19):7821-6. Epub 2007 May 1.

23.
24.

Expression site silencing and life-cycle progression appear normal in Argonaute1-deficient Trypanosoma brucei.

Janzen CJ, van Deursen F, Shi H, Cross GAM, Matthews KR, Ullu E.

Mol Biochem Parasitol. 2006 Sep;149(1):102-107. doi: 10.1016/j.molbiopara.2006.04.005. Epub 2006 May 12. No abstract available.

25.

Unusual histone modifications in Trypanosoma brucei.

Janzen CJ, Fernandez JP, Deng H, Diaz R, Hake SB, Cross GA.

FEBS Lett. 2006 Apr 17;580(9):2306-10. Epub 2006 Mar 24.

26.

Histone H2AZ dimerizes with a novel variant H2B and is enriched at repetitive DNA in Trypanosoma brucei.

Lowell JE, Kaiser F, Janzen CJ, Cross GA.

J Cell Sci. 2005 Dec 15;118(Pt 24):5721-30. Epub 2005 Nov 22.

27.

Telomere length regulation and transcriptional silencing in KU80-deficient Trypanosoma brucei.

Janzen CJ, Lander F, Dreesen O, Cross GA.

Nucleic Acids Res. 2004 Dec 15;32(22):6575-84. Print 2004.

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