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Items: 1 to 50 of 289

1.

Distinct autophagy-apoptosis related pathways activated by Multi-walled (NM 400) and Single-walled carbon nanotubes (NIST-SRM2483) in human bronchial epithelial (16HBE14o-) cells.

Ghosh M, Murugadoss S, Janssen L, Cokic S, Mathyssen C, Van Landuyt K, Janssens W, Carpentier S, Godderis L, Hoet P.

J Hazard Mater. 2019 Nov 20:121691. doi: 10.1016/j.jhazmat.2019.121691. [Epub ahead of print]

PMID:
31791862
2.

Exacerbations of chronic obstructive pulmonary disease: time to rename.

Bafadhel M, Criner G, Dransfield MT, Janssens W, McDonald VM, Vogelmeier CF, Russell RE, Collis P.

Lancet Respir Med. 2019 Nov 27. pii: S2213-2600(19)30414-X. doi: 10.1016/S2213-2600(19)30414-X. [Epub ahead of print] No abstract available.

PMID:
31786125
3.

Treatment failure and hospital readmissions in severe COPD exacerbations treated with azithromycin versus placebo - a post-hoc analysis of the BACE randomized controlled trial.

Vermeersch K, Belmans A, Bogaerts K, Gyselinck I, Cardinaels N, Gabrovska M, Aumann J, Demedts IK, Corhay JL, Marchand E, Slabbynck H, Haenebalcke C, Vermeersch S, Verleden GM, Troosters T, Ninane V, Brusselle GG, Janssens W; BACE trial investigators.

Respir Res. 2019 Oct 29;20(1):237. doi: 10.1186/s12931-019-1208-6.

4.

Vitamin D Modulates the Response of Bronchial Epithelial Cells Exposed to Cigarette Smoke Extract.

Mathyssen C, Serré J, Sacreas A, Everaerts S, Maes K, Verleden S, Verlinden L, Verstuyf A, Pilette C, Gayan-Ramirez G, Vanaudenaerde B, Janssens W.

Nutrients. 2019 Sep 6;11(9). pii: E2138. doi: 10.3390/nu11092138.

5.

Airway morphometry in COPD with bronchiectasis: a view on all airway generations.

Everaerts S, McDonough JE, Verleden SE, Josipovic I, Boone M, Dubbeldam A, Mathyssen C, Serré J, Dupont LJ, Gayan-Ramirez G, Verschakelen J, Hogg JC, Verleden GM, Vanaudenaerde BM, Janssens W.

Eur Respir J. 2019 Nov 7;54(5). pii: 1802166. doi: 10.1183/13993003.02166-2018. Print 2019 Nov.

PMID:
31467117
6.

Spirometric indices of early airflow impairment in individuals at risk of developing COPD: Spirometry beyond FEV1/FVC.

Hoesterey D, Das N, Janssens W, Buhr RG, Martinez FJ, Cooper CB, Tashkin DP, Barjaktarevic I.

Respir Med. 2019 Sep;156:58-68. doi: 10.1016/j.rmed.2019.08.004. Epub 2019 Aug 9. Review.

PMID:
31437649
7.

Low Vitamin K Status Is Associated with Increased Elastin Degradation in Chronic Obstructive Pulmonary Disease.

Piscaer I, van den Ouweland JMW, Vermeersch K, Reynaert NL, Franssen FME, Keene S, Wouters EFM, Janssens W, Vermeer C, Janssen R.

J Clin Med. 2019 Jul 27;8(8). pii: E1116. doi: 10.3390/jcm8081116.

8.

Targeting Vitamin D Deficiency to Limit Exacerbations in Respiratory Diseases: Utopia or Strategy With Potential?

Maes K, Serré J, Mathyssen C, Janssens W, Gayan-Ramirez G.

Calcif Tissue Int. 2019 Jul 26. doi: 10.1007/s00223-019-00591-4. [Epub ahead of print] Review.

PMID:
31350569
10.

Safety and Dose Study of Targeted Lung Denervation in Moderate/Severe COPD Patients.

Valipour A, Shah PL, Pison C, Ninane V, Janssens W, Perez T, Kessler R, Deslee G, Garner J, Abele C, Hartman JE, Slebos DJ; On behalf of the AIRFLOW-1 Study Group.

Respiration. 2019;98(4):329-339. doi: 10.1159/000500463. Epub 2019 Jun 20.

11.

Artificial intelligence for pulmonary function test interpretation.

Topalovic M, Das N, Janssens W; authors.

Eur Respir J. 2019 Jun 5;53(6). pii: 1900782. doi: 10.1183/13993003.00782-2019. Print 2019 Jun. No abstract available.

PMID:
31167887
12.

Health status deterioration in subjects with mild to moderate airflow obstruction, a six years observational study.

Rodrigues FM, Demeyer H, Loeckx M, Hornikx M, Van Remoortel H, Janssens W, Troosters T.

Respir Res. 2019 May 18;20(1):93. doi: 10.1186/s12931-019-1061-7.

13.

Shared Learnings on the New EMA First-in-Human and Early Clinical Trial Guideline: Proceedings From a DIAlogue Session at DIA Europe 2018.

van der Laan JW, Benson CT, Janssens W, Bos J, Stahl E, Brady JT, Wändel-Liminga U, Corriol-Rohou S, Forster R, Hartmann A, Pertel PE, Robertson SM, Silva-Lima B, Malik RE, Chibout SD.

Ther Innov Regul Sci. 2019 May 13:2168479019843514. doi: 10.1177/2168479019843514. [Epub ahead of print]

PMID:
31084267
14.

Strategies to Increase Physical Activity in Chronic Respiratory Diseases.

Troosters T, Blondeel A, Rodrigues FM, Janssens W, Demeyer H.

Clin Chest Med. 2019 Jun;40(2):397-404. doi: 10.1016/j.ccm.2019.02.017. Review.

PMID:
31078217
15.

Azithromycin during Acute Chronic Obstructive Pulmonary Disease Exacerbations Requiring Hospitalization (BACE). A Multicenter, Randomized, Double-Blind, Placebo-controlled Trial.

Vermeersch K, Gabrovska M, Aumann J, Demedts IK, Corhay JL, Marchand E, Slabbynck H, Haenebalcke C, Haerens M, Hanon S, Jordens P, Peché R, Fremault A, Lauwerier T, Delporte A, Vandenberk B, Willems R, Everaerts S, Belmans A, Bogaerts K, Verleden GM, Troosters T, Ninane V, Brusselle GG, Janssens W.

Am J Respir Crit Care Med. 2019 Oct 1;200(7):857-868. doi: 10.1164/rccm.201901-0094OC.

PMID:
31046405
16.

Multidisciplinary Perspectives on the Importance of Physical Activity in COPD.

Miravitlles M, Troosters T, Janssens W, Ancochea J.

Arch Bronconeumol. 2019 Nov;55(11):551-552. doi: 10.1016/j.arbres.2019.03.010. Epub 2019 Apr 11. English, Spanish. No abstract available.

17.

The past, present and future of pulmonary rehabilitation.

Troosters T, Blondeel A, Janssens W, Demeyer H.

Respirology. 2019 Sep;24(9):830-837. doi: 10.1111/resp.13517. Epub 2019 Mar 13. Review.

18.

Area under the forced expiratory flow-volume loop in spirometry indicates severe hyperinflation in COPD patients.

Das N, Topalovic M, Aerts JM, Janssens W.

Int J Chron Obstruct Pulmon Dis. 2019 Feb 14;14:409-418. doi: 10.2147/COPD.S185931. eCollection 2019.

19.

Early integrated palliative care in chronic heart failure and chronic obstructive pulmonary disease: protocol of a feasibility before-after intervention study.

Siouta N, Heylen A, Aertgeerts B, Clement P, Van Cleemput J, Janssens W, Menten J.

Pilot Feasibility Stud. 2019 Feb 21;5:31. doi: 10.1186/s40814-019-0420-y. eCollection 2019.

20.

Artificial intelligence outperforms pulmonologists in the interpretation of pulmonary function tests.

Topalovic M, Das N, Burgel PR, Daenen M, Derom E, Haenebalcke C, Janssen R, Kerstjens HAM, Liistro G, Louis R, Ninane V, Pison C, Schlesser M, Vercauter P, Vogelmeier CF, Wouters E, Wynants J, Janssens W; Pulmonary Function Study Investigators; Pulmonary Function Study Investigators:.

Eur Respir J. 2019 Apr 11;53(4). pii: 1801660. doi: 10.1183/13993003.01660-2018. Print 2019 Apr.

PMID:
30765505
21.

The role of physical activity in the context of pulmonary rehabilitation.

Blondeel A, Demeyer H, Janssens W, Troosters T.

COPD. 2018 Dec;15(6):632-639. doi: 10.1080/15412555.2018.1563060. Epub 2019 Feb 4. Review.

PMID:
30712395
22.

Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis.

Martineau AR, Jolliffe DA, Greenberg L, Aloia JF, Bergman P, Dubnov-Raz G, Esposito S, Ganmaa D, Ginde AA, Goodall EC, Grant CC, Janssens W, Jensen ME, Kerley CP, Laaksi I, Manaseki-Holland S, Mauger D, Murdoch DR, Neale R, Rees JR, Simpson S, Stelmach I, Trilok Kumar G, Urashima M, Camargo CA, Griffiths CJ, Hooper RL.

Health Technol Assess. 2019 Jan;23(2):1-44. doi: 10.3310/hta23020.

23.

The impact of disease-specific fears on outcome measures of pulmonary rehabilitation in patients with COPD.

Reijnders T, Schuler M, Wittmann M, Jelusic D, Troosters T, Janssens W, Stenzel NM, Schultz K, von Leupoldt A.

Respir Med. 2019 Jan;146:87-95. doi: 10.1016/j.rmed.2018.12.004. Epub 2018 Dec 13.

PMID:
30665524
24.

Data on inflammatory cytokines and pathways involved in clearance of Nontypeable Haemophilus influenzae from the lungs during cigarette smoking and vitamin D deficiency.

Serré J, Mathyssen C, Ajime TT, Korf H, Maes K, Heulens N, Gysemans C, Mathieu C, Vanaudenaerde B, Janssens W, Gayan-Ramirez G.

Data Brief. 2018 Dec 18;22:703-708. doi: 10.1016/j.dib.2018.12.048. eCollection 2019 Feb.

25.

Vitamin D to prevent exacerbations of COPD: systematic review and meta-analysis of individual participant data from randomised controlled trials.

Jolliffe DA, Greenberg L, Hooper RL, Mathyssen C, Rafiq R, de Jongh RT, Camargo CA, Griffiths CJ, Janssens W, Martineau AR.

Thorax. 2019 Apr;74(4):337-345. doi: 10.1136/thoraxjnl-2018-212092. Epub 2019 Jan 10.

PMID:
30630893
26.

Six years progression of exercise capacity in subjects with mild to moderate airflow obstruction, smoking and never smoking controls.

Rodrigues FM, Loeckx M, Hornikx M, Van Remoortel H, Louvaris Z, Demeyer H, Janssens W, Troosters T.

PLoS One. 2018 Dec 26;13(12):e0208841. doi: 10.1371/journal.pone.0208841. eCollection 2018.

27.

The likelihood of improving physical activity after pulmonary rehabilitation is increased in patients with COPD who have better exercise tolerance.

Osadnik CR, Loeckx M, Louvaris Z, Demeyer H, Langer D, Rodrigues FM, Janssens W, Vogiatzis I, Troosters T.

Int J Chron Obstruct Pulmon Dis. 2018 Oct 24;13:3515-3527. doi: 10.2147/COPD.S174827. eCollection 2018.

28.
29.

The Impact of Loneliness on Outcomes of Pulmonary Rehabilitation in Patients with COPD.

Reijnders T, Schuler M, Jelusic D, Troosters T, Janssens W, Schultz K, von Leupoldt A.

COPD. 2018 Oct;15(5):446-453. doi: 10.1080/15412555.2018.1471128. Epub 2018 Nov 7.

PMID:
30403542
30.

Airway infection with Nontypeable Haemophilus influenzae is more rapidly eradicated in vitamin D deficient mice.

Serré J, Mathyssen C, Ajime TT, Korf H, Maes K, Heulens N, Gysemans C, Mathieu C, Vanaudenaerde B, Janssens W, Gayan-Ramirez G.

J Steroid Biochem Mol Biol. 2019 Mar;187:42-51. doi: 10.1016/j.jsbmb.2018.10.021. Epub 2018 Nov 3.

PMID:
30399417
31.

Short and long-term effects of pulmonary rehabilitation in interstitial lung diseases: a randomised controlled trial.

Perez-Bogerd S, Wuyts W, Barbier V, Demeyer H, Van Muylem A, Janssens W, Troosters T.

Respir Res. 2018 Sep 20;19(1):182. doi: 10.1186/s12931-018-0884-y.

32.

Long-term antibody persistence against hepatitis B in adolescents 14-15-years of age vaccinated with 4 doses of hexavalent DTPa-HBV-IPV/Hib vaccine in infancy.

Schwarz TF, Behre U, Adelt T, Donner M, Suryakiran PV, Janssens W, Mesaros N, Panzer F.

Hum Vaccin Immunother. 2019;15(1):235-241. doi: 10.1080/21645515.2018.1509658. Epub 2018 Sep 11.

33.

Launching Global Lung Function Initiative reference values in Belgium: tips and tricks.

Derom E, Liistro G, Oostveen E, Marchand E, Bedert L, Peché R, Janssens W; Pulmonary Function Working Group of the Belgian Thoracic Society.

Eur Respir J. 2018 Aug 2;52(2). pii: 1800922. doi: 10.1183/13993003.00922-2018. Print 2018 Aug. No abstract available.

PMID:
30072542
34.

Cigarette Smoke-Induced Emphysema Exhausts Early Cytotoxic CD8+ T Cell Responses against Nascent Lung Cancer Cells.

Kerdidani D, Magkouta S, Chouvardas P, Karavana V, Glynos K, Roumelioti F, Zakynthinos S, Wauters E, Janssens W, Lambrechts D, Kollias G, Tsoumakidou M.

J Immunol. 2018 Sep 1;201(5):1558-1569. doi: 10.4049/jimmunol.1700700. Epub 2018 Jul 23.

35.

RNA-sequencing in non-small cell lung cancer shows gene downregulation of therapeutic targets in tumor tissue compared to non-malignant lung tissue.

Reynders K, Wauters E, Moisse M, Decaluwé H, De Leyn P, Peeters S, Lambrecht M, Nackaerts K, Dooms C, Janssens W, Vansteenkiste J, Lambrechts D, De Ruysscher D.

Radiat Oncol. 2018 Jul 17;13(1):131. doi: 10.1186/s13014-018-1075-1.

36.

Overuse of inhaled corticosteroids in COPD: five questions for withdrawal in daily practice.

Cataldo D, Derom E, Liistro G, Marchand E, Ninane V, Peché R, Slabbynck H, Vincken W, Janssens W.

Int J Chron Obstruct Pulmon Dis. 2018 Jul 5;13:2089-2099. doi: 10.2147/COPD.S164259. eCollection 2018. Review.

37.

Significance of prolonged QTc in acute exacerbations of COPD requiring hospitalization.

Van Oekelen O, Vermeersch K, Everaerts S, Vandenberk B, Willems R, Janssens W.

Int J Chron Obstruct Pulmon Dis. 2018 Jun 14;13:1937-1947. doi: 10.2147/COPD.S157630. eCollection 2018.

38.

Hexavalent vaccines: increasing options for policy-makers and providers. A review of the data supporting interchangeability (substitution with vaccines containing fewer antigens) and mixed schedules from the same manufacturer.

Dolhain J, Janssens W, Mesaros N, Hanssens L, Fierens F.

Expert Rev Vaccines. 2018 Jun;17(6):513-524. doi: 10.1080/14760584.2018.1419070. Epub 2018 Jun 19. Review.

PMID:
29920121
39.

The aging lung: tissue telomere shortening in health and disease.

Everaerts S, Lammertyn EJ, Martens DS, De Sadeleer LJ, Maes K, van Batenburg AA, Goldschmeding R, van Moorsel CHM, Dupont LJ, Wuyts WA, Vos R, Gayan-Ramirez G, Kaminski N, Hogg JC, Janssens W, Verleden GM, Nawrot TS, Verleden SE, McDonough JE, Vanaudenaerde BM.

Respir Res. 2018 May 11;19(1):95. doi: 10.1186/s12931-018-0794-z.

40.

Effect of Bronchodilation, Exercise Training, and Behavior Modification on Symptoms and Physical Activity in Chronic Obstructive Pulmonary Disease.

Troosters T, Maltais F, Leidy N, Lavoie KL, Sedeno M, Janssens W, Garcia-Aymerich J, Erzen D, De Sousa D, Korducki L, Hamilton A, Bourbeau J.

Am J Respir Crit Care Med. 2018 Oct 15;198(8):1021-1032. doi: 10.1164/rccm.201706-1288OC.

PMID:
29664681
41.

How resources determine pulmonary rehabilitation programs: A survey among Belgian chest physicians.

Janssens W, Corhay JL, Bogaerts P, Derom E, Frusch N, Dang DN, Kibanda J, Ruttens D, Thyrion L, Troosters T, Marchand E.

Chron Respir Dis. 2019 Jan-Dec;16:1479972318767732. doi: 10.1177/1479972318767732. Epub 2018 Apr 9.

42.

Do-not-resuscitate orders as part of advance care planning in patients with COPD.

Raskin J, Vermeersch K, Everaerts S, Van Bleyenbergh P, Janssens W.

ERJ Open Res. 2018 Feb 16;4(1). pii: 00116-2017. doi: 10.1183/23120541.00116-2017. eCollection 2018 Jan.

43.

Aspergillus fumigatus Detection and Risk Factors in Patients with COPD-Bronchiectasis Overlap.

Everaerts S, Lagrou K, Vermeersch K, Dupont LJ, Vanaudenaerde BM, Janssens W.

Int J Mol Sci. 2018 Feb 9;19(2). pii: E523. doi: 10.3390/ijms19020523.

44.

Perceptions of healthcare quality in Ghana: Does health insurance status matter?

Duku SKO, Nketiah-Amponsah E, Janssens W, Pradhan M.

PLoS One. 2018 Jan 16;13(1):e0190911. doi: 10.1371/journal.pone.0190911. eCollection 2018.

45.

Artificial intelligence in diagnosis of obstructive lung disease: current status and future potential.

Das N, Topalovic M, Janssens W.

Curr Opin Pulm Med. 2018 Mar;24(2):117-123. doi: 10.1097/MCP.0000000000000459. Review.

PMID:
29251699
46.

Vitamin K deficiency: the linking pin between COPD and cardiovascular diseases?

Piscaer I, Wouters EFM, Vermeer C, Janssens W, Franssen FME, Janssen R.

Respir Res. 2017 Nov 13;18(1):189. doi: 10.1186/s12931-017-0673-z. Review.

47.

Vitamin D supplementation in respiratory diseases: evidence from randomized controlled trials.

Mathyssen C, Gayan-Ramirez G, Bouillon R, Janssens W.

Pol Arch Intern Med. 2017 Nov 30;127(11):775-784. doi: 10.20452/pamw.4134. Epub 2017 Nov 2. Review.

48.

A simple algorithm for the identification of clinical COPD phenotypes.

Burgel PR, Paillasseur JL, Janssens W, Piquet J, Ter Riet G, Garcia-Aymerich J, Cosio B, Bakke P, Puhan MA, Langhammer A, Alfageme I, Almagro P, Ancochea J, Celli BR, Casanova C, de-Torres JP, Decramer M, Echazarreta A, Esteban C, Gomez Punter RM, Han MK, Johannessen A, Kaiser B, Lamprecht B, Lange P, Leivseth L, Marin JM, Martin F, Martinez-Camblor P, Miravitlles M, Oga T, Sofia Ramírez A, Sin DD, Sobradillo P, Soler-Cataluña JJ, Turner AM, Verdu Rivera FJ, Soriano JB, Roche N; Initiatives BPCO, EABPCO, Leuven and 3CIA study groups.

Eur Respir J. 2017 Nov 2;50(5). pii: 1701034. doi: 10.1183/13993003.01034-2017. Print 2017 Nov.

49.

DPP4, the Middle East Respiratory Syndrome Coronavirus Receptor, is Upregulated in Lungs of Smokers and Chronic Obstructive Pulmonary Disease Patients.

Seys LJM, Widagdo W, Verhamme FM, Kleinjan A, Janssens W, Joos GF, Bracke KR, Haagmans BL, Brusselle GG.

Clin Infect Dis. 2018 Jan 6;66(1):45-53. doi: 10.1093/cid/cix741.

PMID:
29020176
50.

Sensitization to Aspergillus fumigatus as a risk factor for bronchiectasis in COPD.

Everaerts S, Lagrou K, Dubbeldam A, Lorent N, Vermeersch K, Van Hoeyveld E, Bossuyt X, Dupont LJ, Vanaudenaerde BM, Janssens W.

Int J Chron Obstruct Pulmon Dis. 2017 Aug 31;12:2629-2638. doi: 10.2147/COPD.S141695. eCollection 2017.

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