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Items: 32

1.

Nitric oxide for inhalation in ST-elevation myocardial infarction (NOMI): a multicentre, double-blind, randomized controlled trial.

Janssens SP, Bogaert J, Zalewski J, Toth A, Adriaenssens T, Belmans A, Bennett J, Claus P, Desmet W, Dubois C, Goetschalckx K, Sinnaeve P, Vandenberghe K, Vermeersch P, Lux A, Szelid Z, Durak M, Lech P, Zmudka K, Pokreisz P, Vranckx P, Merkely B, Bloch KD, Van de Werf F; NOMI investigators .

Eur Heart J. 2018 Aug 1;39(29):2717-2725. doi: 10.1093/eurheartj/ehy232.

PMID:
29800130
2.

Mesenchymal Cell Therapy for Dilated Cardiomyopathy: Time to Test the Water.

Janssens SP.

J Am Coll Cardiol. 2017 Feb 7;69(5):538-540. doi: 10.1016/j.jacc.2016.11.044. No abstract available.

3.

Decreased Soluble Guanylate Cyclase Contributes to Cardiac Dysfunction Induced by Chronic Doxorubicin Treatment in Mice.

Vandenwijngaert S, Swinnen M, Walravens AS, Beerens M, Gillijns H, Caluwé E, Tainsh RE, Nathan DI, Allen K, Brouckaert P, Bartunek J, Scherrer-Crosbie M, Bloch KD, Bloch DB, Janssens SP, Buys ES.

Antioxid Redox Signal. 2017 Feb 1;26(4):153-164. doi: 10.1089/ars.2015.6542. Epub 2016 Sep 8.

4.

Novel MicroRNA Regulators of Atrial Natriuretic Peptide Production.

Wu C, Arora P, Agha O, Hurst LA, Allen K, Nathan DI, Hu D, Jiramongkolchai P, Smith JG, Melander O, Trenson S, Janssens SP, Domian I, Wang TJ, Bloch KD, Buys ES, Bloch DB, Newton-Cheh C.

Mol Cell Biol. 2016 Jun 29;36(14):1977-87. doi: 10.1128/MCB.01114-15. Print 2016 Jul 15.

5.

Concomitant Phosphodiesterase 5 Inhibition Enhances Myocardial Protection by Inhaled Nitric Oxide in Ischemia-Reperfusion Injury.

Lux A, Pokreisz P, Swinnen M, Caluwe E, Gillijns H, Szelid Z, Merkely B, Janssens SP.

J Pharmacol Exp Ther. 2016 Feb;356(2):284-92. doi: 10.1124/jpet.115.227850. Epub 2015 Nov 30.

PMID:
26621143
6.

Fetal rat hearts do not display acute cardiotoxicity in response to maternal Doxorubicin treatment.

Gziri MM, Pokreisz P, De Vos R, Verbeken E, Debiève F, Mertens L, Janssens SP, Amant F.

J Pharmacol Exp Ther. 2013 Sep;346(3):362-9. doi: 10.1124/jpet.113.205419. Epub 2013 Jun 21.

PMID:
23792410
7.

Stem cell therapy for the treatment of myocardial infarction.

Dauwe DF, Janssens SP.

Curr Pharm Des. 2011 Oct;17(30):3328-40. Review.

PMID:
21919877
8.

Cardiac bone marrow cell therapy: the proof of the pudding remains in the eating.

Janssens SP.

Eur Heart J. 2011 Jul;32(14):1697-700. doi: 10.1093/eurheartj/ehq513. Epub 2011 Jun 2. No abstract available.

PMID:
21642282
9.

Modulating endothelial nitric oxide synthase: a new cardiovascular therapeutic strategy.

Zhang Y, Janssens SP, Wingler K, Schmidt HH, Moens AL.

Am J Physiol Heart Circ Physiol. 2011 Sep;301(3):H634-46. doi: 10.1152/ajpheart.01315.2010. Epub 2011 May 27. Review. Erratum in: Am J Physiol Heart Circ Physiol. 2012 Jul 15;303(2):H241.

10.

Granulocyte colony-stimulating factor in cardiac repair: time for a reappraisal?

Janssens SP.

Eur J Heart Fail. 2010 Oct;12(10):1021-3. doi: 10.1093/eurjhf/hfq153. No abstract available.

11.

Cardioselective nitric oxide synthase 3 gene transfer protects against myocardial reperfusion injury.

Szelid Z, Pokreisz P, Liu X, Vermeersch P, Marsboom G, Gillijns H, Pellens M, Verbeken E, Van de Werf F, Collen D, Janssens SP.

Basic Res Cardiol. 2010 Mar;105(2):169-79. doi: 10.1007/s00395-009-0077-4. Epub 2009 Dec 18.

PMID:
20020305
12.

Ventricular phosphodiesterase-5 expression is increased in patients with advanced heart failure and contributes to adverse ventricular remodeling after myocardial infarction in mice.

Pokreisz P, Vandenwijngaert S, Bito V, Van den Bergh A, Lenaerts I, Busch C, Marsboom G, Gheysens O, Vermeersch P, Biesmans L, Liu X, Gillijns H, Pellens M, Van Lommel A, Buys E, Schoonjans L, Vanhaecke J, Verbeken E, Sipido K, Herijgers P, Bloch KD, Janssens SP.

Circulation. 2009 Jan 27;119(3):408-16. doi: 10.1161/CIRCULATIONAHA.108.822072. Epub 2009 Jan 12.

13.

How old is your heart?

Sipido KR, Janssens SP.

Circ Res. 2007 Aug 17;101(4):323-5. No abstract available.

PMID:
17702975
14.

Disruption of nitric oxide synthase 3 protects against the cardiac injury, dysfunction, and mortality induced by doxorubicin.

Neilan TG, Blake SL, Ichinose F, Raher MJ, Buys ES, Jassal DS, Furutani E, Perez-Sanz TM, Graveline A, Janssens SP, Picard MH, Scherrer-Crosbie M, Bloch KD.

Circulation. 2007 Jul 31;116(5):506-14. Epub 2007 Jul 16.

PMID:
17638931
15.

Applied gene therapy in preclinical models of vascular injury.

Janssens SP.

Curr Atheroscler Rep. 2003 May;5(3):186-90. Review.

PMID:
12667430
16.

Nitric oxide synthase-3 overexpression causes apoptosis and impairs neuronal mitochondrial function: relevance to Alzheimer's-type neurodegeneration.

de la Monte SM, Chiche J, von dem Bussche A, Sanyal S, Lahousse SA, Janssens SP, Bloch KD.

Lab Invest. 2003 Feb;83(2):287-98.

PMID:
12594242
17.

Defining gene transfer before expecting gene therapy: putting the horse before the cart.

Pislaru S, Janssens SP, Gersh BJ, Simari RD.

Circulation. 2002 Jul 30;106(5):631-6. Review. No abstract available.

PMID:
12147548
18.

Percutaneous gene therapy using recombinant adenoviruses encoding human herpes simplex virus thymidine kinase, human PAI-1, and human NOS3 in balloon-injured porcine coronary arteries.

Varenne O, Sinnaeve P, Gillijns H, Iung B, Laurysens V, Meurrens K, Bout B, Valerio D, Collen D, Janssens SP, Gerard RD.

Hum Gene Ther. 2000 Jun 10;11(9):1329-39.

PMID:
10890742
19.

Adenovirus-mediated gene transfer of cGMP-dependent protein kinase increases the sensitivity of cultured vascular smooth muscle cells to the antiproliferative and pro-apoptotic effects of nitric oxide/cGMP.

Chiche JD, Schlutsmeyer SM, Bloch DB, de la Monte SM, Roberts JD Jr, Filippov G, Janssens SP, Rosenzweig A, Bloch KD.

J Biol Chem. 1998 Dec 18;273(51):34263-71.

20.

Local adenovirus-mediated transfer of human endothelial nitric oxide synthase reduces luminal narrowing after coronary angioplasty in pigs.

Varenne O, Pislaru S, Gillijns H, Van Pelt N, Gerard RD, Zoldhelyi P, Van de Werf F, Collen D, Janssens SP.

Circulation. 1998 Sep 1;98(9):919-26.

PMID:
9738648
21.

Adenoviral-mediated transfer of the human endothelial nitric oxide synthase gene reduces acute hypoxic pulmonary vasoconstriction in rats.

Janssens SP, Bloch KD, Nong Z, Gerard RD, Zoldhelyi P, Collen D.

J Clin Invest. 1996 Jul 15;98(2):317-24.

22.

Constitutive endothelial nitric oxide synthase gene expression is regulated during lung development.

Kawai N, Bloch DB, Filippov G, Rabkina D, Suen HC, Losty PD, Janssens SP, Zapol WM, de la Monte S, Bloch KD.

Am J Physiol. 1995 Apr;268(4 Pt 1):L589-95.

PMID:
7537461
23.

Functional and structural changes with hypoxia in pulmonary circulation of spontaneously hypertensive rats.

Janssens SP, Thompson BT, Spence CR, Hales CA.

J Appl Physiol (1985). 1994 Sep;77(3):1101-7.

PMID:
7836110
24.

Cyclooxygenase and lipoxygenase inhibition by BW-755C reduces acrolein smoke-induced acute lung injury.

Janssens SP, Musto SW, Hutchison WG, Spence C, Witten M, Jung W, Hales CA.

J Appl Physiol (1985). 1994 Aug;77(2):888-95.

PMID:
8002544
25.

Inhibition of hypoxic pulmonary hypertension by heparins of differing in vitro antiproliferative potency.

Thompson BT, Spence CR, Janssens SP, Joseph PM, Hales CA.

Am J Respir Crit Care Med. 1994 Jun;149(6):1512-7.

PMID:
8004307
26.

cAMP regulates soluble guanylate cyclase beta 1-subunit gene expression in RFL-6 rat fetal lung fibroblasts.

Shimouchi A, Janssens SP, Bloch DB, Zapol WM, Bloch KD.

Am J Physiol. 1993 Nov;265(5 Pt 1):L456-61.

PMID:
7694505
27.

Effect of aerosol heparin on the development of hypoxic pulmonary hypertension in the guinea pig.

Spence CR, Thompson BT, Janssens SP, Steigman DM, Hales CA.

Am Rev Respir Dis. 1993 Jul;148(1):241-4.

PMID:
8317807
28.

Chronic hypoxic pulmonary hypertension in the guinea pig: effect of three levels of hypoxia.

Thompson BT, Steigman DM, Spence CL, Janssens SP, Hales CA.

J Appl Physiol (1985). 1993 Feb;74(2):916-21.

PMID:
8458815
29.

Hypothalamic Na+,K(+)-ATPase inhibitor constricts pulmonary arteries of spontaneously hypertensive rats.

Janssens SP, Kachoris C, Parker WL, Hales CA, Haupert GT Jr.

J Cardiovasc Pharmacol. 1993;22 Suppl 2:S42-6.

PMID:
7508026
30.

Cloning and expression of a cDNA encoding human endothelium-derived relating factor/nitric oxide synthase.

Janssens SP, Simouchi A, Quertermous T, Bloch DB, Bloch KD.

J Biol Chem. 1992 Nov 5;267(31):22694. No abstract available.

PMID:
1385404
31.

Cloning and expression of a cDNA encoding human endothelium-derived relaxing factor/nitric oxide synthase.

Janssens SP, Shimouchi A, Quertermous T, Bloch DB, Bloch KD.

J Biol Chem. 1992 Jul 25;267(21):14519-22. Erratum in: J Biol Chem. 1992 Nov 5;267(31):22694.

32.

Polycythemia and vascular remodeling in chronic hypoxic pulmonary hypertension in guinea pigs.

Janssens SP, Thompson BT, Spence CR, Hales CA.

J Appl Physiol (1985). 1991 Dec;71(6):2218-23.

PMID:
1778916

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