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Items: 1 to 50 of 151

1.

Generation of an induced pluripotent stem cell line (MHHi018-A) from a patient with Cystic Fibrosis carrying p.Asn1303Lys (N1303K) mutation.

Merkert S, Schubert M, Haase A, Janssens HM, Scholte B, Lachmann N, Göhring G, Martin U.

Stem Cell Res. 2020 Mar 25;44:101744. doi: 10.1016/j.scr.2020.101744. [Epub ahead of print]

2.

Incidence, risk factors and re-exacerbation rate of severe asthma exacerbations in a multinational, multidatabase pediatric cohort study.

Engelkes M, Baan EJ, de Ridder MAJ, Svensson E, Prieto-Alhambra D, Lapi F, Giaquinto C, Picelli G, Boudiaf N, Albers F, Evitt LA, Cockle S, Bradford E, Van Dyke MK, Suruki R, Rijnbeek P, Sturkenboom MCJM, Janssens HM, Verhamme KMC.

Pediatr Allergy Immunol. 2020 Mar 1. doi: 10.1111/pai.13237. [Epub ahead of print]

PMID:
32115766
3.

CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank.

Geurts MH, de Poel E, Amatngalim GD, Oka R, Meijers FM, Kruisselbrink E, van Mourik P, Berkers G, de Winter-de Groot KM, Michel S, Muilwijk D, Aalbers BL, Mullenders J, Boj SF, Suen SWF, Brunsveld JE, Janssens HM, Mall MA, Graeber SY, van Boxtel R, van der Ent CK, Beekman JM, Clevers H.

Cell Stem Cell. 2020 Apr 2;26(4):503-510.e7. doi: 10.1016/j.stem.2020.01.019. Epub 2020 Feb 20.

PMID:
32084388
4.

R117H-CFTR function and response to VX-770 correlate with mRNA and protein expression in intestinal organoids.

Van Mourik P, van Haaren P, Kruisselbrink E, Korkmaz C, Janssens HM, de Winter-de Groot KM, van der Ent CK, Hagemeijer MC, Beekman JM.

J Cyst Fibros. 2020 Feb 12. pii: S1569-1993(20)30046-1. doi: 10.1016/j.jcf.2020.02.001. [Epub ahead of print]

PMID:
32061518
5.

Airway profile of bioactive lipids predicts early progression of lung disease in cystic fibrosis.

Horati H, Janssens HM, Margaroli C, Veltman M, Stolarczyk M, Kilgore MB, Chou J, Peng L, Tiddens HAMW, Chandler JD, Tirouvanziam R, Scholte BJ.

J Cyst Fibros. 2020 Feb 10. pii: S1569-1993(20)30034-5. doi: 10.1016/j.jcf.2020.01.010. [Epub ahead of print]

PMID:
32057679
6.

Hair cortisol and inhaled corticosteroid use in asthmatic children.

Baan EJ, van den Akker ELT, Engelkes M, de Rijke YB, de Jongste JC, Sturkenboom MCJM, Verhamme KM, Janssens HM.

Pediatr Pulmonol. 2020 Feb;55(2):316-321. doi: 10.1002/ppul.24551. Epub 2019 Oct 25.

7.

Exploratory Study of Signals for Asthma Drugs in Children, Using the EudraVigilance Database of Spontaneous Reports.

Baan EJ, de Smet VA, Hoeve CE, Pacurariu AC, Sturkenboom MCJM, de Jongste JC, Janssens HM, Verhamme KMC.

Drug Saf. 2020 Jan;43(1):7-16. doi: 10.1007/s40264-019-00870-x.

8.

Airway disease on chest computed tomography of preschool children with cystic fibrosis is associated with school-age bronchiectasis.

Bouma NR, Janssens HM, Andrinopoulou ER, Tiddens HAWM.

Pediatr Pulmonol. 2020 Jan;55(1):141-148. doi: 10.1002/ppul.24498. Epub 2019 Sep 9.

9.

Controlled evaluation of a transition clinic for Dutch young people with cystic fibrosis.

Peeters MAC, Sattoe JNT, van Staa A, Versteeg SE, Heeres I, Rutjes NW, Janssens HM.

Pediatr Pulmonol. 2019 Nov;54(11):1811-1820. doi: 10.1002/ppul.24476. Epub 2019 Aug 19.

10.

Assessing physiological response mechanisms and the role of psychosocial job resources in the physical activity health paradox: study protocol for the Flemish Employees' Physical Activity (FEPA) study.

Ketels M, De Bacquer D, Geens T, Janssens H, Korshøj M, Holtermann A, Clays E.

BMC Public Health. 2019 Jun 15;19(1):765. doi: 10.1186/s12889-019-6950-7.

11.

2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout.

Richette P, Doherty M, Pascual E, Barskova V, Becce F, Castaneda J, Coyfish M, Guillo S, Jansen T, Janssens H, Lioté F, Mallen CD, Nuki G, Perez-Ruiz F, Pimentao J, Punzi L, Pywell A, So AK, Tausche AK, Uhlig T, Zavada J, Zhang W, Tubach F, Bardin T.

Ann Rheum Dis. 2020 Jan;79(1):31-38. doi: 10.1136/annrheumdis-2019-215315. Epub 2019 Jun 5.

PMID:
31167758
12.

Pharmacokinetics and safety of tobramycin nebulization with the I-neb and PARI-LC Plus in children with cystic fibrosis: A randomized, crossover study.

van Velzen AJ, Uges JWF, Heijerman HGM, Arets BGM, Nuijsink M, van der Wiel-Kooij EC, van Maarseveen EM, van Zanten GA, Pullens B, Touw DJ, Janssens HM.

Br J Clin Pharmacol. 2019 Sep;85(9):1984-1993. doi: 10.1111/bcp.13988. Epub 2019 Jul 10.

13.

Oxidative stress and abnormal bioactive lipids in early cystic fibrosis lung disease.

Scholte BJ, Horati H, Veltman M, Vreeken RJ, Garratt LW, Tiddens HAWM, Janssens HM, Stick SM; Australian Respiratory Early Surveillance Team for Cystic Fibrosis (AREST CF).

J Cyst Fibros. 2019 Nov;18(6):781-789. doi: 10.1016/j.jcf.2019.04.011. Epub 2019 Apr 26.

PMID:
31031161
14.

Basal and Evoked Neurotransmitter Levels in Parkin, DJ-1, PINK1 and LRRK2 Knockout Rat Striatum.

Creed RB, Menalled L, Casey B, Dave KD, Janssens HB, Veinbergs I, van der Hart M, Rassoulpour A, Goldberg MS.

Neuroscience. 2019 Jun 15;409:169-179. doi: 10.1016/j.neuroscience.2019.04.033. Epub 2019 Apr 25.

15.

Crystal-proven gout patients have an increased mortality due to cardiovascular diseases, cancer, and infectious diseases especially when having tophi and/or high serum uric acid levels: a prospective cohort study.

Disveld IJM, Zoakman S, Jansen TLTA, Rongen GA, Kienhorst LBE, Janssens HJEM, Fransen J, Janssen M.

Clin Rheumatol. 2019 May;38(5):1385-1391. doi: 10.1007/s10067-019-04520-6. Epub 2019 Mar 30.

PMID:
30929152
16.

Rectal Organoids Enable Personalized Treatment of Cystic Fibrosis.

Berkers G, van Mourik P, Vonk AM, Kruisselbrink E, Dekkers JF, de Winter-de Groot KM, Arets HGM, Marck-van der Wilt REP, Dijkema JS, Vanderschuren MM, Houwen RHJ, Heijerman HGM, van de Graaf EA, Elias SG, Majoor CJ, Koppelman GH, Roukema J, Bakker M, Janssens HM, van der Meer R, Vries RGJ, Clevers HC, de Jonge HR, Beekman JM, van der Ent CK.

Cell Rep. 2019 Feb 12;26(7):1701-1708.e3. doi: 10.1016/j.celrep.2019.01.068.

17.

Antibiotic use in children with asthma: cohort study in UK and Dutch primary care databases.

Baan EJ, Janssens HM, Kerckaert T, Bindels PJE, de Jongste JC, Sturkenboom MCJM, Verhamme KMC.

BMJ Open. 2018 Nov 28;8(11):e022979. doi: 10.1136/bmjopen-2018-022979.

18.

Patient-reported gout attack frequency and allopurinol use in general practice in the Netherlands: a prospective observational cohort study protocol.

van Leeuwen KDB, Bohnen AM, Jacobs ML, van Der Lei J, Janssens HJEM, Koffeman AR, Bindels PJE, Bierma-Zeinstra SMA.

BMJ Open. 2018 Nov 25;8(11):e024335. doi: 10.1136/bmjopen-2018-024335.

19.

COMFFETI, Combined Fresh and Frozen Embryo Transfers per Individual: A New Index of Quality Control for The Performance of emberyologic Labs in The Emerging Era of Segmentation of Cycle and Freeze-All Strategy.

Papanikolaou EG, Timotheou E, Tatsi P, Janssens H, Grynberg M, Athanasiadis A, Zafeirati C, Najdecki R, Petousis S.

Int J Fertil Steril. 2019 Jan;12(4):339-342. doi: 10.22074/ijfs.2019.5424. Epub 2018 Oct 2.

20.

Elastase Exocytosis by Airway Neutrophils Is Associated with Early Lung Damage in Children with Cystic Fibrosis.

Margaroli C, Garratt LW, Horati H, Dittrich AS, Rosenow T, Montgomery ST, Frey DL, Brown MR, Schultz C, Guglani L, Kicic A, Peng L, Scholte BJ, Mall MA, Janssens HM, Stick SM, Tirouvanziam R.

Am J Respir Crit Care Med. 2019 Apr 1;199(7):873-881. doi: 10.1164/rccm.201803-0442OC.

21.

Do Personality Traits Determine Work Engagement? Results From a Belgian Study.

Janssens H, De Zutter P, Geens T, Vogt G, Braeckman L.

J Occup Environ Med. 2019 Jan;61(1):29-34. doi: 10.1097/JOM.0000000000001458.

PMID:
30256301
22.

Myeloperoxidase oxidation of methionine associates with early cystic fibrosis lung disease.

Chandler JD, Margaroli C, Horati H, Kilgore MB, Veltman M, Liu HK, Taurone AJ, Peng L, Guglani L, Uppal K, Go YM, Tiddens HAWM, Scholte BJ, Tirouvanziam R, Jones DP, Janssens HM.

Eur Respir J. 2018 Oct 10;52(4). pii: 1801118. doi: 10.1183/13993003.01118-2018. Print 2018 Oct.

23.

Stratifying infants with cystic fibrosis for disease severity using intestinal organoid swelling as a biomarker of CFTR function.

de Winter-de Groot KM, Janssens HM, van Uum RT, Dekkers JF, Berkers G, Vonk A, Kruisselbrink E, Oppelaar H, Vries R, Clevers H, Houwen RHJ, Escher JC, Elias SG, de Jonge HR, de Rijke YB, Tiddens HAWM, van der Ent CK, Beekman JM.

Eur Respir J. 2018 Sep 17;52(3). pii: 1702529. doi: 10.1183/13993003.02529-2017. Print 2018 Sep.

24.

Newborn blood spot screening for cystic fibrosis with a four-step screening strategy in the Netherlands.

Dankert-Roelse JE, Bouva MJ, Jakobs BS, Janssens HM, de Winter-de Groot KM, Schönbeck Y, Gille JJP, Gulmans VAM, Verschoof-Puite RK, Schielen PCJI, Verkerk PH.

J Cyst Fibros. 2019 Jan;18(1):54-63. doi: 10.1016/j.jcf.2018.07.008. Epub 2018 Aug 23.

PMID:
30146269
25.

Determination of thiocyanate in exhaled breath condensate.

Chandler JD, Horati H, Walker DI, Pagliano E, Tirouvanziam R, Veltman M, Scholte BJ, Janssens HM, Go YM, Jones DP.

Free Radic Biol Med. 2018 Oct;126:334-340. doi: 10.1016/j.freeradbiomed.2018.08.012. Epub 2018 Aug 22.

26.

The relation between social capital and burnout: a longitudinal study.

Janssens H, Braeckman L, Vlerick P, Van de Ven B, De Clercq B, Clays E.

Int Arch Occup Environ Health. 2018 Nov;91(8):1001-1009. doi: 10.1007/s00420-018-1341-4. Epub 2018 Jul 17.

PMID:
30019175
27.

Ocular Neuromyotonia: Case Reports and Literature Review.

Stockman AC, Dieltiëns M, Janssens H, Van Lammeren M, Beelen L, Van Bellinghen V, Cassiman C.

Strabismus. 2018 Sep;26(3):133-141. doi: 10.1080/09273972.2018.1467469. Epub 2018 Apr 25. Review.

PMID:
29693497
28.

Crystal-proven Gout and Characteristic Gout Severity Factors Are Associated with Cardiovascular Disease.

Disveld IJM, Fransen J, Rongen GA, Kienhorst LBE, Zoakman S, Janssens HJEM, Janssen M.

J Rheumatol. 2018 Jun;45(6):858-863. doi: 10.3899/jrheum.170555. Epub 2018 Apr 15.

PMID:
29657151
29.

Comparison of ex vivo and in vitro intestinal cystic fibrosis models to measure CFTR-dependent ion channel activity.

Zomer-van Ommen DD, de Poel E, Kruisselbrink E, Oppelaar H, Vonk AM, Janssens HM, van der Ent CK, Hagemeijer MC, Beekman JM.

J Cyst Fibros. 2018 May;17(3):316-324. doi: 10.1016/j.jcf.2018.02.007. Epub 2018 Mar 13.

PMID:
29544685
30.

A damped oscillator imposes temporal order on posterior gap gene expression in Drosophila.

Verd B, Clark E, Wotton KR, Janssens H, Jiménez-Guri E, Crombach A, Jaeger J.

PLoS Biol. 2018 Feb 16;16(2):e2003174. doi: 10.1371/journal.pbio.2003174. eCollection 2018 Feb.

31.

Brand and generic use of inhalation medication and frequency of switching in children and adults: A population-based cohort study.

Engelkes M, van Blijderveen JC, Overbeek JA, Kuiper J, Herings RCM, Sturkenboom MCJM, de Jongste JC, Verhamme KMC, Janssens HM.

J Asthma. 2018 Oct;55(10):1086-1094. doi: 10.1080/02770903.2017.1396468. Epub 2017 Nov 29.

PMID:
29185812
32.

Patient-specific modelling of regional tobramycin concentration levels in airways of patients with cystic fibrosis: can we dose once daily?

Bos AC, Mouton JW, van Westreenen M, Andrinopoulou ER, Janssens HM, Tiddens HAWM.

J Antimicrob Chemother. 2017 Dec 1;72(12):3435-3442. doi: 10.1093/jac/dkx293.

PMID:
29029057
33.

Performance of the 2015 ACR-EULAR classification criteria for gout in a primary care population presenting with monoarthritis.

Janssens HJEM, Fransen J, Janssen M, Neogi T, Schumacher HR, Jansen TL, Dalbeth N, Taylor WJ.

Rheumatology (Oxford). 2017 Aug 1;56(8):1335-1341. doi: 10.1093/rheumatology/kex164.

PMID:
28431109
34.

Concordance between upper and lower airway microbiota in infants with cystic fibrosis.

Prevaes SM, de Steenhuijsen Piters WA, de Winter-de Groot KM, Janssens HM, Tramper-Stranders GA, Chu ML, Tiddens HA, van Westreenen M, van der Ent CK, Sanders EA, Bogaert D.

Eur Respir J. 2017 Mar 29;49(3). pii: 1602235. doi: 10.1183/13993003.02235-2016. Print 2017 Mar.

35.

The fate of inhaled antibiotics after deposition in cystic fibrosis: How to get drug to the bug?

Bos AC, Passé KM, Mouton JW, Janssens HM, Tiddens HA.

J Cyst Fibros. 2017 Jan;16(1):13-23. doi: 10.1016/j.jcf.2016.10.001. Epub 2016 Oct 26. Review.

36.

Awareness, Knowledge, and Practices Regarding Occupational Hazards Among Medical Students: A Longitudinal Study Before and After Admission as Trainees.

Braeckman L, Verbrugghe M, Janssens H, Verpraet R, Cobbaut L.

J Occup Environ Med. 2017 Apr;59(4):e41-e45. doi: 10.1097/JOM.0000000000000972.

PMID:
28252458
37.

Relationship between non-standard work arrangements and work-related accident absence in Belgium.

Alali H, Braeckman L, Van Hecke T, De Clercq B, Janssens H, Wahab MA.

J Occup Health. 2017 Mar 28;59(2):177-186. doi: 10.1539/joh.16-0119-OA. Epub 2017 Jan 21. Erratum in: J Occup Health. 2017;59(3):e2.

38.

A pilot study of CXCL8 levels in crystal proven gout patients during allopurinol treatment and their association with cardiovascular disease.

Kienhorst L, Janssens H, Radstake T, van Riel P, Jacobs J, van Koolwijk E, van Lochem E, Janssen M.

Joint Bone Spine. 2017 Dec;84(6):709-713. doi: 10.1016/j.jbspin.2016.10.013. Epub 2016 Nov 25.

PMID:
27894951
39.

The relation between indicators of low employment quality and attendance behavior in countries of the European Union.

Janssens H, Braeckman L, De Clercq B, De Bacquer D, Clays E.

J Public Health (Oxf). 2017 Dec 1;39(4):e127-e133. doi: 10.1093/pubmed/fdw112.

PMID:
27744375
40.

Real life data on incidence and risk factors of severe asthma exacerbations in children in primary care.

Engelkes M, Janssens HM, de Ridder MA, Sturkenboom MC, de Jongste JC, Verhamme KM.

Respir Med. 2016 Oct;119:48-54. doi: 10.1016/j.rmed.2016.08.016. Epub 2016 Aug 23.

41.

The indirect association of job strain with long-term sickness absence through bullying: a mediation analysis using structural equation modeling.

Janssens H, Braeckman L, De Clercq B, Casini A, De Bacquer D, Kittel F, Clays E.

BMC Public Health. 2016 Aug 22;16(1):851. doi: 10.1186/s12889-016-3522-y.

42.

Hair cortisol in relation to job stress and depressive symptoms.

Janssens H, Clays E, Fiers T, Verstraete AG, de Bacquer D, Braeckman L.

Occup Med (Lond). 2017 Mar 1;67(2):114-120. doi: 10.1093/occmed/kqw114.

PMID:
27515972
43.

β2-Adrenergic receptor agonists activate CFTR in intestinal organoids and subjects with cystic fibrosis.

Vijftigschild LA, Berkers G, Dekkers JF, Zomer-van Ommen DD, Matthes E, Kruisselbrink E, Vonk A, Hensen CE, Heida-Michel S, Geerdink M, Janssens HM, van de Graaf EA, Bronsveld I, de Winter-de Groot KM, Majoor CJ, Heijerman HG, de Jonge HR, Hanrahan JW, van der Ent CK, Beekman JM.

Eur Respir J. 2016 Sep;48(3):768-79. doi: 10.1183/13993003.01661-2015. Epub 2016 Jul 28.

44.

2016 updated EULAR evidence-based recommendations for the management of gout.

Richette P, Doherty M, Pascual E, Barskova V, Becce F, Castañeda-Sanabria J, Coyfish M, Guillo S, Jansen TL, Janssens H, Lioté F, Mallen C, Nuki G, Perez-Ruiz F, Pimentao J, Punzi L, Pywell T, So A, Tausche AK, Uhlig T, Zavada J, Zhang W, Tubach F, Bardin T.

Ann Rheum Dis. 2017 Jan;76(1):29-42. doi: 10.1136/annrheumdis-2016-209707. Epub 2016 Jul 25. Review.

PMID:
27457514
45.

Functional Characterization of Cholera Toxin Inhibitors Using Human Intestinal Organoids.

Zomer-van Ommen DD, Pukin AV, Fu O, Quarles van Ufford LH, Janssens HM, Beekman JM, Pieters RJ.

J Med Chem. 2016 Jul 28;59(14):6968-72. doi: 10.1021/acs.jmedchem.6b00770. Epub 2016 Jul 7.

PMID:
27347611
46.

Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis.

Dekkers JF, Berkers G, Kruisselbrink E, Vonk A, de Jonge HR, Janssens HM, Bronsveld I, van de Graaf EA, Nieuwenhuis EE, Houwen RH, Vleggaar FP, Escher JC, de Rijke YB, Majoor CJ, Heijerman HG, de Winter-de Groot KM, Clevers H, van der Ent CK, Beekman JM.

Sci Transl Med. 2016 Jun 22;8(344):344ra84. doi: 10.1126/scitranslmed.aad8278.

PMID:
27334259
47.

Gout and rheumatoid arthritis, both to keep in mind in cardiovascular risk management: A primary care retrospective cohort study.

Janssens HJ, Arts PG, Schalk BW, Biermans MC.

Joint Bone Spine. 2017 Jan;84(1):59-64. doi: 10.1016/j.jbspin.2015.12.003. Epub 2016 May 25.

PMID:
27236260
48.

e-Monitoring of Asthma Therapy to Improve Compliance in children (e-MATIC): a randomised controlled trial.

Vasbinder EC, Goossens LM, Rutten-van Mölken MP, de Winter BC, van Dijk L, Vulto AG, Blankman EI, Dahhan N, Veenstra-van Schie MT, Versteegh FG, Wolf BH, Janssens HM, van den Bemt PM.

Eur Respir J. 2016 Sep;48(3):758-67. doi: 10.1183/13993003.01698-2015. Epub 2016 May 26.

49.

Potentiator synergy in rectal organoids carrying S1251N, G551D, or F508del CFTR mutations.

Dekkers JF, Van Mourik P, Vonk AM, Kruisselbrink E, Berkers G, de Winter-de Groot KM, Janssens HM, Bronsveld I, van der Ent CK, de Jonge HR, Beekman JM.

J Cyst Fibros. 2016 Sep;15(5):568-78. doi: 10.1016/j.jcf.2016.04.007. Epub 2016 May 5.

50.

Optimal correction of distinct CFTR folding mutants in rectal cystic fibrosis organoids.

Dekkers JF, Gogorza Gondra RA, Kruisselbrink E, Vonk AM, Janssens HM, de Winter-de Groot KM, van der Ent CK, Beekman JM.

Eur Respir J. 2016 Aug;48(2):451-8. doi: 10.1183/13993003.01192-2015. Epub 2016 Apr 21.

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