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Items: 1 to 50 of 130

1.

Increased Incidence of Colon Tumors in AOM-Treated Apc 1638N/+ Mice Reveals Higher Frequency of Tumor Associated Neutrophils in Colon Than Small Intestine.

Metzger R, Maruskova M, Krebs S, Janssen KP, Krug AB.

Front Oncol. 2019 Oct 2;9:1001. doi: 10.3389/fonc.2019.01001. eCollection 2019.

2.

Two Isoforms of the Guanine Nucleotide Exchange Factor, Daple/CCDC88C Cooperate as Tumor Suppressors.

Ear J, Dunkel Y, Mittal Y, Lim BBC, Liu L, Holda MK, Nitsche U, Barbazán J, Goel A, Janssen KP, Aznar N, Ghosh P.

Sci Rep. 2019 Aug 20;9(1):12124. doi: 10.1038/s41598-019-48420-w.

3.

Thermal unequilibrium of strained black CsPbI3 thin films.

Steele JA, Jin H, Dovgaliuk I, Berger RF, Braeckevelt T, Yuan H, Martin C, Solano E, Lejaeghere K, Rogge SMJ, Notebaert C, Vandezande W, Janssen KPF, Goderis B, Debroye E, Wang YK, Dong Y, Ma D, Saidaminov M, Tan H, Lu Z, Dyadkin V, Chernyshov D, Van Speybroeck V, Sargent EH, Hofkens J, Roeffaers MBJ.

Science. 2019 Aug 16;365(6454):679-684. doi: 10.1126/science.aax3878. Epub 2019 Jul 25.

PMID:
31346140
4.

BarrettNET-a prospective registry for risk estimation of patients with Barrett's esophagus to progress to adenocarcinoma.

Wiethaler M, Slotta-Huspenina J, Brandtner A, Horstmann J, Wein F, Baumeister T, Radani N, Gerland S, Anand A, Lange S, Schmidt M, Janssen KP, Conrad A, Johannes W, Strauch K, Quante AS, Linkohr B, Kuhn KA, Blaser R, Lehmann A, Kohlmayer F, Weichert W, Schmid RM, Becker KF, Quante M.

Dis Esophagus. 2019 Aug 1;32(8). pii: doz024. doi: 10.1093/dote/doz024.

PMID:
31329831
5.

A Blood-Based Multi Marker Assay Supports the Differential Diagnosis of Early-Stage Pancreatic Cancer.

Berger AW, Schwerdel D, Reinacher-Schick A, Uhl W, Algül H, Friess H, Janssen KP, König A, Ghadimi M, Gallmeier E, Bartsch DK, Geissler M, Staib L, Tannapfel A, Kleger A, Beutel A, Schulte LA, Kornmann M, Ettrich TJ, Seufferlein T.

Theranostics. 2019 Feb 12;9(5):1280-1287. doi: 10.7150/thno.29247. eCollection 2019.

6.

The 2018 correlative microscopy techniques roadmap.

Ando T, Bhamidimarri SP, Brending N, Colin-York H, Collinson L, De Jonge N, de Pablo PJ, Debroye E, Eggeling C, Franck C, Fritzsche M, Gerritsen H, Giepmans BNG, Grunewald K, Hofkens J, Hoogenboom JP, Janssen KPF, Kaufman R, Klumpermann J, Kurniawan N, Kusch J, Liv N, Parekh V, Peckys DB, Rehfeldt F, Reutens DC, Roeffaers MBJ, Salditt T, Schaap IAT, Schwarz US, Verkade P, Vogel MW, Wagner R, Winterhalter M, Yuan H, Zifarelli G.

J Phys D Appl Phys. 2018 Nov 7;51(44):443001. doi: 10.1088/1361-6463/aad055. Epub 2018 Aug 31. Review.

7.

The Tumor Suppressor SASH1 Interacts With the Signal Adaptor CRKL to Inhibit Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer.

Franke FC, Müller J, Abal M, Medina ED, Nitsche U, Weidmann H, Chardonnet S, Ninio E, Janssen KP.

Cell Mol Gastroenterol Hepatol. 2018 Sep 11;7(1):33-53. doi: 10.1016/j.jcmgh.2018.08.007. eCollection 2019.

8.

Genetic and immunological biomarkers predict metastatic disease recurrence in stage III colon cancer.

Sperlich A, Balmert A, Doll D, Bauer S, Franke F, Keller G, Wilhelm D, Mur A, Respondek M, Friess H, Nitsche U, Janssen KP.

BMC Cancer. 2018 Oct 19;18(1):998. doi: 10.1186/s12885-018-4940-2.

9.

Cell-type specific MyD88 signaling is required for intestinal tumor initiation and progression to malignancy.

Holtorf A, Conrad A, Holzmann B, Janssen KP.

Oncoimmunology. 2018 Jun 11;7(8):e1466770. doi: 10.1080/2162402X.2018.1466770. eCollection 2018.

10.

Activated ATF6 Induces Intestinal Dysbiosis and Innate Immune Response to Promote Colorectal Tumorigenesis.

Coleman OI, Lobner EM, Bierwirth S, Sorbie A, Waldschmitt N, Rath E, Berger E, Lagkouvardos I, Clavel T, McCoy KD, Weber A, Heikenwalder M, Janssen KP, Haller D.

Gastroenterology. 2018 Nov;155(5):1539-1552.e12. doi: 10.1053/j.gastro.2018.07.028. Epub 2018 Jul 29. Erratum in: Gastroenterology. 2018 Dec;155(6):2027.

11.

The Oncolytic Adenovirus XVir-N-31 as a Novel Therapy in Muscle-Invasive Bladder Cancer.

Lichtenegger E, Koll F, Haas H, Mantwill K, Janssen KP, Laschinger M, Gschwend J, Steiger K, Black PC, Moskalev I, Nawroth R, Holm PS.

Hum Gene Ther. 2019 Jan;30(1):44-56. doi: 10.1089/hum.2018.026. Epub 2018 Aug 3.

PMID:
29916265
12.

PPARγ-activation increases intestinal M1 macrophages and mitigates formation of serrated adenomas in mutant KRAS mice.

Gutting T, Weber CA, Weidner P, Herweck F, Henn S, Friedrich T, Yin S, Kzhyshkowska J, Gaiser T, Janssen KP, Reindl W, Ebert MPA, Burgermeister E.

Oncoimmunology. 2018 Feb 1;7(5):e1423168. doi: 10.1080/2162402X.2017.1423168. eCollection 2018.

13.

Imaging Heterogeneously Distributed Photo-Active Traps in Perovskite Single Crystals.

Yuan H, Debroye E, Bladt E, Lu G, Keshavarz M, Janssen KPF, Roeffaers MBJ, Bals S, Sargent EH, Hofkens J.

Adv Mater. 2018 Mar;30(13):e1705494. doi: 10.1002/adma.201705494. Epub 2018 Feb 19.

PMID:
29457290
14.

Gut microbiota modulate T cell trafficking into human colorectal cancer.

Cremonesi E, Governa V, Garzon JFG, Mele V, Amicarella F, Muraro MG, Trella E, Galati-Fournier V, Oertli D, Däster SR, Droeser RA, Weixler B, Bolli M, Rosso R, Nitsche U, Khanna N, Egli A, Keck S, Slotta-Huspenina J, Terracciano LM, Zajac P, Spagnoli GC, Eppenberger-Castori S, Janssen KP, Borsig L, Iezzi G.

Gut. 2018 Nov;67(11):1984-1994. doi: 10.1136/gutjnl-2016-313498. Epub 2018 Feb 6.

PMID:
29437871
15.

An introduction to optical super-resolution microscopy for the adventurous biologist.

Vangindertael J, Camacho R, Sempels W, Mizuno H, Dedecker P, Janssen KPF.

Methods Appl Fluoresc. 2018 Mar 16;6(2):022003. doi: 10.1088/2050-6120/aaae0c. Review.

PMID:
29422456
16.

Interferon-inducible CXC-chemokines are crucial immune modulators and survival predictors in colorectal cancer.

Kistner L, Doll D, Holtorf A, Nitsche U, Janssen KP.

Oncotarget. 2017 Sep 28;8(52):89998-90012. doi: 10.18632/oncotarget.21286. eCollection 2017 Oct 27.

17.

Cancer cells induce interleukin-22 production from memory CD4+ T cells via interleukin-1 to promote tumor growth.

Voigt C, May P, Gottschlich A, Markota A, Wenk D, Gerlach I, Voigt S, Stathopoulos GT, Arendt KAM, Heise C, Rataj F, Janssen KP, Königshoff M, Winter H, Himsl I, Thasler WE, Schnurr M, Rothenfußer S, Endres S, Kobold S.

Proc Natl Acad Sci U S A. 2017 Dec 5;114(49):12994-12999. doi: 10.1073/pnas.1705165114. Epub 2017 Nov 17.

18.

Targeting myeloid derived suppressor cells with all-trans retinoic acid is highly time-dependent in therapeutic tumor vaccination.

Heine A, Flores C, Gevensleben H, Diehl L, Heikenwalder M, Ringelhan M, Janssen KP, Nitsche U, Garbi N, Brossart P, Knolle PA, Kurts C, Höchst B.

Oncoimmunology. 2017 Jun 16;6(8):e1338995. doi: 10.1080/2162402X.2017.1338995. eCollection 2017.

19.

Highly controllable direct femtosecond laser writing of gold nanostructures on titanium dioxide surfaces.

Fujita Y, Aubert R, Walke P, Yuan H, Kenens B, Inose T, Steuwe C, Toyouchi S, Fortuni B, Chamtouri M, Janssen KPF, De Feyter S, Roeffaers MBJ, Uji-I H.

Nanoscale. 2017 Sep 14;9(35):13025-13033. doi: 10.1039/c7nr04299j.

PMID:
28832041
20.

Rationalizing Acid Zeolite Performance on the Nanoscale by Correlative Fluorescence and Electron Microscopy.

Van Loon J, Janssen KPF, Franklin T, Kubarev AV, Steele JA, Debroye E, Breynaert E, Martens JA, Roeffaers MBJ.

ACS Catal. 2017 Aug 4;7(8):5234-5242. doi: 10.1021/acscatal.7b01148. Epub 2017 Jun 22.

21.

Parts per Million Detection of Alcohol Vapors via Metal Organic Framework Functionalized Surface Plasmon Resonance Sensors.

Vandezande W, Janssen KPF, Delport F, Ameloot R, De Vos DE, Lammertyn J, Roeffaers MBJ.

Anal Chem. 2017 Apr 18;89(8):4480-4487. doi: 10.1021/acs.analchem.6b04510. Epub 2017 Mar 30.

PMID:
28318240
22.

Blood-based detection of RAS mutations to guide anti-EGFR therapy in colorectal cancer patients: concordance of results from circulating tumor DNA and tissue-based RAS testing.

Schmiegel W, Scott RJ, Dooley S, Lewis W, Meldrum CJ, Pockney P, Draganic B, Smith S, Hewitt C, Philimore H, Lucas A, Shi E, Namdarian K, Chan T, Acosta D, Ping-Chang S, Tannapfel A, Reinacher-Schick A, Uhl W, Teschendorf C, Wolters H, Stern J, Viebahn R, Friess H, Janssen KP, Nitsche U, Slotta-Huspenina J, Pohl M, Vangala D, Baraniskin A, Dockhorn-Dworniczak B, Hegewisch-Becker S, Ronga P, Edelstein DL, Jones FS, Hahn S, Fox SB.

Mol Oncol. 2017 Feb;11(2):208-219. doi: 10.1002/1878-0261.12023. Epub 2017 Jan 20.

23.

Facet-Dependent Photoreduction on Single ZnO Crystals.

Debroye E, Van Loon J, Yuan H, Janssen KP, Lou Z, Kim S, Majima T, Roeffaers MB.

J Phys Chem Lett. 2017 Jan 19;8(2):340-346. doi: 10.1021/acs.jpclett.6b02577. Epub 2016 Dec 30.

24.

Methyltransferase-Directed Labeling of Biomolecules and its Applications.

Deen J, Vranken C, Leen V, Neely RK, Janssen KPF, Hofkens J.

Angew Chem Int Ed Engl. 2017 May 2;56(19):5182-5200. doi: 10.1002/anie.201608625. Epub 2017 Apr 10. Review.

25.

Mitochondrial function controls intestinal epithelial stemness and proliferation.

Berger E, Rath E, Yuan D, Waldschmitt N, Khaloian S, Allgäuer M, Staszewski O, Lobner EM, Schöttl T, Giesbertz P, Coleman OI, Prinz M, Weber A, Gerhard M, Klingenspor M, Janssen KP, Heikenwalder M, Haller D.

Nat Commun. 2016 Oct 27;7:13171. doi: 10.1038/ncomms13171.

26.

Photoluminescence Blinking of Single-Crystal Methylammonium Lead Iodide Perovskite Nanorods Induced by Surface Traps.

Yuan H, Debroye E, Caliandro G, Janssen KP, van Loon J, Kirschhock CE, Martens JA, Hofkens J, Roeffaers MB.

ACS Omega. 2016 Jul 31;1(1):148-159. Epub 2016 Jul 26.

27.

Subcellular compartmentalization of docking protein-1 contributes to progression in colorectal cancer.

Friedrich T, Söhn M, Gutting T, Janssen KP, Behrens HM, Röcken C, Ebert MPA, Burgermeister E.

EBioMedicine. 2016 Jun;8:159-172. doi: 10.1016/j.ebiom.2016.05.003. Epub 2016 May 5.

28.

High-mass-resolution MALDI mass spectrometry imaging of metabolites from formalin-fixed paraffin-embedded tissue.

Ly A, Buck A, Balluff B, Sun N, Gorzolka K, Feuchtinger A, Janssen KP, Kuppen PJ, van de Velde CJ, Weirich G, Erlmeier F, Langer R, Aubele M, Zitzelsberger H, McDonnell L, Aichler M, Walch A.

Nat Protoc. 2016 Aug;11(8):1428-43. doi: 10.1038/nprot.2016.081. Epub 2016 Jul 14.

PMID:
27414759
29.

C-C chemokine receptor type-4 transduction of T cells enhances interaction with dendritic cells, tumor infiltration and therapeutic efficacy of adoptive T cell transfer.

Rapp M, Grassmann S, Chaloupka M, Layritz P, Kruger S, Ormanns S, Rataj F, Janssen KP, Endres S, Anz D, Kobold S.

Oncoimmunology. 2015 Oct 29;5(3):e1105428. eCollection 2016 Mar.

30.

A porcine model of osteosarcoma.

Saalfrank A, Janssen KP, Ravon M, Flisikowski K, Eser S, Steiger K, Flisikowska T, Müller-Fliedner P, Schulze É, Brönner C, Gnann A, Kappe E, Böhm B, Schade B, Certa U, Saur D, Esposito I, Kind A, Schnieke A.

Oncogenesis. 2016 Mar 14;5:e210. doi: 10.1038/oncsis.2016.19.

31.

Prognostic Impact of Modulators of G proteins in Circulating Tumor Cells from Patients with Metastatic Colorectal Cancer.

Barbazan J, Dunkel Y, Li H, Nitsche U, Janssen KP, Messer K, Ghosh P.

Sci Rep. 2016 Feb 26;6:22112. doi: 10.1038/srep22112.

32.

Gastric Adenocarcinomas Express the Glycosphingolipid Gb3/CD77: Targeting of Gastric Cancer Cells with Shiga Toxin B-Subunit.

Geyer PE, Maak M, Nitsche U, Perl M, Novotny A, Slotta-Huspenina J, Dransart E, Holtorf A, Johannes L, Janssen KP.

Mol Cancer Ther. 2016 May;15(5):1008-17. doi: 10.1158/1535-7163.MCT-15-0633. Epub 2016 Jan 29.

33.
34.

Resolving Interparticle Heterogeneities in Composition and Hydrogenation Performance between Individual Supported Silver on Silica Catalysts.

Plessers E, Stassen I, Sree SP, Janssen KP, Yuan H, Martens J, Hofkens J, De Vos D, Roeffaers MB.

ACS Catal. 2015 Nov 6;5(11):6690-6695. Epub 2015 Sep 30.

35.

A hypermorphic epithelial β-catenin mutation facilitates intestinal tumorigenesis in mice in response to compounding WNT-pathway mutations.

Buchert M, Rohde F, Eissmann M, Tebbutt N, Williams B, Tan CW, Owen A, Hirokawa Y, Gnann A, Orend G, Orner G, Dashwood RH, Heath JK, Ernst M, Janssen KP.

Dis Model Mech. 2015 Nov;8(11):1361-73. doi: 10.1242/dmm.019844. Epub 2015 Aug 6.

36.

An integrative approach for the identification of prognostic and predictive biomarkers in rectal cancer.

Agostini M, Janssen KP, Kim IJ, D'Angelo E, Pizzini S, Zangrando A, Zanon C, Pastrello C, Maretto I, Digito M, Bedin C, Jurisica I, Rizzolio F, Giordano A, Bortoluzzi S, Nitti D, Pucciarelli S.

Oncotarget. 2015 Oct 20;6(32):32561-74. doi: 10.18632/oncotarget.4935.

37.

The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated β-catenin by sequestering TCF4 to the nuclear membrane.

Loregger A, Grandl M, Mejías-Luque R, Allgäuer M, Degenhart K, Haselmann V, Oikonomou C, Hatzis P, Janssen KP, Nitsche U, Gradl D, van den Broek O, Destree O, Ulm K, Neumaier M, Kalali B, Jung A, Varela I, Schmid RM, Rad R, Busch DH, Gerhard M.

Sci Signal. 2015 Sep 8;8(393):ra90. doi: 10.1126/scisignal.aac6757.

PMID:
26350900
38.

SASH1, a new potential link between smoking and atherosclerosis.

Weidmann H, Touat-Hamici Z, Durand H, Mueller C, Chardonnet S, Pionneau C, Charlotte F, Janssen KP, Verdugo R, Cambien F, Blankenberg S, Tiret L, Zeller T, Ninio E.

Atherosclerosis. 2015 Oct;242(2):571-9. doi: 10.1016/j.atherosclerosis.2015.08.013. Epub 2015 Aug 14.

PMID:
26318107
39.

SASH1 Is Involved in an Autosomal Dominant Lentiginous Phenotype.

Shellman YG, Lambert KA, Brauweiler A, Fain P, Spritz RA, Martini M, Janssen KP, Box NF, Terzian T, Rewers M, Horvath A, Stratakis CA, Robinson WA, Robinson SE, Norris DA, Artinger KB, Pacheco TR.

J Invest Dermatol. 2015 Dec;135(12):3192-3194. doi: 10.1038/jid.2015.292. Epub 2015 Jul 23. No abstract available.

40.

Daple is a novel non-receptor GEF required for trimeric G protein activation in Wnt signaling.

Aznar N, Midde KK, Dunkel Y, Lopez-Sanchez I, Pavlova Y, Marivin A, Barbazán J, Murray F, Nitsche U, Janssen KP, Willert K, Goel A, Abal M, Garcia-Marcos M, Ghosh P.

Elife. 2015 Jun 30;4:e07091. doi: 10.7554/eLife.07091.

41.

High-resolution MALDI-FT-ICR MS imaging for the analysis of metabolites from formalin-fixed, paraffin-embedded clinical tissue samples.

Buck A, Ly A, Balluff B, Sun N, Gorzolka K, Feuchtinger A, Janssen KP, Kuppen PJ, van de Velde CJ, Weirich G, Erlmeier F, Langer R, Aubele M, Zitzelsberger H, Aichler M, Walch A.

J Pathol. 2015 Sep;237(1):123-32. doi: 10.1002/path.4560. Epub 2015 Jun 30.

PMID:
25965788
42.

Outcome after surgery for acute right-sided colonic ischemia without feasible vascular intervention: a single center experience of 58 patients over 6 years.

Käser SA, Müller TC, Guggemos A, Nitsche U, Späth C, Maurer CA, Janssen KP, Kleeff J, Friess H, Wilhelm D, Bader FG.

BMC Surg. 2015 Mar 21;15:31. doi: 10.1186/s12893-015-0018-0.

43.

Spatial organization of the tenascin-C microenvironment in experimental and human cancer.

Spenlé C, Gasser I, Saupe F, Janssen KP, Arnold C, Klein A, van der Heyden M, Mutterer J, Neuville-Méchine A, Chenard MP, Guenot D, Esposito I, Slotta-Huspenina J, Ambartsumian N, Simon-Assmann P, Orend G.

Cell Adh Migr. 2015;9(1-2):4-13. doi: 10.1080/19336918.2015.1005452.

44.

IP-10/CXCL10 induction in human pancreatic cancer stroma influences lymphocytes recruitment and correlates with poor survival.

Lunardi S, Jamieson NB, Lim SY, Griffiths KL, Carvalho-Gaspar M, Al-Assar O, Yameen S, Carter RC, McKay CJ, Spoletini G, D'Ugo S, Silva MA, Sansom OJ, Janssen KP, Muschel RJ, Brunner TB.

Oncotarget. 2014 Nov 30;5(22):11064-80.

45.

MicroRNA classifier and nomogram for metastasis prediction in colon cancer.

Goossens-Beumer IJ, Derr RS, Buermans HP, Goeman JJ, Böhringer S, Morreau H, Nitsche U, Janssen KP, van de Velde CJ, Kuppen PJ.

Cancer Epidemiol Biomarkers Prev. 2015 Jan;24(1):187-97. doi: 10.1158/1055-9965.EPI-14-0544-T. Epub 2014 Oct 14.

46.

Distribution and quantification of irinotecan and its active metabolite SN-38 in colon cancer murine model systems using MALDI MSI.

Buck A, Halbritter S, Späth C, Feuchtinger A, Aichler M, Zitzelsberger H, Janssen KP, Walch A.

Anal Bioanal Chem. 2015 Mar;407(8):2107-16. doi: 10.1007/s00216-014-8237-2. Epub 2014 Oct 14.

PMID:
25311193
47.

Tissue inhibitor of metalloproteinases (TIMP)-1 creates a premetastatic niche in the liver through SDF-1/CXCR4-dependent neutrophil recruitment in mice.

Seubert B, Grünwald B, Kobuch J, Cui H, Schelter F, Schaten S, Siveke JT, Lim NH, Nagase H, Simonavicius N, Heikenwalder M, Reinheckel T, Sleeman JP, Janssen KP, Knolle PA, Krüger A.

Hepatology. 2015 Jan;61(1):238-48. doi: 10.1002/hep.27378. Epub 2014 Nov 24.

48.

Investigation of Schwann cells at neoplastic cell sites before the onset of cancer invasion.

Demir IE, Boldis A, Pfitzinger PL, Teller S, Brunner E, Klose N, Kehl T, Maak M, Lesina M, Laschinger M, Janssen KP, Algül H, Friess H, Ceyhan GO.

J Natl Cancer Inst. 2014 Aug 8;106(8). pii: dju184. doi: 10.1093/jnci/dju184. Print 2014 Aug.

PMID:
25106646
49.

Colorectal cancer surgery remains effective with rising patient age.

Nitsche U, Späth C, Müller TC, Maak M, Janssen KP, Wilhelm D, Kleeff J, Bader FG.

Int J Colorectal Dis. 2014 Aug;29(8):971-9. doi: 10.1007/s00384-014-1914-y. Epub 2014 Jun 13.

50.

Could hyponatremia be a marker of anastomotic leakage after colorectal surgery? A single center analysis of 1,106 patients over 5 years.

Käser SA, Nitsche U, Maak M, Michalski CW, Späth C, Müller TC, Maurer CA, Janssen KP, Kleeff J, Friess H, Bader FG.

Langenbecks Arch Surg. 2014 Aug;399(6):783-8. doi: 10.1007/s00423-014-1213-7. Epub 2014 May 23.

PMID:
24852218

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