Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 98

1.

The direct and sustained consequences of severe placental hypoxia on vascular contractility.

Vangrieken P, Al-Nasiry S, Janssen GMJ, Weseler AR, Spaanderman ME, Bast A, Schiffers PMH.

PLoS One. 2018 Aug 24;13(8):e0202648. doi: 10.1371/journal.pone.0202648. eCollection 2018.

2.

A flexible MHC class I multimer loading system for large-scale detection of antigen-specific T cells.

Luimstra JJ, Garstka MA, Roex MCJ, Redeker A, Janssen GMC, van Veelen PA, Arens R, Falkenburg JHF, Neefjes J, Ovaa H.

J Exp Med. 2018 May 7;215(5):1493-1504. doi: 10.1084/jem.20180156. Epub 2018 Apr 17.

3.

Specific T Cell Responses against Minor Histocompatibility Antigens Cannot Generally Be Explained by Absence of Their Allelic Counterparts on the Cell Surface.

Bijen HM, Hassan C, Kester MGD, Janssen GMC, Hombrink P, de Ru AH, Drijfhout JW, Meiring HD, de Jong AP, Falkenburg JHF, Jimenez CR, Heemskerk MHM, van Veelen PA.

Proteomics. 2018 Jun;18(12):e1700250. doi: 10.1002/pmic.201700250. Epub 2018 Feb 23.

PMID:
29251415
4.

Pitfalls in the detection of citrullination and carbamylation.

Verheul MK, van Veelen PA, van Delft MAM, de Ru A, Janssen GMC, Rispens T, Toes REM, Trouw LA.

Autoimmun Rev. 2018 Feb;17(2):136-141. doi: 10.1016/j.autrev.2017.11.017. Epub 2017 Dec 2. Review.

5.

A Specialist Macaque MHC Class I Molecule with HLA-B*27-like Peptide-Binding Characteristics.

de Groot NG, Heijmans CMC, de Ru AH, Janssen GMC, Drijfhout JW, Otting N, Vangenot C, Doxiadis GGM, Koning F, van Veelen PA, Bontrop RE.

J Immunol. 2017 Nov 15;199(10):3679-3690. doi: 10.4049/jimmunol.1700502. Epub 2017 Oct 11.

PMID:
29021373
6.

Breach of autoreactive B cell tolerance by post-translationally modified proteins.

Dekkers JS, Verheul MK, Stoop JN, Liu B, Ioan-Facsinay A, van Veelen PA, de Ru AH, Janssen GMC, Hegen M, Rapecki S, Huizinga TWJ, Trouw LA, Toes REM.

Ann Rheum Dis. 2017 Aug;76(8):1449-1457. doi: 10.1136/annrheumdis-2016-210772. Epub 2017 Apr 25.

PMID:
28442530
7.

Identification of carbamylated alpha 1 anti-trypsin (A1AT) as an antigenic target of anti-CarP antibodies in patients with rheumatoid arthritis.

Verheul MK, Yee A, Seaman A, Janssen GM, van Veelen PA, Drijfhout JW, Toes REM, Mahler M, Trouw LA.

J Autoimmun. 2017 Jun;80:77-84. doi: 10.1016/j.jaut.2017.02.008. Epub 2017 Mar 11.

PMID:
28291659
8.

Rutin protects against H2O2-triggered impaired relaxation of placental arterioles and induces Nrf2-mediated adaptation in Human Umbilical Vein Endothelial Cells exposed to oxidative stress.

Sthijns MMJPE, Schiffers PM, Janssen GM, Lemmens KJA, Ides B, Vangrieken P, Bouwman FG, Mariman EC, Pader I, Arnér ESJ, Johansson K, Bast A, Haenen GRMM.

Biochim Biophys Acta Gen Subj. 2017 May;1861(5 Pt A):1177-1189. doi: 10.1016/j.bbagen.2017.03.004. Epub 2017 Mar 7.

PMID:
28286015
9.

CD4 T-cell cytokines synergize to induce proliferation of malignant and nonmalignant innate intraepithelial lymphocytes.

Kooy-Winkelaar YM, Bouwer D, Janssen GM, Thompson A, Brugman MH, Schmitz F, de Ru AH, van Gils T, Bouma G, van Rood JJ, van Veelen PA, Mearin ML, Mulder CJ, Koning F, van Bergen J.

Proc Natl Acad Sci U S A. 2017 Feb 7;114(6):E980-E989. doi: 10.1073/pnas.1620036114. Epub 2017 Jan 3.

10.

Tumor Eradication by Cisplatin Is Sustained by CD80/86-Mediated Costimulation of CD8+ T Cells.

Beyranvand Nejad E, van der Sluis TC, van Duikeren S, Yagita H, Janssen GM, van Veelen PA, Melief CJ, van der Burg SH, Arens R.

Cancer Res. 2016 Oct 15;76(20):6017-6029. Epub 2016 Aug 28.

11.

Ectopic miR-125a Expression Induces Long-Term Repopulating Stem Cell Capacity in Mouse and Human Hematopoietic Progenitors.

Wojtowicz EE, Lechman ER, Hermans KG, Schoof EM, Wienholds E, Isserlin R, van Veelen PA, Broekhuis MJ, Janssen GM, Trotman-Grant A, Dobson SM, Krivdova G, Elzinga J, Kennedy J, Gan OI, Sinha A, Ignatchenko V, Kislinger T, Dethmers-Ausema B, Weersing E, Alemdehy MF, de Looper HW, Bader GD, Ritsema M, Erkeland SJ, Bystrykh LV, Dick JE, de Haan G.

Cell Stem Cell. 2016 Sep 1;19(3):383-96. doi: 10.1016/j.stem.2016.06.008. Epub 2016 Jul 14.

12.

An ER-Associated Pathway Defines Endosomal Architecture for Controlled Cargo Transport.

Jongsma ML, Berlin I, Wijdeven RH, Janssen L, Janssen GM, Garstka MA, Janssen H, Mensink M, van Veelen PA, Spaapen RM, Neefjes J.

Cell. 2016 Jun 30;166(1):152-66. doi: 10.1016/j.cell.2016.05.078.

13.

Dendritic Cells Guide Islet Autoimmunity through a Restricted and Uniquely Processed Peptidome Presented by High-Risk HLA-DR.

van Lummel M, van Veelen PA, de Ru AH, Janssen GM, Pool J, Laban S, Joosten AM, Nikolic T, Drijfhout JW, Mearin ML, Aanstoot HJ, Peakman M, Roep BO.

J Immunol. 2016 Apr 15;196(8):3253-63. doi: 10.4049/jimmunol.1501282. Epub 2016 Mar 4.

14.

Phosphodiesterase 1 regulation is a key mechanism in vascular aging.

Bautista Niño PK, Durik M, Danser AH, de Vries R, Musterd-Bhaggoe UM, Meima ME, Kavousi M, Ghanbari M, Hoeijmakers JH, O'Donnell CJ, Franceschini N, Janssen GM, De Mey JG, Liu Y, Shanahan CM, Franco OH, Dehghan A, Roks AJ.

Clin Sci (Lond). 2015 Dec;129(12):1061-75. doi: 10.1042/CS20140753. Epub 2015 Jun 25.

PMID:
26464516
15.

Discovery of an essential nucleotidylating activity associated with a newly delineated conserved domain in the RNA polymerase-containing protein of all nidoviruses.

Lehmann KC, Gulyaeva A, Zevenhoven-Dobbe JC, Janssen GM, Ruben M, Overkleeft HS, van Veelen PA, Samborskiy DV, Kravchenko AA, Leontovich AM, Sidorov IA, Snijder EJ, Posthuma CC, Gorbalenya AE.

Nucleic Acids Res. 2015 Sep 30;43(17):8416-34. doi: 10.1093/nar/gkv838. Epub 2015 Aug 24.

16.

ICL-induced miR139-3p and miR199a-3p have opposite roles in hematopoietic cell expansion and leukemic transformation.

Alemdehy MF, Haanstra JR, de Looper HW, van Strien PM, Verhagen-Oldenampsen J, Caljouw Y, Sanders MA, Hoogenboezem R, de Ru AH, Janssen GM, Smetsers SE, Bierings MB, van Veelen PA, von Lindern M, Touw IP, Erkeland SJ.

Blood. 2015 Jun 18;125(25):3937-48. doi: 10.1182/blood-2014-11-612507. Epub 2015 Mar 16.

17.

The first step of peptide selection in antigen presentation by MHC class I molecules.

Garstka MA, Fish A, Celie PH, Joosten RP, Janssen GM, Berlin I, Hoppes R, Stadnik M, Janssen L, Ovaa H, van Veelen PA, Perrakis A, Neefjes J.

Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):1505-10. doi: 10.1073/pnas.1416543112. Epub 2015 Jan 20.

18.

Extensive glycosylation of ACPA-IgG variable domains modulates binding to citrullinated antigens in rheumatoid arthritis.

Rombouts Y, Willemze A, van Beers JJ, Shi J, Kerkman PF, van Toorn L, Janssen GM, Zaldumbide A, Hoeben RC, Pruijn GJ, Deelder AM, Wolbink G, Rispens T, van Veelen PA, Huizinga TW, Wuhrer M, Trouw LA, Scherer HU, Toes RE.

Ann Rheum Dis. 2016 Mar;75(3):578-85. doi: 10.1136/annrheumdis-2014-206598. Epub 2015 Jan 13.

PMID:
25587188
19.

Accurate quantitation of MHC-bound peptides by application of isotopically labeled peptide MHC complexes.

Hassan C, Kester MG, Oudgenoeg G, de Ru AH, Janssen GM, Drijfhout JW, Spaapen RM, Jiménez CR, Heemskerk MH, Falkenburg JH, van Veelen PA.

J Proteomics. 2014 Sep 23;109:240-4. doi: 10.1016/j.jprot.2014.07.009. Epub 2014 Jul 19.

PMID:
25050860
20.

Carbamylation and antibodies against carbamylated proteins in autoimmunity and other pathologies.

Shi J, van Veelen PA, Mahler M, Janssen GM, Drijfhout JW, Huizinga TW, Toes RE, Trouw LA.

Autoimmun Rev. 2014 Mar;13(3):225-30. doi: 10.1016/j.autrev.2013.10.008. Epub 2013 Oct 28. Review.

PMID:
24176675
21.

Endothelin-1 and endothelin-2 initiate and maintain contractile responses by different mechanisms in rat mesenteric and cerebral arteries.

Compeer MG, Janssen GM, De Mey JG.

Br J Pharmacol. 2013 Nov;170(6):1199-209. doi: 10.1111/bph.12332.

22.

Polyubiquitination and proteasomal turnover controls the anti-apoptotic activity of Bcl-B.

van de Kooij B, Rooswinkel RW, Kok F, Herrebout M, de Vries E, Paauwe M, Janssen GM, van Veelen PA, Borst J.

Oncogene. 2013 Nov 28;32(48):5439-48. doi: 10.1038/onc.2013.99. Epub 2013 Apr 8.

23.

Non-random mtDNA segregation patterns indicate a metastable heteroplasmic segregation unit in m.3243A>G cybrid cells.

Raap AK, Jahangir Tafrechi RS, van de Rijke FM, Pyle A, Wählby C, Szuhai K, Ravelli RB, de Coo RF, Rajasimha HK, Nilsson M, Chinnery PF, Samuels DC, Janssen GM.

PLoS One. 2012;7(12):e52080. doi: 10.1371/journal.pone.0052080. Epub 2012 Dec 18.

24.

Recognition of citrullinated and carbamylated proteins by human antibodies: specificity, cross-reactivity and the 'AMC-Senshu' method.

Shi J, Willemze A, Janssen GM, van Veelen PA, Drijfhout JW, Cerami A, Huizinga TW, Trouw LA, Toes RE.

Ann Rheum Dis. 2013 Jan;72(1):148-50. doi: 10.1136/annrheumdis-2012-201559. Epub 2012 Jul 26. No abstract available.

PMID:
22843489
25.

Type 1 diabetes-associated HLA-DQ8 transdimer accommodates a unique peptide repertoire.

van Lummel M, van Veelen PA, Zaldumbide A, de Ru A, Janssen GM, Moustakas AK, Papadopoulos GK, Drijfhout JW, Roep BO, Koning F.

J Biol Chem. 2012 Mar 16;287(12):9514-24. doi: 10.1074/jbc.M111.313940. Epub 2011 Dec 19.

26.

Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage.

Shi J, Knevel R, Suwannalai P, van der Linden MP, Janssen GM, van Veelen PA, Levarht NE, van der Helm-van Mil AH, Cerami A, Huizinga TW, Toes RE, Trouw LA.

Proc Natl Acad Sci U S A. 2011 Oct 18;108(42):17372-7. doi: 10.1073/pnas.1114465108. Epub 2011 Oct 10.

27.

The redox state of transglutaminase 2 controls arterial remodeling.

van den Akker J, VanBavel E, van Geel R, Matlung HL, Guvenc Tuna B, Janssen GM, van Veelen PA, Boelens WC, De Mey JG, Bakker EN.

PLoS One. 2011;6(8):e23067. doi: 10.1371/journal.pone.0023067. Epub 2011 Aug 25.

28.

Impaired autonomic regulation of resistance arteries in mice with low vascular endothelial growth factor or upon vascular endothelial growth factor trap delivery.

Storkebaum E, Ruiz de Almodovar C, Meens M, Zacchigna S, Mazzone M, Vanhoutte G, Vinckier S, Miskiewicz K, Poesen K, Lambrechts D, Janssen GM, Fazzi GE, Verstreken P, Haigh J, Schiffers PM, Rohrer H, Van der Linden A, De Mey JG, Carmeliet P.

Circulation. 2010 Jul 20;122(3):273-81. doi: 10.1161/CIRCULATIONAHA.109.929364. Epub 2010 Jul 6.

PMID:
20606119
29.

Twenty-four-hour exposure to altered blood flow modifies endothelial Ca2+-activated K+ channels in rat mesenteric arteries.

Hilgers RH, Janssen GM, Fazzi GE, De Mey JG.

J Pharmacol Exp Ther. 2010 Apr;333(1):210-7. doi: 10.1124/jpet.109.161448. Epub 2009 Dec 29.

30.

Calibration of parameter fields consisting of multiple statistical populations.

Janssen GM, Valstar JR.

Ground Water. 2010 Jan-Feb;48(1):92-105. doi: 10.1111/j.1745-6584.2009.00607.x. Epub 2009 Jul 31.

PMID:
19664048
31.

Transient and constitutive repression of cytoplasmic translation signaling in cells with mtDNA mutation.

Janssen GM, Schwertman P, Wanga TA, Tafrechi RS, van den Broek PJ, Raap AK.

Cell Mol Life Sci. 2009 Feb;66(4):721-30. doi: 10.1007/s00018-009-8687-4.

PMID:
19137259
32.

Mechanisms leading to increased vasodilator responses to calcitonin-gene-related peptide in mesenteric resistance arteries of early pregnant rats.

van Eijndhoven HW, Janssen GM, Aardenburg R, Spaanderman ME, Peeters LL, De Mey JG.

J Vasc Res. 2008;45(4):350-6. doi: 10.1159/000119754. Epub 2008 Mar 10.

PMID:
18332633
33.

Single-cell A3243G mitochondrial DNA mutation load assays for segregation analysis.

Jahangir Tafrechi RS, van de Rijke FM, Allallou A, Larsson C, Sloos WC, van de Sande M, Wählby C, Janssen GM, Raap AK.

J Histochem Cytochem. 2007 Nov;55(11):1159-66. Epub 2007 Aug 6.

34.

The A3243G tRNALeu(UUR) mutation induces mitochondrial dysfunction and variable disease expression without dominant negative acting translational defects in complex IV subunits at UUR codons.

Janssen GM, Hensbergen PJ, van Bussel FJ, Balog CI, Maassen JA, Deelder AM, Raap AK.

Hum Mol Genet. 2007 Oct 15;16(20):2472-81. Epub 2007 Jul 25.

PMID:
17656376
35.

Mitochondrial diabetes and its lessons for common Type 2 diabetes.

Maassen JA, 't Hart LM, Janssen GM, Reiling E, Romijn JA, Lemkes HH.

Biochem Soc Trans. 2006 Nov;34(Pt 5):819-23.

PMID:
17052206
36.

Sustained activation of the mammalian target of rapamycin nutrient sensing pathway is associated with hepatic insulin resistance, but not with steatosis, in mice.

Korsheninnikova E, van der Zon GC, Voshol PJ, Janssen GM, Havekes LM, Grefhorst A, Kuipers F, Reijngoud DJ, Romijn JA, Ouwens DM, Maassen JA.

Diabetologia. 2006 Dec;49(12):3049-57. Epub 2006 Sep 28.

PMID:
17006666
37.

Novel mitochondrial DNA length variants and genetic instability in a family with diabetes and deafness.

Janssen GM, Neu A, 't Hart LM, van de Sande CM, Antonie Maassen J.

Exp Clin Endocrinol Diabetes. 2006 Apr;114(4):168-74.

PMID:
16705548
38.

New insights in the molecular pathogenesis of the maternally inherited diabetes and deafness syndrome.

Maassen JA, Jahangir Tafrechi RS, Janssen GM, Raap AK, Lemkes HH, 't Hart LM.

Endocrinol Metab Clin North Am. 2006 Jun;35(2):385-96, x-xi. Review.

PMID:
16632100
39.

Distinct nuclear gene expression profiles in cells with mtDNA depletion and homoplasmic A3243G mutation.

Jahangir Tafrechi RS, Svensson PJ, Janssen GM, Szuhai K, Maassen JA, Raap AK.

Mutat Res. 2005 Oct 15;578(1-2):43-52.

PMID:
16202796
40.

Molecular mechanisms of mitochondrial diabetes (MIDD).

Maassen JA, Janssen GM, 't Hart LM.

Ann Med. 2005;37(3):213-21. Review.

PMID:
16019720
41.

High sodium intake increases blood pressure and alters renal function in intrauterine growth-retarded rats.

Sanders MW, Fazzi GE, Janssen GM, Blanco CE, De Mey JG.

Hypertension. 2005 Jul;46(1):71-5. Epub 2005 Jun 13.

PMID:
15956110
42.

Evidence that the mitochondrial leucyl tRNA synthetase (LARS2) gene represents a novel type 2 diabetes susceptibility gene.

't Hart LM, Hansen T, Rietveld I, Dekker JM, Nijpels G, Janssen GM, Arp PA, Uitterlinden AG, Jørgensen T, Borch-Johnsen K, Pols HA, Pedersen O, van Duijn CM, Heine RJ, Maassen JA.

Diabetes. 2005 Jun;54(6):1892-5.

43.

In situ metal precipitation in a zinc-contaminated, aerobic sandy aquifer by means of biological sulfate reduction.

Janssen GM, Temminghoff EJ.

Environ Sci Technol. 2004 Jul 15;38(14):4002-11.

PMID:
15298212
44.

Role of the Rhoa/Rho kinase system in flow-related remodeling of rat mesenteric small arteries in vivo.

Wesselman JP, Kuijs R, Hermans JJ, Janssen GM, Fazzi GE, van Essen H, Evelo CT, Struijker-Boudier HA, De Mey JG.

J Vasc Res. 2004 May-Jun;41(3):277-90. Epub 2004 Jun 7.

PMID:
15192268
45.

Reduced uteroplacental blood flow alters renal arterial reactivity and glomerular properties in the rat offspring.

Sanders MW, Fazzi GE, Janssen GM, de Leeuw PW, Blanco CE, De Mey JG.

Hypertension. 2004 Jun;43(6):1283-9. Epub 2004 Apr 26.

PMID:
15117909
46.

Mitochondrial diabetes: molecular mechanisms and clinical presentation.

Maassen JA, 'T Hart LM, Van Essen E, Heine RJ, Nijpels G, Jahangir Tafrechi RS, Raap AK, Janssen GM, Lemkes HH.

Diabetes. 2004 Feb;53 Suppl 1:S103-9. Review.

47.

Chronic moderate hypoxia during in ovo development alters arterial reactivity in chickens.

Ruijtenbeek K, Kessels CG, Janssen BJ, Bitsch NJ, Fazzi GE, Janssen GM, De Mey J, Blanco CE.

Pflugers Arch. 2003 Nov;447(2):158-67. Epub 2003 Oct 1.

PMID:
14520577
48.

Direct and biochemical interaction between dopamine D3 receptor and elongation factor-1Bbetagamma.

Cho DI, Oak MH, Yang HJ, Choi HK, Janssen GM, Kim KM.

Life Sci. 2003 Oct 24;73(23):2991-3004.

PMID:
14519448
49.
50.

Molecular characterization of WFS1 in patients with Wolfram syndrome.

van ven Ouweland JM, Cryns K, Pennings RJ, Walraven I, Janssen GM, Maassen JA, Veldhuijzen BF, Arntzenius AB, Lindhout D, Cremers CW, Van Camp G, Dikkeschei LD.

J Mol Diagn. 2003 May;5(2):88-95.

Supplemental Content

Loading ...
Support Center