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Synthesis and characterization of high affinity fluorogenic α-synuclein probes.

Lengyel-Zhand Z, Ferrie JJ, Janssen B, Hsieh CJ, Graham T, Xu KY, Haney CM, Lee VM, Trojanowski JQ, Petersson EJ, Mach RH.

Chem Commun (Camb). 2020 Feb 27. doi: 10.1039/c9cc09849f. [Epub ahead of print]


Cranial and large vessel activity on positron emission tomography scan at diagnosis and 6 months in giant cell arteritis.

Sammel AM, Hsiao E, Schembri G, Bailey E, Nguyen K, Brewer J, Schrieber L, Janssen B, Youssef P, Fraser CL, Laurent R.

Int J Rheum Dis. 2020 Feb 26. doi: 10.1111/1756-185X.13805. [Epub ahead of print]


Flexibility of the petunia strigolactone receptor DAD2 promotes its interaction with signaling partners.

Lee HW, Sharma P, Janssen BJ, Drummond RSM, Luo Z, Hamiaux C, Collier T, Allison JR, Newcomb RD, Snowden KC.

J Biol Chem. 2020 Feb 17. pii: jbc.RA119.011509. doi: 10.1074/jbc.RA119.011509. [Epub ahead of print]


Genome-wide characterization of 5-hydoxymethylcytosine in melanoma reveals major differences with nevus.

Salgado C, Oosting J, Janssen B, Kumar R, Gruis N, van Doorn R.

Genes Chromosomes Cancer. 2020 Feb 3. doi: 10.1002/gcc.22837. [Epub ahead of print]


Breastfeeding predicts blood mitochondrial DNA content in adolescents.

Cosemans C, Nawrot TS, Janssen BG, Vriens A, Smeets K, Baeyens W, Bruckers L, Den Hond E, Loots I, Nelen V, Van Larebeke N, Schoeters G, Martens D, Plusquin M.

Sci Rep. 2020 Jan 15;10(1):387. doi: 10.1038/s41598-019-57276-z.


Variability of iodine concentrations in the human placenta.

Neven KY, Marien CBD, Janssen BG, Roels HA, Waegeneers N, Nawrot TS, Ruttens A.

Sci Rep. 2020 Jan 13;10(1):161. doi: 10.1038/s41598-019-56775-3.


Haemodynamic effects of the flavonoid quercetin in rats revisited.

Vrolijk MF, van Essen H, Opperhuizen A, Bast A, Janssen BJ.

Br J Pharmacol. 2019 Dec 26. doi: 10.1111/bph.14955. [Epub ahead of print]


Assessing the validity of EQ-5D-5L in people with head & neck cancer: Does a generic quality of life measure perform as well as a disease-specific measure in a patient population?

Davies A, Waylen A, Leary S, Thomas S, Pring M, Janssen B, Beynon R, Lang S, Schimansky S, Hurley K, Ness A.

Oral Oncol. 2020 Feb;101:104504. doi: 10.1016/j.oraloncology.2019.104504. Epub 2019 Dec 10.


Design and structural characterisation of olfactomedin-1 variants as tools for functional studies.

Pronker MF, van den Hoek H, Janssen BJC.

BMC Mol Cell Biol. 2019 Nov 14;20(1):50. doi: 10.1186/s12860-019-0232-1.


The P2X7 receptor tracer [11C]SMW139 as an in vivo marker of neuroinflammation in multiple sclerosis: a first-in man study.

Hagens MHJ, Golla SSV, Janssen B, Vugts DJ, Beaino W, Windhorst AD, O'Brien-Brown J, Kassiou M, Schuit RC, Schwarte LA, de Vries HE, Killestein J, Barkhof F, van Berckel BNM, Lammertsma AA.

Eur J Nucl Med Mol Imaging. 2020 Feb;47(2):379-389. doi: 10.1007/s00259-019-04550-x. Epub 2019 Nov 8.


Placental mitochondrial DNA content is associated with childhood intelligence.

Bijnens EM, Derom C, Weyers S, Janssen BG, Thiery E, Nawrot TS.

J Transl Med. 2019 Nov 8;17(1):361. doi: 10.1186/s12967-019-2105-y.


The Beneficial Effects of UM206 on Wound Healing After Myocardial Infarction in Mice Are Lost in Follow-Up Experiments.

Daskalopoulos EP, Hermans KCM, Debets J, Strzelecka A, Leenders P, Vervoort-Peters L, Janssen BJA, Blankesteijn WM.

Front Cardiovasc Med. 2019 Sep 18;6:118. doi: 10.3389/fcvm.2019.00118. eCollection 2019.


A systematic review of predicted pathogenic PALB2 variants: an analysis of mutational overlap between epithelial cancers.

Janssen B, Bellis S, Koller T, Tischkowitz M, Liau SS.

J Hum Genet. 2020 Jan;65(2):199-205. doi: 10.1038/s10038-019-0680-7. Epub 2019 Oct 16.


[Revised S3 guidelines on schizophrenia : Developmental process and selected recommendations].

Hasan A, Falkai P, Lehmann I, Janssen B, Wobrock T, Zielasek J, Gaebel W.

Nervenarzt. 2020 Jan;91(1):26-33. doi: 10.1007/s00115-019-00813-y. Review. German.


Correction: Verkade, J.M.M.; et al. A Polar Sulfamide Spacer Significantly Enhances the Manufacturability, Stability, and Therapeutic Index of Antibody-Drug Conjugates. Antibodies 2018, 7, 12.

Verkade JMM, Wijdeven MA, Van Geel R, Janssen BMG, Van Berkel SS, Van Delft FL; Antibodies Editorial Office.

Antibodies (Basel). 2018 Aug 30;7(3). pii: E34. doi: 10.3390/antib7030034.


Air pollution-induced placental alterations: an interplay of oxidative stress, epigenetics, and the aging phenotype?

Saenen ND, Martens DS, Neven KY, Alfano R, Bové H, Janssen BG, Roels HA, Plusquin M, Vrijens K, Nawrot TS.

Clin Epigenetics. 2019 Sep 17;11(1):124. doi: 10.1186/s13148-019-0688-z. Review.


Combined transversus abdominis plane and rectus sheath catheters for postoperative analgesia following major hepatopancreatobiliary surgery.

van Laarhoven S, Janssen B, Liau SS.

Ann R Coll Surg Engl. 2020 Jan;102(1):71-72. doi: 10.1308/rcsann.2019.0094. Epub 2019 Sep 18. No abstract available.


Development of brain PET imaging agents: Strategies for imaging neuroinflammation in Alzheimer's disease.

Janssen B, Mach RH.

Prog Mol Biol Transl Sci. 2019;165:371-399. doi: 10.1016/bs.pmbts.2019.04.005. Epub 2019 May 2.


More than time and money: A mixed-methods study of the barriers to safer cattle handling practices.

Scott-Harp D, Peek-Asa C, Rohlman DS, Janssen B.

Am J Ind Med. 2019 Nov;62(11):978-985. doi: 10.1002/ajim.23043. Epub 2019 Aug 26.


Neonatal blood pressure in association with prenatal air pollution exposure, traffic, and land use indicators: An ENVIRONAGE birth cohort study.

Madhloum N, Nawrot TS, Gyselaers W, Roels HA, Bijnens E, Vanpoucke C, Lefebvre W, Janssen BG, Cox B.

Environ Int. 2019 Sep;130:104853. doi: 10.1016/j.envint.2019.05.047. Epub 2019 Jun 18.


Exposure to Environmental Pollutants and Their Association with Biomarkers of Aging: A Multipollutant Approach.

Vriens A, Nawrot TS, Janssen BG, Baeyens W, Bruckers L, Covaci A, De Craemer S, De Henauw S, Den Hond E, Loots I, Nelen V, Schettgen T, Schoeters G, Martens DS, Plusquin M.

Environ Sci Technol. 2019 May 21;53(10):5966-5976. doi: 10.1021/acs.est.8b07141. Epub 2019 May 1.


The Cord Blood Insulin and Mitochondrial DNA Content Related Methylome.

Reimann B, Janssen BG, Alfano R, Ghantous A, Espín-Pérez A, de Kok TM, Saenen ND, Cox B, Robinson O, Chadeau-Hyam M, Penders J, Herceg Z, Vineis P, Nawrot TS, Plusquin M.

Front Genet. 2019 Apr 12;10:325. doi: 10.3389/fgene.2019.00325. eCollection 2019.


Teneurin Structures Are Composed of Ancient Bacterial Protein Domains.

Jackson VA, Busby JN, Janssen BJC, Lott JS, Seiradake E.

Front Neurosci. 2019 Mar 13;13:183. doi: 10.3389/fnins.2019.00183. eCollection 2019. Review.


Diagnostic Accuracy of Positron Emission Tomography/Computed Tomography of the Head, Neck, and Chest for Giant Cell Arteritis: A Prospective, Double-Blind, Cross-Sectional Study.

Sammel AM, Hsiao E, Schembri G, Nguyen K, Brewer J, Schrieber L, Janssen B, Youssef P, Fraser CL, Bailey E, Bailey DL, Roach P, Laurent R.

Arthritis Rheumatol. 2019 Aug;71(8):1319-1328. doi: 10.1002/art.40864. Epub 2019 Jun 12.


Structure and flexibility of the extracellular region of the PirB receptor.

Vlieg HC, Huizinga EG, Janssen BJC.

J Biol Chem. 2019 Mar 22;294(12):4634-4643. doi: 10.1074/jbc.RA118.004396. Epub 2019 Jan 23.


Depressive symptoms, resilience, and personality traits in dry eye disease.

Kaiser T, Janssen B, Schrader S, Geerling G.

Graefes Arch Clin Exp Ophthalmol. 2019 Mar;257(3):591-599. doi: 10.1007/s00417-019-04241-1. Epub 2019 Jan 15.


Identification of new molecular targets for PET imaging of the microglial anti-inflammatory activation state.

Villa A, Klein B, Janssen B, Pedragosa J, Pepe G, Zinnhardt B, Vugts DJ, Gelosa P, Sironi L, Beaino W, Damont A, Dollé F, Jego B, Winkeler A, Ory D, Solin O, Vercouillie J, Funke U, Laner-Plamberger S, Blomster LV, Christophersen P, Vegeto E, Aigner L, Jacobs A, Planas AM, Maggi A, Windhorst AD.

Theranostics. 2018 Oct 27;8(19):5400-5418. doi: 10.7150/thno.25572. eCollection 2018.


Prenatal particulate air pollution exposure and cord blood homocysteine in newborns: Results from the ENVIRONAGE birth cohort.

Hogervorst JGF, Madhloum N, Saenen ND, Janssen BG, Penders J, Vanpoucke C, De Vivo I, Vrijens K, Nawrot TS.

Environ Res. 2019 Jan;168:507-513. doi: 10.1016/j.envres.2018.08.032. Epub 2018 Aug 31.


Angiotensin II-induced hypertension in rats is only transiently accompanied by lower renal oxygenation.

Emans TW, Patinha D, Joles JA, Koeners MP, Janssen BJ, Krediet CTP.

Sci Rep. 2018 Nov 5;8(1):16342. doi: 10.1038/s41598-018-34211-2.


Nitric Oxide Synthase Inhibition Induces Renal Medullary Hypoxia in Conscious Rats.

Emans TW, Janssen BJ, Joles JA, Krediet CTP.

J Am Heart Assoc. 2018 Aug 7;7(15):e009501. doi: 10.1161/JAHA.118.009501.


Residential landscape as a predictor of psychosocial stress in the life course from childhood to adolescence.

Van Aart CJC, Michels N, Sioen I, De Decker A, Bijnens EM, Janssen BG, De Henauw S, Nawrot TS.

Environ Int. 2018 Nov;120:456-463. doi: 10.1016/j.envint.2018.08.028. Epub 2018 Aug 23.


[Return-to-Work after depression - evaluation of a retrospective case-control study of an operational integrated care model].

Reifferscheid A, Wege N, Riesbeck M, Janssen B.

Fortschr Neurol Psychiatr. 2019 Feb;87(2):121-127. doi: 10.1055/s-0043-124593. Epub 2018 Aug 20. German.


Cord blood leptin and insulin levels in association with mitochondrial DNA content.

Vriens A, Plusquin M, Baeyens W, Bruckers L, Den Hond E, Loots I, Nelen V, Schoeters G, Janssen BG, Nawrot TS.

J Transl Med. 2018 Aug 13;16(1):224. doi: 10.1186/s12967-018-1599-z.


MRI-Guided Biopsy as a Tool for Diagnosis and Research of Muscle Disorders.

Lassche S, Janssen BH, IJzermans T, Fütterer JJ, Voermans NC, Heerschap A, Küsters B, Mann RM, van Engelen BG.

J Neuromuscul Dis. 2018;5(3):315-319. doi: 10.3233/JND-180318.


Structural insights into SorCS2-Nerve Growth Factor complex formation.

Leloup N, Chataigner LMP, Janssen BJC.

Nat Commun. 2018 Jul 30;9(1):2979. doi: 10.1038/s41467-018-05405-z.


Enantioselective total synthesis and biological evaluation of (-)-solanacol.

Bromhead LJ, Norman AR, Snowden KC, Janssen BJ, McErlean CSP.

Org Biomol Chem. 2018 Aug 1;16(30):5500-5507. doi: 10.1039/c8ob01287c.


Mitochondrial DNA content in blood and carbon load in airway macrophages. A panel study in elderly subjects.

Bai Y, Casas L, Scheers H, Janssen BG, Nemery B, Nawrot TS.

Environ Int. 2018 Oct;119:47-53. doi: 10.1016/j.envint.2018.06.003. Epub 2018 Jun 19.


Air pollution and the fetal origin of disease: A systematic review of the molecular signatures of air pollution exposure in human placenta.

Luyten LJ, Saenen ND, Janssen BG, Vrijens K, Plusquin M, Roels HA, Debacq-Chainiaux F, Nawrot TS.

Environ Res. 2018 Oct;166:310-323. doi: 10.1016/j.envres.2018.03.025. Epub 2018 Jun 13.


Deletion of endothelial arginase 1 does not improve vasomotor function in diabetic mice.

Chennupati R, Meens MJ, Janssen BJ, van Dijk P, Hakvoort TBM, Lamers WH, De Mey JGR, Koehler SE.

Physiol Rep. 2018 Jun;6(11):e13717. doi: 10.14814/phy2.13717.


Population Norms for the EQ-5D.

Janssen B, Szende A.

In: Szende A, Janssen B, Cabases J, editors. Self-Reported Population Health: An International Perspective based on EQ-5D [Internet]. Dordrecht (NL): Springer; 2014. Chapter 3.
2013 Sep 26.


Data and Methods.

Janssen B, Szende A, Ramos-Goñi JM.

In: Szende A, Janssen B, Cabases J, editors. Self-Reported Population Health: An International Perspective based on EQ-5D [Internet]. Dordrecht (NL): Springer; 2014. Chapter 2.
2013 Sep 26.


Socio-demographic Indicators Based on EQ-5D.

Szende A, Janssen B.

In: Szende A, Janssen B, Cabases J, editors. Self-Reported Population Health: An International Perspective based on EQ-5D [Internet]. Dordrecht (NL): Springer; 2014. Chapter 5.
2013 Sep 26.


Cross-Country Analysis of EQ-5D Data.

Szende A, Janssen B.

In: Szende A, Janssen B, Cabases J, editors. Self-Reported Population Health: An International Perspective based on EQ-5D [Internet]. Dordrecht (NL): Springer; 2014. Chapter 4.
2013 Sep 19.


Identification of the allosteric P2X7 receptor antagonist [11C]SMW139 as a PET tracer of microglial activation.

Janssen B, Vugts DJ, Wilkinson SM, Ory D, Chalon S, Hoozemans JJM, Schuit RC, Beaino W, Kooijman EJM, van den Hoek J, Chishty M, Doméné A, Van der Perren A, Villa A, Maggi A, Molenaar GT, Funke U, Shevchenko RV, Baekelandt V, Bormans G, Lammertsma AA, Kassiou M, Windhorst AD.

Sci Rep. 2018 Apr 26;8(1):6580. doi: 10.1038/s41598-018-24814-0.


A manually annotated Actinidia chinensis var. chinensis (kiwifruit) genome highlights the challenges associated with draft genomes and gene prediction in plants.

Pilkington SM, Crowhurst R, Hilario E, Nardozza S, Fraser L, Peng Y, Gunaseelan K, Simpson R, Tahir J, Deroles SC, Templeton K, Luo Z, Davy M, Cheng C, McNeilage M, Scaglione D, Liu Y, Zhang Q, Datson P, De Silva N, Gardiner SE, Bassett H, Chagné D, McCallum J, Dzierzon H, Deng C, Wang YY, Barron L, Manako K, Bowen J, Foster TM, Erridge ZA, Tiffin H, Waite CN, Davies KM, Grierson EP, Laing WA, Kirk R, Chen X, Wood M, Montefiori M, Brummell DA, Schwinn KE, Catanach A, Fullerton C, Li D, Meiyalaghan S, Nieuwenhuizen N, Read N, Prakash R, Hunter D, Zhang H, McKenzie M, Knäbel M, Harris A, Allan AC, Gleave A, Chen A, Janssen BJ, Plunkett B, Ampomah-Dwamena C, Voogd C, Leif D, Lafferty D, Souleyre EJF, Varkonyi-Gasic E, Gambi F, Hanley J, Yao JL, Cheung J, David KM, Warren B, Marsh K, Snowden KC, Lin-Wang K, Brian L, Martinez-Sanchez M, Wang M, Ileperuma N, Macnee N, Campin R, McAtee P, Drummond RSM, Espley RV, Ireland HS, Wu R, Atkinson RG, Karunairetnam S, Bulley S, Chunkath S, Hanley Z, Storey R, Thrimawithana AH, Thomson S, David C, Testolin R, Huang H, Hellens RP, Schaffer RJ.

BMC Genomics. 2018 Apr 16;19(1):257. doi: 10.1186/s12864-018-4656-3.


Placental promoter methylation of DNA repair genes and prenatal exposure to particulate air pollution: an ENVIRONAGE cohort study.

Neven KY, Saenen ND, Tarantini L, Janssen BG, Lefebvre W, Vanpoucke C, Bollati V, Nawrot TS.

Lancet Planet Health. 2018 Apr;2(4):e174-e183. doi: 10.1016/S2542-5196(18)30049-4. Epub 2018 Apr 4.


Structures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction.

Jackson VA, Meijer DH, Carrasquero M, van Bezouwen LS, Lowe ED, Kleanthous C, Janssen BJC, Seiradake E.

Nat Commun. 2018 Mar 14;9(1):1079. doi: 10.1038/s41467-018-03460-0.


Placental circadian pathway methylation and in utero exposure to fine particle air pollution.

Nawrot TS, Saenen ND, Schenk J, Janssen BG, Motta V, Tarantini L, Cox B, Lefebvre W, Vanpoucke C, Maggioni C, Bollati V.

Environ Int. 2018 May;114:231-241. doi: 10.1016/j.envint.2018.02.034. Epub 2018 Mar 7.


Inhibition of strigolactone receptors by N-phenylanthranilic acid derivatives: Structural and functional insights.

Hamiaux C, Drummond RSM, Luo Z, Lee HW, Sharma P, Janssen BJ, Perry NB, Denny WA, Snowden KC.

J Biol Chem. 2018 Apr 27;293(17):6530-6543. doi: 10.1074/jbc.RA117.001154. Epub 2018 Mar 9.

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