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To STOPP or to START? Potentially inappropriate prescribing in older patients with falls and syncope.

de Ruiter SC, Biesheuvel SS, van Haelst IMM, van Marum RJ, Jansen RWMM.

Maturitas. 2020 Jan;131:65-71. doi: 10.1016/j.maturitas.2019.10.013. Epub 2019 Nov 7.


Epigenomics of Pancreatic Cancer: A Critical Role for Epigenome-Wide Studies.

Singh RR, Reindl KM, Jansen RJ.

Epigenomes. 2019 Mar;3(1). pii: 5. doi: 10.3390/epigenomes3010005. Epub 2019 Jan 19.


Detection of Bacterial DNA in Septic Arthritis Samples Using the MYcrobiota Platform.

Boers SA, Reijnen L, Herpers BL, Hays JP, Jansen R.

J Clin Rheumatol. 2019 Dec;25(8):351-353. doi: 10.1097/RHU.0000000000000901. No abstract available.


The genetic association study of TP53 polymorphisms in Saudi obese patients.

Sabir JSM, El Omri A, Shaik NA, Banaganapalli B, Hajrah NH, Zrelli H, Arfaoui L, Awan ZA, Shaikh Omar AM, Mohammed A, Alharbi MG, Alhebshi AM, Jansen RK, Khan M.

Saudi J Biol Sci. 2019 Nov;26(7):1338-1343. doi: 10.1016/j.sjbs.2019.04.006. Epub 2019 Apr 11.


Population genetic structure of the thick-tailed bushbaby (Otolemur crassicaudatus) from the Soutpansberg Mountain range, Northern South Africa, based on four mitochondrial DNA regions.

Phukuntsi MA, Du Plessis M, Dalton DL, Jansen R, Cuozzo FP, Sauther ML, Kotze A.

Mitochondrial DNA A DNA Mapp Seq Anal. 2019 Nov 25:1-10. doi: 10.1080/24701394.2019.1694015. [Epub ahead of print]


Evaluation of commonly used analysis strategies for epigenome- and transcriptome-wide association studies through replication of large-scale population studies.

van Rooij J, Mandaviya PR, Claringbould A, Felix JF, van Dongen J, Jansen R, Franke L; BIOS consortium, 't Hoen PAC, Heijmans B, van Meurs JBJ.

Genome Biol. 2019 Nov 14;20(1):235. doi: 10.1186/s13059-019-1878-x.


Parallelized microscale fed-batch cultivation in online-monitored microtiter plates: implications of media composition and feed strategies for process design and performance.

Morschett H, Jansen R, Neuendorf C, Moch M, Wiechert W, Oldiges M.

J Ind Microbiol Biotechnol. 2019 Oct 31. doi: 10.1007/s10295-019-02243-w. [Epub ahead of print]


Resurgence of Syphilis in the United States: An Assessment of Contributing Factors.

Schmidt R, Carson PJ, Jansen RJ.

Infect Dis (Auckl). 2019 Oct 16;12:1178633719883282. doi: 10.1177/1178633719883282. eCollection 2019. Review.


Disparities in Secondary Prevention of Atherosclerotic Heart Disease After Coronary Artery Bypass Grafting in Northern Plains American Indians.

Kruger H, Zumwalt C, Guenther R, Jansen R, Warne D, Dyke C.

Health Equity. 2019 Oct 24;3(1):520-526. doi: 10.1089/heq.2019.0030. eCollection 2019.


Fluctuations in Fabaceae mitochondrial genome size and content are both ancient and recent.

Choi IS, Schwarz EN, Ruhlman TA, Khiyami MA, Sabir JSM, Hajarah NH, Sabir MJ, Rabah SO, Jansen RK.

BMC Plant Biol. 2019 Oct 25;19(1):448. doi: 10.1186/s12870-019-2064-8.


Healing of Diabetic Foot Ulcers in Patients Treated at the Copenhagen Wound Healing Center in 1999/2000 and in 2011/2012.

Sørensen MLB, Jansen RB, Wilbek Fabricius T, Jørgensen B, Svendsen OL.

J Diabetes Res. 2019 Sep 8;2019:6429575. doi: 10.1155/2019/6429575. eCollection 2019.


A characterization of cis- and trans-heritability of RNA-Seq-based gene expression.

Ouwens KG, Jansen R, Nivard MG, van Dongen J, Frieser MJ, Hottenga JJ, Arindrarto W, Claringbould A, van Iterson M, Mei H, Franke L, Heijmans BT, A C 't Hoen P, van Meurs J, Brooks AI; BIOS Consortium, Penninx BWJH, Boomsma DI.

Eur J Hum Genet. 2019 Sep 26. doi: 10.1038/s41431-019-0511-5. [Epub ahead of print]


The effect of age on DNA methylation in whole blood among Bangladeshi men and women.

Jansen RJ, Tong L, Argos M, Jasmine F, Rakibuz-Zaman M, Sarwar G, Islam MT, Shahriar H, Islam T, Rahman M, Yunus M, Kibriya MG, Baron JA, Ahsan H, Pierce BL.

BMC Genomics. 2019 Sep 10;20(1):704. doi: 10.1186/s12864-019-6039-9.


A methylation study of long-term depression risk.

Clark SL, Hattab MW, Chan RF, Shabalin AA, Han LKM, Zhao M, Smit JH, Jansen R, Milaneschi Y, Xie LY, van Grootheest G, Penninx BWJH, Aberg KA, van den Oord EJCG.

Mol Psychiatry. 2019 Sep 9. doi: 10.1038/s41380-019-0516-z. [Epub ahead of print]


Lesion Detection and Interobserver Agreement with Advanced Image-Reconstructions for 18F-DCFPyL PET/CT in Patients with Biochemically Recurrent Prostate Cancer.

Jansen BHE, Jansen RW, Wondergem M, Srbljin S, de Klerk JMH, Lissenberg-Witte BI, Vis AN, van Moorselaar RJA, Boellaard R, Hoekstra OS, Oprea-Lager DE.

J Nucl Med. 2019 Sep 3. pii: jnumed.118.222513. doi: 10.2967/jnumed.118.222513. [Epub ahead of print]


Local translation of yeast ERG4 mRNA at the endoplasmic reticulum requires the brefeldin A resistance protein Bfr1.

Manchalu S, Mittal N, Spang A, Jansen RP.

RNA. 2019 Dec;25(12):1661-1672. doi: 10.1261/rna.072017.119. Epub 2019 Aug 27.


Genome assembly and phylogenomic data analyses using plastid data: Contrasting species tree estimation methods.

Gonçalves DJP, Simpson BB, Shimizu GH, Jansen RK, Ortiz EM.

Data Brief. 2019 Jul 27;25:104271. doi: 10.1016/j.dib.2019.104271. eCollection 2019 Aug.


A FRET-based biosensor for the quantification of glucose in culture supernatants of mL scale microbial cultivations.

Otten J, Tenhaef N, Jansen RP, Döbber J, Jungbluth L, Noack S, Oldiges M, Wiechert W, Pohl M.

Microb Cell Fact. 2019 Aug 21;18(1):143. doi: 10.1186/s12934-019-1193-y.


Involvement of inflammatory gene expression pathways in depressed patients with hyperphagia.

de Kluiver H, Jansen R, Milaneschi Y, Penninx BWJH.

Transl Psychiatry. 2019 Aug 20;9(1):193. doi: 10.1038/s41398-019-0528-0.


Global longitudinal strain to predict left ventricular dysfunction in asymptomatic patients with severe mitral valve regurgitation: literature review.

Bijvoet GP, Teske AJ, Chamuleau SAJ, Hart EA, Jansen R, Schaap J.

Neth Heart J. 2019 Aug 13. doi: 10.1007/s12471-019-01318-8. [Epub ahead of print] Review.


FeedER: a feedback-regulated enzyme-based slow-release system for fed-batch cultivation in microtiter plates.

Jansen R, Tenhaef N, Moch M, Wiechert W, Noack S, Oldiges M.

Bioprocess Biosyst Eng. 2019 Nov;42(11):1843-1852. doi: 10.1007/s00449-019-02180-z. Epub 2019 Aug 9.


A closer look at Aspergillus: online monitoring via scattered light enables reproducible phenotyping.

Jansen RP, Beuck C, Moch M, Klein B, Küsters K, Morschett H, Wiechert W, Oldiges M.

Fungal Biol Biotechnol. 2019 Aug 5;6:11. doi: 10.1186/s40694-019-0073-x. eCollection 2019.


Commutability of proficiency testing material containing amitriptyline and nortriptyline: A study within the framework of the Dutch Calibration 2.000 project.

Robijns K, Boone NW, Jansen RTP, Kuypers AWHM, Neef C, Touw DJ.

Clin Chim Acta. 2019 Nov;498:6-10. doi: 10.1016/j.cca.2019.07.036. Epub 2019 Jul 30.


[Care for adolescents and young adults with cancer; the role of a national platform].

van der Graaf WTA, Jansen R, Manten-Horst E.

Ned Tijdschr Geneeskd. 2019 Jul 23;163. pii: D3767. Dutch.


Production optimization and biosynthesis revision of corallopyronin A, a potent anti-filarial antibiotic.

Pogorevc D, Panter F, Schillinger C, Jansen R, Wenzel SC, Müller R.

Metab Eng. 2019 Sep;55:201-211. doi: 10.1016/j.ymben.2019.07.010. Epub 2019 Jul 21.


APEX2-mediated proximity labeling resolves protein networks in Saccharomyces cerevisiae cells.

Singer-Krüger B, Fröhlich T, Franz-Wachtel M, Nalpas N, Macek B, Jansen RP.

FEBS J. 2019 Jul 19. doi: 10.1111/febs.15007. [Epub ahead of print]


Systems Genetics for Evolutionary Studies.

Prins P, Smant G, Arends D, Mulligan MK, Williams RW, Jansen RC.

Methods Mol Biol. 2019;1910:635-652. doi: 10.1007/978-1-4939-9074-0_21.


RNA-Seq in 296 phased trios provides a high-resolution map of genomic imprinting.

Jadhav B, Monajemi R, Gagalova KK, Ho D, Draisma HHM, van de Wiel MA, Franke L, Heijmans BT, van Meurs J, Jansen R; GoNL Consortium; BIOS Consortium, 't Hoen PAC, Sharp AJ, Kiełbasa SM.

BMC Biol. 2019 Jun 24;17(1):50. doi: 10.1186/s12915-019-0674-0.


Design and Development Process of a Youth Depression Screening m-Health Application for Primary Health Care Workers in South Africa and Zambia: An Overview of the MEGA Project.

Lahti M Post Doc, Groen G Prof, Mwape L PhD, Korhonen J MNS, Breet E Post Doc, Chapima F MNS, Coetzee M MNS, Ellilä H PhD, Jansen R MNS, Jonker D MSc, Jörns-Presentati A MA.Soc, Mbanga I RN, Mukwato P PhD, Mundenda J Prof, Mutagubya J Prof, Janse van Rensburg-Bonthuyzen E M.Soc.Sc, Seedat S Prof, Stein DJ Prof, Suliman S PhD, Sukwa T Prof, Turunen TJ BS, Valtins K PhD, van den Heuvel L MMed, Wahila R MS, Grobler G Dr.

Issues Ment Health Nurs. 2019 Jun 21:1-7. doi: 10.1080/01612840.2019.1604919. [Epub ahead of print]


An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis.

Liu J, Carnero-Montoro E, van Dongen J, Lent S, Nedeljkovic I, Ligthart S, Tsai PC, Martin TC, Mandaviya PR, Jansen R, Peters MJ, Duijts L, Jaddoe VWV, Tiemeier H, Felix JF, Willemsen G, de Geus EJC, Chu AY, Levy D, Hwang SJ, Bressler J, Gondalia R, Salfati EL, Herder C, Hidalgo BA, Tanaka T, Moore AZ, Lemaitre RN, Jhun MA, Smith JA, Sotoodehnia N, Bandinelli S, Ferrucci L, Arnett DK, Grallert H, Assimes TL, Hou L, Baccarelli A, Whitsel EA, van Dijk KW, Amin N, Uitterlinden AG, Sijbrands EJG, Franco OH, Dehghan A, Spector TD, Dupuis J, Hivert MF, Rotter JI, Meigs JB, Pankow JS, van Meurs JBJ, Isaacs A, Boomsma DI, Bell JT, Demirkan A, van Duijn CM.

Nat Commun. 2019 Jun 13;10(1):2581. doi: 10.1038/s41467-019-10487-4.


β-Actin mRNA interactome mapping by proximity biotinylation.

Mukherjee J, Hermesh O, Eliscovich C, Nalpas N, Franz-Wachtel M, Maček B, Jansen RP.

Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):12863-12872. doi: 10.1073/pnas.1820737116. Epub 2019 Jun 12.


The ecological effects of selective decontamination of the digestive tract (SDD) on antimicrobial resistance: a 21-year longitudinal single-centre study.

Buitinck S, Jansen R, Rijkenberg S, Wester JPJ, Bosman RJ, van der Meer NJM, van der Voort PHJ.

Crit Care. 2019 Jun 7;23(1):208. doi: 10.1186/s13054-019-2480-z.


Mapping a route to Indigenous engagement in cancer genomic research.

Henare KL, Parker KE, Wihongi H, Blenkiron C, Jansen R, Reid P, Findlay MP, Lawrence B, Hudson M, Print CG.

Lancet Oncol. 2019 Jun;20(6):e327-e335. doi: 10.1016/S1470-2045(19)30307-9. Review.


Incongruence between gene trees and species trees and phylogenetic signal variation in plastid genes.

Gonçalves DJP, Simpson BB, Ortiz EM, Shimizu GH, Jansen RK.

Mol Phylogenet Evol. 2019 Sep;138:219-232. doi: 10.1016/j.ympev.2019.05.022. Epub 2019 May 28.


[Favourable course of cancer of unknown primary].

van de Wouw AJ, van Marion AMW, Jansen RLH.

Ned Tijdschr Geneeskd. 2019 May 22;163. pii: D3829. Dutch.


Highly accelerated rates of genomic rearrangements and nucleotide substitutions in plastid genomes of Passiflora subgenus Decaloba.

Shrestha B, Weng ML, Theriot EC, Gilbert LE, Ruhlman TA, Krosnick SE, Jansen RK.

Mol Phylogenet Evol. 2019 Sep;138:53-64. doi: 10.1016/j.ympev.2019.05.030. Epub 2019 May 23.


The trajectory of C-reactive protein serum levels in older hip fracture patients with postoperative delirium.

Slor CJ, Witlox J, Adamis D, Jansen RWMM, Houdijk APJ, van Gool WA, de Jonghe JFM, Eikelenboom P.

Int J Geriatr Psychiatry. 2019 Oct;34(10):1438-1446. doi: 10.1002/gps.5139. Epub 2019 May 14.


Lost and Found: Return of the Inverted Repeat in the Legume Clade Defined by Its Absence.

Choi IS, Jansen R, Ruhlman T.

Genome Biol Evol. 2019 Apr 1;11(4):1321-1333. doi: 10.1093/gbe/evz076.


Canine parvovirus detected from a serval (Leptailurus serval) in South Africa.

Oosthuizen A, Brettschneider H, Dalton DL, Du Plessis EC, Jansen R, Kotze A, Mitchell EP.

J S Afr Vet Assoc. 2019 Mar 25;90(0):e1-e6. doi: 10.4102/jsava.v90i0.1671.


Kenalactams A-E, Polyene Macrolactams Isolated from Nocardiopsis CG3.

Messaoudi O, Sudarman E, Bendahou M, Jansen R, Stadler M, Wink J.

J Nat Prod. 2019 May 24;82(5):1081-1088. doi: 10.1021/acs.jnatprod.8b00708. Epub 2019 Apr 25.


Biomarker results from a phase II study of MEK1/2 inhibitor binimetinib (MEK162) in patients with advanced NRAS- or BRAF-mutated melanoma.

van Herpen CML, Agarwala SS, Hauschild A, Berking C, Beck JT, Schadendorf D, Jansen R, Queirolo P, Ascierto PA, Blank CU, Heinrich MC, Pal RR, Derti A, Antona V, Nauwelaerts H, Zubel A, Dummer R.

Oncotarget. 2019 Mar 5;10(19):1850-1859. doi: 10.18632/oncotarget.26753. eCollection 2019 Mar 5.


Plastome based phylogenetics and younger crown node age in Pelargonium.

van de Kerke SJ, Shrestha B, Ruhlman TA, Weng ML, Jansen RK, Jones CS, Schlichting CD, Hosseini S, Mohammadin S, Schranz ME, Bakker FT.

Mol Phylogenet Evol. 2019 Aug;137:33-43. doi: 10.1016/j.ympev.2019.03.021. Epub 2019 Mar 26.


FitTetra 2.0 - improved genotype calling for tetraploids with multiple population and parental data support.

Zych K, Gort G, Maliepaard CA, Jansen RC, Voorrips RE.

BMC Bioinformatics. 2019 Mar 20;20(1):148. doi: 10.1186/s12859-019-2703-y.


Understanding and overcoming the pitfalls and biases of next-generation sequencing (NGS) methods for use in the routine clinical microbiological diagnostic laboratory.

Boers SA, Jansen R, Hays JP.

Eur J Clin Microbiol Infect Dis. 2019 Jun;38(6):1059-1070. doi: 10.1007/s10096-019-03520-3. Epub 2019 Mar 5. Review.


Use of enteral amikacin to eliminate carriership with multidrug resistant Enterobacteriaceae.

Nahar J, Buitinck S, Jansen R, Haak EAF, van der Voort PHJ.

J Infect. 2019 May;78(5):409-421. doi: 10.1016/j.jinf.2019.02.007. Epub 2019 Feb 22. No abstract available.


The peroxisome biogenesis factors Pex3 and Pex19: multitasking proteins with disputed functions.

Jansen RLM, van der Klei IJ.

FEBS Lett. 2019 Mar;593(5):457-474. doi: 10.1002/1873-3468.13340. Epub 2019 Mar 5. Review.


Multivariate genome-wide analyses of the well-being spectrum.

Baselmans BML, Jansen R, Ip HF, van Dongen J, Abdellaoui A, van de Weijer MP, Bao Y, Smart M, Kumari M, Willemsen G, Hottenga JJ; BIOS consortium; Social Science Genetic Association Consortium, Boomsma DI, de Geus EJC, Nivard MG, Bartels M.

Nat Genet. 2019 Mar;51(3):445-451. doi: 10.1038/s41588-018-0320-8. Epub 2019 Jan 14.


Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances.

Timmers PR, Mounier N, Lall K, Fischer K, Ning Z, Feng X, Bretherick AD, Clark DW; eQTLGen Consortium, Agbessi M, Ahsan H, Alves I, Andiappan A, Awadalla P, Battle A, Bonder MJ, Boomsma D, Christiansen M, Claringbould A, Deelen P, van Dongen J, Esko T, Favé M, Franke L, Frayling T, Gharib SA, Gibson G, Hemani G, Jansen R, Kalnapenkis A, Kasela S, Kettunen J, Kim Y, Kirsten H, Kovacs P, Krohn K, Kronberg-Guzman J, Kukushkina V, Kutalik Z, Kähönen M, Lee B, Lehtimäki T, Loeffler M, Marigorta U, Metspalu A, van Meurs J, Milani L, Müller-Nurasyid M, Nauck M, Nivard M, Penninx B, Perola M, Pervjakova N, Pierce B, Powell J, Prokisch H, Psaty BM, Raitakari O, Ring S, Ripatti S, Rotzschke O, Ruëger S, Saha A, Scholz M, Schramm K, Seppälä I, Stumvoll M, Sullivan P, Teumer A, Thiery J, Tong L, Tönjes A, Verlouw J, Visscher PM, Võsa U, Völker U, Yaghootkar H, Yang J, Zeng B, Zhang F, Agbessi M, Ahsan H, Alves I, Andiappan A, Awadalla P, Battle A, Bonder MJ, Boomsma D, Christiansen M, Claringbould A, Deelen P, van Dongen J, Esko T, Favé M, Franke L, Frayling T, Gharib SA, Gibson G, Hemani G, Jansen R, Kalnapenkis A, Kasela S, Kettunen J, Kim Y, Kirsten H, Kovacs P, Krohn K, Kronberg-Guzman J, Kukushkina V, Kutalik Z, Kähönen M, Lee B, Lehtimäki T, Loeffler M, Marigorta U, Metspalu A, van Meurs J, Milani L, Müller-Nurasyid M, Nauck M, Nivard M, Penninx B, Perola M, Pervjakova N, Pierce B, Powell J, Prokisch H, Psaty BM, Raitakari O, Ring S, Ripatti S, Rotzschke O, Ruëger S, Saha A, Scholz M, Schramm K, Seppälä I, Stumvoll M, Sullivan P, Teumer A, Thiery J, Tong L, Tönjes A, Verlouw J, Visscher PM, Võsa U, Völker U, Yaghootkar H, Yang J, Zeng B, Zhang F, Shen X, Esko T, Kutalik Z, Wilson JF, Joshi PK.

Elife. 2019 Jan 15;8. pii: e39856. doi: 10.7554/eLife.39856.


What protects against pre-diabetes progressing to diabetes? Observational study of integrated health and social data.

Teng A, Blakely T, Scott N, Jansen R, Masters-Awatere B, Krebs J, Oetzel J.

Diabetes Res Clin Pract. 2019 Feb;148:119-129. doi: 10.1016/j.diabres.2018.12.003. Epub 2019 Jan 8.


Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding.

Boyaci H, Chen J, Jansen R, Darst SA, Campbell EA.

Nature. 2019 Jan;565(7739):382-385. doi: 10.1038/s41586-018-0840-5. Epub 2019 Jan 9.

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