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Items: 28

1.

Determination of an Interaction Network between an Extracellular Bacterial Pathogen and the Human Host.

Griesenauer B, Tran TM, Fortney KR, Janowicz DM, Johnson P, Gao H, Barnes S, Wilson LS, Liu Y, Spinola SM.

MBio. 2019 Jun 18;10(3). pii: e01193-19. doi: 10.1128/mBio.01193-19.

2.

A Class I Haemophilus ducreyi Strain Containing a Class II hgbA Allele Is Partially Attenuated in Humans: Implications for HgbA Vaccine Efficacy Trials.

Leduc I, Fortney KR, Janowicz DM, Zwickl B, Ellinger S, Katz BP, Lin H, Dong Q, Spinola SM.

Infect Immun. 2019 Jun 20;87(7). pii: e00112-19. doi: 10.1128/IAI.00112-19. Print 2019 Jul.

PMID:
31036601
3.

HIV Transmission and Injection Drug Use: Lessons From the Indiana Outbreak.

Janowicz DM.

Top Antivir Med. 2016 Jul/Aug;24(2):90-92. Review.

4.

The Human Skin Microbiome Associates with the Outcome of and Is Influenced by Bacterial Infection.

van Rensburg JJ, Lin H, Gao X, Toh E, Fortney KR, Ellinger S, Zwickl B, Janowicz DM, Katz BP, Nelson DE, Dong Q, Spinola SM.

MBio. 2015 Sep 15;6(5):e01315-15. doi: 10.1128/mBio.01315-15.

5.

DksA and (p)ppGpp have unique and overlapping contributions to Haemophilus ducreyi pathogenesis in humans.

Holley CL, Zhang X, Fortney KR, Ellinger S, Johnson P, Baker B, Liu Y, Janowicz DM, Katz BP, Munson RS Jr, Spinola SM.

Infect Immun. 2015 Aug;83(8):3281-92. doi: 10.1128/IAI.00692-15. Epub 2015 Jun 8.

6.

Phosphoethanolamine Transferase LptA in Haemophilus ducreyi Modifies Lipid A and Contributes to Human Defensin Resistance In Vitro.

Trombley MP, Post DM, Rinker SD, Reinders LM, Fortney KR, Zwickl BW, Janowicz DM, Baye FM, Katz BP, Spinola SM, Bauer ME.

PLoS One. 2015 Apr 22;10(4):e0124373. doi: 10.1371/journal.pone.0124373. eCollection 2015.

7.

Outer membrane protein P4 is not required for virulence in the human challenge model of Haemophilus ducreyi infection.

Janowicz DM, Zwickl BW, Fortney KR, Katz BP, Bauer ME.

BMC Microbiol. 2014 Jun 24;14:166. doi: 10.1186/1471-2180-14-166.

8.

A (p)ppGpp-null mutant of Haemophilus ducreyi is partially attenuated in humans due to multiple conflicting phenotypes.

Holley C, Gangaiah D, Li W, Fortney KR, Janowicz DM, Ellinger S, Zwickl B, Katz BP, Spinola SM.

Infect Immun. 2014 Aug;82(8):3492-502. doi: 10.1128/IAI.01994-14. Epub 2014 Jun 9.

9.

Haemophilus ducreyi Hfq contributes to virulence gene regulation as cells enter stationary phase.

Gangaiah D, Labandeira-Rey M, Zhang X, Fortney KR, Ellinger S, Zwickl B, Baker B, Liu Y, Janowicz DM, Katz BP, Brautigam CA, Munson RS Jr, Hansen EJ, Spinola SM.

MBio. 2014 Feb 11;5(1):e01081-13. doi: 10.1128/mBio.01081-13.

10.

Carbon storage regulator A contributes to the virulence of Haemophilus ducreyi in humans by multiple mechanisms.

Gangaiah D, Li W, Fortney KR, Janowicz DM, Ellinger S, Zwickl B, Katz BP, Spinola SM.

Infect Immun. 2013 Feb;81(2):608-17. doi: 10.1128/IAI.01239-12. Epub 2012 Dec 10.

11.

Permeases of the sap transporter are required for cathelicidin resistance and virulence of Haemophilus ducreyi in humans.

Rinker SD, Gu X, Fortney KR, Zwickl BW, Katz BP, Janowicz DM, Spinola SM, Bauer ME.

J Infect Dis. 2012 Nov;206(9):1407-14. doi: 10.1093/infdis/jis525. Epub 2012 Aug 28.

12.

Sialylation of lipooligosaccharides is dispensable for the virulence of Haemophilus ducreyi in humans.

Spinola SM, Li W, Fortney KR, Janowicz DM, Zwickl B, Katz BP, Munson RS Jr.

Infect Immun. 2012 Feb;80(2):679-87. doi: 10.1128/IAI.05826-11. Epub 2011 Dec 5.

13.

Expression of the Flp proteins by Haemophilus ducreyi is necessary for virulence in human volunteers.

Janowicz DM, Cooney SA, Walsh J, Baker B, Katz BP, Fortney KR, Zwickl BW, Ellinger S, Munson RS Jr.

BMC Microbiol. 2011 Sep 22;11:208. doi: 10.1186/1471-2180-11-208.

14.

A Haemophilus ducreyi CpxR deletion mutant is virulent in human volunteers.

Labandeira-Rey M, Dodd D, Fortney KR, Zwickl B, Katz BP, Janowicz DM, Spinola SM, Hansen EJ.

J Infect Dis. 2011 Jun 15;203(12):1859-65. doi: 10.1093/infdis/jir190.

15.

Activation of the CpxRA system by deletion of cpxA impairs the ability of Haemophilus ducreyi to infect humans.

Spinola SM, Fortney KR, Baker B, Janowicz DM, Zwickl B, Katz BP, Blick RJ, Munson RS Jr.

Infect Immun. 2010 Sep;78(9):3898-904. doi: 10.1128/IAI.00432-10. Epub 2010 Jul 6.

16.

Role played by CD4+FOXP3+ regulatory T Cells in suppression of host responses to Haemophilus ducreyi during experimental infection of human volunteers.

Li W, Tenner-Racz K, Racz P, Janowicz DM, Fortney KR, Katz BP, Spinola SM.

J Infect Dis. 2010 Jun 15;201(12):1839-48. doi: 10.1086/652781.

17.

Haemophilus ducreyi SapA contributes to cathelicidin resistance and virulence in humans.

Mount KL, Townsend CA, Rinker SD, Gu X, Fortney KR, Zwickl BW, Janowicz DM, Spinola SM, Katz BP, Bauer ME.

Infect Immun. 2010 Mar;78(3):1176-84. doi: 10.1128/IAI.01014-09. Epub 2010 Jan 19.

18.

Host-pathogen interplay of Haemophilus ducreyi.

Janowicz DM, Li W, Bauer ME.

Curr Opin Infect Dis. 2010 Feb;23(1):64-9. doi: 10.1097/QCO.0b013e328334c0cb. Review.

19.

Mechanism of human natural killer cell activation by Haemophilus ducreyi.

Li W, Janowicz DM, Fortney KR, Katz BP, Spinola SM.

J Infect Dis. 2009 Aug 15;200(4):590-8. doi: 10.1086/600123.

20.

Inactivation of the Haemophilus ducreyi luxS gene affects the virulence of this pathogen in human subjects.

Labandeira-Rey M, Janowicz DM, Blick RJ, Fortney KR, Zwickl B, Katz BP, Spinola SM, Hansen EJ.

J Infect Dis. 2009 Aug 1;200(3):409-16. doi: 10.1086/600142.

21.

Experimental infection of human volunteers with Haemophilus ducreyi: fifteen years of clinical data and experience.

Janowicz DM, Ofner S, Katz BP, Spinola SM.

J Infect Dis. 2009 Jun 1;199(11):1671-9. doi: 10.1086/598966.

22.

A fibrinogen-binding lipoprotein contributes to the virulence of Haemophilus ducreyi in humans.

Bauer ME, Townsend CA, Doster RS, Fortney KR, Zwickl BW, Katz BP, Spinola SM, Janowicz DM.

J Infect Dis. 2009 Mar 1;199(5):684-92. doi: 10.1086/596656.

23.

Identification of Haemophilus ducreyi genes expressed during human infection.

Bauer ME, Fortney KR, Harrison A, Janowicz DM, Munson RS Jr, Spinola SM.

Microbiology. 2008 Apr;154(Pt 4):1152-60. doi: 10.1099/mic.0.2007/013953-0.

24.

Dysregulated immune profiles for skin and dendritic cells are associated with increased host susceptibility to Haemophilus ducreyi infection in human volunteers.

Humphreys TL, Li L, Li X, Janowicz DM, Fortney KR, Zhao Q, Li W, McClintick J, Katz BP, Wilkes DS, Edenberg HJ, Spinola SM.

Infect Immun. 2007 Dec;75(12):5686-97. Epub 2007 Sep 24.

25.

Experimental infection with Haemophilus ducreyi in persons who are infected with HIV does not cause local or augment systemic viral replication.

Janowicz DM, Tenner-Racz K, Racz P, Humphreys TL, Schnizlein-Bick C, Fortney KR, Zwickl B, Katz BP, Campbell JJ, Ho DD, Spinola SM.

J Infect Dis. 2007 May 15;195(10):1443-51. Epub 2007 Apr 5.

26.

Expression of Haemophilus ducreyi collagen binding outer membrane protein NcaA is required for virulence in swine and human challenge models of chancroid.

Fulcher RA, Cole LE, Janowicz DM, Toffer KL, Fortney KR, Katz BP, Orndorff PE, Spinola SM, Kawula TH.

Infect Immun. 2006 May;74(5):2651-8.

27.

Successful treatment of CMV ventriculitis immune reconstitution syndrome.

Janowicz DM, Johnson RM, Gupta SK.

J Neurol Neurosurg Psychiatry. 2005 Jun;76(6):891-2. No abstract available.

28.

Expression of the LspA1 and LspA2 proteins by Haemophilus ducreyi is required for virulence in human volunteers.

Janowicz DM, Fortney KR, Katz BP, Latimer JL, Deng K, Hansen EJ, Spinola SM.

Infect Immun. 2004 Aug;72(8):4528-33.

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