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Items: 40

1.

Monitoring hippocampal glycine with the computationally designed optical sensor GlyFS.

Zhang WH, Herde MK, Mitchell JA, Whitfield JH, Wulff AB, Vongsouthi V, Sanchez-Romero I, Gulakova PE, Minge D, Breithausen B, Schoch S, Janovjak H, Jackson CJ, Henneberger C.

Nat Chem Biol. 2018 Sep;14(9):861-869. doi: 10.1038/s41589-018-0108-2. Epub 2018 Jul 30.

PMID:
30061718
2.

Optical functionalization of human Class A orphan G-protein-coupled receptors.

Morri M, Sanchez-Romero I, Tichy AM, Kainrath S, Gerrard EJ, Hirschfeld PP, Schwarz J, Janovjak H.

Nat Commun. 2018 May 16;9(1):1950. doi: 10.1038/s41467-018-04342-1.

3.

Green-Light-Induced Inactivation of Receptor Signaling Using Cobalamin-Binding Domains.

Kainrath S, Stadler M, Reichhart E, Distel M, Janovjak H.

Angew Chem Int Ed Engl. 2017 Apr 10;56(16):4608-4611. doi: 10.1002/anie.201611998. Epub 2017 Mar 20.

4.

Method for Developing Optical Sensors Using a Synthetic Dye-Fluorescent Protein FRET Pair and Computational Modeling and Assessment.

Mitchell JA, Zhang WH, Herde MK, Henneberger C, Janovjak H, O'Mara ML, Jackson CJ.

Methods Mol Biol. 2017;1596:89-99. doi: 10.1007/978-1-4939-6940-1_6.

PMID:
28293882
5.

Ancestral Protein Reconstruction and Circular Permutation for Improving the Stability and Dynamic Range of FRET Sensors.

Clifton BE, Whitfield JH, Sanchez-Romero I, Herde MK, Henneberger C, Janovjak H, Jackson CJ.

Methods Mol Biol. 2017;1596:71-87. doi: 10.1007/978-1-4939-6940-1_5.

PMID:
28293881
6.

Optogenetic methods in drug screening: technologies and applications.

Agus V, Janovjak H.

Curr Opin Biotechnol. 2017 Dec;48:8-14. doi: 10.1016/j.copbio.2017.02.006. Epub 2017 Mar 6. Review.

PMID:
28273648
7.

Optogenetic Control of Nodal Signaling Reveals a Temporal Pattern of Nodal Signaling Regulating Cell Fate Specification during Gastrulation.

Sako K, Pradhan SJ, Barone V, Inglés-Prieto Á, Müller P, Ruprecht V, Čapek D, Galande S, Janovjak H, Heisenberg CP.

Cell Rep. 2016 Jul 19;16(3):866-77. doi: 10.1016/j.celrep.2016.06.036. Epub 2016 Jul 7.

8.

A Phytochrome Sensory Domain Permits Receptor Activation by Red Light.

Reichhart E, Ingles-Prieto A, Tichy AM, McKenzie C, Janovjak H.

Angew Chem Int Ed Engl. 2016 May 17;55(21):6339-42. doi: 10.1002/anie.201601736. Epub 2016 Apr 21.

PMID:
27101018
9.

Light at the End of the Protein: Crystal Structure of a C-Terminal Light-Sensing Domain.

Janovjak H.

Structure. 2016 Feb 2;24(2):213-5. doi: 10.1016/j.str.2016.01.002.

10.

Light-assisted small-molecule screening against protein kinases.

Inglés-Prieto Á, Reichhart E, Muellner MK, Nowak M, Nijman SM, Grusch M, Janovjak H.

Nat Chem Biol. 2015 Dec;11(12):952-4. doi: 10.1038/nchembio.1933. Epub 2015 Oct 12.

11.

Flipping the Photoswitch: Ion Channels Under Light Control.

McKenzie CK, Sanchez-Romero I, Janovjak H.

Adv Exp Med Biol. 2015;869:101-17. doi: 10.1007/978-1-4939-2845-3_6. Review.

PMID:
26381942
12.

Construction of a robust and sensitive arginine biosensor through ancestral protein reconstruction.

Whitfield JH, Zhang WH, Herde MK, Clifton BE, Radziejewski J, Janovjak H, Henneberger C, Jackson CJ.

Protein Sci. 2015 Sep;24(9):1412-22. doi: 10.1002/pro.2721. Epub 2015 Aug 18.

13.

Quantification of riboflavin, flavin mononucleotide, and flavin adenine dinucleotide in mammalian model cells by CE with LED-induced fluorescence detection.

Hühner J, Ingles-Prieto Á, Neusüß C, Lämmerhofer M, Janovjak H.

Electrophoresis. 2015 Feb;36(4):518-25. doi: 10.1002/elps.201400451. Epub 2015 Jan 22.

PMID:
25488801
14.

The optogenetic promise for oncology: Episode I.

Ingles-Prieto A, Reichhart E, Schelch K, Janovjak H, Grusch M.

Mol Cell Oncol. 2014 Oct 29;1(4):e964045. doi: 10.4161/23723548.2014.964045. eCollection 2014 Oct-Dec.

15.

Spatio-temporally precise activation of engineered receptor tyrosine kinases by light.

Grusch M, Schelch K, Riedler R, Reichhart E, Differ C, Berger W, Inglés-Prieto Á, Janovjak H.

EMBO J. 2014 Aug 1;33(15):1713-26. doi: 10.15252/embj.201387695. Epub 2014 Jul 1.

16.

Optical control of ligand-gated ion channels.

Szobota S, McKenzie C, Janovjak H.

Methods Mol Biol. 2013;998:417-35. doi: 10.1007/978-1-62703-351-0_32.

PMID:
23529448
17.

Optical control of metabotropic glutamate receptors.

Levitz J, Pantoja C, Gaub B, Janovjak H, Reiner A, Hoagland A, Schoppik D, Kane B, Stawski P, Schier AF, Trauner D, Isacoff EY.

Nat Neurosci. 2013 Apr;16(4):507-16. doi: 10.1038/nn.3346. Epub 2013 Mar 3.

18.

A modern ionotropic glutamate receptor with a K(+) selectivity signature sequence.

Janovjak H, Sandoz G, Isacoff EY.

Nat Commun. 2011;2:232. doi: 10.1038/ncomms1231.

PMID:
21407198
19.

Pharmacology of ionotropic glutamate receptors: A structural perspective.

Stawski P, Janovjak H, Trauner D.

Bioorg Med Chem. 2010 Nov 15;18(22):7759-72. doi: 10.1016/j.bmc.2010.09.012. Epub 2010 Sep 19. Review.

PMID:
20947363
20.

A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing.

Janovjak H, Szobota S, Wyart C, Trauner D, Isacoff EY.

Nat Neurosci. 2010 Aug;13(8):1027-32. doi: 10.1038/nn.2589. Epub 2010 Jun 27.

21.

Periodic forces trigger a complex mechanical response in ubiquitin.

Szymczak P, Janovjak H.

J Mol Biol. 2009 Jul 17;390(3):443-56. doi: 10.1016/j.jmb.2009.04.071. Epub 2009 May 6.

PMID:
19426737
22.

Fully automated single-molecule force spectroscopy for screening applications.

Struckmeier J, Wahl R, Leuschner M, Nunes J, Janovjak H, Geisler U, Hofmann G, Jähnke T, Müller DJ.

Nanotechnology. 2008 Sep 24;19(38):384020. doi: 10.1088/0957-4484/19/38/384020. Epub 2008 Aug 12.

PMID:
21832579
23.

From valleys to ridges: exploring the dynamic energy landscape of single membrane proteins.

Janovjak H, Sapra KT, Kedrov A, Müller DJ.

Chemphyschem. 2008 May 16;9(7):954-66. doi: 10.1002/cphc.200700662. Review.

PMID:
18348129
24.

Free energy of membrane protein unfolding derived from single-molecule force measurements.

Preiner J, Janovjak H, Rankl C, Knaus H, Cisneros DA, Kedrov A, Kienberger F, Muller DJ, Hinterdorfer P.

Biophys J. 2007 Aug 1;93(3):930-7. Epub 2007 May 4.

25.

Deciphering molecular interactions of native membrane proteins by single-molecule force spectroscopy.

Kedrov A, Janovjak H, Sapra KT, Müller DJ.

Annu Rev Biophys Biomol Struct. 2007;36:233-60. Review.

PMID:
17311527
26.

Transmembrane helices have rough energy surfaces.

Janovjak H, Knaus H, Muller DJ.

J Am Chem Soc. 2007 Jan 17;129(2):246-7. No abstract available.

PMID:
17212383
27.

Pulling single bacteriorhodopsin out of a membrane: Comparison of simulation and experiment.

Cieplak M, Filipek S, Janovjak H, Krzyśko KA.

Biochim Biophys Acta. 2006 Apr;1758(4):537-44. Epub 2006 Apr 19.

28.

Bacteriorhodopsin folds into the membrane against an external force.

Kessler M, Gottschalk KE, Janovjak H, Muller DJ, Gaub HE.

J Mol Biol. 2006 Mar 24;357(2):644-54. Epub 2006 Jan 6.

PMID:
16434052
29.

Observing folding pathways and kinetics of a single sodium-proton antiporter from Escherichia coli.

Kedrov A, Janovjak H, Ziegler C, Kuhlbrandt W, Muller DJ.

J Mol Biol. 2006 Jan 6;355(1):2-8. Epub 2005 Nov 8.

PMID:
16298390
30.

Imaging and detecting molecular interactions of single transmembrane proteins.

Janovjak H, Kedrov A, Cisneros DA, Sapra KT, Struckmeier J, Muller DJ.

Neurobiol Aging. 2006 Apr;27(4):546-61. Epub 2005 Oct 25. Review.

PMID:
16253393
31.

Direct measurement of single-molecule visco-elasticity in atomic force microscope force-extension experiments.

Bippes CA, Humphris AD, Stark M, Müller DJ, Janovjak H.

Eur Biophys J. 2006 Feb;35(3):287-92. Epub 2005 Oct 20.

PMID:
16237549
32.

Automated alignment and pattern recognition of single-molecule force spectroscopy data.

Kuhn M, Janovjak H, Hubain M, Müller DJ.

J Microsc. 2005 May;218(Pt 2):125-32.

33.

Complex stability of single proteins explored by forced unfolding experiments.

Janovjak H, Sapra KT, Müller DJ.

Biophys J. 2005 May;88(5):L37-9. Epub 2005 Mar 25.

34.

Molecular force modulation spectroscopy revealing the dynamic response of single bacteriorhodopsins.

Janovjak H, Müller DJ, Humphris AD.

Biophys J. 2005 Feb;88(2):1423-31. Epub 2004 Dec 1.

35.

Hydrodynamic effects in fast AFM single-molecule force measurements.

Janovjak H, Struckmeier J, Müller DJ.

Eur Biophys J. 2005 Feb;34(1):91-6. Epub 2004 Jul 15.

PMID:
15257425
36.

Controlled unfolding and refolding of a single sodium-proton antiporter using atomic force microscopy.

Kedrov A, Ziegler C, Janovjak H, Kühlbrandt W, Müller DJ.

J Mol Biol. 2004 Jul 23;340(5):1143-52.

PMID:
15236973
37.

Probing the energy landscape of the membrane protein bacteriorhodopsin.

Janovjak H, Struckmeier J, Hubain M, Kedrov A, Kessler M, Müller DJ.

Structure. 2004 May;12(5):871-9.

38.

Unfolding pathways of native bacteriorhodopsin depend on temperature.

Janovjak H, Kessler M, Oesterhelt D, Gaub H, Müller DJ.

EMBO J. 2003 Oct 1;22(19):5220-9.

39.

Observing structure, function and assembly of single proteins by AFM.

Müller DJ, Janovjak H, Lehto T, Kuerschner L, Anderson K.

Prog Biophys Mol Biol. 2002 May-Jul;79(1-3):1-43. Review.

PMID:
12225775
40.

Processing of gene expression data generated by quantitative real-time RT-PCR.

Muller PY, Janovjak H, Miserez AR, Dobbie Z.

Biotechniques. 2002 Jun;32(6):1372-4, 1376, 1378-9. Erratum in: Biotechniques. 2002 Sep;33(3):514.

PMID:
12074169

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