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Items: 1 to 50 of 69

1.

Private development companies: transforming academic research into new treatment options for cancer.

Janoff AS.

Mol Interv. 2010 Apr;10(2):65-8. doi: 10.1124/mi.10.2.2. Review. No abstract available.

PMID:
20368364
2.

Safety, pharmacokinetics, and efficacy of CPX-1 liposome injection in patients with advanced solid tumors.

Batist G, Gelmon KA, Chi KN, Miller WH Jr, Chia SK, Mayer LD, Swenson CE, Janoff AS, Louie AC.

Clin Cancer Res. 2009 Jan 15;15(2):692-700. doi: 10.1158/1078-0432.CCR-08-0515.

3.

Optimizing combination chemotherapy by controlling drug ratios.

Mayer LD, Janoff AS.

Mol Interv. 2007 Aug;7(4):216-23. Review.

PMID:
17827442
4.

Ratiometric dosing of anticancer drug combinations: controlling drug ratios after systemic administration regulates therapeutic activity in tumor-bearing mice.

Mayer LD, Harasym TO, Tardi PG, Harasym NL, Shew CR, Johnstone SA, Ramsay EC, Bally MB, Janoff AS.

Mol Cancer Ther. 2006 Jul;5(7):1854-63.

5.

Editorial.

Janoff AS.

J Liposome Res. 2005;15(1-2):1-2. No abstract available.

PMID:
16194923
6.

Controlling the physical behavior and biological performance of liposome formulations through use of surface grafted poly(ethylene glycol).

Allen C, Dos Santos N, Gallagher R, Chiu GN, Shu Y, Li WM, Johnstone SA, Janoff AS, Mayer LD, Webb MS, Bally MB.

Biosci Rep. 2002 Apr;22(2):225-50. Review.

PMID:
12428902
7.

A pharmacokinetic study of amphotericin B lipid complex injection (Abelcet) in patients with definite or probable systemic fungal infections.

Adedoyin A, Swenson CE, Bolcsak LE, Hellmann A, Radowska D, Horwith G, Janoff AS, Branch RA.

Antimicrob Agents Chemother. 2000 Oct;44(10):2900-2.

8.

Phospholipid-bound beta 2-glycoprotein I induces the production of anti-phospholipid antibodies.

Subang R, Levine JS, Janoff AS, Davidson SM, Taraschi TF, Koike T, Minchey SR, Whiteside M, Tannenbaum M, Rauch J.

J Autoimmun. 2000 Aug;15(1):21-32.

PMID:
10936025
9.

Novel inner monolayer fusion assays reveal differential monolayer mixing associated with cation-dependent membrane fusion.

Meers P, Ali S, Erukulla R, Janoff AS.

Biochim Biophys Acta. 2000 Jul 31;1467(1):227-43.

10.

Novel therapeutic nano-particles (lipocores): trapping poorly water soluble compounds.

Perkins WR, Ahmad I, Li X, Hirsh DJ, Masters GR, Fecko CJ, Lee J, Ali S, Nguyen J, Schupsky J, Herbert C, Janoff AS, Mayhew E.

Int J Pharm. 2000 Apr 25;200(1):27-39.

PMID:
10845683
11.

Inhibition of cell division but not nuclear division by 1-O- octadecyl-2-O-methyl-Sn-glycero-3-phosphocholine.

Pushkareva MY, Janoff AS, Mayhew E.

Cell Biol Int. 1999;23(12):817-28.

PMID:
10772756
12.

Growth inhibition of a human ovarian tumor by a novel paclitaxel derivative in SCID mice.

Ahmad I, Masters GR, Schupsky JJ, Nguyen J, Ali S, Janoff AS, Mayhew E.

Oncol Res. 1999;11(6):273-80.

PMID:
10691029
13.

Corrigendum to: 'Elastase-activated liposomal delivery to nucleated cells'.

Pak CC, Erukulla RK, Ahl PL, Janoff AS, Meers P.

Biochim Biophys Acta. 2000 Jan 15;1463(1):195. No abstract available.

PMID:
10631309
14.

Increased cell-surface receptor expression on U-937 cells induced by 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine.

Pushkareva MY, Wannberg SL, Janoff AS, Mayhew E.

Cancer Immunol Immunother. 2000 Jan;48(10):569-78.

PMID:
10630309
15.

Liposomal ET-18-OCH(3) induces cytochrome c-mediated apoptosis independently of CD95 (APO-1/Fas) signaling.

Cuvillier O, Mayhew E, Janoff AS, Spiegel S.

Blood. 1999 Nov 15;94(10):3583-92.

PMID:
10552970
16.

Differential effects of free and liposome-associated 1-O-octadecyl-2-O-methylglycerophosphocholine on protein kinase C.

Spiegel S, Olah Z, Cuvillier O, Edsall LC, Janoff AS.

FEBS Lett. 1999 Jul 2;454(1-2):137-41.

17.

Elastase activated liposomal delivery to nucleated cells.

Pak CC, Erukulla RK, Ahl PL, Janoff AS, Meers P.

Biochim Biophys Acta. 1999 Jul 15;1419(2):111-26. Erratum in: Biochim Biophys Acta 2000 Jan 15;1463(1):following 195.

18.

Doxorubicin physical state in solution and inside liposomes loaded via a pH gradient.

Li X, Hirsh DJ, Cabral-Lilly D, Zirkel A, Gruner SM, Janoff AS, Perkins WR.

Biochim Biophys Acta. 1998 Dec 9;1415(1):23-40.

19.

Triggerable liposomal fusion by enzyme cleavage of a novel peptide-lipid conjugate.

Pak CC, Ali S, Janoff AS, Meers P.

Biochim Biophys Acta. 1998 Jun 24;1372(1):13-27.

20.

In vitro and in vivo antifungal activity of amphotericin B lipid complex: are phospholipases important?

Swenson CE, Perkins WR, Roberts P, Ahmad I, Stevens R, Stevens DA, Janoff AS.

Antimicrob Agents Chemother. 1998 Apr;42(4):767-71.

21.

Cation-dependent fusogenicity of an N-acyl phosphatidylethanolamine.

Shangguan T, Pak CC, Ali S, Janoff AS, Meers P.

Biochim Biophys Acta. 1998 Jan 19;1368(2):171-83.

22.

Enhancement of the in vivo circulation lifetime of L-alpha-distearoylphosphatidylcholine liposomes: importance of liposomal aggregation versus complement opsonization.

Ahl PL, Bhatia SK, Meers P, Roberts P, Stevens R, Dause R, Perkins WR, Janoff AS.

Biochim Biophys Acta. 1997 Oct 23;1329(2):370-82.

23.

Stability of association of 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine with liposomes is composition dependent.

Mayhew E, Ahmad I, Bhatia S, Dause R, Filep J, Janoff AS, Kaisheva E, Perkins WR, Zha Y, Franklin JC.

Biochim Biophys Acta. 1997 Oct 2;1329(1):139-48.

24.

Growth inhibitory effects of liposome-associated 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine.

Peters AC, Ahmad I, Janoff AS, Pushkareva MY, Mayhew E.

Lipids. 1997 Oct;32(10):1045-54.

PMID:
9358430
25.

Association and release of prostaglandin E1 from liposomes.

Davidson SM, Cabral-Lilly D, Maurio FP, Franklin JC, Minchey SR, Ahl PL, Janoff AS.

Biochim Biophys Acta. 1997 Jul 5;1327(1):97-106.

26.

Combination of antitumor ether lipid with lipids of complementary molecular shape reduces its hemolytic activity.

Perkins WR, Dause RB, Li X, Franklin JC, Cabral-Lilly DJ, Zha Y, Dank EH, Mayhew E, Janoff AS.

Biochim Biophys Acta. 1997 Jul 5;1327(1):61-8.

27.

Solute-induced shift of phase transition temperature in Di-saturated PC liposomes: adoption of ripple phase creates osmotic stress.

Perkins WR, Li X, Slater JL, Harmon PA, Ahl PL, Minchey SR, Gruner SM, Janoff AS.

Biochim Biophys Acta. 1997 Jul 5;1327(1):41-51.

28.

Streptokinase entrapment in interdigitation-fusion liposomes improves thrombolysis in an experimental rabbit model.

Perkins WR, Vaughan DE, Plavin SR, Daley WL, Rauch J, Lee L, Janoff AS.

Thromb Haemost. 1997 Jun;77(6):1174-8.

PMID:
9241753
29.

Enhanced therapeutic effects of liposome-associated 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine.

Ahmad I, Filep JJ, Franklin JC, Janoff AS, Masters GR, Pattassery J, Peters A, Schupsky JJ, Zha Y, Mayhew E.

Cancer Res. 1997 May 15;57(10):1915-21.

30.

Behavior of amphotericin B lipid complex in plasma in vitro and in the circulation of rats.

Bhamra R, Sa'ad A, Bolcsak LE, Janoff AS, Swenson CE.

Antimicrob Agents Chemother. 1997 May;41(5):886-92.

31.
32.

Role of lipid polymorphism in pulmonary surfactant.

Perkins WR, Dause RB, Parente RA, Minchey SR, Neuman KC, Gruner SM, Taraschi TF, Janoff AS.

Science. 1996 Jul 19;273(5273):330-2.

PMID:
8662513
33.

Liposomal entrapment of the neutrophil-derived peptide indolicidin endows it with in vivo antifungal activity.

Ahmad I, Perkins WR, Lupan DM, Selsted ME, Janoff AS.

Biochim Biophys Acta. 1995 Jul 26;1237(2):109-14.

34.

Lipid-based formulations of amphotericin B.

Swenson CE, Bolcsak LE, Perkins WR, Janoff AS.

J Antimicrob Chemother. 1995 May;35(5):709-13. No abstract available.

PMID:
7592188
35.

Endogenously opsonized particles divert prostanoid action from lethal to protective in models of experimental endotoxemia.

Eierman DF, Yagami M, Erme SM, Minchey SR, Harmon PA, Pratt KJ, Janoff AS.

Proc Natl Acad Sci U S A. 1995 Mar 28;92(7):2815-9. Erratum in: Proc Natl Acad Sci U S A 1995 Oct 24;92(22):10441.

36.

Contrast material-carrying liposomes: biodistribution, clearance, and imaging characteristics.

Seltzer SE, Blau M, Herman LW, Hooshmand RL, Herman LA, Adams DF, Minchey SR, Janoff AS.

Radiology. 1995 Mar;194(3):775-81.

PMID:
7862978
37.

Synergistic prevention of endotoxin induced mortality in rats by PGE1 and particles.

Eierman DF, Yagami M, Erme SM, Minchey SR, Harmon PA, Janoff AS.

Adv Prostaglandin Thromboxane Leukot Res. 1995;23:341-3. No abstract available.

PMID:
7732866
38.

Interdigitation-fusion: a new method for producing lipid vesicles of high internal volume.

Ahl PL, Chen L, Perkins WR, Minchey SR, Boni LT, Taraschi TF, Janoff AS.

Biochim Biophys Acta. 1994 Nov 2;1195(2):237-44.

PMID:
7947916
39.

The determination of liposome captured volume.

Perkins WR, Minchey SR, Ahl PL, Janoff AS.

Chem Phys Lipids. 1993 Sep;64(1-3):197-217. Review.

PMID:
8242834
40.

Curvature dependent induction of the interdigitated gel phase in DPPC vesicles.

Boni LT, Minchey SR, Perkins WR, Ahl PL, Slater JL, Tate MW, Gruner SM, Janoff AS.

Biochim Biophys Acta. 1993 Mar 14;1146(2):247-57.

PMID:
8452859
41.

The nature of antiphospholipid antibodies.

Rauch J, Janoff AS.

J Rheumatol. 1992 Nov;19(11):1782-5. Review.

PMID:
1491401
42.

Amphotericin B-phospholipid interactions responsible for reduced mammalian cell toxicity.

Perkins WR, Minchey SR, Boni LT, Swenson CE, Popescu MC, Pasternack RF, Janoff AS.

Biochim Biophys Acta. 1992 Jun 30;1107(2):271-82.

PMID:
1504072
43.

Lipids, liposomes, and rational drug design.

Janoff AS.

Lab Invest. 1992 Jun;66(6):655-8. No abstract available.

PMID:
1602736
44.

Biodistribution and imaging characteristics of iotrolan-carrying interdigitation-fusion vesicles.

Seltzer SE, Janoff AS, Blau M, Adams DF, Minchey SR, Boni LT.

Invest Radiol. 1991 Nov;26 Suppl 1:S169-71; discussion S175-6. No abstract available.

PMID:
1808119
45.

Interdigitation-fusion vesicles. A new approach for selective opacification of the RES.

Janoff AS, Minchey SR, Perkins WR, Boni LT, Seltzer SE, Adams DF, Blau M.

Invest Radiol. 1991 Nov;26 Suppl 1:S167-8; discussion S175-6. No abstract available.

PMID:
1808118
46.
47.
48.

Distinguishing plasma lupus anticoagulants from anti-factor antibodies using hexagonal (II) phase phospholipids.

Rauch J, Tannenbaum M, Janoff AS.

Thromb Haemost. 1989 Nov 24;62(3):892-6.

PMID:
2512678
49.

The captured volume of multilamellar vesicles.

Perkins WR, Minchey SR, Ostro MJ, Taraschi TF, Janoff AS.

Biochim Biophys Acta. 1988 Aug 4;943(1):103-7.

PMID:
2840957
50.

Unusual lipid structures selectively reduce the toxicity of amphotericin B.

Janoff AS, Boni LT, Popescu MC, Minchey SR, Cullis PR, Madden TD, Taraschi T, Gruner SM, Shyamsunder E, Tate MW, et al.

Proc Natl Acad Sci U S A. 1988 Aug;85(16):6122-6.

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