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Susceptibility of microbial cells to the modified PIP2-binding sequence of gelsolin anchored on the surface of magnetic nanoparticles.

Bucki R, Niemirowicz-Laskowska K, Deptuła P, Wilczewska AZ, Misiak P, Durnaś B, Fiedoruk K, Piktel E, Mystkowska J, Janmey PA.

J Nanobiotechnology. 2019 Jul 8;17(1):81. doi: 10.1186/s12951-019-0511-1.


Myosin IIA suppresses glioblastoma development in a mechanically sensitive manner.

Picariello HS, Kenchappa RS, Rai V, Crish JF, Dovas A, Pogoda K, McMahon M, Bell ES, Chandrasekharan U, Luu A, West R, Lammerding J, Canoll P, Odde DJ, Janmey PA, Egelhoff T, Rosenfeld SS.

Proc Natl Acad Sci U S A. 2019 Jun 24. pii: 201902847. doi: 10.1073/pnas.1902847116. [Epub ahead of print]


Compression stiffening in biological tissues: On the possibility of classic elasticity origins.

Engstrom TA, Pogoda K, Cruz K, Janmey PA, Schwarz JM.

Phys Rev E. 2019 May;99(5-1):052413. doi: 10.1103/PhysRevE.99.052413.


Sensitivity of multifrequency magnetic resonance elastography and diffusion-weighted imaging to cellular and stromal integrity of liver tissue.

de Schellenberger AA, Tzschätzsch H, Polchlopek B, Bertalan G, Schrank F, Garczynska K, Janmey PA, Braun J, Sack I.

J Biomech. 2019 May 9;88:201-208. doi: 10.1016/j.jbiomech.2019.03.037. Epub 2019 Apr 2.


Compressive tumours cause neuronal damage.

Janmey PA, Pogoda K.

Nat Biomed Eng. 2019 Mar;3(3):171-172. doi: 10.1038/s41551-019-0370-y. No abstract available.


Strong triaxial coupling and anomalous Poisson effect in collagen networks.

Ban E, Wang H, Franklin JM, Liphardt JT, Janmey PA, Shenoy VB.

Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):6790-6799. doi: 10.1073/pnas.1815659116. Epub 2019 Mar 20.


Correction to Soft Hyaluronic Gels Promote Cell Spreading, Stress Fibers, Focal Adhesion, and Membrane Tension by Phosphoinositide Signaling, Not Traction Force.

Mandal K, Aroush DR, Graber ZT, Wu B, Park CY, Fredberg JJ, Guo W, Baumgart T, Janmey PA.

ACS Nano. 2019 Apr 23;13(4):4854. doi: 10.1021/acsnano.9b01435. Epub 2019 Mar 18. No abstract available.


Hyaluronan Disrupts Cardiomyocyte Organization within 3D Fibrin-Based Hydrogels.

Bouhrira N, Galie PA, Janmey PA.

Biophys J. 2019 Apr 2;116(7):1340-1347. doi: 10.1016/j.bpj.2019.02.018. Epub 2019 Feb 26.


Inhibition of inflammatory response in human keratinocytes by magnetic nanoparticles functionalized with PBP10 peptide derived from the PIP2-binding site of human plasma gelsolin.

Piktel E, Wnorowska U, Cieśluk M, Deptula P, Pogoda K, Misztalewska-Turkowicz I, Paprocka P, Niemirowicz-Laskowska K, Wilczewska AZ, Janmey PA, Bucki R.

J Nanobiotechnology. 2019 Feb 2;17(1):22. doi: 10.1186/s12951-019-0455-5.


Lateral distribution of phosphatidylinositol 4,5-bisphosphate in membranes regulates formin- and ARP2/3-mediated actin nucleation.

Bucki R, Wang YH, Yang C, Kandy SK, Fatunmbi O, Bradley R, Pogoda K, Svitkina T, Radhakrishnan R, Janmey PA.

J Biol Chem. 2019 Mar 22;294(12):4704-4722. doi: 10.1074/jbc.RA118.005552. Epub 2019 Jan 28.


Cell-matrix tension contributes to hypoxia in astrocyte-seeded viscoelastic hydrogels composed of collagen and hyaluronan.

Bowers HC, Fiori ML, Khadela JB, Janmey PA, Galie PA.

Exp Cell Res. 2019 Mar 1;376(1):49-57. doi: 10.1016/j.yexcr.2019.01.012. Epub 2019 Jan 15.


Salmon fibrinogen and chitosan scaffold for tissue engineering: in vitro and in vivo evaluation.

Laidmäe I, Ērglis K, Cēbers A, Janmey PA, Uibo R.

J Mater Sci Mater Med. 2018 Nov 30;29(12):182. doi: 10.1007/s10856-018-6192-8.


Soft Hyaluronic Gels Promote Cell Spreading, Stress Fibers, Focal Adhesion, and Membrane Tension by Phosphoinositide Signaling, Not Traction Force.

Mandal K, Raz-Ben Aroush D, Graber ZT, Wu B, Park CY, Fredberg JJ, Guo W, Baumgart T, Janmey PA.

ACS Nano. 2019 Jan 22;13(1):203-214. doi: 10.1021/acsnano.8b05286. Epub 2018 Dec 14. Erratum in: ACS Nano. 2019 Apr 23;13(4):4854.


Mechanosensing at Cellular Interfaces.

Leiphart RJ, Chen D, Peredo AP, Loneker AE, Janmey PA.

Langmuir. 2019 Jun 11;35(23):7509-7519. doi: 10.1021/acs.langmuir.8b02841. Epub 2018 Nov 2.


Plasma Gelsolin: Indicator of Inflammation and Its Potential as a Diagnostic Tool and Therapeutic Target.

Piktel E, Levental I, Durnaś B, Janmey PA, Bucki R.

Int J Mol Sci. 2018 Aug 25;19(9). pii: E2516. doi: 10.3390/ijms19092516. Review.


Regulation of actin assembly by PI(4,5)P2 and other inositol phospholipids: An update on possible mechanisms.

Janmey PA, Bucki R, Radhakrishnan R.

Biochem Biophys Res Commun. 2018 Nov 25;506(2):307-314. doi: 10.1016/j.bbrc.2018.07.155. Epub 2018 Aug 13. Review.


Bactericidal and immunomodulatory properties of magnetic nanoparticles functionalized by 1,4-dihydropyridines.

Niemirowicz-Laskowska K, Głuszek K, Piktel E, Pajuste K, Durnaś B, Król G, Wilczewska AZ, Janmey PA, Plotniece A, Bucki R.

Int J Nanomedicine. 2018 Jun 11;13:3411-3424. doi: 10.2147/IJN.S157564. eCollection 2018.


A comparison of methods to assess cell mechanical properties.

Wu PH, Aroush DR, Asnacios A, Chen WC, Dokukin ME, Doss BL, Durand-Smet P, Ekpenyong A, Guck J, Guz NV, Janmey PA, Lee JSH, Moore NM, Ott A, Poh YC, Ros R, Sander M, Sokolov I, Staunton JR, Wang N, Whyte G, Wirtz D.

Nat Methods. 2018 Jul;15(7):491-498. doi: 10.1038/s41592-018-0015-1. Epub 2018 Jun 18.


Similar Biophysical Abnormalities in Glomeruli and Podocytes from Two Distinct Models.

Embry AE, Liu Z, Henderson JM, Byfield FJ, Liu L, Yoon J, Wu Z, Cruz K, Moradi S, Gillombardo CB, Hussain RZ, Doelger R, Stuve O, Chang AN, Janmey PA, Bruggeman LA, Miller RT.

J Am Soc Nephrol. 2018 May;29(5):1501-1512. doi: 10.1681/ASN.2017050475. Epub 2018 Mar 23.


Glial Tissue Mechanics and Mechanosensing by Glial Cells.

Pogoda K, Janmey PA.

Front Cell Neurosci. 2018 Feb 21;12:25. doi: 10.3389/fncel.2018.00025. eCollection 2018. Review.


Matching material and cellular timescales maximizes cell spreading on viscoelastic substrates.

Gong Z, Szczesny SE, Caliari SR, Charrier EE, Chaudhuri O, Cao X, Lin Y, Mauck RL, Janmey PA, Burdick JA, Shenoy VB.

Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):E2686-E2695. doi: 10.1073/pnas.1716620115. Epub 2018 Mar 5.


Targeting polyelectrolyte networks in purulent body fluids to modulate bactericidal properties of some antibiotics.

Bucki R, Durnaś B, Wątek M, Piktel E, Cruz K, Wolak P, Savage PB, Janmey PA.

Infect Drug Resist. 2018 Jan 11;11:77-86. doi: 10.2147/IDR.S145337. eCollection 2018.


Control of cell morphology and differentiation by substrates with independently tunable elasticity and viscous dissipation.

Charrier EE, Pogoda K, Wells RG, Janmey PA.

Nat Commun. 2018 Jan 31;9(1):449. doi: 10.1038/s41467-018-02906-9.


Soft Substrates Containing Hyaluronan Mimic the Effects of Increased Stiffness on Morphology, Motility, and Proliferation of Glioma Cells.

Pogoda K, Bucki R, Byfield FJ, Cruz K, Lee T, Marcinkiewicz C, Janmey PA.

Biomacromolecules. 2017 Oct 9;18(10):3040-3051. doi: 10.1021/acs.biomac.7b00324. Epub 2017 Sep 14.


Mechanotransduction in cancer.

Chin L, Xia Y, Discher DE, Janmey PA.

Curr Opin Chem Eng. 2016 Feb;11:77-84. doi: 10.1016/j.coche.2016.01.011. Epub 2016 Feb 16.


Biochemical and Cellular Determinants of Renal Glomerular Elasticity.

Embry AE, Mohammadi H, Niu X, Liu L, Moe B, Miller-Little WA, Lu CY, Bruggeman LA, McCulloch CA, Janmey PA, Miller RT.

PLoS One. 2016 Dec 12;11(12):e0167924. doi: 10.1371/journal.pone.0167924. eCollection 2016.


Measuring the Stiffness of Ex Vivo Mouse Aortas Using Atomic Force Microscopy.

Bae YH, Liu SL, Byfield FJ, Janmey PA, Assoian RK.

J Vis Exp. 2016 Oct 19;(116). doi: 10.3791/54630.


Cholesterol-Dependent Phase-Demixing in Lipid Bilayers as a Switch for the Activity of the Phosphoinositide-Binding Cytoskeletal Protein Gelsolin.

Wang YH, Bucki R, Janmey PA.

Biochemistry. 2016 Jun 21;55(24):3361-9. doi: 10.1021/acs.biochem.5b01363. Epub 2016 Jun 9.


Elasticity of fibrous networks under uniaxial prestress.

Vahabi M, Sharma A, Licup AJ, van Oosten AS, Galie PA, Janmey PA, MacKintosh FC.

Soft Matter. 2016 Jun 14;12(22):5050-60. doi: 10.1039/c6sm00606j. Epub 2016 May 13.


Methods for Determining the Cellular Functions of Vimentin Intermediate Filaments.

Ridge KM, Shumaker D, Robert A, Hookway C, Gelfand VI, Janmey PA, Lowery J, Guo M, Weitz DA, Kuczmarski E, Goldman RD.

Methods Enzymol. 2016;568:389-426. doi: 10.1016/bs.mie.2015.09.036. Epub 2015 Dec 19.


Mechanical Properties of Intermediate Filament Proteins.

Charrier EE, Janmey PA.

Methods Enzymol. 2016;568:35-57. doi: 10.1016/bs.mie.2015.09.009. Epub 2015 Nov 3.


Uncoupling shear and uniaxial elastic moduli of semiflexible biopolymer networks: compression-softening and stretch-stiffening.

van Oosten AS, Vahabi M, Licup AJ, Sharma A, Galie PA, MacKintosh FC, Janmey PA.

Sci Rep. 2016 Jan 13;6:19270. doi: 10.1038/srep19270.


Normal and Fibrotic Rat Livers Demonstrate Shear Strain Softening and Compression Stiffening: A Model for Soft Tissue Mechanics.

Perepelyuk M, Chin L, Cao X, van Oosten A, Shenoy VB, Janmey PA, Wells RG.

PLoS One. 2016 Jan 6;11(1):e0146588. doi: 10.1371/journal.pone.0146588. eCollection 2016.


Salmon-derived thrombin inhibits development of chronic pain through an endothelial barrier protective mechanism dependent on APC.

Smith JR, Galie PA, Slochower DR, Weisshaar CL, Janmey PA, Winkelstein BA.

Biomaterials. 2016 Feb;80:96-105. doi: 10.1016/j.biomaterials.2015.11.062. Epub 2015 Dec 2.


A comparison of hyperelastic constitutive models applicable to brain and fat tissues.

Mihai LA, Chin L, Janmey PA, Goriely A.

J R Soc Interface. 2015 Sep 6;12(110):0486. doi: 10.1098/rsif.2015.0486.


Bactericidal Activity of Ceragenin CSA-13 in Cell Culture and in an Animal Model of Peritoneal Infection.

Bucki R, Niemirowicz K, Wnorowska U, Byfield FJ, Piktel E, Wątek M, Janmey PA, Savage PB.

Antimicrob Agents Chemother. 2015 Oct;59(10):6274-82. doi: 10.1128/AAC.00653-15. Epub 2015 Jul 27.


Filamin A Mediates Wound Closure by Promoting Elastic Deformation and Maintenance of Tension in the Collagen Matrix.

Mohammadi H, Pinto VI, Wang Y, Hinz B, Janmey PA, McCulloch CA.

J Invest Dermatol. 2015 Nov;135(11):2852-2861. doi: 10.1038/jid.2015.251. Epub 2015 Jul 2.


Relationship of and cross-talk between physical and biologic properties of the glomerulus.

Miller RT, Janmey PA.

Curr Opin Nephrol Hypertens. 2015 Jul;24(4):393-400. doi: 10.1097/MNH.0000000000000138. Review.


Polyelectrolyte-mediated increase of biofilm mass formation.

Bucki R, Niemirowicz K, Wnorowska U, Wątek M, Byfield FJ, Cruz K, Wróblewska M, Janmey PA.

BMC Microbiol. 2015 Jun 6;15:117. doi: 10.1186/s12866-015-0457-x.


Synthesis and structure-activity relationships of novel cationic lipids with anti-inflammatory and antimicrobial activities.

Myint M, Bucki R, Janmey PA, Diamond SL.

Bioorg Med Chem Lett. 2015 Jul 15;25(14):2837-43. doi: 10.1016/j.bmcl.2015.04.104. Epub 2015 May 11.


The (dys)functional extracellular matrix.

Freedman BR, Bade ND, Riggin CN, Zhang S, Haines PG, Ong KL, Janmey PA.

Biochim Biophys Acta. 2015 Nov;1853(11 Pt B):3153-64. doi: 10.1016/j.bbamcr.2015.04.015. Epub 2015 Apr 27. Review.


Physical chemistry and membrane properties of two phosphatidylinositol bisphosphate isomers.

Slochower DR, Wang YH, Radhakrishnan R, Janmey PA.

Phys Chem Chem Phys. 2015 May 21;17(19):12608-15. doi: 10.1039/c5cp00862j.


Flightless I interacts with NMMIIA to promote cell extension formation, which enables collagen remodeling.

Arora PD, Wang Y, Bresnick A, Janmey PA, McCulloch CA.

Mol Biol Cell. 2015 Jun 15;26(12):2279-97. doi: 10.1091/mbc.E14-11-1536. Epub 2015 Apr 15.


Bactericidal activities of cathelicidin LL-37 and select cationic lipids against the hypervirulent Pseudomonas aeruginosa strain LESB58.

Wnorowska U, Niemirowicz K, Myint M, Diamond SL, Wróblewska M, Savage PB, Janmey PA, Bucki R.

Antimicrob Agents Chemother. 2015 Jul;59(7):3808-15. doi: 10.1128/AAC.00421-15. Epub 2015 Apr 13.


Compression stiffening of brain and its effect on mechanosensing by glioma cells.

Pogoda K, Chin L, Georges PC, Byfield FJ, Bucki R, Kim R, Weaver M, Wells RG, Marcinkiewicz C, Janmey PA.

New J Phys. 2014 Jul;16:075002.


Enhancement of Pulmozyme activity in purulent sputum by combination with poly-aspartic acid or gelsolin.

Bucki R, Cruz K, Pogoda K, Eggert A, Chin L, Ferrin M, Imbesi G, Hadjiliadis D, Janmey PA.

J Cyst Fibros. 2015 Sep;14(5):587-93. doi: 10.1016/j.jcf.2015.02.001. Epub 2015 Feb 13.


Application of multiple levels of fluid shear stress to endothelial cells plated on polyacrylamide gels.

Galie PA, van Oosten A, Chen CS, Janmey PA.

Lab Chip. 2015 Feb 21;15(4):1205-12. doi: 10.1039/c4lc01236d.


Increased levels of sphingosine-1-phosphate in cerebrospinal fluid of patients diagnosed with tick-borne encephalitis.

Kułakowska A, Byfield FJ, Zendzian-Piotrowska M, Zajkowska JM, Drozdowski W, Mroczko B, Janmey PA, Bucki R.

J Neuroinflammation. 2014 Nov 25;11:193. doi: 10.1186/s12974-014-0193-4.


Clamping down on tumor proliferation.

Chalut KJ, Janmey PA.

Biophys J. 2014 Oct 21;107(8):1775-1776. doi: 10.1016/j.bpj.2014.09.004. No abstract available.


Inelastic behaviour of collagen networks in cell-matrix interactions and mechanosensation.

Mohammadi H, Arora PD, Simmons CA, Janmey PA, McCulloch CA.

J R Soc Interface. 2015 Jan 6;12(102):20141074. doi: 10.1098/rsif.2014.1074.

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