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Items: 1 to 50 of 79

1.

Immunophenotyping of Murine Precursor B-Cell Leukemia/Lymphoma: A Comparison of Immunohistochemistry and Flow Cytometry.

Janke LJ, Mullighan CG, Dang J, Rehg JE.

Vet Pathol. 2019 Jun 6:300985819852138. doi: 10.1177/0300985819852138. [Epub ahead of print]

PMID:
31170889
2.

Asparaginase combined with discontinuous dexamethasone improves antileukemic efficacy without increasing osteonecrosis in preclinical models.

Karol SE, Janke LJ, Panetta JC, Ramsey LB, Cai X, Payton MA, Jenkins DA, Evans WE, Relling MV.

PLoS One. 2019 May 6;14(5):e0216328. doi: 10.1371/journal.pone.0216328. eCollection 2019.

3.

Genomic subtyping and therapeutic targeting of acute erythroleukemia.

Iacobucci I, Wen J, Meggendorfer M, Choi JK, Shi L, Pounds SB, Carmichael CL, Masih KE, Morris SM, Lindsley RC, Janke LJ, Alexander TB, Song G, Qu C, Li Y, Payne-Turner D, Tomizawa D, Kiyokawa N, Valentine M, Valentine V, Basso G, Locatelli F, Enemark EJ, Kham SKY, Yeoh AEJ, Ma X, Zhou X, Sioson E, Rusch M, Ries RE, Stieglitz E, Hunger SP, Wei AH, To LB, Lewis ID, D'Andrea RJ, Kile BT, Brown AL, Scott HS, Hahn CN, Marlton P, Pei D, Cheng C, Loh ML, Ebert BL, Meshinchi S, Haferlach T, Mullighan CG.

Nat Genet. 2019 Apr;51(4):694-704. doi: 10.1038/s41588-019-0375-1. Epub 2019 Mar 29.

PMID:
30926971
4.

Bloodstream infections exacerbate incidence and severity of symptomatic glucocorticoid-induced osteonecrosis.

Finch ER, Janke LJ, Smith CA, Karol SE, Pei D, Cheng C, Kaste SC, Inaba H, Pui CH, Wolf J, Relling MV.

Pediatr Blood Cancer. 2019 Jun;66(6):e27669. doi: 10.1002/pbc.27669. Epub 2019 Feb 13.

PMID:
30758124
5.

Ensiling fermentation reveals pre-treatment effects for anaerobic digestion of sugarcane biomass: An assessment of ensiling additives on methane potential.

Janke L, McCabe BK, Harris P, Hill A, Lee S, Weinrich S, Marchuk S, Baillie C.

Bioresour Technol. 2019 May;279:398-403. doi: 10.1016/j.biortech.2019.01.143. Epub 2019 Jan 31.

PMID:
30744925
6.

L-carnitine does not ameliorate asparaginase-associated hepatotoxicity in a C57BL6 mouse model.

Liu Y, Janke LJ, Li L, Relling MV.

Leuk Lymphoma. 2019 Feb 4:1-3. doi: 10.1080/10428194.2019.1571198. [Epub ahead of print] No abstract available.

PMID:
30714450
7.

Classification, Scoring, and Quantification of Cell Death in Tissue Sections.

Janke LJ, Ward JM, Vogel P.

Vet Pathol. 2019 Jan;56(1):33-38. doi: 10.1177/0300985818800026. Epub 2018 Oct 3.

PMID:
30278838
8.

ETV7 is an essential component of a rapamycin-insensitive mTOR complex in cancer.

Harwood FC, Klein Geltink RI, O'Hara BP, Cardone M, Janke L, Finkelstein D, Entin I, Paul L, Houghton PJ, Grosveld GC.

Sci Adv. 2018 Sep 12;4(9):eaar3938. doi: 10.1126/sciadv.aar3938. eCollection 2018 Sep.

9.

The genetic basis and cell of origin of mixed phenotype acute leukaemia.

Alexander TB, Gu Z, Iacobucci I, Dickerson K, Choi JK, Xu B, Payne-Turner D, Yoshihara H, Loh ML, Horan J, Buldini B, Basso G, Elitzur S, de Haas V, Zwaan CM, Yeoh A, Reinhardt D, Tomizawa D, Kiyokawa N, Lammens T, De Moerloose B, Catchpoole D, Hori H, Moorman A, Moore AS, Hrusak O, Meshinchi S, Orgel E, Devidas M, Borowitz M, Wood B, Heerema NA, Carrol A, Yang YL, Smith MA, Davidsen TM, Hermida LC, Gesuwan P, Marra MA, Ma Y, Mungall AJ, Moore RA, Jones SJM, Valentine M, Janke LJ, Rubnitz JE, Pui CH, Ding L, Liu Y, Zhang J, Nichols KE, Downing JR, Cao X, Shi L, Pounds S, Newman S, Pei D, Guidry Auvil JM, Gerhard DS, Hunger SP, Inaba H, Mullighan CG.

Nature. 2018 Oct;562(7727):373-379. doi: 10.1038/s41586-018-0436-0. Epub 2018 Sep 12.

10.

i3 signaling is associated with sexual dimorphic expression of the clock-controlled output gene Dbp in murine liver.

Singh M, Bergmann L, Lang A, Pexa K, Kuck F, Stibane D, Janke L, Ezzahoini H, Lindecke A, Wiek C, Hanenberg H, Köhrer K, von Gall C, Reinke H, Piekorz RP.

Oncotarget. 2018 Jul 13;9(54):30213-30224. doi: 10.18632/oncotarget.25727. eCollection 2018 Jul 13.

11.

ETV6-NTRK3 induces aggressive acute lymphoblastic leukemia highly sensitive to selective TRK inhibition.

Roberts KG, Janke LJ, Zhao Y, Seth A, Ma J, Finkelstein D, Smith S, Ebata K, Tuch BB, Hunger SP, Mullighan CG.

Blood. 2018 Aug 23;132(8):861-865. doi: 10.1182/blood-2018-05-849554. Epub 2018 Jun 7. No abstract available.

PMID:
29880614
12.

Preclinical evaluation of NUDT15-guided thiopurine therapy and its effects on toxicity and antileukemic efficacy.

Nishii R, Moriyama T, Janke LJ, Yang W, Suiter CC, Lin TN, Li L, Kihira K, Toyoda H, Hofmann U, Schwab M, Takagi M, Morio T, Manabe A, Kham S, Jiang N, Rabin KR, Kato M, Koh K, Yeoh AE, Hori H, Yang JJ.

Blood. 2018 May 31;131(22):2466-2474. doi: 10.1182/blood-2017-11-815506. Epub 2018 Mar 23.

13.

Oncogenic role and therapeutic targeting of ABL-class and JAK-STAT activating kinase alterations in Ph-like ALL.

Roberts KG, Yang YL, Payne-Turner D, Lin W, Files JK, Dickerson K, Gu Z, Taunton J, Janke LJ, Chen T, Loh ML, Hunger SP, Mullighan CG.

Blood Adv. 2017 Aug 30;1(20):1657-1671. doi: 10.1182/bloodadvances.2017011296. eCollection 2017 Sep 12.

14.

Functional characterization of the circadian clock in the Antarctic krill, Euphausia superba.

Biscontin A, Wallach T, Sales G, Grudziecki A, Janke L, Sartori E, Bertolucci C, Mazzotta G, De Pittà C, Meyer B, Kramer A, Costa R.

Sci Rep. 2017 Dec 18;7(1):17742. doi: 10.1038/s41598-017-18009-2.

15.

Hypoxia-induced upregulation of BMX kinase mediates therapeutic resistance in acute myeloid leukemia.

van Oosterwijk JG, Buelow DR, Drenberg CD, Vasilyeva A, Li L, Shi L, Wang YD, Finkelstein D, Shurtleff SA, Janke LJ, Pounds S, Rubnitz JE, Inaba H, Pabla N, Baker SD.

J Clin Invest. 2018 Jan 2;128(1):369-380. doi: 10.1172/JCI91893. Epub 2017 Dec 11.

16.

Optimization of semi-continuous anaerobic digestion of sugarcane straw co-digested with filter cake: Effects of macronutrients supplementation on conversion kinetics.

Janke L, Weinrich S, Leite AF, Schüch A, Nikolausz M, Nelles M, Stinner W.

Bioresour Technol. 2017 Dec;245(Pt A):35-43. doi: 10.1016/j.biortech.2017.08.084. Epub 2017 Aug 31.

PMID:
28892704
17.

Upregulated heme biosynthesis, an exploitable vulnerability in MYCN-driven leukemogenesis.

Fukuda Y, Wang Y, Lian S, Lynch J, Nagai S, Fanshawe B, Kandilci A, Janke LJ, Neale G, Fan Y, Sorrentino BP, Roussel MF, Grosveld G, Schuetz JD.

JCI Insight. 2017 Aug 3;2(15). pii: 92409. doi: 10.1172/jci.insight.92409. eCollection 2017 Aug 3.

18.

Identification of OAT1/OAT3 as Contributors to Cisplatin Toxicity.

Hu S, Leblanc AF, Gibson AA, Hong KW, Kim JY, Janke LJ, Li L, Vasilyeva A, Finkelstein DB, Sprowl JA, Sweet DH, Schlatter E, Ciarimboli G, Schellens J, Baker SD, Pabla N, Sparreboom A.

Clin Transl Sci. 2017 Sep;10(5):412-420. doi: 10.1111/cts.12480. Epub 2017 Jul 8.

19.

Differential effects of thiopurine methyltransferase (TPMT) and multidrug resistance-associated protein gene 4 (MRP4) on mercaptopurine toxicity.

Liu C, Janke LJ, Yang JJ, Evans WE, Schuetz JD, Relling MV.

Cancer Chemother Pharmacol. 2017 Aug;80(2):287-293. doi: 10.1007/s00280-017-3361-2. Epub 2017 Jun 16.

20.

Globule Leukocytes and Other Mast Cells in the Mouse Intestine.

Vogel P, Janke L, Gravano DM, Lu M, Sawant DV, Bush D, Shuyu E, Vignali DAA, Pillai A, Rehg JE.

Vet Pathol. 2018 Jan;55(1):76-97. doi: 10.1177/0300985817705174. Epub 2017 May 11.

PMID:
28494703
21.

Genome-Wide Study Links PNPLA3 Variant With Elevated Hepatic Transaminase After Acute Lymphoblastic Leukemia Therapy.

Liu Y, Fernandez CA, Smith C, Yang W, Cheng C, Panetta JC, Kornegay N, Liu C, Ramsey LB, Karol SE, Janke LJ, Larsen EC, Winick N, Carroll WL, Loh ML, Raetz EA, Hunger SP, Devidas M, Yang JJ, Mullighan CG, Zhang J, Evans WE, Jeha S, Pui CH, Relling MV.

Clin Pharmacol Ther. 2017 Jul;102(1):131-140. doi: 10.1002/cpt.629. Epub 2017 Apr 4.

22.

Corrigendum: Noncanonical autophagy inhibits the autoinflammatory, lupus-like response to dying cells.

Martinez J, Cunha LD, Park S, Yang M, Lu Q, Orchard R, Li QZ, Yan M, Janke L, Guy C, Linkermann A, Virgin HW, Green DR.

Nature. 2016 Nov 3;539(7627):124. doi: 10.1038/nature19837. Epub 2016 Sep 28. No abstract available.

PMID:
27680703
23.

Crosstalk of clock gene expression and autophagy in aging.

Kalfalah F, Janke L, Schiavi A, Tigges J, Ix A, Ventura N, Boege F, Reinke H.

Aging (Albany NY). 2016 Aug 28;8(9):1876-1895. doi: 10.18632/aging.101018.

24.

Msh2 deficiency leads to dysmyelination of the corpus callosum, impaired locomotion, and altered sensory function in mice.

Diouf B, Devaraju P, Janke LJ, Fan Y, Frase S, Eddins D, Peters JL, Kim J, Pei D, Cheng C, Zakharenko SS, Evans WE.

Sci Rep. 2016 Aug 1;6:30757. doi: 10.1038/srep30757.

25.

Lessons learned from the microbial ecology resulting from different inoculation strategies for biogas production from waste products of the bioethanol/sugar industry.

Leite AF, Janke L, Harms H, Richnow HH, Nikolausz M.

Biotechnol Biofuels. 2016 Jul 16;9:144. doi: 10.1186/s13068-016-0548-4. eCollection 2016.

26.

Noncanonical autophagy inhibits the autoinflammatory, lupus-like response to dying cells.

Martinez J, Cunha LD, Park S, Yang M, Lu Q, Orchard R, Li QZ, Yan M, Janke L, Guy C, Linkermann A, Virgin HW, Green DR.

Nature. 2016 May 5;533(7601):115-9. doi: 10.1038/nature17950. Epub 2016 Apr 20. Erratum in: Nature. 2016 Nov 3;539(7627):124.

27.

Asparaginase Potentiates Glucocorticoid-Induced Osteonecrosis in a Mouse Model.

Liu C, Janke LJ, Kawedia JD, Ramsey LB, Cai X, Mattano LA Jr, Boyd KL, Funk AJ, Relling MV.

PLoS One. 2016 Mar 11;11(3):e0151433. doi: 10.1371/journal.pone.0151433. eCollection 2016.

28.

Evaluating the Safety of Retroviral Vectors Based on Insertional Oncogene Activation and Blocked Differentiation in Cultured Thymocytes.

Zhou S, Fatima S, Ma Z, Wang YD, Lu T, Janke LJ, Du Y, Sorrentino BP.

Mol Ther. 2016 Jun;24(6):1090-1099. doi: 10.1038/mt.2016.55. Epub 2016 Mar 9.

29.

Enhancing biogas production from vinasse in sugarcane biorefineries: Effects of urea and trace elements supplementation on process performance and stability.

Janke L, Leite AF, Batista K, Silva W, Nikolausz M, Nelles M, Stinner W.

Bioresour Technol. 2016 Oct;217:10-20. doi: 10.1016/j.biortech.2016.01.110. Epub 2016 Feb 4.

PMID:
26873284
30.

Truncating Erythropoietin Receptor Rearrangements in Acute Lymphoblastic Leukemia.

Iacobucci I, Li Y, Roberts KG, Dobson SM, Kim JC, Payne-Turner D, Harvey RC, Valentine M, McCastlain K, Easton J, Yergeau D, Janke LJ, Shao Y, Chen IM, Rusch M, Zandi S, Kornblau SM, Konopleva M, Jabbour E, Paietta EM, Rowe JM, Pui CH, Gastier-Foster J, Gu Z, Reshmi S, Loh ML, Racevskis J, Tallman MS, Wiernik PH, Litzow MR, Willman CL, McPherson JD, Downing JR, Zhang J, Dick JE, Hunger SP, Mullighan CG.

Cancer Cell. 2016 Feb 8;29(2):186-200. doi: 10.1016/j.ccell.2015.12.013.

31.

Regulated lysosomal exocytosis mediates cancer progression.

Machado E, White-Gilbertson S, van de Vlekkert D, Janke L, Moshiach S, Campos Y, Finkelstein D, Gomero E, Mosca R, Qiu X, Morton CL, Annunziata I, d'Azzo A.

Sci Adv. 2015 Dec 18;1(11):e1500603. doi: 10.1126/sciadv.1500603. eCollection 2015 Dec.

32.

Apoptosis-Inducing-Factor-Dependent Mitochondrial Function Is Required for T Cell but Not B Cell Function.

Milasta S, Dillon CP, Sturm OE, Verbist KC, Brewer TL, Quarato G, Brown SA, Frase S, Janke LJ, Perry SS, Thomas PG, Green DR.

Immunity. 2016 Jan 19;44(1):88-102. doi: 10.1016/j.immuni.2015.12.002. Epub 2016 Jan 12.

33.

Comparison of start-up strategies and process performance during semi-continuous anaerobic digestion of sugarcane filter cake co-digested with bagasse.

Janke L, Leite AF, Nikolausz M, Radetski CM, Nelles M, Stinner W.

Waste Manag. 2016 Feb;48:199-208. doi: 10.1016/j.wasman.2015.11.007. Epub 2015 Nov 12.

PMID:
26584558
34.

Apoptosome activation, an important molecular instigator in 6-mercaptopurine induced Leydig cell death.

Morgan JA, Lynch J, Panetta JC, Wang Y, Frase S, Bao J, Zheng J, Opferman JT, Janke L, Green DM, Chemaitilly W, Schuetz JD.

Sci Rep. 2015 Nov 18;5:16488. doi: 10.1038/srep16488.

35.

Biogas Production from Sugarcane Waste: Assessment on Kinetic Challenges for Process Designing.

Janke L, Leite A, Nikolausz M, Schmidt T, Liebetrau J, Nelles M, Stinner W.

Int J Mol Sci. 2015 Aug 31;16(9):20685-703. doi: 10.3390/ijms160920685.

36.

Improved Monitoring of Semi-Continuous Anaerobic Digestion of Sugarcane Waste: Effects of Increasing Organic Loading Rate on Methanogenic Community Dynamics.

Leite AF, Janke L, Lv Z, Harms H, Richnow HH, Nikolausz M.

Int J Mol Sci. 2015 Sep 25;16(10):23210-26. doi: 10.3390/ijms161023210.

37.

Efficacy of Retinoids in IKZF1-Mutated BCR-ABL1 Acute Lymphoblastic Leukemia.

Churchman ML, Low J, Qu C, Paietta EM, Kasper LH, Chang Y, Payne-Turner D, Althoff MJ, Song G, Chen SC, Ma J, Rusch M, McGoldrick D, Edmonson M, Gupta P, Wang YD, Caufield W, Freeman B, Li L, Panetta JC, Baker S, Yang YL, Roberts KG, McCastlain K, Iacobucci I, Peters JL, Centonze VE, Notta F, Dobson SM, Zandi S, Dick JE, Janke L, Peng J, Kodali K, Pagala V, Min J, Mayasundari A, Williams RT, Willman CL, Rowe J, Luger S, Dickins RA, Guy RK, Chen T, Mullighan CG.

Cancer Cell. 2015 Sep 14;28(3):343-56. doi: 10.1016/j.ccell.2015.07.016. Epub 2015 Aug 27.

38.

Optimization of hydrolysis and volatile fatty acids production from sugarcane filter cake: Effects of urea supplementation and sodium hydroxide pretreatment.

Janke L, Leite A, Batista K, Weinrich S, Sträuber H, Nikolausz M, Nelles M, Stinner W.

Bioresour Technol. 2016 Jan;199:235-244. doi: 10.1016/j.biortech.2015.07.117. Epub 2015 Aug 8.

PMID:
26278994
39.

Antileukemic Efficacy of Continuous vs Discontinuous Dexamethasone in Murine Models of Acute Lymphoblastic Leukemia.

Ramsey LB, Janke LJ, Payton MA, Cai X, Paugh SW, Karol SE, Kamdem Kamdem L, Cheng C, Williams RT, Jeha S, Pui CH, Evans WE, Relling MV.

PLoS One. 2015 Aug 7;10(8):e0135134. doi: 10.1371/journal.pone.0135134. eCollection 2015.

40.

Impact of amyloid precursor protein hydrophilic transmembrane residues on amyloid-beta generation.

Oestereich F, Bittner HJ, Weise C, Grohmann L, Janke LK, Hildebrand PW, Multhaup G, Munter LM.

Biochemistry. 2015 May 5;54(17):2777-84. doi: 10.1021/acs.biochem.5b00217. Epub 2015 Apr 23.

PMID:
25875527
41.

PAX5 is a tumor suppressor in mouse mutagenesis models of acute lymphoblastic leukemia.

Dang J, Wei L, de Ridder J, Su X, Rust AG, Roberts KG, Payne-Turner D, Cheng J, Ma J, Qu C, Wu G, Song G, Huether RG, Schulman B, Janke L, Zhang J, Downing JR, van der Weyden L, Adams DJ, Mullighan CG.

Blood. 2015 Jun 4;125(23):3609-17. doi: 10.1182/blood-2015-02-626127. Epub 2015 Apr 8.

42.

Mitigation of acute kidney injury by cell-cycle inhibitors that suppress both CDK4/6 and OCT2 functions.

Pabla N, Gibson AA, Buege M, Ong SS, Li L, Hu S, Du G, Sprowl JA, Vasilyeva A, Janke LJ, Schlatter E, Chen T, Ciarimboli G, Sparreboom A.

Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5231-6. doi: 10.1073/pnas.1424313112. Epub 2015 Apr 6.

43.

Tissue-specific differences in the development of insulin resistance in a mouse model for type 1 diabetes.

Jelenik T, Séquaris G, Kaul K, Ouwens DM, Phielix E, Kotzka J, Knebel B, Weiß J, Reinbeck AL, Janke L, Nowotny P, Partke HJ, Zhang D, Shulman GI, Szendroedi J, Roden M.

Diabetes. 2014 Nov;63(11):3856-67. doi: 10.2337/db13-1794. Epub 2014 Jun 10.

44.

Cisplatin-induced renal injury is independently mediated by OCT2 and p53.

Sprowl JA, Lancaster CS, Pabla N, Hermann E, Kosloske AM, Gibson AA, Li L, Zeeh D, Schlatter E, Janke LJ, Ciarimboli G, Sparreboom A.

Clin Cancer Res. 2014 Aug 1;20(15):4026-35. doi: 10.1158/1078-0432.CCR-14-0319. Epub 2014 Jun 10.

45.

RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3.

Dillon CP, Weinlich R, Rodriguez DA, Cripps JG, Quarato G, Gurung P, Verbist KC, Brewer TL, Llambi F, Gong YN, Janke LJ, Kelliher MA, Kanneganti TD, Green DR.

Cell. 2014 May 22;157(5):1189-202. doi: 10.1016/j.cell.2014.04.018. Epub 2014 May 8.

46.

Host thiopurine methyltransferase status affects mercaptopurine antileukemic effectiveness in a murine model.

Ramsey LB, Janke LJ, Edick MJ, Cheng C, Williams RT, Sherr CJ, Evans WE, Relling MV.

Pharmacogenet Genomics. 2014 May;24(5):263-71. doi: 10.1097/FPC.0000000000000044.

47.

Interleukin-7 receptor mutants initiate early T cell precursor leukemia in murine thymocyte progenitors with multipotent potential.

Treanor LM, Zhou S, Janke L, Churchman ML, Ma Z, Lu T, Chen SC, Mullighan CG, Sorrentino BP.

J Exp Med. 2014 Apr 7;211(4):701-13. doi: 10.1084/jem.20122727. Epub 2014 Mar 31.

48.

Tumor-derived inducible heat-shock protein 70 (HSP70) is an essential component of anti-tumor immunity.

Dodd K, Nance S, Quezada M, Janke L, Morrison JB, Williams RT, Beere HM.

Oncogene. 2015 Mar 5;34(10):1312-22. doi: 10.1038/onc.2014.63. Epub 2014 Mar 24.

49.

Development and application of a methodology for a clean development mechanism to avoid methane emissions in closed landfills.

Janke L, Lima AO, Millet M, Radetski CM.

Environ Technol. 2013 Sep-Oct;34(17-20):2607-16.

PMID:
24527622
50.

Microsporogenesis in Paspalum conspersum Schrad. (Virgata group) with different ploidy levels.

Janke L, Souza FH, Valls JF, Pagliarini MS.

Genet Mol Res. 2013 Oct 24;12(4):4948-57. doi: 10.4238/2013.October.24.6.

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