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Items: 11

1.

Structure-Function Studies on IMD-0354 Identifies Highly Active Colistin Adjuvants.

Nemeth AM, Basak AK, Weig AW, Marrujo SA, Barker WT, Jania LA, Hendricks TA, Sullivan AE, O'Connor PM, Melander RJ, Koller BH, Melander C.

ChemMedChem. 2019 Nov 22. doi: 10.1002/cmdc.201900560. [Epub ahead of print]

PMID:
31756025
2.

Beyond detoxification: Pleiotropic functions of multiple glutathione S-transferase isoforms protect mice against a toxic electrophile.

Behrens KA, Jania LA, Snouwaert JN, Nguyen M, Moy SS, Tikunov AP, Macdonald JM, Koller BH.

PLoS One. 2019 Nov 20;14(11):e0225449. doi: 10.1371/journal.pone.0225449. eCollection 2019.

3.

Repurposing Eukaryotic Kinase Inhibitors as Colistin Adjuvants in Gram-Negative Bacteria.

Barker WT, Nemeth AM, Brackett SM, Basak AK, Chandler CE, Jania LA, Zuercher WJ, Melander RJ, Koller BH, Ernst RK, Melander C.

ACS Infect Dis. 2019 Oct 11;5(10):1764-1771. doi: 10.1021/acsinfecdis.9b00212. Epub 2019 Sep 4.

PMID:
31434474
4.

Second-Generation Tryptamine Derivatives Potently Sensitize Colistin Resistant Bacteria to Colistin.

Minrovic BM, Hubble VB, Barker WT, Jania LA, Melander RJ, Koller BH, Melander C.

ACS Med Chem Lett. 2019 Apr 17;10(5):828-833. doi: 10.1021/acsmedchemlett.9b00135. eCollection 2019 May 9.

PMID:
31098007
5.

Prostaglandin E(2) produced by the lung augments the effector phase of allergic inflammation.

Church RJ, Jania LA, Koller BH.

J Immunol. 2012 Apr 15;188(8):4093-102. doi: 10.4049/jimmunol.1101873. Epub 2012 Mar 12.

6.

ONZIN deficiency attenuates contact hypersensitivity responses in mice.

Ledford JG, Kovarova M, Jania LA, Nguyen M, Koller BH.

Immunol Cell Biol. 2012 Aug;90(7):733-42. doi: 10.1038/icb.2011.107. Epub 2012 Jan 17.

7.

Microsomal prostaglandin E synthase-2 is not essential for in vivo prostaglandin E2 biosynthesis.

Jania LA, Chandrasekharan S, Backlund MG, Foley NA, Snouwaert J, Wang IM, Clark P, Audoly LP, Koller BH.

Prostaglandins Other Lipid Mediat. 2009 Apr;88(3-4):73-81. doi: 10.1016/j.prostaglandins.2008.10.003. Epub 2008 Nov 1.

8.

Francisella tularensis-infected macrophages release prostaglandin E2 that blocks T cell proliferation and promotes a Th2-like response.

Woolard MD, Wilson JE, Hensley LL, Jania LA, Kawula TH, Drake JR, Frelinger JA.

J Immunol. 2007 Feb 15;178(4):2065-74.

9.

Expression and function of NPSR1/GPRA in the lung before and after induction of asthma-like disease.

Allen IC, Pace AJ, Jania LA, Ledford JG, Latour AM, Snouwaert JN, Bernier V, Stocco R, Therien AG, Koller BH.

Am J Physiol Lung Cell Mol Physiol. 2006 Nov;291(5):L1005-17. Epub 2006 Jul 7.

10.

COX-2-derived prostacyclin protects against bleomycin-induced pulmonary fibrosis.

Lovgren AK, Jania LA, Hartney JM, Parsons KK, Audoly LP, Fitzgerald GA, Tilley SL, Koller BH.

Am J Physiol Lung Cell Mol Physiol. 2006 Aug;291(2):L144-56. Epub 2006 Feb 10.

11.

Prostaglandin E2 protects lower airways against bronchoconstriction.

Hartney JM, Coggins KG, Tilley SL, Jania LA, Lovgren AK, Audoly LP, Koller BH.

Am J Physiol Lung Cell Mol Physiol. 2006 Jan;290(1):L105-13. Epub 2005 Aug 19.

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