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Items: 1 to 50 of 113

1.

"Interrogating the grainyhead-like 2 (Grhl2) genomic locus identifies an enhancer element that regulates palatogenesis in mouse".

de Vries M, Carpinelli M, Rutland E, Hatzipantelis A, Partridge D, Auden A, Anderson PJ, De Groef B, Wu H, Osterwalder M, Visel A, Jane SM, Dworkin S.

Dev Biol. 2019 Nov 26. pii: S0012-1606(19)30607-4. doi: 10.1016/j.ydbio.2019.11.015. [Epub ahead of print]

PMID:
31782997
2.

Loss of GRHL3 leads to TARC/CCL17-mediated keratinocyte proliferation in the epidermis.

Goldie SJ, Cottle DL, Tan FH, Roslan S, Srivastava S, Brady R, Partridge DD, Auden A, Smyth IM, Jane SM, Dworkin S, Darido C.

Cell Death Dis. 2018 Oct 19;9(11):1072. doi: 10.1038/s41419-018-0901-6.

3.

Lung morphogenesis is orchestrated through Grainyhead-like 2 (Grhl2) transcriptional programs.

Kersbergen A, Best SA, Dworkin S, Ah-Cann C, de Vries ME, Asselin-Labat ML, Ritchie ME, Jane SM, Sutherland KD.

Dev Biol. 2018 Nov 1;443(1):1-9. doi: 10.1016/j.ydbio.2018.09.002. Epub 2018 Sep 5.

4.

Restricted cell cycle is essential for clonal evolution and therapeutic resistance of pre-leukemic stem cells.

Tremblay CS, Saw J, Chiu SK, Wong NC, Tsyganov K, Ghotb S, Graham AN, Yan F, Guirguis AA, Sonderegger SE, Lee N, Kalitsis P, Reynolds J, Ting SB, Powell DR, Jane SM, Curtis DJ.

Nat Commun. 2018 Aug 30;9(1):3535. doi: 10.1038/s41467-018-06021-7.

5.

Characterization of Tfrc-mutant mice with microcytic phenotypes.

Conway AJ, Brown FC, Rank G, Kile BT, Morton CJ, Jane SM, Curtis DJ.

Blood Adv. 2018 Aug 14;2(15):1914-1922. doi: 10.1182/bloodadvances.2018018820.

6.

Bone marrow transplantation corrects haemolytic anaemia in a novel ENU mutagenesis mouse model of TPI deficiency.

Conway AJ, Brown FC, Hortle EJ, Burgio G, Foote SJ, Morton CJ, Jane SM, Curtis DJ.

Dis Model Mech. 2018 May 21;11(5). pii: dmm034678. doi: 10.1242/dmm.034678.

7.

Mis-expression of grainyhead-like transcription factors in zebrafish leads to defects in enveloping layer (EVL) integrity, cellular morphogenesis and axial extension.

Miles LB, Darido C, Kaslin J, Heath JK, Jane SM, Dworkin S.

Sci Rep. 2017 Dec 14;7(1):17607. doi: 10.1038/s41598-017-17898-7.

8.

Stage-dependent therapeutic efficacy in PI3K/mTOR-driven squamous cell carcinoma of the skin.

Darido C, Georgy SR, Cullinane C, Partridge DD, Walker R, Srivastava S, Roslan S, Carpinelli MR, Dworkin S, Pearson RB, Jane SM.

Cell Death Differ. 2018 Jun;25(6):1146-1159. doi: 10.1038/s41418-017-0032-0. Epub 2017 Dec 13.

9.

Grainyhead-like Transcription Factors in Craniofacial Development.

Carpinelli MR, de Vries ME, Jane SM, Dworkin S.

J Dent Res. 2017 Oct;96(11):1200-1209. doi: 10.1177/0022034517719264. Epub 2017 Jul 11. Review.

PMID:
28697314
10.

A mouse model of hereditary coproporphyria identified in an ENU mutagenesis screen.

Conway AJ, Brown FC, Fullinfaw RO, Kile BT, Jane SM, Curtis DJ.

Dis Model Mech. 2017 Aug 1;10(8):1005-1013. doi: 10.1242/dmm.029116. Epub 2017 Jun 9.

11.

Loss of Dynamin 2 GTPase function results in microcytic anaemia.

Brown FC, Collett M, Tremblay CS, Rank G, De Camilli P, Booth CJ, Bitoun M, Robinson PJ, Kile BT, Jane SM, Curtis DJ.

Br J Haematol. 2017 Aug;178(4):616-628. doi: 10.1111/bjh.14709. Epub 2017 May 3.

PMID:
28466468
12.

Grainyhead-like 3 (Grhl3) deficiency in brain leads to altered locomotor activity and decreased anxiety-like behaviors in aged mice.

Dworkin S, Auden A, Partridge DD, Daglas M, Medcalf RL, Mantamadiotis T, Georgy SR, Darido C, Jane SM, Ting SB.

Dev Neurobiol. 2017 Jun;77(6):775-788. doi: 10.1002/dneu.22469. Epub 2017 Feb 3.

13.

The role of barrier genes in epidermal malignancy.

Darido C, Georgy SR, Jane SM.

Oncogene. 2016 Nov 3;35(44):5705-5712. doi: 10.1038/onc.2016.84. Epub 2016 Apr 4. Review.

PMID:
27041586
14.

Effects of high and low sodium diet on blood pressure and heart rate in mice lacking the functional grainyhead-like 1 gene.

Walkowska A, Pawlak M, Jane SM, Kompanowska-Jezierska E, Wilanowski T.

Physiol Res. 2017 Mar 31;66(1):163-165. Epub 2016 Oct 26.

15.
16.

Loss-of-function mutations of Dynamin 2 promote T-ALL by enhancing IL-7 signalling.

Tremblay CS, Brown FC, Collett M, Saw J, Chiu SK, Sonderegger SE, Lucas SE, Alserihi R, Chau N, Toribio ML, McCormack MP, Chircop M, Robinson PJ, Jane SM, Curtis DJ.

Leukemia. 2016 Oct;30(10):1993-2001. doi: 10.1038/leu.2016.100. Epub 2016 Apr 27.

PMID:
27118408
17.

Two Ancient Gene Families Are Critical for Maintenance of the Mammalian Skin Barrier in Postnatal Life.

Cangkrama M, Darido C, Georgy SR, Partridge D, Auden A, Srivastava S, Wilanowski T, Jane SM.

J Invest Dermatol. 2016 Jul;136(7):1438-1448. doi: 10.1016/j.jid.2016.02.806. Epub 2016 Mar 11.

18.

ε-globin expression is regulated by SUV4-20h1.

Wang Y, Rank G, Li Z, Wang Y, Ju J, Nuber A, Wu Y, Liu M, Nie M, Huang F, Cerruti L, Ma C, Tan R, Schotta G, Jane SM, Zeng CK, Zhao Q.

Haematologica. 2016 May;101(5):e168-72. doi: 10.3324/haematol.2015.139980. Epub 2016 Jan 22. No abstract available.

19.

Activation of the erythroid K-Cl cotransporter Kcc1 enhances sickle cell disease pathology in a humanized mouse model.

Brown FC, Conway AJ, Cerruti L, Collinge JE, McLean C, Wiley JS, Kile BT, Jane SM, Curtis DJ.

Blood. 2015 Dec 24;126(26):2863-70. doi: 10.1182/blood-2014-10-609362. Epub 2015 Oct 8.

PMID:
26450986
20.

Identification of a Novel Proto-oncogenic Network in Head and Neck Squamous Cell Carcinoma.

Georgy SR, Cangkrama M, Srivastava S, Partridge D, Auden A, Dworkin S, McLean CA, Jane SM, Darido C.

J Natl Cancer Inst. 2015 Jun 10;107(9). pii: djv152. doi: 10.1093/jnci/djv152. Print 2015 Sep.

21.

Consequences of the loss of the Grainyhead-like 1 gene for renal gene expression, regulation of blood pressure and heart rate in a mouse model.

Pawlak M, Walkowska A, Mlącki M, Pistolic J, Wrzesiński T, Benes V, Jane SM, Wesoły J, Kompanowska-Jezierska E, Wilanowski T.

Acta Biochim Pol. 2015;62(2):287-96. doi: 10.18388/abp.2015_1001. Epub 2015 Apr 21.

22.

Sorafenib priming may augment salvage chemotherapy in relapsed and refractory FLT3-ITD-positive acute myeloid leukemia.

Cummins KD, Jane SM, Ninkovic S, Bazargan A, Filshie R, Sutrave G, Hertzberg M, Scott A, Lane S, Yannakou CK, Ritchie D, D'Rozario J, Black J, Bavishi K, Wei A.

Blood Cancer J. 2014 Aug 8;4:e237. doi: 10.1038/bcj.2014.59. No abstract available. Erratum in: Blood Cancer J. 2014;4:e246. Nikovic, S [corrected to Ninkovic, S].

23.

Human fetal globin gene expression is regulated by LYAR.

Ju J, Wang Y, Liu R, Zhang Y, Xu Z, Wang Y, Wu Y, Liu M, Cerruti L, Zou F, Ma C, Fang M, Tan R, Jane SM, Zhao Q.

Nucleic Acids Res. 2014 Sep;42(15):9740-52. doi: 10.1093/nar/gku718. Epub 2014 Aug 4.

24.

Grainyhead-like 3 regulation of endothelin-1 in the pharyngeal endoderm is critical for growth and development of the craniofacial skeleton.

Dworkin S, Simkin J, Darido C, Partridge DD, Georgy SR, Caddy J, Wilanowski T, Lieschke GJ, Doggett K, Heath JK, Jane SM.

Mech Dev. 2014 Aug;133:77-90. doi: 10.1016/j.mod.2014.05.005. Epub 2014 Jun 7.

25.

Loss of Grainy head-like 1 is associated with disruption of the epidermal barrier and squamous cell carcinoma of the skin.

Mlacki M, Darido C, Jane SM, Wilanowski T.

PLoS One. 2014 Feb 20;9(2):e89247. doi: 10.1371/journal.pone.0089247. eCollection 2014.

26.

Golgi Feels Its Own Wound.

Darido C, Jane SM.

Adv Wound Care (New Rochelle). 2013 Apr;2(3):87-92. Review.

27.

Immune-mediated cytopenias in human immunodeficiency virus: the first reported case of idiopathic aplastic anaemia successfully treated with immunosuppression.

Hapgood G, Hoy JF, Morrissey CO, Jane SM.

Intern Med J. 2013 Apr;43(4):452-5. doi: 10.1111/imj.12087. Review.

PMID:
23551309
28.

Induction of human fetal hemoglobin expression by adenosine-2',3'-dialdehyde.

He Y, Rank G, Zhang M, Ju J, Liu R, Xu Z, Brown F, Cerruti L, Ma C, Tan R, Jane SM, Zhao Q.

J Transl Med. 2013 Jan 14;11:14. doi: 10.1186/1479-5876-11-14.

29.

Novel mechanisms that pattern and shape the midbrain-hindbrain boundary.

Dworkin S, Jane SM.

Cell Mol Life Sci. 2013 Sep;70(18):3365-74. doi: 10.1007/s00018-012-1240-x. Epub 2013 Jan 10. Review.

PMID:
23307071
30.

Regulation of delta-aminolevulinic acid dehydratase by krüppel-like factor 1.

Desgardin AD, Abramova T, Rosanwo TO, Kartha S, Shim EH, Jane SM, Cunningham JM.

PLoS One. 2012;7(10):e46482. doi: 10.1371/journal.pone.0046482. Epub 2012 Oct 3.

31.

ENU mutagenesis identifies the first mouse mutants reproducing human β-thalassemia at the genomic level.

Brown FC, Scott N, Rank G, Collinge JE, Vadolas J, Vickaryous N, Whitelaw N, Whitelaw E, Kile BT, Jane SM, Curtis DJ.

Blood Cells Mol Dis. 2013 Feb;50(2):86-92. doi: 10.1016/j.bcmd.2012.09.004. Epub 2012 Oct 2.

PMID:
23040355
32.

Inhibition of apoptosis by BCL2 prevents leukemic transformation of a murine myelodysplastic syndrome.

Slape CI, Saw J, Jowett JB, Aplan PD, Strasser A, Jane SM, Curtis DJ.

Blood. 2012 Sep 20;120(12):2475-83. Epub 2012 Jul 31.

33.

The role of WDR5 in silencing human fetal globin gene expression.

Xu Z, He Y, Ju J, Rank G, Cerruti L, Ma C, Simpson RJ, Moritz RL, Jane SM, Zhao Q.

Haematologica. 2012 Nov;97(11):1632-40. doi: 10.3324/haematol.2012.061937. Epub 2012 Jun 11.

34.

Midbrain-hindbrain boundary patterning and morphogenesis are regulated by diverse grainy head-like 2-dependent pathways.

Dworkin S, Darido C, Georgy SR, Wilanowski T, Srivastava S, Ellett F, Pase L, Han Y, Meng A, Heath JK, Lieschke GJ, Jane SM.

Development. 2012 Feb;139(3):525-36. doi: 10.1242/dev.066522.

35.

Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis.

Darido C, Georgy SR, Wilanowski T, Dworkin S, Auden A, Zhao Q, Rank G, Srivastava S, Finlay MJ, Papenfuss AT, Pandolfi PP, Pearson RB, Jane SM.

Cancer Cell. 2011 Nov 15;20(5):635-48. doi: 10.1016/j.ccr.2011.10.014.

36.

The planar cell polarity pathway in vertebrate epidermal development, homeostasis and repair.

Dworkin S, Jane SM, Darido C.

Organogenesis. 2011 Jul-Sep;7(3):202-8. doi: 10.4161/org.7.3.18431. Epub 2011 Jul 1.

37.

Grhl3 and GEF19 in the front rho.

Darido C, Jane SM.

Small GTPases. 2010 Sep;1(2):104-107.

38.

An ENU-induced mouse mutant of SHIP1 reveals a critical role of the stem cell isoform for suppression of macrophage activation.

Nguyen NY, Maxwell MJ, Ooms LM, Davies EM, Hilton AA, Collinge JE, Hilton DJ, Kile BT, Mitchell CA, Hibbs ML, Jane SM, Curtis DJ.

Blood. 2011 May 19;117(20):5362-71. doi: 10.1182/blood-2011-01-331041. Epub 2011 Mar 18.

PMID:
21421839
39.

The unique and cooperative roles of the Grainy head-like transcription factors in epidermal development reflect unexpected target gene specificity.

Boglev Y, Wilanowski T, Caddy J, Parekh V, Auden A, Darido C, Hislop NR, Cangkrama M, Ting SB, Jane SM.

Dev Biol. 2011 Jan 15;349(2):512-22. doi: 10.1016/j.ydbio.2010.11.011. Epub 2010 Nov 21.

40.

Regional neural tube closure defined by the Grainy head-like transcription factors.

Rifat Y, Parekh V, Wilanowski T, Hislop NR, Auden A, Ting SB, Cunningham JM, Jane SM.

Dev Biol. 2010 Sep 15;345(2):237-45. doi: 10.1016/j.ydbio.2010.07.017. Epub 2010 Jul 21.

41.

Epidermal wound repair is regulated by the planar cell polarity signaling pathway.

Caddy J, Wilanowski T, Darido C, Dworkin S, Ting SB, Zhao Q, Rank G, Auden A, Srivastava S, Papenfuss TA, Murdoch JN, Humbert PO, Parekh V, Boulos N, Weber T, Zuo J, Cunningham JM, Jane SM.

Dev Cell. 2010 Jul 20;19(1):138-47. doi: 10.1016/j.devcel.2010.06.008. Erratum in: Dev Cell. 2010 Aug 17;19(2):353. Parekh, Vishwas [added].

42.

Identification of a PRMT5-dependent repressor complex linked to silencing of human fetal globin gene expression.

Rank G, Cerruti L, Simpson RJ, Moritz RL, Jane SM, Zhao Q.

Blood. 2010 Sep 2;116(9):1585-92. doi: 10.1182/blood-2009-10-251116. Epub 2010 May 21.

43.

The TAL1/SCL transcription factor regulates cell cycle progression and proliferation in differentiating murine bone marrow monocyte precursors.

Dey S, Curtis DJ, Jane SM, Brandt SJ.

Mol Cell Biol. 2010 May;30(9):2181-92. doi: 10.1128/MCB.01441-09. Epub 2010 Mar 1.

44.

The Lmo2 oncogene initiates leukemia in mice by inducing thymocyte self-renewal.

McCormack MP, Young LF, Vasudevan S, de Graaf CA, Codrington R, Rabbitts TH, Jane SM, Curtis DJ.

Science. 2010 Feb 12;327(5967):879-83. doi: 10.1126/science.1182378. Epub 2010 Jan 21.

45.

The Hedgehog receptor Patched1 regulates myeloid and lymphoid progenitors by distinct cell-extrinsic mechanisms.

Siggins SL, Nguyen NY, McCormack MP, Vasudevan S, Villani R, Jane SM, Wainwright BJ, Curtis DJ.

Blood. 2009 Jul 30;114(5):995-1004. doi: 10.1182/blood-2009-03-208330. Epub 2009 May 29.

PMID:
19483124
46.

PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing.

Zhao Q, Rank G, Tan YT, Li H, Moritz RL, Simpson RJ, Cerruti L, Curtis DJ, Patel DJ, Allis CD, Cunningham JM, Jane SM.

Nat Struct Mol Biol. 2009 Mar;16(3):304-311. doi: 10.1038/nsmb.1568. Epub 2009 Feb 22.

47.

Novel roles for erythroid Ankyrin-1 revealed through an ENU-induced null mouse mutant.

Rank G, Sutton R, Marshall V, Lundie RJ, Caddy J, Romeo T, Fernandez K, McCormack MP, Cooke BM, Foote SJ, Crabb BS, Curtis DJ, Hilton DJ, Kile BT, Jane SM.

Blood. 2009 Apr 2;113(14):3352-62. doi: 10.1182/blood-2008-08-172841. Epub 2009 Jan 28.

48.

Grhl3 and Lmo4 play coordinate roles in epidermal migration.

Hislop NR, Caddy J, Ting SB, Auden A, Vasudevan S, King SL, Lindeman GJ, Visvader JE, Cunningham JM, Jane SM.

Dev Biol. 2008 Sep 1;321(1):263-72. doi: 10.1016/j.ydbio.2008.06.026. Epub 2008 Jun 26.

49.

Perturbed desmosomal cadherin expression in grainy head-like 1-null mice.

Wilanowski T, Caddy J, Ting SB, Hislop NR, Cerruti L, Auden A, Zhao LL, Asquith S, Ellis S, Sinclair R, Cunningham JM, Jane SM.

EMBO J. 2008 Mar 19;27(6):886-97. doi: 10.1038/emboj.2008.24. Epub 2008 Feb 21.

50.

Aberrant mast-cell differentiation in mice lacking the stem-cell leukemia gene.

Salmon JM, Slater NJ, Hall MA, McCormack MP, Nutt SL, Jane SM, Curtis DJ.

Blood. 2007 Nov 15;110(10):3573-81. Epub 2007 Jul 20.

PMID:
17644741

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