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Pressure overload induced right ventricular remodeling is not attenuated by the anti-fibrotic agent pirfenidone.

Andersen S, Birkmose Axelsen J, Ringgaard S, Randel Nyengaard J, Holm Nielsen S, Genovese F, Asser Karsdal M, Adler Hyldebrandt J, Brandt Sørensen C, de Man FS, Jan Bogaard H, Erik Nielsen-Kudsk J, Andersen A.

Pulm Circ. 2019 Apr-Jun;9(2):2045894019848659. doi: 10.1177/2045894019848659.


Treatment response in patients with idiopathic pulmonary arterial hypertension and a severely reduced diffusion capacity.

van der Bruggen CE, Spruijt OA, Nossent EJ, Trip P, Marcus JT, de Man FS, Jan Bogaard H, Noordegraaf AV.

Pulm Circ. 2017 Mar 13;7(1):137-144. doi: 10.1086/690016. eCollection 2017 Mar.


Reversal of right ventricular remodeling by dichloroacetate is related to inhibition of mitochondria-dependent apoptosis.

Sun XQ, Zhang R, Zhang HD, Yuan P, Wang XJ, Zhao QH, Wang L, Jiang R, Jan Bogaard H, Jing ZC.

Hypertens Res. 2016 May;39(5):302-11. doi: 10.1038/hr.2015.153. Epub 2016 Jan 14.


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