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Items: 1 to 50 of 115

1.

Xenoprotein engineering via synthetic libraries.

Gates ZP, Vinogradov AA, Quartararo AJ, Bandyopadhyay A, Choo ZN, Evans ED, Halloran KH, Mijalis AJ, Mong SK, Simon MD, Standley EA, Styduhar ED, Tasker SZ, Touti F, Weber JM, Wilson JL, Jamison TF, Pentelute BL.

Proc Natl Acad Sci U S A. 2018 Jun 5;115(23):E5298-E5306. doi: 10.1073/pnas.1722633115. Epub 2018 May 21.

PMID:
29784819
2.

Synthesis of Highly Substituted 2-Arylindoles via Copper-Catalyzed Coupling of Isocyanides and Arylboronic Acids.

Heckman LM, He Z, Jamison TF.

Org Lett. 2018 Jun 1;20(11):3263-3267. doi: 10.1021/acs.orglett.8b01132. Epub 2018 May 15.

PMID:
29761699
3.

7-Step Flow Synthesis of the HIV Integrase Inhibitor Dolutegravir.

Ziegler RE, Desai BK, Jee JA, Gupton BF, Roper TD, Jamison TF.

Angew Chem Int Ed Engl. 2018 Jun 11;57(24):7181-7185. doi: 10.1002/anie.201802256. Epub 2018 May 14.

PMID:
29756689
4.

Synthesis of the ABC framework of tamulamides A and B.

Kelley EH, Jamison TF.

Bioorg Med Chem. 2018 Apr 22. pii: S0968-0896(18)30431-0. doi: 10.1016/j.bmc.2018.04.046. [Epub ahead of print]

PMID:
29729986
5.

Studies toward brevisulcenal F via convergent strategies for marine ladder polyether synthesis.

Katcher M, Jamison TF.

Tetrahedron. 2018 Mar 15;74(11):1111-1122. doi: 10.1016/j.tet.2018.01.039. Epub 2018 Feb 2.

PMID:
29479119
6.

Ni-Catalyzed Electrochemical Decarboxylative C-C Couplings in Batch and Continuous Flow.

Li H, Breen CP, Seo H, Jamison TF, Fang YQ, Bio MM.

Org Lett. 2018 Mar 2;20(5):1338-1341. doi: 10.1021/acs.orglett.8b00070. Epub 2018 Feb 12.

7.

Advanced Continuous Flow Platform for On-Demand Pharmaceutical Manufacturing.

Zhang P, Weeranoppanant N, Thomas DA, Tahara K, Stelzer T, Russell MG, O'Mahony M, Myerson AS, Lin H, Kelly LP, Jensen KF, Jamison TF, Dai C, Cui Y, Briggs N, Beingessner RL, Adamo A.

Chemistry. 2018 Feb 21;24(11):2776-2784. doi: 10.1002/chem.201706004. Epub 2018 Jan 31.

PMID:
29385292
8.

The assembly and use of continuous flow systems for chemical synthesis.

Britton J, Jamison TF.

Nat Protoc. 2017 Nov;12(11):2423-2446. doi: 10.1038/nprot.2017.102. Epub 2017 Oct 26.

PMID:
29072707
9.

Direct β-Selective Hydrocarboxylation of Styrenes with CO2 Enabled by Continuous Flow Photoredox Catalysis.

Seo H, Liu A, Jamison TF.

J Am Chem Soc. 2017 Oct 11;139(40):13969-13972. doi: 10.1021/jacs.7b05942. Epub 2017 Sep 27.

PMID:
28953365
10.

Synthesis and Utilization of Nitroalkyne Equivalents in Batch and Continuous Flow.

Morse PD, Jamison TF.

Angew Chem Int Ed Engl. 2017 Nov 6;56(45):13999-14002. doi: 10.1002/anie.201706157. Epub 2017 Oct 4.

11.

A Rapid Total Synthesis of Ciprofloxacin Hydrochloride in Continuous Flow.

Lin H, Dai C, Jamison TF, Jensen KF.

Angew Chem Int Ed Engl. 2017 Jul 17;56(30):8870-8873. doi: 10.1002/anie.201703812. Epub 2017 Jun 20.

PMID:
28561939
12.

A Unified Continuous Flow Assembly-Line Synthesis of Highly Substituted Pyrazoles and Pyrazolines.

Britton J, Jamison TF.

Angew Chem Int Ed Engl. 2017 Jul 17;56(30):8823-8827. doi: 10.1002/anie.201704529. Epub 2017 Jun 20.

PMID:
28544160
13.

Photoredox activation of carbon dioxide for amino acid synthesis in continuous flow.

Seo H, Katcher MH, Jamison TF.

Nat Chem. 2017 May;9(5):453-456. doi: 10.1038/nchem.2690. Epub 2016 Dec 26.

14.

Minimizing E-factor in the continuous-flow synthesis of diazepam and atropine.

Bédard AC, Longstreet AR, Britton J, Wang Y, Moriguchi H, Hicklin RW, Green WH, Jamison TF.

Bioorg Med Chem. 2017 Dec 1;25(23):6233-6241. doi: 10.1016/j.bmc.2017.02.002. Epub 2017 Feb 4.

PMID:
28284869
15.

Towards More Efficient, Greener Syntheses through Flow Chemistry.

Lummiss JAM, Morse PD, Beingessner RL, Jamison TF.

Chem Rec. 2017 Jul;17(7):667-680. doi: 10.1002/tcr.201600139. Epub 2017 Feb 28. Review.

PMID:
28245339
16.

Photoredox Activation of SF6 for Fluorination.

McTeague TA, Jamison TF.

Angew Chem Int Ed Engl. 2016 Nov 21;55(48):15072-15075. doi: 10.1002/anie.201608792. Epub 2016 Nov 4.

PMID:
27813242
17.

On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system.

Adamo A, Beingessner RL, Behnam M, Chen J, Jamison TF, Jensen KF, Monbaliu JC, Myerson AS, Revalor EM, Snead DR, Stelzer T, Weeranoppanant N, Wong SY, Zhang P.

Science. 2016 Apr 1;352(6281):61-7. doi: 10.1126/science.aaf1337.

18.

Stereoselective Formation of Fully Substituted Ketone Enolates.

Haimov E, Nairoukh Z, Shterenberg A, Berkovitz T, Jamison TF, Marek I.

Angew Chem Int Ed Engl. 2016 Apr 25;55(18):5517-20. doi: 10.1002/anie.201601883. Epub 2016 Mar 29.

PMID:
27027778
19.

Iterative exponential growth of stereo- and sequence-controlled polymers.

Barnes JC, Ehrlich DJ, Gao AX, Leibfarth FA, Jiang Y, Zhou E, Jamison TF, Johnson JA.

Nat Chem. 2015 Oct;7(10):810-5. doi: 10.1038/nchem.2346. Epub 2015 Sep 7.

PMID:
26391080
20.

Scalable synthesis of sequence-defined, unimolecular macromolecules by Flow-IEG.

Leibfarth FA, Johnson JA, Jamison TF.

Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):10617-22. doi: 10.1073/pnas.1508599112. Epub 2015 Aug 12.

21.

Highly Regioselective Indoline Synthesis under Nickel/Photoredox Dual Catalysis.

Tasker SZ, Jamison TF.

J Am Chem Soc. 2015 Aug 5;137(30):9531-4. doi: 10.1021/jacs.5b05597. Epub 2015 Jul 21.

22.

Rhodium-catalyzed endo-selective epoxide-opening cascades: formal synthesis of (-)-brevisin.

Armbrust KW, Beaver MG, Jamison TF.

J Am Chem Soc. 2015 Jun 3;137(21):6941-6. doi: 10.1021/jacs.5b03570. Epub 2015 May 18.

23.

Nickel Catalysis: Synergy between Method Development and Total Synthesis.

Standley EA, Tasker SZ, Jensen KL, Jamison TF.

Acc Chem Res. 2015 May 19;48(5):1503-14. doi: 10.1021/acs.accounts.5b00064. Epub 2015 Apr 23.

24.

A General Strategy for the Synthesis of Enantiomerically Pure Azetidines and Aziridines through Nickel-Catalyzed Cross-Coupling.

Jensen KL, Nielsen DU, Jamison TF.

Chemistry. 2015 May 11;21(20):7379-83. doi: 10.1002/chem.201500886. Epub 2015 Mar 27.

PMID:
25820027
25.

Selective Lewis acid catalyzed assembly of phosphonomethyl ethers: three-step synthesis of tenofovir.

Ocampo CE, Lee D, Jamison TF.

Org Lett. 2015 Feb 20;17(4):820-3. doi: 10.1021/ol503612h. Epub 2015 Feb 9.

PMID:
25664399
26.

Hydroxyl-substituted ladder polyethers via selective tandem epoxidation/cyclization sequence.

Czabaniuk LC, Jamison TF.

Org Lett. 2015 Feb 20;17(4):774-7. doi: 10.1021/ol503400j. Epub 2015 Feb 3.

27.

Electrophilic amination: the case of nitrenoids.

Starkov P, Jamison TF, Marek I.

Chemistry. 2015 Mar 27;21(14):5278-300. doi: 10.1002/chem.201405779. Epub 2015 Jan 15.

PMID:
25641706
28.

A three-minute synthesis and purification of ibuprofen: pushing the limits of continuous-flow processing.

Snead DR, Jamison TF.

Angew Chem Int Ed Engl. 2015 Jan 12;54(3):983-7. doi: 10.1002/anie.201409093. Epub 2014 Dec 2.

PMID:
25470733
29.

Continuous flow synthesis of chiral amines in organic solvents: immobilization of E. coli cells containing both ω-transaminase and PLP.

Andrade LH, Kroutil W, Jamison TF.

Org Lett. 2014 Dec 5;16(23):6092-5. doi: 10.1021/ol502712v. Epub 2014 Nov 13.

PMID:
25394227
30.

Synthesis of highly functionalized polycyclic quinoxaline derivatives using visible-light photoredox catalysis.

He Z, Bae M, Wu J, Jamison TF.

Angew Chem Int Ed Engl. 2014 Dec 22;53(52):14451-5. doi: 10.1002/anie.201408522. Epub 2014 Oct 27.

PMID:
25347967
31.

Highly regioselective nickel-catalyzed cross-coupling of N-tosylaziridines and alkylzinc reagents.

Jensen KL, Standley EA, Jamison TF.

J Am Chem Soc. 2014 Aug 6;136(31):11145-52. doi: 10.1021/ja505823s. Epub 2014 Jul 23.

PMID:
25055180
32.

Continuous flow synthesis of ketones from carbon dioxide and organolithium or Grignard reagents.

Wu J, Yang X, He Z, Mao X, Hatton TA, Jamison TF.

Angew Chem Int Ed Engl. 2014 Aug 4;53(32):8416-20. doi: 10.1002/anie.201405014. Epub 2014 Jun 24.

PMID:
24961600
33.

Recent advances in homogeneous nickel catalysis.

Tasker SZ, Standley EA, Jamison TF.

Nature. 2014 May 15;509(7500):299-309. doi: 10.1038/nature13274. Review. Erratum in: Nature. 2014 Jun 5;510(7503):176.

34.

A Broadly Applicable Strategy for Entry into Homogeneous Nickel(0) Catalysts from Air-Stable Nickel(II) Complexes.

Standley EA, Smith SJ, Müller P, Jamison TF.

Organometallics. 2014 Apr 28;33(8):2012-2018. Epub 2014 Apr 16.

35.

Continuous-flow synthesis of functionalized phenols by aerobic oxidation of Grignard reagents.

He Z, Jamison TF.

Angew Chem Int Ed Engl. 2014 Mar 24;53(13):3353-7. doi: 10.1002/anie.201310572. Epub 2014 Feb 19.

PMID:
24554581
36.

Microwave assisted synthesis of cyclic carbonates from olefins with sodium bicarbonates as the C1 source.

Yang X, Wu J, Mao X, Jamison TF, Hatton TA.

Chem Commun (Camb). 2014 Mar 25;50(24):3245-8. doi: 10.1039/c4cc00252k. Epub 2014 Feb 13.

PMID:
24522755
37.

Nickel-catalyzed Mizoroki-Heck reaction of aryl sulfonates and chlorides with electronically unbiased terminal olefins: high selectivity for branched products.

Tasker SZ, Gutierrez AC, Jamison TF.

Angew Chem Int Ed Engl. 2014 Feb 10;53(7):1858-61. doi: 10.1002/anie.201308391. Epub 2014 Jan 8.

38.

Bromine-catalyzed conversion of CO2 and epoxides to cyclic carbonates under continuous flow conditions.

Kozak JA, Wu J, Su X, Simeon F, Hatton TA, Jamison TF.

J Am Chem Soc. 2013 Dec 11;135(49):18497-501. doi: 10.1021/ja4079094. Epub 2013 Nov 20.

PMID:
24256033
39.

End-to-end continuous manufacturing of pharmaceuticals: integrated synthesis, purification, and final dosage formation.

Mascia S, Heider PL, Zhang H, Lakerveld R, Benyahia B, Barton PI, Braatz RD, Cooney CL, Evans JM, Jamison TF, Jensen KF, Myerson AS, Trout BL.

Angew Chem Int Ed Engl. 2013 Nov 18;52(47):12359-63. doi: 10.1002/anie.201305429. Epub 2013 Oct 2.

PMID:
24115355
40.

Entropic factors provide unusual reactivity and selectivity in epoxide-opening reactions promoted by water.

Byers JA, Jamison TF.

Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):16724-9. doi: 10.1073/pnas.1311133110. Epub 2013 Sep 17.

41.

A reductive coupling strategy towards ripostatin A.

Schleicher KD, Jamison TF.

Beilstein J Org Chem. 2013 Jul 31;9:1533-50. doi: 10.3762/bjoc.9.175. eCollection 2013.

43.

A dioxane template for highly selective epoxy alcohol cyclizations.

Mousseau JJ, Morten CJ, Jamison TF.

Chemistry. 2013 Jul 22;19(30):10004-16. doi: 10.1002/chem.201300845. Epub 2013 Jun 17.

44.

Peptide fragment coupling using a continuous-flow photochemical rearrangement of nitrones.

Zhang Y, Blackman ML, Leduc AB, Jamison TF.

Angew Chem Int Ed Engl. 2013 Apr 8;52(15):4251-5. doi: 10.1002/anie.201300504. Epub 2013 Mar 4. No abstract available.

PMID:
23460372
45.

Hydrogen-free alkene reduction in continuous flow.

Kleinke AS, Jamison TF.

Org Lett. 2013 Feb 1;15(3):710-3. doi: 10.1021/ol400051n. Epub 2013 Jan 22.

PMID:
23339476
46.

Simplifying nickel(0) catalysis: an air-stable nickel precatalyst for the internally selective benzylation of terminal alkenes.

Standley EA, Jamison TF.

J Am Chem Soc. 2013 Jan 30;135(4):1585-92. doi: 10.1021/ja3116718. Epub 2013 Jan 14.

47.

Ask the experts: the challenges and benefits of flow chemistry to optimize drug development.

Anderson N, Gernaey KV, Jamison TF, Kircher M, Wiles C, Leadbeater NE, Sandford G, Richardson P.

Future Med Chem. 2012 Sep;4(14):1779-89. doi: 10.4155/fmc.12.106.

PMID:
23043475
48.

Continuous flow photocatalysis enhanced using an aluminum mirror: rapid and selective synthesis of 2'-deoxy and 2',3'-dideoxynucleosides.

Shen B, Bedore MW, Sniady A, Jamison TF.

Chem Commun (Camb). 2012 Aug 4;48(60):7444-6. doi: 10.1039/c2cc33356b. Epub 2012 Jun 22.

PMID:
22728875
49.

Rapid continuous synthesis of 5'-deoxyribonucleosides in flow via Brønsted acid catalyzed glycosylation.

Shen B, Jamison TF.

Org Lett. 2012 Jul 6;14(13):3348-51. doi: 10.1021/ol301324g. Epub 2012 Jun 13.

PMID:
22694250
50.

A continuous homologation of esters: an efficient telescoped reduction-olefination sequence.

Webb D, Jamison TF.

Org Lett. 2012 May 18;14(10):2465-7. doi: 10.1021/ol300722e. Epub 2012 Apr 30.

PMID:
22545983

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