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Items: 1 to 50 of 127

1.

Continuous Flow Synthesis of ACE Inhibitors From N-Substituted l-Alanine Derivatives.

Breen CP, Jamison TF.

Chemistry. 2019 Oct 18. doi: 10.1002/chem.201904400. [Epub ahead of print]

PMID:
31625640
2.

Synthesis of the EFG Framework of Tamulamides A and B.

Kelley EH, Jamison TF.

Org Lett. 2019 Oct 4;21(19):8027-8030. doi: 10.1021/acs.orglett.9b03015. Epub 2019 Sep 16.

PMID:
31523969
3.

A robotic platform for flow synthesis of organic compounds informed by AI planning.

Coley CW, Thomas DA 3rd, Lummiss JAM, Jaworski JN, Breen CP, Schultz V, Hart T, Fishman JS, Rogers L, Gao H, Hicklin RW, Plehiers PP, Byington J, Piotti JS, Green WH, Hart AJ, Jamison TF, Jensen KF.

Science. 2019 Aug 9;365(6453). pii: eaax1566. doi: 10.1126/science.aax1566.

PMID:
31395756
4.

Modular Continuous Flow Synthesis of Imatinib and Analogues.

Fu WC, Jamison TF.

Org Lett. 2019 Aug 2;21(15):6112-6116. doi: 10.1021/acs.orglett.9b02259. Epub 2019 Jul 17.

PMID:
31314541
5.

Total Synthesis of the Marine Ladder Polyether Gymnocin B.

Sittihan S, Jamison TF.

J Am Chem Soc. 2019 Jul 17;141(28):11239-11244. doi: 10.1021/jacs.9b04696. Epub 2019 Jul 8.

PMID:
31283211
6.

Ni-Catalyzed Cross-Electrophile Coupling for the Synthesis of Skipped Polyenes.

McGeough CP, Strom AE, Jamison TF.

Org Lett. 2019 May 17;21(10):3606-3609. doi: 10.1021/acs.orglett.9b01019. Epub 2019 May 2.

PMID:
31046296
7.

Seven-Step Continuous Flow Synthesis of Linezolid Without Intermediate Purification.

Russell MG, Jamison TF.

Angew Chem Int Ed Engl. 2019 Jun 3;58(23):7678-7681. doi: 10.1002/anie.201901814. Epub 2019 May 8.

PMID:
30964955
8.

A graph-convolutional neural network model for the prediction of chemical reactivity.

Coley CW, Jin W, Rogers L, Jamison TF, Jaakkola TS, Green WH, Barzilay R, Jensen KF.

Chem Sci. 2018 Nov 26;10(2):370-377. doi: 10.1039/c8sc04228d. eCollection 2019 Jan 14.

9.

Corrigendum: 7-Step Flow Synthesis of the HIV Integrase Inhibitor Dolutegravir.

Ziegler RE, Desai BK, Jee JA, Gupton BF, Roper TD, Jamison TF.

Angew Chem Int Ed Engl. 2018 Nov 12;57(46):14969. doi: 10.1002/anie.201809594. Epub 2018 Sep 16. No abstract available.

PMID:
30398024
10.

Reconfigurable system for automated optimization of diverse chemical reactions.

Bédard AC, Adamo A, Aroh KC, Russell MG, Bedermann AA, Torosian J, Yue B, Jensen KF, Jamison TF.

Science. 2018 Sep 21;361(6408):1220-1225. doi: 10.1126/science.aat0650.

PMID:
30237351
11.

Bench-Stable Nickel Precatalysts with Heck-type Activation.

Weber JM, Longstreet AR, Jamison TF.

Organometallics. 2018 Aug 27;37(16):2716-2722. doi: 10.1021/acs.organomet.8b00351. Epub 2018 Aug 9.

12.

Bench-Stable N-Heterocyclic Carbene Nickel Precatalysts for C-C and C-N Bond-Forming Reactions.

Strieth-Kalthoff F, Longstreet AR, Weber JM, Jamison TF.

ChemCatChem. 2018 Jul 9;10(13):2873-2877. doi: 10.1002/cctc.201800454. Epub 2018 May 2.

13.

Xenoprotein engineering via synthetic libraries.

Gates ZP, Vinogradov AA, Quartararo AJ, Bandyopadhyay A, Choo ZN, Evans ED, Halloran KH, Mijalis AJ, Mong SK, Simon MD, Standley EA, Styduhar ED, Tasker SZ, Touti F, Weber JM, Wilson JL, Jamison TF, Pentelute BL.

Proc Natl Acad Sci U S A. 2018 Jun 5;115(23):E5298-E5306. doi: 10.1073/pnas.1722633115. Epub 2018 May 21.

14.

Synthesis of Highly Substituted 2-Arylindoles via Copper-Catalyzed Coupling of Isocyanides and Arylboronic Acids.

Heckman LM, He Z, Jamison TF.

Org Lett. 2018 Jun 1;20(11):3263-3267. doi: 10.1021/acs.orglett.8b01132. Epub 2018 May 15.

PMID:
29761699
15.

7-Step Flow Synthesis of the HIV Integrase Inhibitor Dolutegravir.

Ziegler RE, Desai BK, Jee JA, Gupton BF, Roper TD, Jamison TF.

Angew Chem Int Ed Engl. 2018 Jun 11;57(24):7181-7185. doi: 10.1002/anie.201802256. Epub 2018 May 14. Erratum in: Angew Chem Int Ed Engl. 2018 Nov 12;57(46):14969.

16.

Synthesis of the ABC framework of tamulamides A and B.

Kelley EH, Jamison TF.

Bioorg Med Chem. 2018 Oct 15;26(19):5327-5335. doi: 10.1016/j.bmc.2018.04.046. Epub 2018 Apr 22.

17.

Studies toward brevisulcenal F via convergent strategies for marine ladder polyether synthesis.

Katcher M, Jamison TF.

Tetrahedron. 2018 Mar 15;74(11):1111-1122. doi: 10.1016/j.tet.2018.01.039. Epub 2018 Feb 2.

18.

Ni-Catalyzed Electrochemical Decarboxylative C-C Couplings in Batch and Continuous Flow.

Li H, Breen CP, Seo H, Jamison TF, Fang YQ, Bio MM.

Org Lett. 2018 Mar 2;20(5):1338-1341. doi: 10.1021/acs.orglett.8b00070. Epub 2018 Feb 12.

19.

Advanced Continuous Flow Platform for On-Demand Pharmaceutical Manufacturing.

Zhang P, Weeranoppanant N, Thomas DA, Tahara K, Stelzer T, Russell MG, O'Mahony M, Myerson AS, Lin H, Kelly LP, Jensen KF, Jamison TF, Dai C, Cui Y, Briggs N, Beingessner RL, Adamo A.

Chemistry. 2018 Feb 21;24(11):2776-2784. doi: 10.1002/chem.201706004. Epub 2018 Jan 31.

PMID:
29385292
20.

The assembly and use of continuous flow systems for chemical synthesis.

Britton J, Jamison TF.

Nat Protoc. 2017 Nov;12(11):2423-2446. doi: 10.1038/nprot.2017.102. Epub 2017 Oct 26.

PMID:
29072707
21.

Direct β-Selective Hydrocarboxylation of Styrenes with CO2 Enabled by Continuous Flow Photoredox Catalysis.

Seo H, Liu A, Jamison TF.

J Am Chem Soc. 2017 Oct 11;139(40):13969-13972. doi: 10.1021/jacs.7b05942. Epub 2017 Sep 27.

PMID:
28953365
22.

Synthesis and Utilization of Nitroalkyne Equivalents in Batch and Continuous Flow.

Morse PD, Jamison TF.

Angew Chem Int Ed Engl. 2017 Nov 6;56(45):13999-14002. doi: 10.1002/anie.201706157. Epub 2017 Oct 4.

23.

A Rapid Total Synthesis of Ciprofloxacin Hydrochloride in Continuous Flow.

Lin H, Dai C, Jamison TF, Jensen KF.

Angew Chem Int Ed Engl. 2017 Jul 17;56(30):8870-8873. doi: 10.1002/anie.201703812. Epub 2017 Jun 20.

PMID:
28561939
24.

A Unified Continuous Flow Assembly-Line Synthesis of Highly Substituted Pyrazoles and Pyrazolines.

Britton J, Jamison TF.

Angew Chem Int Ed Engl. 2017 Jul 17;56(30):8823-8827. doi: 10.1002/anie.201704529. Epub 2017 Jun 20.

PMID:
28544160
25.

Photoredox activation of carbon dioxide for amino acid synthesis in continuous flow.

Seo H, Katcher MH, Jamison TF.

Nat Chem. 2017 May;9(5):453-456. doi: 10.1038/nchem.2690. Epub 2016 Dec 26.

26.

Minimizing E-factor in the continuous-flow synthesis of diazepam and atropine.

Bédard AC, Longstreet AR, Britton J, Wang Y, Moriguchi H, Hicklin RW, Green WH, Jamison TF.

Bioorg Med Chem. 2017 Dec 1;25(23):6233-6241. doi: 10.1016/j.bmc.2017.02.002. Epub 2017 Feb 4.

PMID:
28284869
27.

Towards More Efficient, Greener Syntheses through Flow Chemistry.

Lummiss JAM, Morse PD, Beingessner RL, Jamison TF.

Chem Rec. 2017 Jul;17(7):667-680. doi: 10.1002/tcr.201600139. Epub 2017 Feb 28. Review.

PMID:
28245339
28.

Photoredox Activation of SF6 for Fluorination.

McTeague TA, Jamison TF.

Angew Chem Int Ed Engl. 2016 Nov 21;55(48):15072-15075. doi: 10.1002/anie.201608792. Epub 2016 Nov 4.

PMID:
27813242
29.

On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system.

Adamo A, Beingessner RL, Behnam M, Chen J, Jamison TF, Jensen KF, Monbaliu JC, Myerson AS, Revalor EM, Snead DR, Stelzer T, Weeranoppanant N, Wong SY, Zhang P.

Science. 2016 Apr 1;352(6281):61-7. doi: 10.1126/science.aaf1337.

30.

Stereoselective Formation of Fully Substituted Ketone Enolates.

Haimov E, Nairoukh Z, Shterenberg A, Berkovitz T, Jamison TF, Marek I.

Angew Chem Int Ed Engl. 2016 Apr 25;55(18):5517-20. doi: 10.1002/anie.201601883. Epub 2016 Mar 29.

PMID:
27027778
31.

Iterative exponential growth of stereo- and sequence-controlled polymers.

Barnes JC, Ehrlich DJ, Gao AX, Leibfarth FA, Jiang Y, Zhou E, Jamison TF, Johnson JA.

Nat Chem. 2015 Oct;7(10):810-5. doi: 10.1038/nchem.2346. Epub 2015 Sep 7.

PMID:
26391080
32.

Scalable synthesis of sequence-defined, unimolecular macromolecules by Flow-IEG.

Leibfarth FA, Johnson JA, Jamison TF.

Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):10617-22. doi: 10.1073/pnas.1508599112. Epub 2015 Aug 12.

33.

Highly Regioselective Indoline Synthesis under Nickel/Photoredox Dual Catalysis.

Tasker SZ, Jamison TF.

J Am Chem Soc. 2015 Aug 5;137(30):9531-4. doi: 10.1021/jacs.5b05597. Epub 2015 Jul 21.

34.

Rhodium-catalyzed endo-selective epoxide-opening cascades: formal synthesis of (-)-brevisin.

Armbrust KW, Beaver MG, Jamison TF.

J Am Chem Soc. 2015 Jun 3;137(21):6941-6. doi: 10.1021/jacs.5b03570. Epub 2015 May 18.

35.

Nickel Catalysis: Synergy between Method Development and Total Synthesis.

Standley EA, Tasker SZ, Jensen KL, Jamison TF.

Acc Chem Res. 2015 May 19;48(5):1503-14. doi: 10.1021/acs.accounts.5b00064. Epub 2015 Apr 23.

36.

A General Strategy for the Synthesis of Enantiomerically Pure Azetidines and Aziridines through Nickel-Catalyzed Cross-Coupling.

Jensen KL, Nielsen DU, Jamison TF.

Chemistry. 2015 May 11;21(20):7379-83. doi: 10.1002/chem.201500886. Epub 2015 Mar 27.

PMID:
25820027
37.

Selective Lewis acid catalyzed assembly of phosphonomethyl ethers: three-step synthesis of tenofovir.

Ocampo CE, Lee D, Jamison TF.

Org Lett. 2015 Feb 20;17(4):820-3. doi: 10.1021/ol503612h. Epub 2015 Feb 9.

PMID:
25664399
38.

Hydroxyl-substituted ladder polyethers via selective tandem epoxidation/cyclization sequence.

Czabaniuk LC, Jamison TF.

Org Lett. 2015 Feb 20;17(4):774-7. doi: 10.1021/ol503400j. Epub 2015 Feb 3.

39.

Electrophilic amination: the case of nitrenoids.

Starkov P, Jamison TF, Marek I.

Chemistry. 2015 Mar 27;21(14):5278-300. doi: 10.1002/chem.201405779. Epub 2015 Jan 15.

PMID:
25641706
40.

A three-minute synthesis and purification of ibuprofen: pushing the limits of continuous-flow processing.

Snead DR, Jamison TF.

Angew Chem Int Ed Engl. 2015 Jan 12;54(3):983-7. doi: 10.1002/anie.201409093. Epub 2014 Dec 2.

PMID:
25470733
41.

Continuous flow synthesis of chiral amines in organic solvents: immobilization of E. coli cells containing both ω-transaminase and PLP.

Andrade LH, Kroutil W, Jamison TF.

Org Lett. 2014 Dec 5;16(23):6092-5. doi: 10.1021/ol502712v. Epub 2014 Nov 13.

PMID:
25394227
42.

Synthesis of highly functionalized polycyclic quinoxaline derivatives using visible-light photoredox catalysis.

He Z, Bae M, Wu J, Jamison TF.

Angew Chem Int Ed Engl. 2014 Dec 22;53(52):14451-5. doi: 10.1002/anie.201408522. Epub 2014 Oct 27.

PMID:
25347967
43.

Highly regioselective nickel-catalyzed cross-coupling of N-tosylaziridines and alkylzinc reagents.

Jensen KL, Standley EA, Jamison TF.

J Am Chem Soc. 2014 Aug 6;136(31):11145-52. doi: 10.1021/ja505823s. Epub 2014 Jul 23.

PMID:
25055180
44.

Continuous flow synthesis of ketones from carbon dioxide and organolithium or Grignard reagents.

Wu J, Yang X, He Z, Mao X, Hatton TA, Jamison TF.

Angew Chem Int Ed Engl. 2014 Aug 4;53(32):8416-20. doi: 10.1002/anie.201405014. Epub 2014 Jun 24.

PMID:
24961600
45.

Recent advances in homogeneous nickel catalysis.

Tasker SZ, Standley EA, Jamison TF.

Nature. 2014 May 15;509(7500):299-309. doi: 10.1038/nature13274. Review. Erratum in: Nature. 2014 Jun 5;510(7503):176.

46.

A Broadly Applicable Strategy for Entry into Homogeneous Nickel(0) Catalysts from Air-Stable Nickel(II) Complexes.

Standley EA, Smith SJ, Müller P, Jamison TF.

Organometallics. 2014 Apr 28;33(8):2012-2018. Epub 2014 Apr 16.

47.

Continuous-flow synthesis of functionalized phenols by aerobic oxidation of Grignard reagents.

He Z, Jamison TF.

Angew Chem Int Ed Engl. 2014 Mar 24;53(13):3353-7. doi: 10.1002/anie.201310572. Epub 2014 Feb 19.

PMID:
24554581
48.

Microwave assisted synthesis of cyclic carbonates from olefins with sodium bicarbonates as the C1 source.

Yang X, Wu J, Mao X, Jamison TF, Hatton TA.

Chem Commun (Camb). 2014 Mar 25;50(24):3245-8. doi: 10.1039/c4cc00252k. Epub 2014 Feb 13.

PMID:
24522755
49.

Nickel-catalyzed Mizoroki-Heck reaction of aryl sulfonates and chlorides with electronically unbiased terminal olefins: high selectivity for branched products.

Tasker SZ, Gutierrez AC, Jamison TF.

Angew Chem Int Ed Engl. 2014 Feb 10;53(7):1858-61. doi: 10.1002/anie.201308391. Epub 2014 Jan 8.

50.

Bromine-catalyzed conversion of CO2 and epoxides to cyclic carbonates under continuous flow conditions.

Kozak JA, Wu J, Su X, Simeon F, Hatton TA, Jamison TF.

J Am Chem Soc. 2013 Dec 11;135(49):18497-501. doi: 10.1021/ja4079094. Epub 2013 Nov 20.

PMID:
24256033

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