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What a medical school chair wants from the dean.

Hromas R, Leverence R, Mramba LK, Jameson JL, Lerman C, Schwenk TL, Zimmermann EM, Good ML.

J Healthc Leadersh. 2018 May 23;10:33-44. doi: 10.2147/JHL.S158937. eCollection 2018.


Leadership Development in Medicine.

Lerman C, Jameson JL.

N Engl J Med. 2018 May 17;378(20):1862-1863. doi: 10.1056/NEJMp1801610. No abstract available.


Recommendations to Sustain the Academic Mission Ecosystem at U.S. Medical Schools.

Kerschner JE, Hedges JR, Antman K, Abraham E, Colón Negrón E, Jameson JL.

Acad Med. 2018 Jul;93(7):985-989. doi: 10.1097/ACM.0000000000002212.


A New Publishing Medium for the Endocrine Society.

Jameson JL.

J Endocr Soc. 2017 Jan 12;1(1):1-2. doi: 10.1210/js.2016-1111. eCollection 2017 Jan 1. No abstract available.


John B. Stanbury (May 15, 1915-July 6, 2015).

De Groot LJ, Dumont JE, Braverman L, Fierro Benitez R, Medeiros-Neto G, Dow E, Dumont JE, Jameson JL.

Thyroid. 2015 Nov;25(11):1177-80. doi: 10.1089/thy.2015.29008.mem. No abstract available.


Research in academic medical centers: two threats to sustainable support.

Levine AS, Alpern RJ, Andrews NC, Antman K, Balser JR, Berg JM, Davis PB, Fitz JG, Golden RN, Goldman L, Jameson JL, Lee VS, Polonsky KS, Rappley MD, Reece EA, Rothman PB, Schwinn DA, Shapiro LJ, Spiegel AM.

Sci Transl Med. 2015 May 27;7(289):289fs22. doi: 10.1126/scitranslmed.aac5200.


Precision medicine--personalized, problematic, and promising.

Jameson JL, Longo DL.

N Engl J Med. 2015 Jun 4;372(23):2229-34. doi: 10.1056/NEJMsb1503104. Epub 2015 May 27. No abstract available.


The imperative to invest in science has never been greater.

Carethers JM, Coughlin S, Diamond B, Erzurum S, Fried LP, Jameson JL, Kaushansky K, Klotman ME, Lemon S, Mitchell B, Rothman P, Sawyers C, Seidman C, Somlo S.

J Clin Invest. 2014 Sep;124(9):3680-1. doi: 10.1172/JCI77894. Epub 2014 Sep 2. No abstract available.


Endocrine Society 2014 Laureate Awards.

Gustafsson JA, Katzenellenbogen B, Jameson JL, Roth J, Melmed S, McDonnell D, Wartofsky L, Crowley WF Jr, Griz LH, Becker C, Moore DD, Drucker D, Singh N, O'Malley B.

Horm Cancer. 2014 Oct;5(5):339-55. doi: 10.1007/s12672-014-0193-y. No abstract available.


2014 Association of American Physicians Presidential Address. Disruptive innovation as a driver of science and medicine.

Jameson JL.

J Clin Invest. 2014 Jul;124(7):2822-6. doi: 10.1172/JCI77301. Epub 2014 Jul 1. No abstract available.


Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism.

Refetoff S, Bassett JH, Beck-Peccoz P, Bernal J, Brent G, Chatterjee K, De Groot LJ, Dumitrescu AM, Jameson JL, Kopp PA, Murata Y, Persani L, Samarut J, Weiss RE, Williams GR, Yen PM.

Eur Thyroid J. 2014 Mar;3(1):7-9. doi: 10.1159/000358180. Epub 2014 Mar 4. No abstract available.


Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism.

Refetoff S, Bassett JH, Beck-Peccoz P, Bernal J, Brent G, Chatterjee K, De Groot LJ, Dumitrescu AM, Jameson JL, Kopp PA, Murata Y, Persani L, Samarut J, Weiss RE, Williams GR, Yen PM.

J Clin Endocrinol Metab. 2014 Mar;99(3):768-70. doi: 10.1210/jc.2013-3393. No abstract available.


Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism.

Refetoff S, Bassett JH, Beck-Peccoz P, Bernal J, Brent G, Chatterjee K, De Groot LJ, Dumitrescu AM, Jameson JL, Kopp PA, Murata Y, Persani L, Samarut J, Weiss RE, Williams GR, Yen PM.

Thyroid. 2014 Mar;24(3):407-9. doi: 10.1089/thy.2013.3393.nomen. Epub 2014 Mar 4. No abstract available.


Introduction of John T. Potts Jr.

Jameson JL.

J Clin Invest. 2013 Nov;123(11):4971-7. doi: 10.1172/JCI73227. Epub 2013 Nov 1. No abstract available.


Serum from methimazole-treated patients induces activation of aryl hydrocarbon receptor, a transcription factor that binds to dioxin-response elements.

Ishikawa T, Okinaga H, Takahashi S, Numakura M, Mashimo Y, Yoshimura N, Maeda T, Inoue D, Okazaki R, Kinoshita M, Jameson JL, Teramoto T.

Thyroid. 2012 Aug;22(8):769-77. doi: 10.1089/thy.2012.0057. Epub 2012 Jul 11.


Minimizing unnecessary surgery for thyroid nodules.

Jameson JL.

N Engl J Med. 2012 Aug 23;367(8):765-7. doi: 10.1056/NEJMe1205893. Epub 2012 Jun 25. No abstract available.


ENU mutagenesis in mice identifies candidate genes for hypogonadism.

Weiss J, Hurley LA, Harris RM, Finlayson C, Tong M, Fisher LA, Moran JL, Beier DR, Mason C, Jameson JL.

Mamm Genome. 2012 Jun;23(5-6):346-55. doi: 10.1007/s00335-011-9388-5. Epub 2012 Jan 19.


Male hypogonadism and germ cell loss caused by a mutation in Polo-like kinase 4.

Harris RM, Weiss J, Jameson JL.

Endocrinology. 2011 Oct;152(10):3975-85. doi: 10.1210/en.2011-1106. Epub 2011 Jul 26.


Hypogonadotropic hypogonadism in subjects with DAX1 mutations.

Jadhav U, Harris RM, Jameson JL.

Mol Cell Endocrinol. 2011 Oct 22;346(1-2):65-73. doi: 10.1016/j.mce.2011.04.017. Epub 2011 Jun 13. Review.


Steroidogenic factor-1 (SF-1)-driven differentiation of murine embryonic stem (ES) cells into a gonadal lineage.

Jadhav U, Jameson JL.

Endocrinology. 2011 Jul;152(7):2870-82. doi: 10.1210/en.2011-0219. Epub 2011 May 24.


Sox3 functions in a cell-autonomous manner to regulate spermatogonial differentiation in mice.

Laronda MM, Jameson JL.

Endocrinology. 2011 Apr;152(4):1606-15. doi: 10.1210/en.2010-1249. Epub 2011 Jan 19.


Genetic rescue of nonclassical ERα signaling normalizes energy balance in obese Erα-null mutant mice.

Park CJ, Zhao Z, Glidewell-Kenney C, Lazic M, Chambon P, Krust A, Weiss J, Clegg DJ, Dunaif A, Jameson JL, Levine JE.

J Clin Invest. 2011 Feb;121(2):604-12. doi: 10.1172/JCI41702. Epub 2011 Jan 18.


A missense mutation in LRR8 of RXFP2 is associated with cryptorchidism.

Harris RM, Finlayson C, Weiss J, Fisher L, Hurley L, Barrett T, Emge D, Bathgate RA, Agoulnik AI, Jameson JL.

Mamm Genome. 2010 Oct;21(9-10):442-9. doi: 10.1007/s00335-010-9291-5. Epub 2010 Oct 22.


The effect of relaxin on cell proliferation in mouse cervix requires estrogen receptor {alpha} binding to estrogen response elements in stromal cells.

Yao L, Cooke PS, Meling DD, Shanks RD, Jameson JL, Sherwood OD.

Endocrinology. 2010 Jun;151(6):2811-8. doi: 10.1210/en.2009-1327. Epub 2010 Mar 22.


Selective disruption of ER{alpha} DNA-binding activity alters uterine responsiveness to estradiol.

Hewitt SC, O'Brien JE, Jameson JL, Kissling GE, Korach KS.

Mol Endocrinol. 2009 Dec;23(12):2111-6. doi: 10.1210/me.2009-0356. Epub 2009 Oct 7.


Foxl2, a forkhead transcription factor, modulates nonclassical activity of the estrogen receptor-alpha.

Kim SY, Weiss J, Tong M, Laronda MM, Lee EJ, Jameson JL.

Endocrinology. 2009 Nov;150(11):5085-93. doi: 10.1210/en.2009-0313. Epub 2009 Sep 24.


Regulation of Kiss1 and dynorphin gene expression in the murine brain by classical and nonclassical estrogen receptor pathways.

Gottsch ML, Navarro VM, Zhao Z, Glidewell-Kenney C, Weiss J, Jameson JL, Clifton DK, Levine JE, Steiner RA.

J Neurosci. 2009 Jul 22;29(29):9390-5. doi: 10.1523/JNEUROSCI.0763-09.2009.


Aromatase promoter I.f is regulated by estrogen receptor alpha (ESR1) in mouse hypothalamic neuronal cell lines.

Yilmaz MB, Wolfe A, Cheng YH, Glidewell-Kenney C, Jameson JL, Bulun SE.

Biol Reprod. 2009 Nov;81(5):956-65. doi: 10.1095/biolreprod.109.077206. Epub 2009 Jul 15.


Absence of activating mutations of CXCR4 in pituitary tumours.

Lee YH, Noh TW, Lee MK, Jameson JL, Lee EJ.

Clin Endocrinol (Oxf). 2010 Feb;72(2):209-13. doi: 10.1111/j.1365-2265.2009.03629.x. Epub 2009 May 16.


p21-Activated kinase mediates rapid estradiol-negative feedback actions in the reproductive axis.

Zhao Z, Park C, McDevitt MA, Glidewell-Kenney C, Chambon P, Weiss J, Jameson JL, Levine JE.

Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):7221-6. doi: 10.1073/pnas.0812597106. Epub 2009 Apr 9.


Estrogen actions in the male reproductive system involve estrogen response element-independent pathways.

Weiss J, Bernhardt ML, Laronda MM, Hurley LA, Glidewell-Kenney C, Pillai S, Tong M, Korach KS, Jameson JL.

Endocrinology. 2008 Dec;149(12):6198-206. doi: 10.1210/en.2008-0122. Epub 2008 Aug 21.


Splice variants of the forkhead box protein AFX exhibit dominant negative activity and inhibit AFXalpha-mediated tumor cell apoptosis.

Lee EJ, Kim JM, Lee MK, Jameson JL.

PLoS One. 2008 Jul 23;3(7):e2743. doi: 10.1371/journal.pone.0002743.


Classical estrogen receptor alpha signaling mediates negative and positive feedback on gonadotropin-releasing hormone neuron firing.

Christian CA, Glidewell-Kenney C, Jameson JL, Moenter SM.

Endocrinology. 2008 Nov;149(11):5328-34. doi: 10.1210/en.2008-0520. Epub 2008 Jul 17.


A phenotypic spectrum of sexual development in Dax1 (Nr0b1)-deficient mice: consequence of the C57BL/6J strain on sex determination.

Park SY, Lee EJ, Emge D, Jahn CL, Jameson JL.

Biol Reprod. 2008 Dec;79(6):1038-45. doi: 10.1095/biolreprod.108.069492. Epub 2008 Jul 16.


New insights into the classical and non-classical actions of estrogen: evidence from estrogen receptor knock-out and knock-in mice.

McDevitt MA, Glidewell-Kenney C, Jimenez MA, Ahearn PC, Weiss J, Jameson JL, Levine JE.

Mol Cell Endocrinol. 2008 Aug 13;290(1-2):24-30. doi: 10.1016/j.mce.2008.04.003. Epub 2008 Apr 20. Review.


Estrogen receptor alpha signaling pathways differentially regulate gonadotropin subunit gene expression and serum follicle-stimulating hormone in the female mouse.

Glidewell-Kenney C, Weiss J, Hurley LA, Levine JE, Jameson JL.

Endocrinology. 2008 Aug;149(8):4168-76. doi: 10.1210/en.2007-1807. Epub 2008 May 8.


HoxD10 gene delivery using adenovirus/adeno-associate hybrid virus inhibits the proliferation and tumorigenicity of GH4 pituitary lactotrope tumor cells.

Cho MA, Yashar P, Kim SK, Noh T, Gillam MP, Lee EJ, Jameson JL.

Biochem Biophys Res Commun. 2008 Jul 4;371(3):371-4. doi: 10.1016/j.bbrc.2008.04.085. Epub 2008 Apr 28.


The Role of DAX-1 in Reproduction.

Yu RN, Achermann JC, Ito M, Jameson JL.

Trends Endocrinol Metab. 1998 Jul;9(5):169-75.


Rites of passage through puberty: a complex genetic ensemble.

Jameson JL.

Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17247-8. Epub 2007 Oct 24. No abstract available.


Estrogen response element-independent estrogen receptor (ER)-alpha signaling does not rescue sexual behavior but restores normal testosterone secretion in male ERalpha knockout mice.

McDevitt MA, Glidewell-Kenney C, Weiss J, Chambon P, Jameson JL, Levine JE.

Endocrinology. 2007 Nov;148(11):5288-94. Epub 2007 Aug 2.


Distinct roles for steroidogenic factor 1 and desert hedgehog pathways in fetal and adult Leydig cell development.

Park SY, Tong M, Jameson JL.

Endocrinology. 2007 Aug;148(8):3704-10. Epub 2007 May 10.


Nonclassical estrogen receptor alpha signaling mediates negative feedback in the female mouse reproductive axis.

Glidewell-Kenney C, Hurley LA, Pfaff L, Weiss J, Levine JE, Jameson JL.

Proc Natl Acad Sci U S A. 2007 May 8;104(19):8173-7. Epub 2007 Apr 30.


Islet cell differentiation in liver by combinatorial expression of transcription factors neurogenin-3, BETA2, and RIPE3b1.

Song YD, Lee EJ, Yashar P, Pfaff LE, Kim SY, Jameson JL.

Biochem Biophys Res Commun. 2007 Mar 9;354(2):334-9. Epub 2007 Jan 10.


Effects of loss of classical estrogen response element signaling on bone in male mice.

Syed FA, Fraser DG, Spelsberg TC, Rosen CJ, Krust A, Chambon P, Jameson JL, Khosla S.

Endocrinology. 2007 Apr;148(4):1902-10. Epub 2007 Jan 4.


Heterozygous missense mutations in steroidogenic factor 1 (SF1/Ad4BP, NR5A1) are associated with 46,XY disorders of sex development with normal adrenal function.

Lin L, Philibert P, Ferraz-de-Souza B, Kelberman D, Homfray T, Albanese A, Molini V, Sebire NJ, Einaudi S, Conway GS, Hughes IA, Jameson JL, Sultan C, Dattani MT, Achermann JC.

J Clin Endocrinol Metab. 2007 Mar;92(3):991-9. Epub 2007 Jan 2.


An amino-terminal DAX1 (NROB1) missense mutation associated with isolated mineralocorticoid deficiency.

Verrijn Stuart AA, Ozisik G, de Vroede MA, Giltay JC, Sinke RJ, Peterson TJ, Harris RM, Weiss J, Jameson JL.

J Clin Endocrinol Metab. 2007 Mar;92(3):755-61. Epub 2006 Dec 12.


Gene transfer of pigment epithelium-derived factor suppresses tumor growth and angiogenesis in a hepatoblastoma xenograft model.

Browne M, Stellmach V, Cornwell M, Chung C, Doll JA, Lee EJ, Jameson JL, Reynolds M, Superina RA, Abramson LP, Crawford SE.

Pediatr Res. 2006 Sep;60(3):282-7. Epub 2006 Jul 20.


Estrogen-induced proliferation of uterine epithelial cells is independent of estrogen receptor alpha binding to classical estrogen response elements.

O'Brien JE, Peterson TJ, Tong MH, Lee EJ, Pfaff LE, Hewitt SC, Korach KS, Weiss J, Jameson JL.

J Biol Chem. 2006 Sep 8;281(36):26683-92. Epub 2006 Jul 17.


Two sisters with IMAGe syndrome: cytomegalic adrenal histopathology, support for autosomal recessive inheritance and literature review.

Tan TY, Jameson JL, Campbell PE, Ekert PG, Zacharin M, Savarirayan R.

Am J Med Genet A. 2006 Aug 15;140(16):1778-84.


Analysis of DAX1 (NR0B1) and steroidogenic factor-1 (NR5A1) in children and adults with primary adrenal failure: ten years' experience.

Lin L, Gu WX, Ozisik G, To WS, Owen CJ, Jameson JL, Achermann JC.

J Clin Endocrinol Metab. 2006 Aug;91(8):3048-54. Epub 2006 May 9.

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