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Items: 14


Effect of Phosphorylation on Interactions between Transmembrane Domains of SERCA and Phospholamban.

Martin PD, James ZM, Thomas DD.

Biophys J. 2018 Jun 5;114(11):2573-2583. doi: 10.1016/j.bpj.2018.04.035.


Dynamic rearrangement of the intrinsic ligand regulates KCNH potassium channels.

Dai G, James ZM, Zagotta WN.

J Gen Physiol. 2018 Apr 2;150(4):625-635. doi: 10.1085/jgp.201711989. Epub 2018 Mar 22.


Structural insights into the mechanisms of CNBD channel function.

James ZM, Zagotta WN.

J Gen Physiol. 2018 Feb 5;150(2):225-244. doi: 10.1085/jgp.201711898. Epub 2017 Dec 12. Review.


The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human αVβ3 Integrin via Steric Hindrance.

Borst AJ, James ZM, Zagotta WN, Ginsberg M, Rey FA, DiMaio F, Backovic M, Veesler D.

Structure. 2017 Nov 7;25(11):1732-1739.e5. doi: 10.1016/j.str.2017.09.007. Epub 2017 Oct 12.


CryoEM structure of a prokaryotic cyclic nucleotide-gated ion channel.

James ZM, Borst AJ, Haitin Y, Frenz B, DiMaio F, Zagotta WN, Veesler D.

Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):4430-4435. doi: 10.1073/pnas.1700248114. Epub 2017 Apr 10.


A bifunctional spin label reports the structural topology of phospholamban in magnetically-aligned bicelles.

McCaffrey JE, James ZM, Svensson B, Binder BP, Thomas DD.

J Magn Reson. 2016 Jan;262:50-56. doi: 10.1016/j.jmr.2015.12.005. Epub 2015 Dec 12.


Erratum: Structural Mechanism for Regulation of Bcl-2 protein Noxa by phosphorylation.

Karim CB, Michel Espinoza-Fonseca L, James ZM, Hanse EA, Gaynes JS, Thomas DD, Kelekar A.

Sci Rep. 2015 Oct 29;5:15872. doi: 10.1038/srep15872. No abstract available.


Structural Mechanism for Regulation of Bcl-2 protein Noxa by phosphorylation.

Karim CB, Espinoza-Fonseca LM, James ZM, Hanse EA, Gaynes JS, Thomas DD, Kelekar A.

Sci Rep. 2015 Sep 28;5:14557. doi: 10.1038/srep14557. Erratum in: Sci Rep. 2015;5:15872.


Optimization of bicelle lipid composition and temperature for EPR spectroscopy of aligned membranes.

McCaffrey JE, James ZM, Thomas DD.

J Magn Reson. 2015 Jan;250:71-75. doi: 10.1016/j.jmr.2014.09.026. Epub 2014 Oct 13.


Synthetic phosphopeptides enable quantitation of the content and function of the four phosphorylation states of phospholamban in cardiac muscle.

Ablorh NA, Dong X, James ZM, Xiong Q, Zhang J, Thomas DD, Karim CB.

J Biol Chem. 2014 Oct 17;289(42):29397-405. doi: 10.1074/jbc.M114.556621. Epub 2014 Sep 4.


Open and closed conformations of the isolated transmembrane domain of death receptor 5 support a new model of activation.

Lewis AK, James ZM, McCaffrey JE, Braun AR, Karim CB, Thomas DD, Sachs JN.

Biophys J. 2014 Mar 18;106(6):L21-4. doi: 10.1016/j.bpj.2014.01.044.


Protein-protein interactions in calcium transport regulation probed by saturation transfer electron paramagnetic resonance.

James ZM, McCaffrey JE, Torgersen KD, Karim CB, Thomas DD.

Biophys J. 2012 Sep 19;103(6):1370-8. doi: 10.1016/j.bpj.2012.08.032.


Structural and functional dynamics of an integral membrane protein complex modulated by lipid headgroup charge.

Li J, James ZM, Dong X, Karim CB, Thomas DD.

J Mol Biol. 2012 May 18;418(5):379-89. doi: 10.1016/j.jmb.2012.02.011. Epub 2012 Feb 28.


Large-scale opening of utrophin's tandem calponin homology (CH) domains upon actin binding by an induced-fit mechanism.

Lin AY, Prochniewicz E, James ZM, Svensson B, Thomas DD.

Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12729-33. doi: 10.1073/pnas.1106453108. Epub 2011 Jul 18.

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