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A phase II trial of recombinant MAGE-A3 protein with immunostimulant AS15 in combination with high-dose Interleukin-2 (HDIL2) induction therapy in metastatic melanoma.

McQuade JL, Homsi J, Torres-Cabala CA, Bassett R, Popuri RM, James ML, Vence LM, Hwu WJ.

BMC Cancer. 2018 Dec 19;18(1):1274. doi: 10.1186/s12885-018-5193-9.


External Validation of Hematoma Expansion Scores in Spontaneous Intracerebral Hemorrhage in an Asian Patient Cohort.

Lim JX, Han JX, See AAQ, Lew VH, Chock WT, Ban VF, Pothiawala S, Lim WEH, McAdory LE, James ML, King NKK.

Neurocrit Care. 2018 Oct 30. doi: 10.1007/s12028-018-0631-8. [Epub ahead of print]


Cardioembolic Stroke Risk and Recovery After Anticoagulation-Related Intracerebral Hemorrhage.

Murphy MP, Kuramatsu JB, Leasure A, Falcone GJ, Kamel H, Sansing LH, Kourkoulis C, Schwab K, Elm JJ, Gurol ME, Tran H, Greenberg SM, Viswanathan A, Anderson CD, Schwab S, Rosand J, Shi FD, Kittner SJ, Testai FD, Woo D, Langefeld CD, James ML, Koch S, Huttner HB, Biffi A, Sheth KN.

Stroke. 2018 Nov;49(11):2652-2658. doi: 10.1161/STROKEAHA.118.021799.


Successful treatment of chronic knee pain following localization by a sigma-1 receptor radioligand and PET/MRI: a case report.

Cipriano PW, Lee SW, Yoon D, Shen B, Tawfik VL, Curtin CM, Dragoo JL, James ML, McCurdy CR, Chin FT, Biswal S.

J Pain Res. 2018 Oct 12;11:2353-2357. doi: 10.2147/JPR.S167839. eCollection 2018.


Longitudinal Changes in Regional Cerebral Perfusion and Cognition After Cardiac Operation.

Smith PJ, Browndyke JN, Monge ZA, Harshbarger TB, James ML, Gaca JG, Alexander JH, Berger MM, Newman MF, Milano CA, Mathew JP; Neurologic Outcomes Research Group (NORG).

Ann Thorac Surg. 2019 Jan;107(1):112-118. doi: 10.1016/j.athoracsur.2018.07.056. Epub 2018 Sep 22.


Long-term recovery profile of patients with severe disability or in vegetative states following severe primary intracerebral hemorrhage.

Lee L, Lo YT, See AAQ, Hsieh PJ, James ML, King NKK.

J Crit Care. 2018 Dec;48:269-275. doi: 10.1016/j.jcrc.2018.09.010. Epub 2018 Sep 15.


Comparison of Genetic and Self-Identified Ancestry in Modeling Intracerebral Hemorrhage Risk.

Marini S, Lena UK, Crawford KM, Moomaw CJ, Testai FD, Kittner SJ, James ML, Woo D, Langefeld CD, Rosand J, Anderson CD.

Front Neurol. 2018 Jul 6;9:514. doi: 10.3389/fneur.2018.00514. eCollection 2018.


Venous Thromboembolism in Patients With Spontaneous Intracerebral Hemorrhage: A Multicenter Study.

Ding D, Sekar P, Moomaw CJ, Comeau ME, James ML, Testai F, Flaherty ML, Vashkevich A, Worrall BB, Woo D, Osborne J.

Neurosurgery. 2018 Jul 13. doi: 10.1093/neuros/nyy333. [Epub ahead of print]


PET Imaging of Neuroinflammation Using [11C]DPA-713 in a Mouse Model of Ischemic Stroke.

Chaney AM, Johnson EM, Cropper HC, James ML.

J Vis Exp. 2018 Jun 14;(136). doi: 10.3791/57243.


11C-DPA-713 Versus 18F-GE-180: A Preclinical Comparison of Translocator Protein 18 kDa PET Tracers to Visualize Acute and Chronic Neuroinflammation in a Mouse Model of Ischemic Stroke.

Chaney A, Cropper HC, Johnson EM, Lechtenberg KJ, Peterson TC, Stevens MY, Buckwalter MS, James ML.

J Nucl Med. 2019 Jan;60(1):122-128. doi: 10.2967/jnumed.118.209155. Epub 2018 Jul 5.


Minority Patients are Less Likely to Undergo Withdrawal of Care After Spontaneous Intracerebral Hemorrhage.

Ormseth CH, Falcone GJ, Jasak SD, Mampre DM, Leasure AC, Miyares LC, Hwang DY, James ML, Testai FD, Becker KJ, Tirschwell DL, Langefeld CD, Woo D, Sheth KN.

Neurocrit Care. 2018 Dec;29(3):419-425. doi: 10.1007/s12028-018-0554-4.


Hypertension and intracerebral hemorrhage recurrence among white, black, and Hispanic individuals.

Rodriguez-Torres A, Murphy M, Kourkoulis C, Schwab K, Ayres AM, Moomaw CJ, Young Kwon S, Berthaud JV, Gurol ME, Greenberg SM, Viswanathan A, Anderson CD, Flaherty M, James ML, Birnbaum L, Yong Sung G, Parikh G, Boehme AK, Mayson D, Sheth KN, Kidwell C, Koch S, Frankel M, Langefeld CD, Testai FD, Woo D, Rosand J, Biffi A.

Neurology. 2018 Jul 3;91(1):e37-e44. doi: 10.1212/WNL.0000000000005729. Epub 2018 Jun 6.


TSPO-PET imaging using [18F]PBR06 is a potential translatable biomarker for treatment response in Huntington's disease: preclinical evidence with the p75NTR ligand LM11A-31.

Simmons DA, James ML, Belichenko NP, Semaan S, Condon C, Kuan J, Shuhendler AJ, Miao Z, Chin FT, Longo FM.

Hum Mol Genet. 2018 Aug 15;27(16):2893-2912. doi: 10.1093/hmg/ddy202.


Sex Differences in Gene and Protein Expression After Intracerebral Hemorrhage in Mice.

Xie Y, Li YJ, Lei B, Kernagis D, Liu WW, Bennett ER, Venkatraman T, Lascola CD, Laskowitz DT, Warner DS, James ML.

Transl Stroke Res. 2018 May 13. doi: 10.1007/s12975-018-0633-z. [Epub ahead of print]


Survival and independence after intracerebral hemorrhage: Trends and opportunities.

Anderson CD, James ML.

Neurology. 2018 Jun 5;90(23):1043-1044. doi: 10.1212/WNL.0000000000005625. Epub 2018 May 4. No abstract available.


Associations between Patient Characteristics and a New, Early Do-Not-Attempt Resuscitation Order after Intracerebral Hemorrhage.

McFarlin J, Hailey CE, Qi W, Kranz PG, Sun W, Sun W, Gray M, King NKK, Laskowitz DT, James ML.

J Palliat Med. 2018 Aug;21(8):1161-1165. doi: 10.1089/jpm.2017.0519. Epub 2018 Apr 20.


Imaging activated T cells predicts response to cancer vaccines.

Alam IS, Mayer AT, Sagiv-Barfi I, Wang K, Vermesh O, Czerwinski DK, Johnson EM, James ML, Levy R, Gambhir SS.

J Clin Invest. 2018 Jun 1;128(6):2569-2580. doi: 10.1172/JCI98509. Epub 2018 May 14.


Spinal cord injury pharmacotherapy: Current research & development and competitive commercial landscape as of 2015.

Guercio JR, Kralic JE, Marrotte EJ, James ML.

J Spinal Cord Med. 2019 Jan;42(1):102-122. doi: 10.1080/10790268.2018.1439803. Epub 2018 Feb 27.


[18F]FSPG-PET reveals increased cystine/glutamate antiporter (xc-) activity in a mouse model of multiple sclerosis.

Hoehne A, James ML, Alam IS, Ronald JA, Schneider B, D'Souza A, Witney TH, Andrews LE, Cropper HC, Behera D, Gowrishankar G, Ding Z, Wyss-Coray T, Chin FT, Biswal S, Gambhir SS.

J Neuroinflammation. 2018 Feb 22;15(1):55. doi: 10.1186/s12974-018-1080-1.


Spontaneous Intracerebral Hemorrhage: Should We Operate?

Babi MA, James ML.

Front Neurol. 2017 Dec 4;8:645. doi: 10.3389/fneur.2017.00645. eCollection 2017. No abstract available.


Systemic inflammatory response syndrome, infection, and outcome in intracerebral hemorrhage.

Boehme AK, Comeau ME, Langefeld CD, Lord A, Moomaw CJ, Osborne J, James ML, Martini S, Testai FD, Woo D, Elkind MSV.

Neurol Neuroimmunol Neuroinflamm. 2017 Dec 22;5(2):e428. doi: 10.1212/NXI.0000000000000428. eCollection 2018 Mar.


The Effect of Propofol vs. Isoflurane Anesthesia on Postoperative Changes in Cerebrospinal Fluid Cytokine Levels: Results from a Randomized Trial.

Berger M, Ponnusamy V, Greene N, Cooter M, Nadler JW, Friedman A, McDonagh DL, Laskowitz DT, Newman MF, Shaw LM, Warner DS, Mathew JP, James ML; MAD-PIA Investigators.

Front Immunol. 2017 Nov 13;8:1528. doi: 10.3389/fimmu.2017.01528. eCollection 2017.


The State of Neurocritical Care Fellowship Training and Attitudes toward Accreditation and Certification: A Survey of Neurocritical Care Fellowship Program Directors.

Dhar R, Rajajee V, Finley Caulfield A, Maas MB, James ML, Kumar AB, Figueroa SA, McDonagh D, Ardelt A.

Front Neurol. 2017 Nov 3;8:548. doi: 10.3389/fneur.2017.00548. eCollection 2017.


Author response: Ischemic Lesions, blood pressure dysregulation, and poor outcomes in intracerebral hemorrhage.

Kidwell CS, Rosand J, Norato G, Dixon S, Worrall BB, James ML, Elkind MSV, Flaherty ML, Osborne J, Vashkevich A, Langefeld CD, Moomaw CJ, Woo D.

Neurology. 2017 Oct 17;89(16):1755-1756. doi: 10.1212/WNL.0000000000004509. No abstract available.


Hearing the Voice of the Resident in Long-Term Care Facilities-An Internationally Based Approach to Assessing Quality of Life.

Morris JN, Declercq A, Hirdes JP, Finne-Soveri H, Fries BE, James ML, Geffen L, Kehyayan V, Saks K, Szczerbińska K, Topinkova E.

J Am Med Dir Assoc. 2018 Mar;19(3):207-215. doi: 10.1016/j.jamda.2017.08.010. Epub 2017 Oct 10.


Association of IL6ST (gp130) Polymorphism with Functional Outcome Following Spontaneous Intracerebral Hemorrhage.

El Husseini N, Hoffman BM, Bennett ER, Li YW, Williamson Taylor RA, Hailey CE, Richardson K, Li YJ, Laskowitz DT, James ML.

J Stroke Cerebrovasc Dis. 2018 Jan;27(1):125-131. doi: 10.1016/j.jstrokecerebrovasdis.2017.08.017. Epub 2017 Sep 28.


Visualizing Nerve Injury in a Neuropathic Pain Model with [18F]FTC-146 PET/MRI.

Shen B, Behera D, James ML, Reyes ST, Andrews L, Cipriano PW, Klukinov M, Lutz AB, Mavlyutov T, Rosenberg J, Ruoho AE, McCurdy CR, Gambhir SS, Yeomans DC, Biswal S, Chin FT.

Theranostics. 2017 Jul 8;7(11):2794-2805. doi: 10.7150/thno.19378. eCollection 2017.


Factors Considered by Clinicians when Prognosticating Intracerebral Hemorrhage Outcomes.

Hwang DY, Chu SY, Dell CA, Sparks MJ, Watson TD, Langefeld CD, Comeau ME, Rosand J, Battey TWK, Koch S, Perez ML, James ML, McFarlin J, Osborne JL, Woo D, Kittner SJ, Sheth KN.

Neurocrit Care. 2017 Dec;27(3):316-325. doi: 10.1007/s12028-017-0430-7.


Assessment of the interaction of age and sex on 90-day outcome after intracerebral hemorrhage.

James ML, Langefeld CD, Sekar P, Moomaw CJ, Elkind MSV, Worrall BB, Sheth KN, Martini SR, Osborne J, Woo D; ERICH Investigators.

Neurology. 2017 Sep 5;89(10):1011-1019. doi: 10.1212/WNL.0000000000004255. Epub 2017 Jul 14.


Imaging B Cells in a Mouse Model of Multiple Sclerosis Using 64Cu-Rituximab PET.

James ML, Hoehne A, Mayer AT, Lechtenberg K, Moreno M, Gowrishankar G, Ilovich O, Natarajan A, Johnson EM, Nguyen J, Quach L, Han M, Buckwalter M, Chandra S, Gambhir SS.

J Nucl Med. 2017 Nov;58(11):1845-1851. doi: 10.2967/jnumed.117.189597. Epub 2017 Jul 7.


Aggressiveness of care following intracerebral hemorrhage in women and men.

Guha R, Boehme A, Demel SL, Li JJ, Cai X, James ML, Koch S, Langefeld CD, Moomaw CJ, Osborne J, Sekar P, Sheth KN, Woodrich E, Worrall BB, Woo D, Chaturvedi S.

Neurology. 2017 Jul 25;89(4):349-354. doi: 10.1212/WNL.0000000000004143. Epub 2017 Jun 28.


Bovine antibodies targeting primary and recurrent Clostridium difficile disease are a potent antibiotic alternative.

Hutton ML, Cunningham BA, Mackin KE, Lyon SA, James ML, Rood JI, Lyras D.

Sci Rep. 2017 Jun 16;7(1):3665. doi: 10.1038/s41598-017-03982-5.


Female gonadal hormone effects on microglial activation and functional outcomes in a mouse model of moderate traumatic brain injury.

Umeano O, Wang H, Dawson H, Lei B, Umeano A, Kernagis D, James ML.

World J Crit Care Med. 2017 May 4;6(2):107-115. doi: 10.5492/wjccm.v6.i2.107. eCollection 2017 May 4.


[18F]GE-180 PET Detects Reduced Microglia Activation After LM11A-31 Therapy in a Mouse Model of Alzheimer's Disease.

James ML, Belichenko NP, Shuhendler AJ, Hoehne A, Andrews LE, Condon C, Nguyen TV, Reiser V, Jones P, Trigg W, Rao J, Gambhir SS, Longo FM.

Theranostics. 2017 Mar 24;7(6):1422-1436. doi: 10.7150/thno.17666. eCollection 2017.


Multimodal assessment of SERS nanoparticle biodistribution post ingestion reveals new potential for clinical translation of Raman imaging.

Campbell JL, SoRelle ED, Ilovich O, Liba O, James ML, Qiu Z, Perez V, Chan CT, de la Zerda A, Zavaleta C.

Biomaterials. 2017 Aug;135:42-52. doi: 10.1016/j.biomaterials.2017.04.045. Epub 2017 Apr 28.


Human umbilical cord plasma proteins revitalize hippocampal function in aged mice.

Castellano JM, Mosher KI, Abbey RJ, McBride AA, James ML, Berdnik D, Shen JC, Zou B, Xie XS, Tingle M, Hinkson IV, Angst MS, Wyss-Coray T.

Nature. 2017 Apr 27;544(7651):488-492. doi: 10.1038/nature22067. Epub 2017 Apr 19.


Development of [18F]DASA-23 for Imaging Tumor Glycolysis Through Noninvasive Measurement of Pyruvate Kinase M2.

Beinat C, Alam IS, James ML, Srinivasan A, Gambhir SS.

Mol Imaging Biol. 2017 Oct;19(5):665-672. doi: 10.1007/s11307-017-1068-8.


Peri-Hemorrhagic Edema and Secondary Hematoma Expansion after Intracerebral Hemorrhage: From Benchwork to Practical Aspects.

Babi MA, James ML.

Front Neurol. 2017 Jan 19;8:4. doi: 10.3389/fneur.2017.00004. eCollection 2017. Review.


Ischemic lesions, blood pressure dysregulation, and poor outcomes in intracerebral hemorrhage.

Kidwell CS, Rosand J, Norato G, Dixon S, Worrall BB, James ML, Elkind MS, Flaherty ML, Osborne J, Vashkevich A, Langefeld CD, Moomaw CJ, Woo D.

Neurology. 2017 Feb 21;88(8):782-788. doi: 10.1212/WNL.0000000000003630. Epub 2017 Jan 25.


Intervention quality is not routinely assessed in Cochrane systematic reviews of radiation therapy interventions.

Abdul Rahim MR, James ML, Hickey BE.

J Med Imaging Radiat Oncol. 2017 Oct;61(5):662-665. doi: 10.1111/1754-9485.12589. Epub 2017 Jan 19.


Analgesia and Sedation Requirements in Mechanically Ventilated Trauma Patients With Acute, Preinjury Use of Cocaine and/or Amphetamines.

Kram B, Kram SJ, Sharpe ML, James ML, Kuchibhatla M, Shapiro ML.

Anesth Analg. 2017 Mar;124(3):782-788. doi: 10.1213/ANE.0000000000001740.


Erratum: Neuroprotective pentapeptide CN-105 improves functional and histological outcomes in a murine model of intracerebral hemorrhage.

Lei B, James ML, Liu J, Zhou G, Venkatraman TN, Lascola CD, Acheson SK, Dubois LG, Laskowitz DT, Wang H.

Sci Rep. 2017 Jan 5;7:39580. doi: 10.1038/srep39580. No abstract available.


Evaluation of the Effect of Carbohydrate Intake on Postprandial Glucose in Patients With Type 1 Diabetes Treated With Insulin Pumps.

James ML, Green L, Amiel SA, Choudhary P.

J Diabetes Sci Technol. 2016 Nov 1;10(6):1287-1293. Print 2016 Nov.


Sex and Age Interactions and Differences in Outcomes After Intracerebral Hemorrhage.

James ML, Cox M, Xian Y, Smith EE, Bhatt DL, Schulte PJ, Hernandez A, Fonarow GC, Schwamm LH.

J Womens Health (Larchmt). 2017 Apr;26(4):380-388. doi: 10.1089/jwh.2016.5849. Epub 2016 Oct 18.


Neuroprotective pentapeptide CN-105 improves functional and histological outcomes in a murine model of intracerebral hemorrhage.

Lei B, James ML, Liu J, Zhou G, Venkatraman TN, Lascola CD, Acheson SK, Dubois LG, Laskowitz DT, Wang H.

Sci Rep. 2016 Oct 7;6:34834. doi: 10.1038/srep34834. Erratum in: Sci Rep. 2017 Jan 05;7:39580.


Neuromuscular Disease in the Neurointensive Care Unit.

Crespo V, James ML.

Anesthesiol Clin. 2016 Sep;34(3):601-19. doi: 10.1016/j.anclin.2016.04.010. Review.


Fraction size in radiation therapy for breast conservation in early breast cancer.

Hickey BE, James ML, Lehman M, Hider PN, Jeffery M, Francis DP, See AM.

Cochrane Database Syst Rev. 2016 Jul 18;7:CD003860. doi: 10.1002/14651858.CD003860.pub4. Review.


Sex differences exist after intracerebral hemorrhage but may not affect outcome.

Woo D, James ML.

Neurology. 2016 Jul 19;87(3):244. doi: 10.1212/WNL.0000000000002794. Epub 2016 Jun 8. No abstract available.


The Effect of Propofol Versus Isoflurane Anesthesia on Human Cerebrospinal Fluid Markers of Alzheimer's Disease: Results of a Randomized Trial.

Berger M, Nadler JW, Friedman A, McDonagh DL, Bennett ER, Cooter M, Qi W, Laskowitz DT, Ponnusamy V, Newman MF, Shaw LM, Warner DS, Mathew JP, James ML; MAD-PIA trial team.

J Alzheimers Dis. 2016 Apr 15;52(4):1299-310. doi: 10.3233/JAD-151190.


Hypofractionated radiation treatment in early breast cancer: Results in a New Zealand setting.

James ML, Dehn G, Robinson BA.

Asia Pac J Clin Oncol. 2016 Sep;12(3):248-53. doi: 10.1111/ajco.12458. Epub 2016 Mar 9.


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