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Blood Pressure Variability Predicts Poor In-Hospital Outcome in Spontaneous Intracerebral Hemorrhage.

Divani AA, Liu X, Di Napoli M, Lattanzi S, Ziai W, James ML, Jafarli A, Jafari M, Saver JL, Hemphill JC, Vespa PM, Mayer SA, Petersen A.

Stroke. 2019 Jun 20:STROKEAHA119025514. doi: 10.1161/STROKEAHA.119.025514. [Epub ahead of print]


Consensus workshops on the development of an ADHD medication management protocol using QbTest: developing a clinical trial protocol with multidisciplinary stakeholders.

Hall CL, Brown S, James M, Martin JL, Brown N, Selby K, Clarke J, Williams L, Sayal K, Hollis C, Groom MJ.

BMC Med Res Methodol. 2019 Jun 18;19(1):126. doi: 10.1186/s12874-019-0772-2.


Individualised screening for diabetic retinopathy: the ISDR study-rationale, design and methodology for a randomised controlled trial comparing annual and individualised risk-based variable-interval screening.

Broadbent DM, Sampson CJ, Wang A, Howard L, Williams AE, Howlin SU, Appelbe D, Moitt T, Cheyne CP, Rahni MM, Kelly J, Collins J, García-Fiñana M, Stratton IM, James M, Harding SP; ISDR Study Group.

BMJ Open. 2019 Jun 17;9(6):e025788. doi: 10.1136/bmjopen-2018-025788.


Natural history of limb girdle muscular dystrophy R9 over 6 years: searching for trial endpoints.

Murphy AP, Morrow J, Dahlqvist JR, Stojkovic T, Willis TA, Sinclair CDJ, Wastling S, Yousry T, Hanna MS, James MK, Mayhew A, Eagle M, Lee LE, Hogrel JY, Carlier PG, Thornton JS, Vissing J, Hollingsworth KG, Straub V.

Ann Clin Transl Neurol. 2019 May 16;6(6):1033-1045. doi: 10.1002/acn3.774. eCollection 2019 Jun.


Dichloroacetate-induced peripheral neuropathy.

Stacpoole PW, Martyniuk CJ, James MO, Calcutt NA.

Int Rev Neurobiol. 2019;145:211-238. doi: 10.1016/bs.irn.2019.05.003. Epub 2019 Jun 11.


Joint associations of obesity and estimated GFR with clinical outcomes: a population-based cohort study.

Tonelli M, Wiebe N, Kovesdy CP, James MT, Klarenbach SW, Manns BJ, Hemmelgarn BR; Alberta Kidney Disease Network.

BMC Nephrol. 2019 Jun 6;20(1):204. doi: 10.1186/s12882-019-1351-9.


Maximising access to thrombectomy services for stroke in England: A modelling study.

Allen M, Pearn K, James M, Ford GA, White P, Rudd AG, McMeekin P, Stein K.

Eur Stroke J. 2019 Mar;4(1):39-49. doi: 10.1177/2396987318785421. Epub 2018 Jul 19.


Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial.

Al-Shahi Salman R, Minks DP, Mitra D, Rodrigues MA, Bhatnagar P, du Plessis JC, Joshi Y, Dennis MS, Murray GD, Newby DE, Sandercock PAG, Sprigg N, Stephen J, Sudlow CLM, Werring DJ, Whiteley WN, Wardlaw JM, White PM; RESTART Collaboration.

Lancet Neurol. 2019 Jul;18(7):643-652. doi: 10.1016/S1474-4422(19)30184-X. Epub 2019 May 22.


Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial.

RESTART Collaboration.

Lancet. 2019 May 21. pii: S0140-6736(19)30840-2. doi: 10.1016/S0140-6736(19)30840-2. [Epub ahead of print]


Towards regulatory endorsement of drug development tools to promote the application of model-informed drug development in Duchenne muscular dystrophy.

Conrado DJ, Larkindale J, Berg A, Hill M, Burton J, Abrams KR, Abresch RT, Bronson A, Chapman D, Crowther M, Duong T, Gordish-Dressman H, Harnisch L, Henricson E, Kim S, McDonald CM, Schmidt S, Vong C, Wang X, Wong BL, Yong F, Romero K; Duchenne Muscular Dystrophy Regulatory Science Consortium (D-RSC).

J Pharmacokinet Pharmacodyn. 2019 May 24. doi: 10.1007/s10928-019-09642-7. [Epub ahead of print]


Reverse engineering field-derived vertical distribution profiles to infer larval swimming behaviors.

James MK, Polton JA, Brereton AR, Howell KL, Nimmo-Smith WAM, Knights AM.

Proc Natl Acad Sci U S A. 2019 Jun 11;116(24):11818-11823. doi: 10.1073/pnas.1900238116. Epub 2019 May 23.


The role of orexin-1 receptor signaling in demand for the opioid fentanyl.

Fragale JE, Pantazis CB, James MH, Aston-Jones G.

Neuropsychopharmacology. 2019 May 21. doi: 10.1038/s41386-019-0420-x. [Epub ahead of print]


Malaria impact on cognitive function of children in a peri-urban community in the Brazilian Amazon.

Tapajós R, Castro D, Melo G, Balogun S, James M, Pessoa R, Almeida A, Costa M, Pinto R, Albuquerque B, Monteiro W, Braga J, Lacerda M, Mourão MP.

Malar J. 2019 May 16;18(1):173. doi: 10.1186/s12936-019-2802-2.


Longitudinal TSPO-PET imaging of peripheral and central myeloid cells in a mouse model of complex regional pain syndrome.

Cropper HC, Johnson EM, Haight E, Cordonnier SA, Chaney AM, Forman TE, Biswal A, Stevens MY, James ML, Tawfik VL.

Pain. 2019 May 8. doi: 10.1097/j.pain.0000000000001607. [Epub ahead of print]


The Integrative Physiology of Exercise Training in Patients with COPD.

Neder JA, Marillier M, Bernard AC, James MD, Milne KM, O'Donnell DE.

COPD. 2019 May 16:1-14. doi: 10.1080/15412555.2019.1606189. [Epub ahead of print]


What works best when implementing a physical activity intervention for teenagers? Reflections from the ACTIVE Project: a qualitative study.

James M, Christian D, Scott S, Todd C, Stratton G, Demmler J, McCoubrey S, Halcox J, Audrey S, Ellins EA, Irvine E, Brophy S.

BMJ Open. 2019 May 10;9(5):e025618. doi: 10.1136/bmjopen-2018-025618.


The Pathophysiology of Dyspnea and Exercise Intolerance in Chronic Obstructive Pulmonary Disease.

O'Donnell DE, James MD, Milne KM, Neder JA.

Clin Chest Med. 2019 Jun;40(2):343-366. doi: 10.1016/j.ccm.2019.02.007. Review.


Long-Term Outcomes of Brachial Plexus Reconstruction with Sural Nerve Autograft for Brachial Plexus Birth Injury.

Manske MC, Bauer AS, Hentz VR, James MA.

Plast Reconstr Surg. 2019 May;143(5):1017e-1026e. doi: 10.1097/PRS.0000000000005557.


The orexin-1 receptor antagonist SB-334867 reduces motivation, but not inhibitory control, in a rat stop signal task.

Wiskerke J, James MH, Aston-Jones G.

Brain Res. 2019 Apr 16. pii: S0006-8993(19)30216-1. doi: 10.1016/j.brainres.2019.04.017. [Epub ahead of print]


The effect of geodemographic factors on the attendance rates at a regional diabetic retinopathy treatment centre.

Greenan E, Salim M, Coakley DN, James M.

Ir J Med Sci. 2019 Apr 18. doi: 10.1007/s11845-019-02009-4. [Epub ahead of print]


Ab initio study of negative electron affinity from light metals on the oxygen-terminated diamond (1 1 1) surface.

James MC, May PW, Allan NL.

J Phys Condens Matter. 2019 Jul 24;31(29):295002. doi: 10.1088/1361-648X/ab18ef. Epub 2019 Apr 12.


Visible-Light-Mediated Charge Transfer Enables C-C Bond Formation with Traceless Acceptor Groups.

James MJ, Strieth-Kalthoff F, Sandfort F, Klauck FJR, Wagener F, Glorius F.

Chemistry. 2019 Apr 11. doi: 10.1002/chem.201901397. [Epub ahead of print]


[18F]-SuPAR: A Radiofluorinated Probe for Noninvasive Imaging of DNA Damage-Dependent Poly(ADP-ribose) Polymerase Activity.

Shuhendler AJ, Cui L, Chen Z, Shen B, Chen M, James ML, Witney TH, Bazalova-Carter M, Gambhir SS, Chin FT, Graves EE, Rao J.

Bioconjug Chem. 2019 May 15;30(5):1331-1342. doi: 10.1021/acs.bioconjchem.9b00089. Epub 2019 Apr 22.


Identifying Needs for Self-management Interventions for Adults With CKD and Their Caregivers: A Qualitative Study.

Donald M, Beanlands H, Straus S, Ronksley P, Tam-Tham H, Finlay J, MacKay J, Elliott M, Herrington G, Harwood L, Large CA, Large CL, Waldvogel B, Sparkes D, Delgado M, Tong A, Grill A, Novak M, James MT, Brimble KS, Samuel S, Hemmelgarn BR.

Am J Kidney Dis. 2019 Apr 2. pii: S0272-6386(19)30163-5. doi: 10.1053/j.ajkd.2019.02.006. [Epub ahead of print]


Incidence and Prognosis of Acute Kidney Diseases and Disorders Using an Integrated Approach to Laboratory Measurements in a Universal Health Care System.

James MT, Levey AS, Tonelli M, Tan Z, Barry R, Pannu N, Ravani P, Klarenbach SW, Manns BJ, Hemmelgarn BR.

JAMA Netw Open. 2019 Apr 5;2(4):e191795. doi: 10.1001/jamanetworkopen.2019.1795.


Sulfonation and glucuronidation of hydroxylated bromodiphenyl ethers in human liver.

Cisneros KV, Agarwal V, James MO.

Chemosphere. 2019 Jul;226:132-139. doi: 10.1016/j.chemosphere.2019.03.103. Epub 2019 Mar 20.


Statin use and the risk of acute kidney injury in older adults.

Tonelli M, Lloyd AM, Bello AK, James MT, Klarenbach SW, McAlister FA, Manns BJ, Tsuyuki RT, Hemmelgarn BR; Alberta Kidney Disease Network.

BMC Nephrol. 2019 Mar 25;20(1):103. doi: 10.1186/s12882-019-1280-7.


Deferoxamine mesylate in patients with intracerebral haemorrhage (i-DEF): a multicentre, randomised, placebo-controlled, double-blind phase 2 trial.

Selim M, Foster LD, Moy CS, Xi G, Hill MD, Morgenstern LB, Greenberg SM, James ML, Singh V, Clark WM, Norton C, Palesch YY, Yeatts SD; i-DEF Investigators.

Lancet Neurol. 2019 May;18(5):428-438. doi: 10.1016/S1474-4422(19)30069-9. Epub 2019 Mar 18.


Responsiveness of hypothalamo-pituitary-adrenal axis to leptin is impaired in diet-induced obese rats.

Shin AC, MohanKumar SMJ, Balasubramanian P, Sirivelu MP, Linning K, Woolcock A, James M, MohanKumar PS.

Nutr Diabetes. 2019 Mar 18;9(1):10. doi: 10.1038/s41387-019-0076-y.


Microglial Modulation as a Target for Chronic Pain: From the Bench to the Bedside and Back.

Haight ES, Forman TE, Cordonnier SA, James ML, Tawfik VL.

Anesth Analg. 2019 Apr;128(4):737-746. doi: 10.1213/ANE.0000000000004033.


Planning and Providing Acute Stroke Care in England: The Effect of Planning Footprint Size.

Allen M, Pearn K, Villeneuve E, James M, Stein K.

Front Neurol. 2019 Feb 27;10:150. doi: 10.3389/fneur.2019.00150. eCollection 2019.


Red cell distribution width associations with clinical outcomes: A population-based cohort study.

Tonelli M, Wiebe N, James MT, Naugler C, Manns BJ, Klarenbach SW, Hemmelgarn BR.

PLoS One. 2019 Mar 13;14(3):e0212374. doi: 10.1371/journal.pone.0212374. eCollection 2019.


Three-dimensional functional workspace of thumb prehension.

Curran PF, Bagley AM, Sison-Williamson M, James MA.

Clin Biomech (Bristol, Avon). 2019 Mar;63:63-72. doi: 10.1016/j.clinbiomech.2019.02.017. Epub 2019 Feb 27.


Ophthalmic outcomes following neonatal hypoxic ischaemic encephalopathy; oculomotor, biometric and refractive data in early childhood.

James M, Connor CMO, Cullinane A, Murray DM, Boylan GB.

Eye (Lond). 2019 Mar 5. doi: 10.1038/s41433-019-0390-6. [Epub ahead of print]


CFTR dysfunction increases endoglin and TGF-β signaling in airway epithelia.

Nicola T, Kabir FL, Coric T, Wall SB, Zhang W, James M, MacEwen M, Ren C, Halloran B, Ambalavanan N, Harris WT.

Physiol Rep. 2019 Feb;7(4):e13977. doi: 10.14814/phy2.13977.


Phase II metabolism of betulin by rat and human UDP-glucuronosyltransferases and sulfotransferases.

Hu Z, Wang Z, Luo S, James MO, Wang Y.

Chem Biol Interact. 2019 Apr 1;302:190-195. doi: 10.1016/j.cbi.2019.02.009. Epub 2019 Feb 15.


A stepped wedge cluster randomised trial of a cognitive remediation intervention in alcohol and other drug (AOD) residential treatment services.

Berry J, Jacomb I, Lunn J, Sedwell A, Shakeshaft A, Kelly PJ, Sarrami P, James M, Russell S, Nardo T, Barker D, Holmes J.

BMC Psychiatry. 2019 Feb 13;19(1):70. doi: 10.1186/s12888-019-2044-4.


Blood biochemistry and haematology of migrating loggerhead turtles (Caretta caretta) in the Northwest Atlantic: reference intervals and intra-population comparisons.

Yang T, Haas HL, Patel S, Smolowitz R, James MC, Williard AS.

Conserv Physiol. 2019 Feb 7;7(1):coy079. doi: 10.1093/conphys/coy079. eCollection 2019.


Efficacy and safety of minimally invasive surgery with thrombolysis in intracerebral haemorrhage evacuation (MISTIE III): a randomised, controlled, open-label, blinded endpoint phase 3 trial.

Hanley DF, Thompson RE, Rosenblum M, Yenokyan G, Lane K, McBee N, Mayo SW, Bistran-Hall AJ, Gandhi D, Mould WA, Ullman N, Ali H, Carhuapoma JR, Kase CS, Lees KR, Dawson J, Wilson A, Betz JF, Sugar EA, Hao Y, Avadhani R, Caron JL, Harrigan MR, Carlson AP, Bulters D, LeDoux D, Huang J, Cobb C, Gupta G, Kitagawa R, Chicoine MR, Patel H, Dodd R, Camarata PJ, Wolfe S, Stadnik A, Money PL, Mitchell P, Sarabia R, Harnof S, Barzo P, Unterberg A, Teitelbaum JS, Wang W, Anderson CS, Mendelow AD, Gregson B, Janis S, Vespa P, Ziai W, Zuccarello M, Awad IA; MISTIE III Investigators.

Lancet. 2019 Mar 9;393(10175):1021-1032. doi: 10.1016/S0140-6736(19)30195-3. Epub 2019 Feb 7. Erratum in: Lancet. 2019 Apr 20;393(10181):1596.


Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label, blinded-endpoint, phase 3 trial.

Anderson CS, Huang Y, Lindley RI, Chen X, Arima H, Chen G, Li Q, Billot L, Delcourt C, Bath PM, Broderick JP, Demchuk AM, Donnan GA, Durham AC, Lavados PM, Lee TH, Levi C, Martins SO, Olavarria VV, Pandian JD, Parsons MW, Pontes-Neto OM, Ricci S, Sato S, Sharma VK, Silva F, Song L, Thang NH, Wardlaw JM, Wang JG, Wang X, Woodward M, Chalmers J, Robinson TG; ENCHANTED Investigators and Coordinators.

Lancet. 2019 Mar 2;393(10174):877-888. doi: 10.1016/S0140-6736(19)30038-8. Epub 2019 Feb 7.


Validation of a Model for Identification of Patients With Compensated Cirrhosis at High Risk of Decompensation.

Guha IN, Harris R, Berhane S, Dillon A, Coffey L, James MW, Cucchetti A, Harman DJ, Aithal GP, Elshaarawy O, Waked I, Stewart S, Johnson PJ.

Clin Gastroenterol Hepatol. 2019 Feb 1. pii: S1542-3565(19)30089-8. doi: 10.1016/j.cgh.2019.01.042. [Epub ahead of print]


A New Role for SAG12 Cysteine Protease in Roots of Arabidopsis thaliana.

James M, Masclaux-Daubresse C, Marmagne A, Azzopardi M, Laîné P, Goux D, Etienne P, Trouverie J.

Front Plant Sci. 2019 Jan 11;9:1998. doi: 10.3389/fpls.2018.01998. eCollection 2018.


Clinical and economic outcomes of remotely delivered cognitive behaviour therapy versus treatment as usual for repeat unscheduled care users with severe health anxiety: a multicentre randomised controlled trial.

Morriss R, Patel S, Malins S, Guo B, Higton F, James M, Wu M, Brown P, Boycott N, Kaylor-Hughes C, Morris M, Rowley E, Simpson J, Smart D, Stubley M, Kai J, Tyrer H.

BMC Med. 2019 Jan 23;17(1):16. doi: 10.1186/s12916-019-1253-5.


Survival and Thermal Resistance of Salmonella Enteritidis PT 30 on Almonds after Long-Term Storage.

Limcharoenchat P, James MK, Marks BP.

J Food Prot. 2019 Feb;82(2):194-199. doi: 10.4315/0362-028X.JFP-18-152.


Conservation and restoration of a keystone species: Understanding the settlement preferences of the European oyster (Ostrea edulis).

Rodriguez-Perez A, James M, Donnan DW, Henry TB, Møller LF, Sanderson WG.

Mar Pollut Bull. 2019 Jan;138:312-321. doi: 10.1016/j.marpolbul.2018.11.032. Epub 2018 Nov 27.


Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.

Chauhan G, Adams HHH, Satizabal CL, Bis JC, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith AV, Jian X, Malik R, Traylor M, Pulit SL, Amouyel P, Mazoyer B, Zhu YC, Kaffashian S, Schilling S, Beecham GW, Montine TJ, Schellenberg GD, Kjartansson O, Guðnason V, Knopman DS, Griswold ME, Windham BG, Gottesman RF, Mosley TH, Schmidt R, Saba Y, Schmidt H, Takeuchi F, Yamaguchi S, Nabika T, Kato N, Rajan KB, Aggarwal NT, De Jager PL, Evans DA, Psaty BM, Rotter JI, Rice K, Lopez OL, Liao J, Chen C, Cheng CY, Wong TY, Ikram MK, van der Lee SJ, Amin N, Chouraki V, DeStefano AL, Aparicio HJ, Romero JR, Maillard P, DeCarli C, Wardlaw JM, Hernández MDCV, Luciano M, Liewald D, Deary IJ, Starr JM, Bastin ME, Muñoz Maniega S, Slagboom PE, Beekman M, Deelen J, Uh HW, Lemmens R, Brodaty H, Wright MJ, Ames D, Boncoraglio GB, Hopewell JC, Beecham AH, Blanton SH, Wright CB, Sacco RL, Wen W, Thalamuthu A, Armstrong NJ, Chong E, Schofield PR, Kwok JB, van der Grond J, Stott DJ, Ford I, Jukema JW, Vernooij MW, Hofman A, Uitterlinden AG, van der Lugt A, Wittfeld K, Grabe HJ, Hosten N, von Sarnowski B, Völker U, Levi C, Jimenez-Conde J, Sharma P, Sudlow CLM, Rosand J, Woo D, Cole JW, Meschia JF, Slowik A, Thijs V, Lindgren A, Melander O, Grewal RP, Rundek T, Rexrode K, Rothwell PM, Arnett DK, Jern C, Johnson JA, Benavente OR, Wasssertheil-Smoller S, Lee JM, Wong Q, Mitchell BD, Rich SS, McArdle PF, Geerlings MI, van der Graaf Y, de Bakker PIW, Asselbergs FW, Srikanth V, Thomson R, McWhirter R, Moran C, Callisaya M, Phan T, Rutten-Jacobs LCA, Bevan S, Tzourio C, Mather KA, Sachdev PS, van Duijn CM, Worrall BB, Dichgans M, Kittner SJ, Markus HS, Ikram MA, Fornage M, Launer LJ, Seshadri S, Longstreth WT Jr, Debette S; Stroke Genetics Network (SiGN), the International Stroke Genetics Consortium (ISGC), METASTROKE, Alzheimer's Disease Genetics Consortium (ADGC), and the Neurology Working Group of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium.

Neurology. 2019 Jan 16. pii: 10.1212/WNL.0000000000006851. doi: 10.1212/WNL.0000000000006851. [Epub ahead of print]


Comparison of the Complexity of Patients Seen by Different Medical Subspecialists in a Universal Health Care System.

Tonelli M, Wiebe N, Manns BJ, Klarenbach SW, James MT, Ravani P, Pannu N, Himmelfarb J, Hemmelgarn BR.

JAMA Netw Open. 2018 Nov 2;1(7):e184852. doi: 10.1001/jamanetworkopen.2018.4852. Erratum in: JAMA Netw Open. 2019 Mar 1;2(3):e190147.


Turning the Tide against Antibiotic Resistance by Evaluating Novel, Halogenated Phenazine, Quinoline, and NH125 Compounds against Ureaplasma Species Clinical Isolates and Mycoplasma Type Strains.

Valentine-King MA, Cisneros K, James MO, Huigens RW 3rd, Brown MB.

Antimicrob Agents Chemother. 2019 Feb 26;63(3). pii: e02265-18. doi: 10.1128/AAC.02265-18. Print 2019 Mar.


Assessment of disease progression in dysferlinopathy: A 1-year cohort study.

Moore U, Jacobs M, James MK, Mayhew AG, Fernandez-Torron R, Feng J, Cnaan A, Eagle M, Bettinson K, Rufibach LE, Lofra RM, Blamire AM, Carlier PG, Mittal P, Lowes LP, Alfano L, Rose K, Duong T, Berry KM, Montiel-Morillo E, Pedrosa-Hernández I, Holsten S, Sanjak M, Ashida A, Sakamoto C, Tateishi T, Yajima H, Canal A, Ollivier G, Decostre V, Mendez JB, Sánchez-Aguilera Praxedes N, Thiele S, Siener C, Shierbecker J, Florence JM, Vandevelde B, DeWolf B, Hutchence M, Gee R, Prügel J, Maron E, Hilsden H, Lochmüller H, Grieben U, Spuler S, Tesi Rocha C, Day JW, Jones KJ, Bharucha-Goebel DX, Salort-Campana E, Harms M, Pestronk A, Krause S, Schreiber-Katz O, Walter MC, Paradas C, Hogrel JY, Stojkovic T, Takeda S, Mori-Yoshimura M, Bravver E, Sparks S, Díaz-Manera J, Bello L, Semplicini C, Pegoraro E, Mendell JR, Bushby K, Straub V; Jain COS Consortium.

Neurology. 2019 Jan 9. pii: 10.1212/WNL.0000000000006858. doi: 10.1212/WNL.0000000000006858. [Epub ahead of print]

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