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Items: 1 to 50 of 125

1.

Liraglutide attenuates cardiac remodeling and improves heart function after abdominal aortic constriction through blocking angiotensin II type 1 receptor in rats.

Zheng RH, Bai XJ, Zhang WW, Wang J, Bai F, Yan CP, James EA, Bose HS, Wang NP, Zhao ZQ.

Drug Des Devel Ther. 2019 Aug 6;13:2745-2757. doi: 10.2147/DDDT.S213910. eCollection 2019.

2.

Discriminative T cell recognition of cross-reactive islet-antigens is associated with HLA-DQ8 transdimer-mediated autoimmune diabetes.

Chow IT, Gates TJ, Papadopoulos GK, Moustakas AK, Kolawole EM, Notturno RJ, McGinty JW, Torres-Chinn N, James EA, Greenbaum C, Nepom GT, Evavold BD, Kwok WW.

Sci Adv. 2019 Aug 21;5(8):eaaw9336. doi: 10.1126/sciadv.aaw9336. eCollection 2019 Aug.

3.

Human CD4+ T Cells Specific for Merkel Cell Polyomavirus Localize to Merkel Cell Carcinomas and Target a Required Oncogenic Domain.

Longino NV, Yang J, Iyer JG, Ibrani D, Chow IT, Laing KJ, Campbell VL, Paulson KG, Kulikauskas RM, Church CD, James EA, Nghiem P, Kwok WW, Koelle DM.

Cancer Immunol Res. 2019 Aug 12. doi: 10.1158/2326-6066.CIR-19-0103. [Epub ahead of print]

PMID:
31405946
4.

Pro-inflammatory histidyl-tRNA synthetase-specific CD4+ T cells in the blood and lung of patients with idiopathic inflammatory myopathies.

Galindo-Feria AS, Albrecht I, Fernandes-Cerqueira C, Notarnicola A, James EA, Herrath J, Dastmalchi M, Sandalova T, Rönnblom L, Jakobsson PJ, Fathi M, Achour A, Grunewald J, Malmström V, Lundberg IE.

Arthritis Rheumatol. 2019 Aug 12. doi: 10.1002/art.41075. [Epub ahead of print]

PMID:
31403245
5.

Primary EBV Infection Induces an Acute Wave of Activated Antigen-Specific Cytotoxic CD4+ T Cells.

Meckiff BJ, Ladell K, McLaren JE, Ryan GB, Leese AM, James EA, Price DA, Long HM.

J Immunol. 2019 Sep 1;203(5):1276-1287. doi: 10.4049/jimmunol.1900377. Epub 2019 Jul 15.

6.

A Novel Approach of Identifying Immunodominant Self and Viral Antigen Cross-Reactive T Cells and Defining the Epitopes They Recognize.

Yang J, Jing L, James EA, Gebe JA, Koelle DM, Kwok WW.

Front Immunol. 2018 Dec 3;9:2811. doi: 10.3389/fimmu.2018.02811. eCollection 2018.

7.

DRB4*01:01 Has a Distinct Motif and Presents a Proinsulin Epitope That Is Recognized in Subjects with Type 1 Diabetes.

James EA, Gillette L, Durinovic-Bello I, Speake C, Bondinas GP, Moustakas AK, Greenbaum CJ, Papadopoulos GK, Kwok WW.

J Immunol. 2018 Dec 15;201(12):3524-3533. doi: 10.4049/jimmunol.1800723. Epub 2018 Nov 19.

PMID:
30455401
8.

Analysis of pancreatic beta cell specific CD4+ T cells reveals a predominance of proinsulin specific cells.

Blahnik G, Uchtenhagen H, Chow IT, Speake C, Greenbaum C, Kwok WW, James EA.

Cell Immunol. 2019 Jan;335:68-75. doi: 10.1016/j.cellimm.2018.11.004. Epub 2018 Nov 7.

PMID:
30428974
9.

Citrullinated Aggrecan Epitopes as Targets of Autoreactive CD4+ T Cells in Patients With Rheumatoid Arthritis.

Rims C, Uchtenhagen H, Kaplan MJ, Carmona-Rivera C, Carlucci P, Mikecz K, Markovics A, Carlin J, Buckner JH, James EA.

Arthritis Rheumatol. 2019 Apr;71(4):518-528. doi: 10.1002/art.40768. Epub 2019 Mar 8. Erratum in: Arthritis Rheumatol. 2019 Jun;71(6):907.

PMID:
30390384
10.

Protecting functional β cells with a therapeutic peptide.

Marré ML, Piganelli JD, James EA.

Ann Transl Med. 2018 Sep;6(18):372. doi: 10.21037/atm.2018.07.26. No abstract available.

11.

Inflammation-Induced Citrullinated Glucose-Regulated Protein 78 Elicits Immune Responses in Human Type 1 Diabetes.

Buitinga M, Callebaut A, Marques Câmara Sodré F, Crèvecoeur I, Blahnik-Fagan G, Yang ML, Bugliani M, Arribas-Layton D, Marré M, Cook DP, Waelkens E, Mallone R, Piganelli JD, Marchetti P, Mamula MJ, Derua R, James EA, Mathieu C, Overbergh L.

Diabetes. 2018 Nov;67(11):2337-2348. doi: 10.2337/db18-0295.

12.

Peanut-specific T cell responses in patients with different clinical reactivity.

Birrueta G, Tripple V, Pham J, Manohar M, James EA, Kwok WW, Nadeau KC, Sette A, Peters B, Schulten V.

PLoS One. 2018 Oct 10;13(10):e0204620. doi: 10.1371/journal.pone.0204620. eCollection 2018.

13.

Memory T cells specific to citrullinated α-enolase are enriched in the rheumatic joint.

Pieper J, Dubnovitsky A, Gerstner C, James EA, Rieck M, Kozhukh G, Tandre K, Pellegrino S, Gebe JA, Rönnblom L, Sandalova T, Kwok WW, Klareskog L, Buckner JH, Achour A, Malmström V.

J Autoimmun. 2018 Aug;92:47-56. doi: 10.1016/j.jaut.2018.04.004. Epub 2018 May 28.

14.

Immune Recognition of β-Cells: Neoepitopes as Key Players in the Loss of Tolerance.

James EA, Pietropaolo M, Mamula MJ.

Diabetes. 2018 Jun;67(6):1035-1042. doi: 10.2337/dbi17-0030. Review.

15.

Modifying Enzymes Are Elicited by ER Stress, Generating Epitopes That Are Selectively Recognized by CD4+ T Cells in Patients With Type 1 Diabetes.

Marre ML, McGinty JW, Chow IT, DeNicola ME, Beck NW, Kent SC, Powers AC, Bottino R, Harlan DM, Greenbaum CJ, Kwok WW, Piganelli JD, James EA.

Diabetes. 2018 Jul;67(7):1356-1368. doi: 10.2337/db17-1166. Epub 2018 Apr 13.

16.

Regulatory CD4+ T Cells Recognize Major Histocompatibility Complex Class II Molecule-Restricted Peptide Epitopes of Apolipoprotein B.

Kimura T, Kobiyama K, Winkels H, Tse K, Miller J, Vassallo M, Wolf D, Ryden C, Orecchioni M, Dileepan T, Jenkins MK, James EA, Kwok WW, Hanna DB, Kaplan RC, Strickler HD, Durkin HG, Kassaye SG, Karim R, Tien PC, Landay AL, Gange SJ, Sidney J, Sette A, Ley K.

Circulation. 2018 Sep 11;138(11):1130-1143. doi: 10.1161/CIRCULATIONAHA.117.031420.

17.

Negative Effects of Makeup Use on Perceptions of Leadership Ability Across Two Ethnicities.

James EA, Jenkins S, Watkins CD.

Perception. 2018 Jan 1:301006618763263. doi: 10.1177/0301006618763263. [Epub ahead of print]

PMID:
29523050
18.

FVIII proteins with a modified immunodominant T-cell epitope exhibit reduced immunogenicity and normal FVIII activity.

Ettinger RA, Liberman JA, Gunasekera D, Puranik K, James EA, Thompson AR, Pratt KP.

Blood Adv. 2018 Feb 27;2(4):309-322. doi: 10.1182/bloodadvances.2017013482.

19.

T cell immunity to Zika virus targets immunodominant epitopes that show cross-reactivity with other Flaviviruses.

Reynolds CJ, Suleyman OM, Ortega-Prieto AM, Skelton JK, Bonnesoeur P, Blohm A, Carregaro V, Silva JS, James EA, Maillère B, Dorner M, Boyton RJ, Altmann DM.

Sci Rep. 2018 Jan 12;8(1):672. doi: 10.1038/s41598-017-18781-1.

20.

Combinatorial detection of autoreactive CD8+ T cells with HLA-A2 multimers: a multi-centre study by the Immunology of Diabetes Society T Cell Workshop.

James EA, Abreu JRF, McGinty JW, Odegard JM, Fillié YE, Hocter CN, Culina S, Ladell K, Price DA, Alkanani A, Rihanek M, Fitzgerald-Miller L, Skowera A, Speake C, Gottlieb P, Davidson HW, Wong FS, Roep B, Mallone R; Immunology of Diabetes Society T Cell Workshop Committee.

Diabetologia. 2018 Mar;61(3):658-670. doi: 10.1007/s00125-017-4508-8. Epub 2017 Dec 1.

PMID:
29196783
21.

Direct Analysis of Insulin-Specific T Cells Provides New Insights.

James EA.

Diabetes. 2017 Dec;66(12):2940-2941. doi: 10.2337/dbi17-0041. No abstract available.

22.

Edaravone inhibits pressure overload-induced cardiac fibrosis and dysfunction by reducing expression of angiotensin II AT1 receptor.

Zhang WW, Bai F, Wang J, Zheng RH, Yang LW, James EA, Zhao ZQ.

Drug Des Devel Ther. 2017 Oct 16;11:3019-3033. doi: 10.2147/DDDT.S144807. eCollection 2017.

23.

Corrigendum: Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted α-Enolase T Cell Epitope in Rheumatoid Arthritis.

Gerstner C, Dubnovitsky A, Sandin C, Kozhukh G, Uchtenhagen H, James EA, Rönnelid J, Ytterberg AJ, Pieper J, Reed E, Tandre K, Rieck M, Zubarev RA, Rönnblom L, Sandalova T, Buckner JH, Achour A, Malmström V.

Front Immunol. 2017 Oct 4;8:1236. doi: 10.3389/fimmu.2017.01236. eCollection 2017.

24.

Streamlined Single Cell TCR Isolation and Generation of Retroviral Vectors for In Vitro and In Vivo Expression of Human TCRs.

Sprouse ML, Blahnik G, Lee T, Tully N, Benarjee P, James EA, Redondo MJ, Bettini ML, Bettini M.

J Vis Exp. 2017 Sep 10;(127). doi: 10.3791/55379.

25.

Human Leukocyte Antigen (HLA)-DRB1*15:01 and HLA-DRB5*01:01 Present Complementary Peptide Repertoires.

Scholz EM, Marcilla M, Daura X, Arribas-Layton D, James EA, Alvarez I.

Front Immunol. 2017 Aug 21;8:984. doi: 10.3389/fimmu.2017.00984. eCollection 2017.

26.

Corrigendum: Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes.

Babon JAB, DeNicola ME, Blodgett DM, Crèvecoeur I, Buttrick TS, Maehr R, Bottino R, Naji A, Kaddis J, Elyaman W, James EA, Haliyur R, Brissova M, Overbergh L, Mathieu C, Delong T, Haskins K, Pugliese A, Campbell-Thompson M, Mathews C, Atkinson MA, Powers AC, Harlan DM, Kent SC.

Nat Med. 2017 Aug 4;23(8):1004. doi: 10.1038/nm0817-1004a. No abstract available.

27.

Genomic diversity guides conservation strategies among rare terrestrial orchid species when taxonomy remains uncertain.

Ahrens CW, Supple MA, Aitken NC, Cantrill DJ, Borevitz JO, James EA.

Ann Bot. 2017 Jun 1;119(8):1267-1277. doi: 10.1093/aob/mcx022.

28.

Identification of Unique Antigenic Determinants in the Amino Terminus of IA-2 (ICA512) in Childhood and Adult Autoimmune Diabetes: New Biomarker Development.

Acevedo-Calado M, James EA, Morran MP, Pietropaolo SL, Ouyang Q, Arribas-Layton D, Songini M, Liguori M, Casu A, Auchus RJ, Huang S, Yu L, Michels A, Gianani R, Pietropaolo M.

Diabetes Care. 2017 Apr;40(4):561-568. doi: 10.2337/dc16-1527. Epub 2017 Feb 7.

29.

Corrigendum: Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes.

Babon JA, DeNicola ME, Blodgett DM, Crèvecoeur I, Buttrick TS, Maehr R, Bottino R, Naji A, Kaddis J, Elyaman W, James EA, Haliyur R, Brissova M, Overbergh L, Mathieu C, Delong T, Haskins K, Pugliese A, Campbell-Thompson M, Mathews C, Atkinson MA, Powers AC, Harlan DM, Kent SC.

Nat Med. 2017 Feb 7;23(2):264. doi: 10.1038/nm0217-264a. No abstract available.

PMID:
28170374
30.

Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted α-Enolase T Cell Epitope in Rheumatoid Arthritis.

Gerstner C, Dubnovitsky A, Sandin C, Kozhukh G, Uchtenhagen H, James EA, Rönnelid J, Ytterberg AJ, Pieper J, Reed E, Tandre K, Rieck M, Zubarev RA, Rönnblom L, Sandalova T, Buckner JH, Achour A, Malmström V.

Front Immunol. 2016 Nov 14;7:494. eCollection 2016. Erratum in: Front Immunol. 2017 Oct 04;8:1236.

31.

Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes.

Babon JA, DeNicola ME, Blodgett DM, Crèvecoeur I, Buttrick TS, Maehr R, Bottino R, Naji A, Kaddis J, Elyaman W, James EA, Haliyur R, Brissova M, Overbergh L, Mathieu C, Delong T, Haskins K, Pugliese A, Campbell-Thompson M, Mathews C, Atkinson MA, Powers AC, Harlan DM, Kent SC.

Nat Med. 2016 Dec;22(12):1482-1487. doi: 10.1038/nm.4203. Epub 2016 Oct 31. Erratum in: Nat Med. 2017 Feb 7;23 (2):264. Nat Med. 2017 Aug 4;23 (8):1004.

32.

Rapid identification and expression of human TCRs in retrogenic mice.

Sprouse ML, Blahnik G, Lee T, Tully N, Banerjee P, James EA, Redondo MJ, Bettini ML, Bettini M.

J Immunol Methods. 2016 Dec;439:29-36. doi: 10.1016/j.jim.2016.08.010. Epub 2016 Aug 31.

33.

Efficient ex vivo analysis of CD4+ T-cell responses using combinatorial HLA class II tetramer staining.

Uchtenhagen H, Rims C, Blahnik G, Chow IT, Kwok WW, Buckner JH, James EA.

Nat Commun. 2016 Aug 30;7:12614. doi: 10.1038/ncomms12614.

34.

Immune recognition of citrullinated epitopes.

Nguyen H, James EA.

Immunology. 2016 Oct;149(2):131-8. doi: 10.1111/imm.12640. Epub 2016 Aug 17. Review.

35.

T cells from hemophilia A subjects recognize the same HLA-restricted FVIII epitope with a narrow TCR repertoire.

Ettinger RA, Paz P, James EA, Gunasekera D, Aswad F, Thompson AR, Matthews DC, Pratt KP.

Blood. 2016 Oct 20;128(16):2043-2054. doi: 10.1182/blood-2015-11-682468. Epub 2016 Jul 28.

36.

A Comparative Analysis of the Peptide Repertoires of HLA-DR Molecules Differentially Associated With Rheumatoid Arthritis.

Scholz E, Mestre-Ferrer A, Daura X, García-Medel N, Carrascal M, James EA, Kwok WW, Canals F, Álvarez I.

Arthritis Rheumatol. 2016 Oct;68(10):2412-21. doi: 10.1002/art.39736.

37.

Using Transcriptomics to Identify Differential Gene Expression in Response to Salinity among Australian Phragmites australis Clones.

Holmes GD, Hall NE, Gendall AR, Boon PI, James EA.

Front Plant Sci. 2016 Apr 13;7:432. doi: 10.3389/fpls.2016.00432. eCollection 2016.

38.

Letter to the Editor, re: article "Factors influencing women's satisfaction with surgical abortion" by Tilles, Denny, Cansino and Creinin.

McLemore MR, Desai S, James EA, Taylor D.

Contraception. 2016 Apr;93(4):372. doi: 10.1016/j.contraception.2015.11.014. No abstract available.

39.

Regional Genetic Structure and Environmental Variables Influence our Conservation Approach for Feather Heads (Ptilotus macrocephalus).

Ahrens CW, James EA.

J Hered. 2016 May;107(3):238-47. doi: 10.1093/jhered/esw009. Epub 2016 Feb 10.

40.

Neuroinvasive West Nile Infection Elicits Elevated and Atypically Polarized T Cell Responses That Promote a Pathogenic Outcome.

James EA, Gates TJ, LaFond RE, Yamamoto S, Ni C, Mai D, Gersuk VH, O'Brien K, Nguyen QA, Zeitner B, Lanteri MC, Norris PJ, Chaussabel D, Malhotra U, Kwok WW.

PLoS Pathog. 2016 Jan 21;12(1):e1005375. doi: 10.1371/journal.ppat.1005375. eCollection 2016 Jan.

41.

Lack of allergy to timothy grass pollen is not a passive phenomenon but associated with the allergen-specific modulation of immune reactivity.

Hinz D, Seumois G, Gholami AM, Greenbaum JA, Lane J, White B, Broide DH, Schulten V, Sidney J, Bakhru P, Oseroff C, Wambre E, James EA, Kwok WW, Peters B, Vijayanand P, Sette A.

Clin Exp Allergy. 2016 May;46(5):705-19. doi: 10.1111/cea.12692.

42.

β cell ER stress and the implications for immunogenicity in type 1 diabetes.

Marré ML, James EA, Piganelli JD.

Front Cell Dev Biol. 2015 Oct 27;3:67. doi: 10.3389/fcell.2015.00067. eCollection 2015. Review.

43.

T cell epitopes and post-translationally modified epitopes in type 1 diabetes.

McGinty JW, Marré ML, Bajzik V, Piganelli JD, James EA.

Curr Diab Rep. 2015 Nov;15(11):90. doi: 10.1007/s11892-015-0657-7. Review.

44.

Central T cell tolerance: Identification of tissue-restricted autoantigens in the thymus HLA-DR peptidome.

Alvarez I, Collado JA, Colobran R, Carrascal M, Ciudad MT, Canals F, James EA, Kwok WW, Gärtner M, Kyewski B, Pujol-Borrell R, Jaraquemada D.

J Autoimmun. 2015 Jun;60:12-9. doi: 10.1016/j.jaut.2015.03.004. Epub 2015 Apr 21.

PMID:
25911201
45.

Recruitment and retention strategies for expert nurses in abortion care provision.

McLemore MR, Levi A, James EA.

Contraception. 2015 Jun;91(6):474-9. doi: 10.1016/j.contraception.2015.02.007. Epub 2015 Feb 21.

46.

Factor VIII gene variants and inhibitor risk in African American hemophilia A patients.

Gunasekera D, Ettinger RA, Nakaya Fletcher S, James EA, Liu M, Barrett JC, Withycombe J, Matthews DC, Epstein MS, Hughes RJ, Pratt KP; Personalized Approaches to Therapies for Hemophilia (PATH) Study Investigators.

Blood. 2015 Aug 13;126(7):895-904. doi: 10.1182/blood-2014-09-599365. Epub 2015 Jan 23.

47.

Women know best--findings from a thematic analysis of 5,214 surveys of abortion care experience.

McLemore MR, Desai S, Freedman L, James EA, Taylor D.

Womens Health Issues. 2014 Nov-Dec;24(6):594-9. doi: 10.1016/j.whi.2014.07.001. Epub 2014 Oct 28.

48.

Assessment of CD4+ T cell responses to glutamic acid decarboxylase 65 using DQ8 tetramers reveals a pathogenic role of GAD65 121-140 and GAD65 250-266 in T1D development.

Chow IT, Yang J, Gates TJ, James EA, Mai DT, Greenbaum C, Kwok WW.

PLoS One. 2014 Nov 18;9(11):e112882. doi: 10.1371/journal.pone.0112882. eCollection 2014.

49.

Autoreactive T cells specific for insulin B:11-23 recognize a low-affinity peptide register in human subjects with autoimmune diabetes.

Yang J, Chow IT, Sosinowski T, Torres-Chinn N, Greenbaum CJ, James EA, Kappler JW, Davidson HW, Kwok WW.

Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):14840-5. doi: 10.1073/pnas.1416864111. Epub 2014 Sep 29.

50.

Characterization of 13 microsatellite markers for Diuris basaltica (Orchidaceae) and related species.

Ahrens CW, James EA.

Appl Plant Sci. 2014 Jan 7;2(1). pii: apps.1300069. doi: 10.3732/apps.1300069. eCollection 2014 Jan.

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