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Items: 1 to 50 of 2194

1.

Outcomes with ibrutinib by line of therapy and post-ibrutinib discontinuation in patients with CLL: phase 3 analysis.

O'Brien SM, Byrd JC, Hillmen P, Coutre S, Brown JR, Barr PM, Barrientos JC, Devereux S, Robak T, Reddy NM, Kipps TJ, Tedeschi A, Cymbalista F, Ghia P, Chang S, Ninomoto J, James DF, Burger JA.

Am J Hematol. 2019 Feb 14. doi: 10.1002/ajh.25436. [Epub ahead of print]

PMID:
30767298
2.

Tumour debulking and reduction in predicted risk of tumour lysis syndrome with single-agent ibrutinib in patients with chronic lymphocytic leukaemia.

Wierda WG, Byrd JC, O'Brien S, Coutre S, Barr PM, Furman RR, Kipps TJ, Burger JA, Stevens DA, Sharman J, Ghia P, Flinn IW, Zhou C, Ninomoto J, James DF, Tam CS.

Br J Haematol. 2019 Feb 10. doi: 10.1111/bjh.15791. [Epub ahead of print] No abstract available.

PMID:
30740654
3.

Intestinal dysmotility in a zebrafish (Danio rerio) shank3a;shank3b mutant model of autism.

James DM, Kozol RA, Kajiwara Y, Wahl AL, Storrs EC, Buxbaum JD, Klein M, Moshiree B, Dallman JE.

Mol Autism. 2019 Jan 31;10:3. doi: 10.1186/s13229-018-0250-4. eCollection 2019.

4.

The Role of Adjuvant Chemotherapy in ypT0N0 Rectal Adenocarcinoma.

Nguyen A, James DR, Dozois EJ, Kelley SR, Mathis KL.

J Gastrointest Surg. 2019 Feb 6. doi: 10.1007/s11605-019-04129-9. [Epub ahead of print]

PMID:
30729373
5.

CHO genome mining for synthetic promoter design.

Johari YB, Brown AJ, Alves CS, Zhou Y, Wright CM, Estes SD, Kshirsagar R, James DC.

J Biotechnol. 2019 Jan 28;294:1-13. doi: 10.1016/j.jbiotec.2019.01.015. [Epub ahead of print]

PMID:
30703471
6.

Comparison of data acquisition methods for the identification and quantification of histone post-translational modifications on a Q Exactive HF hybrid quadrupole Orbitrap mass spectrometer.

Cole J, Hanson EJ, James DC, Dockrell DH, Dickman MJ.

Rapid Commun Mass Spectrom. 2019 Jan 30. doi: 10.1002/rcm.8401. [Epub ahead of print]

PMID:
30701600
7.

An Overview of Canadian Research Activities on Diseases Caused by Phytophthora ramorum: Results, Progress, and Challenges.

Shamoun SF, Rioux D, Callan B, James D, Hamelin RC, Bilodeau GJ, Elliott M, Lévesque CA, Becker E, McKenney D, Pedlar J, Bailey K, Brière SC, Niquidet K, Allen E.

Plant Dis. 2018 Jul;102(7):1218-1233. doi: 10.1094/PDIS-11-17-1730-FE. Epub 2018 Jun 7.

PMID:
30673582
8.

Lower Body Acceleration and Muscular Responses to Rotational and Vertical Whole-Body Vibration at Different Frequencies and Amplitudes.

Zaidell LN, Pollock RD, James DC, Bowtell JL, Newham DJ, Sumners DP, Mileva KN.

Dose Response. 2019 Jan 6;17(1):1559325818819946. doi: 10.1177/1559325818819946. eCollection 2019 Jan-Mar.

9.

Illuminating the dark phosphoproteome.

Needham EJ, Parker BL, Burykin T, James DE, Humphrey SJ.

Sci Signal. 2019 Jan 22;12(565). pii: eaau8645. doi: 10.1126/scisignal.aau8645. Review.

PMID:
30670635
10.

Improving the uptake of prenatal, perinatal and paediatric autopsies.

James D.

BJOG. 2019 Jan 18. doi: 10.1111/1471-0528.15618. [Epub ahead of print] No abstract available.

PMID:
30657627
11.

Fluoromethylcyclopropylamine derivatives as potential in vivo toxicophores - A cautionary disclosure.

Acton B, Small HF, Smith KM, McGonagle A, Stowell AIJ, James DI, Hamilton NM, Hamilton N, Hitchin JR, Hutton CP, Waddell ID, Ogilvie DJ, Jordan AM.

Bioorg Med Chem Lett. 2019 Feb 15;29(4):560-562. doi: 10.1016/j.bmcl.2018.12.066. Epub 2019 Jan 2.

12.

Treating Opioid Dependence: Pain Medicine Physiology of Tolerance and Addiction.

James DL, Jowza M.

Clin Obstet Gynecol. 2019 Mar;62(1):87-97. doi: 10.1097/GRF.0000000000000422.

PMID:
30614846
13.

Modified Ride-on Cars as Early Mobility for Children with Mobility Limitations: A Scoping Review.

James D, Pfaff J, Jeffries LM.

Phys Occup Ther Pediatr. 2018 Dec 28:1-18. doi: 10.1080/01942638.2018.1547808. [Epub ahead of print]

PMID:
30592238
14.

Integrative medicine therapeutic approaches to cancer care: patient preferences from focus groups.

Kim WS, James D, Millstine DM.

Support Care Cancer. 2018 Dec 19. doi: 10.1007/s00520-018-4601-7. [Epub ahead of print]

PMID:
30569264
15.

Hydrogen-Deuterium Exchange Epitope Mapping Reveals Distinct Neutralizing Mechanisms for Two Monoclonal Antibodies against Diphtheria Toxin.

Zhu S, Liuni P, Ettorre L, Chen T, Szeto J, Carpick B, James DA, Wilson DJ.

Biochemistry. 2019 Feb 12;58(6):646-656. doi: 10.1021/acs.biochem.8b01123. Epub 2019 Jan 3.

PMID:
30560647
16.

The Extracellular Matrix of Ovarian Cortical Inclusion Cysts Modulates Invasion of Fallopian Tube Epithelial Cells.

Fleszar AJ, Walker A, Porubsky V, Flanigan W, James D, Campagnola PJ, Weisman PS, Kreeger PK.

APL Bioeng. 2018;2(3). pii: 031902. doi: 10.1063/1.5022595. Epub 2018 Apr 11.

17.

RagC phosphorylation autoregulates mTOR complex 1.

Yang G, Humphrey SJ, Murashige DS, Francis D, Wang QP, Cooke KC, Neely GG, James DE.

EMBO J. 2019 Feb 1;38(3). pii: e99548. doi: 10.15252/embj.201899548. Epub 2018 Dec 14.

PMID:
30552228
18.

Ibrutinib plus obinutuzumab versus chlorambucil plus obinutuzumab in first-line treatment of chronic lymphocytic leukaemia (iLLUMINATE): a multicentre, randomised, open-label, phase 3 trial.

Moreno C, Greil R, Demirkan F, Tedeschi A, Anz B, Larratt L, Simkovic M, Samoilova O, Novak J, Ben-Yehuda D, Strugov V, Gill D, Gribben JG, Hsu E, Lih CJ, Zhou C, Clow F, James DF, Styles L, Flinn IW.

Lancet Oncol. 2019 Jan;20(1):43-56. doi: 10.1016/S1470-2045(18)30788-5. Epub 2018 Dec 3. Erratum in: Lancet Oncol. 2019 Jan;20(1):e10.

PMID:
30522969
19.

Acoustic remote sensing for source localization and atmospheric tomography: Applications of the cross-correlation Green's function retrieval method.

Denis MF, Collier SL, Noble JM, Kirkpatrick Alberts WC 2nd, Ligon DA, Sim LK, James D, Reiff CG.

J Acoust Soc Am. 2018 Nov;144(5):EL465. doi: 10.1121/1.5080461.

PMID:
30522327
20.

Development of a human skeletal micro muscle platform with pacing capabilities.

Mills RJ, Parker BL, Monnot P, Needham EJ, Vivien CJ, Ferguson C, Parton RG, James DE, Porrello ER, Hudson JE.

Biomaterials. 2018 Nov 28. pii: S0142-9612(18)30813-5. doi: 10.1016/j.biomaterials.2018.11.030. [Epub ahead of print]

PMID:
30527761
21.

Does Adult Neurogenesis Persist in the Human Hippocampus?

Paredes MF, Sorrells SF, Cebrian-Silla A, Sandoval K, Qi D, Kelley KW, James D, Mayer S, Chang J, Auguste KI, Chang EF, Gutierrez Martin AJ, Kriegstein AR, Mathern GW, Oldham MC, Huang EJ, Garcia-Verdugo JM, Yang Z, Alvarez-Buylla A.

Cell Stem Cell. 2018 Dec 6;23(6):780-781. doi: 10.1016/j.stem.2018.11.006. No abstract available.

PMID:
30526879
22.

Returning to Sport After Gymnastics Injuries.

Sweeney EA, Howell DR, James DA, Potter MN, Provance AJ.

Curr Sports Med Rep. 2018 Nov;17(11):376-390. doi: 10.1249/JSR.0000000000000533. Review.

PMID:
30407946
23.

Weight Loss Strategies Used by Army Reserve Officer Training Corps Cadets: Implication for Student Health and Wellness Services.

Wilson JA, James DC.

Telemed J E Health. 2018 Nov 8. doi: 10.1089/tmj.2018.0174. [Epub ahead of print]

PMID:
30407124
24.

Green's function extraction by crosscorrelation and multidimensional deconvolution for outdoor sound propagation.

Denis MF, Collier SL, Noble JM, Kirkpatrick Alberts WC 2nd, Ligon DA, Sim LK, James D, Reiff CG.

J Acoust Soc Am. 2018 Oct;144(4):EL353. doi: 10.1121/1.5065072.

PMID:
30404488
25.

Cell-Active Small Molecule Inhibitors of the DNA-Damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides.

Waszkowycz B, Smith KM, McGonagle AE, Jordan AM, Acton B, Fairweather EE, Griffiths LA, Hamilton NM, Hamilton NS, Hitchin JR, Hutton CP, James DI, Jones CD, Jones S, Mould DP, Small HF, Stowell AIJ, Tucker JA, Waddell ID, Ogilvie DJ.

J Med Chem. 2018 Nov 19. doi: 10.1021/acs.jmedchem.8b01407. [Epub ahead of print]

PMID:
30403352
26.

Laser-Induced Graphene: From Discovery to Translation.

Ye R, James DK, Tour JM.

Adv Mater. 2019 Jan;31(1):e1803621. doi: 10.1002/adma.201803621. Epub 2018 Oct 4. Review.

PMID:
30368919
27.

Whole synthetic pathway engineering of recombinant protein production.

Brown AJ, Gibson SJ, Hatton D, Arnall CL, James DC.

Biotechnol Bioeng. 2019 Feb;116(2):375-387. doi: 10.1002/bit.26855. Epub 2018 Nov 5.

PMID:
30345502
28.

A survey of eight hot Jupiters in secondary eclipse using WIRCam at CFHT.

Martioli E, Colón KD, Angerhausen D, Stassun KG, Rodriguez JE, Zhou G, Gaudi BS, Pepper J, Beatty TG, Tata R, James DJ, Eastman JD, Wilson PA, Bayliss D, Stevens DJ.

Mon Not R Astron Soc. 2018 Mar 1;474(3):4264-4277. doi: 10.1093/mnras/stx3009. Epub 2017 Nov 23.

PMID:
30344345
29.

A functional genomics screen reveals a strong synergistic effect between docetaxel and the mitotic gene DLGAP5 that is mediated by the androgen receptor.

Hewit K, Sandilands E, Martinez RS, James D, Leung HY, Bryant DM, Shanks E, Markert EK.

Cell Death Dis. 2018 Oct 19;9(11):1069. doi: 10.1038/s41419-018-1115-7.

30.

Disruption of beta cell acetyl-CoA carboxylase-1 in mice impairs insulin secretion and beta cell mass.

Cantley J, Davenport A, Vetterli L, Nemes NJ, Whitworth PT, Boslem E, Thai LM, Mellett N, Meikle PJ, Hoehn KL, James DE, Biden TJ.

Diabetologia. 2019 Jan;62(1):99-111. doi: 10.1007/s00125-018-4743-7. Epub 2018 Oct 17.

31.

Protein Kinase C Epsilon Deletion in Adipose Tissue, but Not in Liver, Improves Glucose Tolerance.

Brandon AE, Liao BM, Diakanastasis B, Parker BL, Raddatz K, McManus SA, O'Reilly L, Kimber E, van der Kraan AG, Hancock D, Henstridge DC, Meikle PJ, Cooney GJ, James DE, Reibe S, Febbraio MA, Biden TJ, Schmitz-Peiffer C.

Cell Metab. 2019 Jan 8;29(1):183-191.e7. doi: 10.1016/j.cmet.2018.09.013. Epub 2018 Oct 11.

PMID:
30318338
32.

Parameters that remain consistent independent of pausing before gait-initiation during normal rise-to-walk behaviour delineated by sit-to-walk and sit-to-stand-and-walk.

Jones GD, James DC, Thacker M, Green DA.

PLoS One. 2018 Oct 9;13(10):e0205346. doi: 10.1371/journal.pone.0205346. eCollection 2018.

33.

Multistate modeling and simulation of patient trajectories after allogeneic hematopoietic stem cell transplantation to inform drug development.

James DA, Ng J, Wei J, Vandemeulebroecke M.

Biom J. 2018 Sep 17. doi: 10.1002/bimj.201700285. [Epub ahead of print]

PMID:
30295953
34.

Characterizing the kinetics of lymphocytosis in patients with chronic lymphocytic leukemia treated with single-agent ibrutinib.

Barrientos JC, Burger JA, Byrd JC, Hillmen P, Zhou C, Ninomoto J, James DF, Kipps TJ.

Leuk Lymphoma. 2018 Oct 2:1-6. doi: 10.1080/10428194.2018.1512710. [Epub ahead of print]

35.

Management for hydatid cysts of the lung ruptured in the pleural cavity.

Issoufou I, Harmouch H, Belliraj L, Ammor F, Rabiou S, Younssa H, James DL, Lakranbi M, Sani R, Ouadnouni Y, Smahi M.

Med Sante Trop. 2018 Aug 1;28(3):292-296. doi: 10.1684/mst.2018.0818.

36.

Recent Advances on the Multiplex Molecular Detection of Plant Viruses and Viroids.

Pallás V, Sánchez-Navarro JA, James D.

Front Microbiol. 2018 Sep 10;9:2087. doi: 10.3389/fmicb.2018.02087. eCollection 2018. Review.

37.

Improvement in Parameters of Hematologic and Immunologic Function and Patient Well-being in the Phase III RESONATE Study of Ibrutinib Versus Ofatumumab in Patients With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.

Barrientos JC, O'Brien S, Brown JR, Kay NE, Reddy NM, Coutre S, Tam C, Mulligan S, Jaeger U, Devereux S, Pocock C, Robak T, Schuster SJ, Schuh A, Gill D, Bloor A, Dearden C, Moreno C, Cull G, Hamblin M, Jones JA, Eckert K, Solman IG, Suzuki S, Hsu E, James DF, Byrd JC, Hillmen P.

Clin Lymphoma Myeloma Leuk. 2018 Dec;18(12):803-813.e7. doi: 10.1016/j.clml.2018.08.007. Epub 2018 Aug 18.

38.

Multivalent biomaterial platform to control the distinct arterial venous differentiation of pluripotent stem cells.

Dorsey TB, Kim D, Grath A, James D, Dai G.

Biomaterials. 2018 Dec;185:1-12. doi: 10.1016/j.biomaterials.2018.09.002. Epub 2018 Sep 3.

PMID:
30216805
39.

High-throughput and high-sensitivity phosphoproteomics with the EasyPhos platform.

Humphrey SJ, Karayel O, James DE, Mann M.

Nat Protoc. 2018 Sep;13(9):1897-1916. doi: 10.1038/s41596-018-0014-9.

PMID:
30190555
40.

Detection of Residual Proteins UL5 and UL29 Using a Targeted Proteomics Approach in HSV529, a Replication-Deficient HSV-2 Vaccine Candidate.

James DA, Fradin MJ, Pedyczak A, Carpick BW.

J Pharm Sci. 2018 Dec;107(12):3022-3031. doi: 10.1016/j.xphs.2018.08.018. Epub 2018 Aug 31.

PMID:
30176254
41.

Single-agent ibrutinib versus chemoimmunotherapy regimens for treatment-naïve patients with chronic lymphocytic leukemia: A cross-trial comparison of phase 3 studies.

Robak T, Burger JA, Tedeschi A, Barr PM, Owen C, Bairey O, Hillmen P, Simpson D, Grosicki S, Devereux S, McCarthy H, Coutre SE, Quach H, Gaidano G, Maslyak Z, Stevens DA, Moreno C, Gill DS, Flinn IW, Gribben JG, Mokatrin A, Cheng M, Styles L, James DF, Kipps TJ, Ghia P.

Am J Hematol. 2018 Nov;93(11):1402-1410. doi: 10.1002/ajh.25259. Epub 2018 Oct 9.

42.

Exercise-induced molecular mechanisms promoting glycogen supercompensation in human skeletal muscle.

Hingst JR, Bruhn L, Hansen MB, Rosschou MF, Birk JB, Fentz J, Foretz M, Viollet B, Sakamoto K, Færgeman NJ, Havelund JF, Parker BL, James DE, Kiens B, Richter EA, Jensen J, Wojtaszewski JFP.

Mol Metab. 2018 Oct;16:24-34. doi: 10.1016/j.molmet.2018.07.001. Epub 2018 Jul 25.

43.

Developing dual herbicide tolerant transgenic rice plants for sustainable weed management.

Fartyal D, Agarwal A, James D, Borphukan B, Ram B, Sheri V, Agrawal PK, Achary VMM, Reddy MK.

Sci Rep. 2018 Aug 2;8(1):11598. doi: 10.1038/s41598-018-29554-9.

44.

Palliative Care and Stroke: An Integrative Review of the Literature.

Molidor S, Overbaugh KJ, James D, White CL.

J Hosp Palliat Nurs. 2018 Aug;20(4):358-367. doi: 10.1097/NJH.0000000000000450.

PMID:
30063629
45.

Safety Analysis of Four Randomized Controlled Studies of Ibrutinib in Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Mantle Cell Lymphoma.

O'Brien S, Hillmen P, Coutre S, Barr PM, Fraser G, Tedeschi A, Burger JA, Dilhuydy MS, Hess G, Moreno C, Cramer P, Liu E, Chang S, Vermeulen J, Styles L, Howes A, James DF, Patel K, Graef T, Valentino R.

Clin Lymphoma Myeloma Leuk. 2018 Oct;18(10):648-657.e15. doi: 10.1016/j.clml.2018.06.016. Epub 2018 Jun 28.

46.

Muscle and adipose tissue insulin resistance: malady without mechanism?

Fazakerley DJ, Krycer JR, Kearney AL, Hocking SL, James DE.

J Lipid Res. 2018 Jul 27. pii: jlr.R087510. doi: 10.1194/jlr.R087510. [Epub ahead of print]

47.

The effect of Bruton's tyrosine kinase (BTK) inhibitors on collagen-induced platelet aggregation, BTK, and tyrosine kinase expressed in hepatocellular carcinoma (TEC).

Chen J, Kinoshita T, Gururaja T, Sukbuntherng J, James D, Lu D, Whang J, Versele M, Chang BY.

Eur J Haematol. 2018 Jul 20. doi: 10.1111/ejh.13148. [Epub ahead of print]

PMID:
30030853
48.

Low cost sustainable materials for grey water reclamation.

James DTK, Ifelebuegu AO.

Water Sci Technol. 2018 Jul;2017(3):667-678. doi: 10.2166/wst.2018.225.

PMID:
30016284
49.

Quantitative proteomic characterization of cellular pathways associated with altered insulin sensitivity in skeletal muscle following high-fat diet feeding and exercise training.

Kleinert M, Parker BL, Jensen TE, Raun SH, Pham P, Han X, James DE, Richter EA, Sylow L.

Sci Rep. 2018 Jul 16;8(1):10723. doi: 10.1038/s41598-018-28540-5.

50.

Control of amino acid transport into Chinese hamster ovary cells.

Geoghegan D, Arnall C, Hatton D, Noble-Longster J, Sellick C, Senussi T, James DC.

Biotechnol Bioeng. 2018 Dec;115(12):2908-2929. doi: 10.1002/bit.26794. Epub 2018 Oct 5.

PMID:
29987891

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