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Items: 9

1.

The Novel Bromodomain and Extraterminal Domain Inhibitor INCB054329 Induces Vulnerabilities in Myeloma Cells That Inform Rational Combination Strategies.

Stubbs MC, Burn TC, Sparks RB, Maduskuie T, Diamond S, Rupar M, Wen X, Volgina A, Zolotarjova N, Waeltz P, Favata M, Jalluri R, Liu H, Liu XM, Li J, Collins R, Falahatpisheh N, Polam P, DiMatteo D, Feldman P, Dostalik V, Thekkat P, Gardiner C, He X, Li Y, Covington M, Wynn R, Ruggeri B, Yeleswaram S, Xue C, Yao W, Combs AP, Huber R, Hollis G, Scherle P, Liu P.

Clin Cancer Res. 2018 Sep 11. pii: clincanres.0098.2018. doi: 10.1158/1078-0432.CCR-18-0098. [Epub ahead of print]

PMID:
30206163
2.

Mechanism of 1,N2-etheno-2'-deoxyguanosine formation from epoxyaldehydes.

Petrova KV, Jalluri RS, Kozekov ID, Rizzo CJ.

Chem Res Toxicol. 2007 Nov;20(11):1685-92. Epub 2007 Oct 2.

3.

Discovery of a potent, selective, and orally active human epidermal growth factor receptor-2 sheddase inhibitor for the treatment of cancer.

Yao W, Zhuo J, Burns DM, Xu M, Zhang C, Li YL, Qian DQ, He C, Weng L, Shi E, Lin Q, Agrios C, Burn TC, Caulder E, Covington MB, Fridman JS, Friedman S, Katiyar K, Hollis G, Li Y, Liu C, Liu X, Marando CA, Newton R, Pan M, Scherle P, Taylor N, Vaddi K, Wasserman ZR, Wynn R, Yeleswaram S, Jalluri R, Bower M, Zhou BB, Metcalf B.

J Med Chem. 2007 Feb 22;50(4):603-6. Epub 2007 Jan 26.

PMID:
17256836
4.

Lead identification of a potent benzopyranone selective estrogen receptor modulator.

McKie JA, Bhagwat SS, Brady H, Doubleday M, Gayo L, Hickman M, Jalluri RK, Khammungkhune S, Kois A, Mortensen D, Richard N, Sapienza J, Shevlin G, Stein B, Sutherland M.

Bioorg Med Chem Lett. 2004 Jul 5;14(13):3407-10.

PMID:
15177442
5.

2-Substituted paullones: CDK1/cyclin B-inhibiting property and in vitro antiproliferative activity.

Kunick C, Schultz C, Lemcke T, Zaharevitz DW, Gussio R, Jalluri RK, Sausville EA, Leost M, Meijer L.

Bioorg Med Chem Lett. 2000 Mar 20;10(6):567-9.

PMID:
10741555
6.

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