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Items: 1 to 50 of 127

1.

High-Affinity α5β1-Integrin-Selective Bicyclic RGD Peptides Identified via Screening of Designed Random Libraries.

Bernhagen D, Jungbluth V, Gisbert Quilis N, Dostalek J, White PB, Jalink K, Timmerman P.

ACS Comb Sci. 2019 Aug 12;21(8):598-607. doi: 10.1021/acscombsci.9b00081. Epub 2019 Aug 1.

PMID:
31269394
2.

Bicyclic RGD Peptides with Exquisite Selectivity for the Integrin αvβ3 Receptor Using a "Random Design" Approach.

Bernhagen D, Jungbluth V, Quilis NG, Dostalek J, White PB, Jalink K, Timmerman P.

ACS Comb Sci. 2019 Mar 11;21(3):198-206. doi: 10.1021/acscombsci.8b00144. Epub 2019 Jan 26.

PMID:
30624885
3.

TRPM7 residue S1269 mediates cAMP dependence of Ca2+ influx.

Broertjes J, Klarenbeek J, Habani Y, Langeslag M, Jalink K.

PLoS One. 2019 Jan 7;14(1):e0209563. doi: 10.1371/journal.pone.0209563. eCollection 2019.

4.

Reactive astrocytes in multiple sclerosis impair neuronal outgrowth through TRPM7-mediated chondroitin sulfate proteoglycan production.

Kamermans A, Planting KE, Jalink K, van Horssen J, de Vries HE.

Glia. 2019 Jan;67(1):68-77. doi: 10.1002/glia.23526. Epub 2018 Nov 19.

5.

Profilin binding couples chloride intracellular channel protein CLIC4 to RhoA-mDia2 signaling and filopodium formation.

Argenzio E, Klarenbeek J, Kedziora KM, Nahidiazar L, Isogai T, Perrakis A, Jalink K, Moolenaar WH, Innocenti M.

J Biol Chem. 2018 Dec 14;293(50):19161-19176. doi: 10.1074/jbc.RA118.002779. Epub 2018 Oct 31.

6.

Spectral imaging of FRET-based sensors reveals sustained cAMP gradients in three spatial dimensions.

Annamdevula NS, Sweat R, Griswold JR, Trinh K, Hoffman C, West S, Deal J, Britain AL, Jalink K, Rich TC, Leavesley SJ.

Cytometry A. 2018 Oct;93(10):1029-1038. doi: 10.1002/cyto.a.23572. Epub 2018 Sep 3.

PMID:
30176184
7.

Enhancer hubs and loop collisions identified from single-allele topologies.

Allahyar A, Vermeulen C, Bouwman BAM, Krijger PHL, Verstegen MJAM, Geeven G, van Kranenburg M, Pieterse M, Straver R, Haarhuis JHI, Jalink K, Teunissen H, Renkens IJ, Kloosterman WP, Rowland BD, de Wit E, de Ridder J, de Laat W.

Nat Genet. 2018 Aug;50(8):1151-1160. doi: 10.1038/s41588-018-0161-5. Epub 2018 Jul 9.

PMID:
29988121
8.

The value of periprostatic fascia thickness and fascia preservation as prognostic factors of erectile function after nerve-sparing robot-assisted radical prostatectomy.

Grivas N, van der Roest RC, de Korne CM, KleinJan GH, Sikorska K, Schoots IG, Tillier C, van der Broek B, Jalink K, Heijmink SWTJP, Buckle T, van Leeuwen FWB, van der Poel HG.

World J Urol. 2019 Feb;37(2):309-315. doi: 10.1007/s00345-018-2387-3. Epub 2018 Jun 23.

PMID:
29936567
9.

TRPM7 controls mesenchymal features of breast cancer cells by tensional regulation of SOX4.

Kuipers AJ, Middelbeek J, Vrenken K, Pérez-González C, Poelmans G, Klarenbeek J, Jalink K, Trepat X, van Leeuwen FN.

Biochim Biophys Acta Mol Basis Dis. 2018 Jul;1864(7):2409-2419. doi: 10.1016/j.bbadis.2018.04.017. Epub 2018 Apr 21.

10.

Negative regulation of urokinase receptor activity by a GPI-specific phospholipase C in breast cancer cells.

van Veen M, Matas-Rico E, van de Wetering K, Leyton-Puig D, Kedziora KM, De Lorenzi V, Stijf-Bultsma Y, van den Broek B, Jalink K, Sidenius N, Perrakis A, Moolenaar WH.

Elife. 2017 Aug 29;6. pii: e23649. doi: 10.7554/eLife.23649.

11.

Flat clathrin lattices are dynamic actin-controlled hubs for clathrin-mediated endocytosis and signalling of specific receptors.

Leyton-Puig D, Isogai T, Argenzio E, van den Broek B, Klarenbeek J, Janssen H, Jalink K, Innocenti M.

Nat Commun. 2017 Jul 13;8:16068. doi: 10.1038/ncomms16068.

12.

Schwann cells are activated by ATP released from neurons in an in vitro cellular model of Miller Fisher syndrome.

Rodella U, Negro S, Scorzeto M, Bergamin E, Jalink K, Montecucco C, Yuki N, Rigoni M.

Dis Model Mech. 2017 May 1;10(5):597-603. doi: 10.1242/dmm.027870. Epub 2017 Jan 6.

13.

Glycerophosphodiesterase GDE2 Promotes Neuroblastoma Differentiation through Glypican Release and Is a Marker of Clinical Outcome.

Matas-Rico E, van Veen M, Leyton-Puig D, van den Berg J, Koster J, Kedziora KM, Molenaar B, Weerts MJA, de Rink I, Medema RH, Giepmans BNG, Perrakis A, Jalink K, Versteeg R, Moolenaar WH.

Cancer Cell. 2016 Dec 12;30(6):986. doi: 10.1016/j.ccell.2016.11.008. No abstract available.

14.

Glycerophosphodiesterase GDE2 Promotes Neuroblastoma Differentiation through Glypican Release and Is a Marker of Clinical Outcome.

Matas-Rico E, van Veen M, Leyton-Puig D, van den Berg J, Koster J, Kedziora KM, Molenaar B, Weerts MJ, de Rink I, Medema RH, Giepmans BN, Perrakis A, Jalink K, Versteeg R, Moolenaar WH.

Cancer Cell. 2016 Oct 10;30(4):548-562. doi: 10.1016/j.ccell.2016.08.016. Epub 2016 Sep 29. Erratum in: Cancer Cell. 2016 Dec 12;30(6):986.

15.

Hypersensitivity to DNA damage in antephase as a safeguard for genome stability.

Feringa FM, Krenning L, Koch A, van den Berg J, van den Broek B, Jalink K, Medema RH.

Nat Commun. 2016 Aug 26;7:12618. doi: 10.1038/ncomms12618.

16.

The TRPM7 interactome defines a cytoskeletal complex linked to neuroblastoma progression.

Middelbeek J, Vrenken K, Visser D, Lasonder E, Koster J, Jalink K, Clark K, van Leeuwen FN.

Eur J Cell Biol. 2016 Nov;95(11):465-474. doi: 10.1016/j.ejcb.2016.06.008. Epub 2016 Jun 24.

PMID:
27402209
17.

Optimizing Imaging Conditions for Demanding Multi-Color Super Resolution Localization Microscopy.

Nahidiazar L, Agronskaia AV, Broertjes J, van den Broek B, Jalink K.

PLoS One. 2016 Jul 8;11(7):e0158884. doi: 10.1371/journal.pone.0158884. eCollection 2016.

18.

PFA fixation enables artifact-free super-resolution imaging of the actin cytoskeleton and associated proteins.

Leyton-Puig D, Kedziora KM, Isogai T, van den Broek B, Jalink K, Innocenti M.

Biol Open. 2016 Jul 15;5(7):1001-9. doi: 10.1242/bio.019570.

19.

Cholesterol and ORP1L-mediated ER contact sites control autophagosome transport and fusion with the endocytic pathway.

Wijdeven RH, Janssen H, Nahidiazar L, Janssen L, Jalink K, Berlin I, Neefjes J.

Nat Commun. 2016 Jun 10;7:11808. doi: 10.1038/ncomms11808.

20.

ATP Released by Injured Neurons Activates Schwann Cells.

Negro S, Bergamin E, Rodella U, Duregotti E, Scorzeto M, Jalink K, Montecucco C, Rigoni M.

Front Cell Neurosci. 2016 May 23;10:134. doi: 10.3389/fncel.2016.00134. eCollection 2016.

21.

Optotaxis: Caged Lysophosphatidic Acid Enables Optical Control of a Chemotactic Gradient.

Hövelmann F, Kedziora KM, Nadler A, Müller R, Jalink K, Schultz C.

Cell Chem Biol. 2016 May 19;23(5):629-634. doi: 10.1016/j.chembiol.2015.11.019. Epub 2016 May 5.

22.

Invadosomes - shaping actin networks to follow mechanical cues.

Kedziora KM, Isogai T, Jalink K, Innocenti M.

Front Biosci (Landmark Ed). 2016 Jun 1;21:1092-117. Review.

PMID:
27100494
23.

Intracellular tortuosity underlies slow cAMP diffusion in adult ventricular myocytes.

Richards M, Lomas O, Jalink K, Ford KL, Vaughan-Jones RD, Lefkimmiatis K, Swietach P.

Cardiovasc Res. 2016 Jun 1;110(3):395-407. doi: 10.1093/cvr/cvw080. Epub 2016 Apr 18.

24.

siFLIM: single-image frequency-domain FLIM provides fast and photon-efficient lifetime data.

Raspe M, Kedziora KM, van den Broek B, Zhao Q, de Jong S, Herz J, Mastop M, Goedhart J, Gadella TW, Young IT, Jalink K.

Nat Methods. 2016 Jun;13(6):501-4. doi: 10.1038/nmeth.3836. Epub 2016 Apr 18.

PMID:
27088314
25.

Rapid Remodeling of Invadosomes by Gi-coupled Receptors: DISSECTING THE ROLE OF Rho GTPases.

Kedziora KM, Leyton-Puig D, Argenzio E, Boumeester AJ, van Butselaar B, Yin T, Wu YI, van Leeuwen FN, Innocenti M, Jalink K, Moolenaar WH.

J Biol Chem. 2016 Feb 26;291(9):4323-33. doi: 10.1074/jbc.M115.695940. Epub 2016 Jan 6.

26.

Beyond ion-conduction: Channel-dependent and -independent roles of TRP channels during development and tissue homeostasis.

Vrenken KS, Jalink K, van Leeuwen FN, Middelbeek J.

Biochim Biophys Acta. 2016 Jun;1863(6 Pt B):1436-46. doi: 10.1016/j.bbamcr.2015.11.008. Epub 2015 Nov 14. Review.

27.

Genome-wide maps of nuclear lamina interactions in single human cells.

Kind J, Pagie L, de Vries SS, Nahidiazar L, Dey SS, Bienko M, Zhan Y, Lajoie B, de Graaf CA, Amendola M, Fudenberg G, Imakaev M, Mirny LA, Jalink K, Dekker J, van Oudenaarden A, van Steensel B.

Cell. 2015 Sep 24;163(1):134-47. doi: 10.1016/j.cell.2015.08.040. Epub 2015 Sep 10.

28.

Initiation of lamellipodia and ruffles involves cooperation between mDia1 and the Arp2/3 complex.

Isogai T, van der Kammen R, Leyton-Puig D, Kedziora KM, Jalink K, Innocenti M.

J Cell Sci. 2015 Oct 15;128(20):3796-810. doi: 10.1242/jcs.176768. Epub 2015 Sep 8.

29.

The molecular architecture of hemidesmosomes, as revealed with super-resolution microscopy.

Nahidiazar L, Kreft M, van den Broek B, Secades P, Manders EM, Sonnenberg A, Jalink K.

J Cell Sci. 2015 Oct 15;128(20):3714-9. doi: 10.1242/jcs.171892. Epub 2015 Sep 1.

30.

Co-Orientation: Quantifying Simultaneous Co-Localization and Orientational Alignment of Filaments in Light Microscopy.

Nieuwenhuizen RP, Nahidiazar L, Manders EM, Jalink K, Stallinga S, Rieger B.

PLoS One. 2015 Jul 10;10(7):e0131756. doi: 10.1371/journal.pone.0131756. eCollection 2015.

31.

MMP-2/9-Specific Activatable Lifetime Imaging Agent.

Rood MT, Raspe M, ten Hove JB, Jalink K, Velders AH, van Leeuwen FW.

Sensors (Basel). 2015 May 12;15(5):11076-91. doi: 10.3390/s150511076.

32.

The rod domain is not essential for the function of plectin in maintaining tissue integrity.

Ketema M, Secades P, Kreft M, Nahidiazar L, Janssen H, Jalink K, de Pereda JM, Sonnenberg A.

Mol Biol Cell. 2015 Jul 1;26(13):2402-17. doi: 10.1091/mbc.E15-01-0043. Epub 2015 May 13.

33.

Fourth-generation epac-based FRET sensors for cAMP feature exceptional brightness, photostability and dynamic range: characterization of dedicated sensors for FLIM, for ratiometry and with high affinity.

Klarenbeek J, Goedhart J, van Batenburg A, Groenewald D, Jalink K.

PLoS One. 2015 Apr 14;10(4):e0122513. doi: 10.1371/journal.pone.0122513. eCollection 2015.

34.

REV7 counteracts DNA double-strand break resection and affects PARP inhibition.

Xu G, Chapman JR, Brandsma I, Yuan J, Mistrik M, Bouwman P, Bartkova J, Gogola E, Warmerdam D, Barazas M, Jaspers JE, Watanabe K, Pieterse M, Kersbergen A, Sol W, Celie PHN, Schouten PC, van den Broek B, Salman A, Nieuwland M, de Rink I, de Ronde J, Jalink K, Boulton SJ, Chen J, van Gent DC, Bartek J, Jonkers J, Borst P, Rottenberg S.

Nature. 2015 May 28;521(7553):541-544. doi: 10.1038/nature14328. Epub 2015 Mar 23.

35.

TRPM7 maintains progenitor-like features of neuroblastoma cells: implications for metastasis formation.

Middelbeek J, Visser D, Henneman L, Kamermans A, Kuipers AJ, Hoogerbrugge PM, Jalink K, van Leeuwen FN.

Oncotarget. 2015 Apr 20;6(11):8760-76.

36.

Recording intracellular cAMP levels with EPAC-based FRET sensors by fluorescence lifetime imaging.

Raspe M, Klarenbeek J, Jalink K.

Methods Mol Biol. 2015;1294:13-24. doi: 10.1007/978-1-4939-2537-7_2.

PMID:
25783874
37.

Fluorescence resonance energy transfer microscopy (FRET).

Kedziora KM, Jalink K.

Methods Mol Biol. 2015;1251:67-82. doi: 10.1007/978-1-4939-2080-8_5.

PMID:
25391795
38.

CLIC4 regulates cell adhesion and β1 integrin trafficking.

Argenzio E, Margadant C, Leyton-Puig D, Janssen H, Jalink K, Sonnenberg A, Moolenaar WH.

J Cell Sci. 2014 Dec 15;127(Pt 24):5189-203. doi: 10.1242/jcs.150623. Epub 2014 Oct 24.

39.

GqPCR-mediated signalling in the spotlight: from visualization towards dissection and quantification.

Jalink K, Adjobo-Hermans MJ.

Curr Pharm Biotechnol. 2014;15(10):893-915. Review.

PMID:
25248560
40.

Function and regulation of the channel-kinase TRPM7 in health and disease.

Visser D, Middelbeek J, van Leeuwen FN, Jalink K.

Eur J Cell Biol. 2014 Oct;93(10-12):455-65. doi: 10.1016/j.ejcb.2014.07.001. Epub 2014 Jul 8. Review.

PMID:
25073440
41.

An activatable, polarity dependent, dual-luminescent imaging agent with a long luminescence lifetime.

Rood MT, Oikonomou M, Buckle T, Raspe M, Urano Y, Jalink K, Velders AH, van Leeuwen FW.

Chem Commun (Camb). 2014 Sep 4;50(68):9733-6. doi: 10.1039/c4cc04015e.

PMID:
25019263
42.

Dopaminergic modulation of cAMP drives nonlinear plasticity across the Drosophila mushroom body lobes.

Boto T, Louis T, Jindachomthong K, Jalink K, Tomchik SM.

Curr Biol. 2014 Apr 14;24(8):822-31. doi: 10.1016/j.cub.2014.03.021. Epub 2014 Mar 27.

43.

Astral microtubules control redistribution of dynein at the cell cortex to facilitate spindle positioning.

Tame MA, Raaijmakers JA, van den Broek B, Lindqvist A, Jalink K, Medema RH.

Cell Cycle. 2014;13(7):1162-70. doi: 10.4161/cc.28031. Epub 2014 Feb 10.

44.

The fidelity of stochastic single-molecule super-resolution reconstructions critically depends upon robust background estimation.

Hoogendoorn E, Crosby KC, Leyton-Puig D, Breedijk RM, Jalink K, Gadella TW, Postma M.

Sci Rep. 2014 Jan 24;4:3854. doi: 10.1038/srep03854.

45.

The NO/cGMP pathway inhibits transient cAMP signals through the activation of PDE2 in striatal neurons.

Polito M, Klarenbeek J, Jalink K, Paupardin-Tritsch D, Vincent P, Castro LR.

Front Cell Neurosci. 2013 Nov 18;7:211. doi: 10.3389/fncel.2013.00211. eCollection 2013.

46.

TRPM7 triggers Ca2+ sparks and invadosome formation in neuroblastoma cells.

Visser D, Langeslag M, Kedziora KM, Klarenbeek J, Kamermans A, Horgen FD, Fleig A, van Leeuwen FN, Jalink K.

Cell Calcium. 2013 Dec;54(6):404-15. doi: 10.1016/j.ceca.2013.09.003. Epub 2013 Oct 16.

47.

hiFRET: some tailwind for FRET resolves weak protein interactions.

Jalink K.

Nat Methods. 2013 Oct;10(10):947-8. doi: 10.1038/nmeth.2652. No abstract available.

PMID:
24076988
48.

WAPL-mediated removal of cohesin protects against segregation errors and aneuploidy.

Haarhuis JH, Elbatsh AM, van den Broek B, Camps D, Erkan H, Jalink K, Medema RH, Rowland BD.

Curr Biol. 2013 Oct 21;23(20):2071-7. doi: 10.1016/j.cub.2013.09.003. Epub 2013 Sep 19.

49.

Detecting cAMP with an EPAC-based FRET sensor in single living cells.

Klarenbeek J, Jalink K.

Methods Mol Biol. 2014;1071:49-58. doi: 10.1007/978-1-62703-622-1_4.

PMID:
24052379
50.

An introduction to fluorescence imaging techniques geared towards biosensor applications.

Goedhart J, Hink MA, Jalink K.

Methods Mol Biol. 2014;1071:17-28. doi: 10.1007/978-1-62703-622-1_2. Review.

PMID:
24052377

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