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The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA.

Pinto R, Vågbø CB, Jakobsson ME, Kim Y, Baltissen MP, O'Donohue MF, Guzmán UH, Małecki JM, Wu J, Kirpekar F, Olsen JV, Gleizes PE, Vermeulen M, Leidel SA, Slupphaug G, Falnes PØ.

Nucleic Acids Res. 2020 Jan 24;48(2):830-846. doi: 10.1093/nar/gkz1147.


The genomic ancestry of the Scandinavian Battle Axe Culture people and their relation to the broader Corded Ware horizon.

Malmström H, Günther T, Svensson EM, Juras A, Fraser M, Munters AR, Pospieszny Ł, Tõrv M, Lindström J, Götherström A, Storå J, Jakobsson M.

Proc Biol Sci. 2019 Oct 9;286(1912):20191528. doi: 10.1098/rspb.2019.1528. Epub 2019 Oct 9.


Reasons for sleeping difficulties as perceived by adolescents: a content analysis.

Jakobsson M, Josefsson K, Högberg K.

Scand J Caring Sci. 2019 Sep 5. doi: 10.1111/scs.12750. [Epub ahead of print]


Methylation in predicting progression of untreated high-grade cervical intraepithelial neoplasia.

Louvanto K, Aro K, Nedjai B, Bützow R, Jakobsson M, Kalliala I, Dillner J, Nieminen P, Lorincz A.

Clin Infect Dis. 2019 Jul 25. pii: ciz677. doi: 10.1093/cid/ciz677. [Epub ahead of print]


Genetic Affinities among Southern Africa Hunter-Gatherers and the Impact of Admixing Farmer and Herder Populations.

Vicente M, Jakobsson M, Ebbesen P, Schlebusch CM.

Mol Biol Evol. 2019 Sep 1;36(9):1849-1861. doi: 10.1093/molbev/msz089.


Age-specific HPV type distribution in high-grade cervical disease in screened and unvaccinated women.

Aro K, Nieminen P, Louvanto K, Jakobsson M, Virtanen S, Lehtinen M, Dillner J, Kalliala I.

Gynecol Oncol. 2019 Aug;154(2):354-359. doi: 10.1016/j.ygyno.2019.05.024. Epub 2019 Jun 5.


Copy number determination of the gene for the human pancreatic polypeptide receptor NPY4R using read depth analysis and droplet digital PCR.

Shebanits K, Günther T, Johansson ACV, Maqbool K, Feuk L, Jakobsson M, Larhammar D.

BMC Biotechnol. 2019 Jun 4;19(1):31. doi: 10.1186/s12896-019-0523-9.


Remobilization of Old Permafrost Carbon to Chukchi Sea Sediments During the End of the Last Deglaciation.

Martens J, Wild B, Pearce C, Tesi T, Andersson A, Bröder L, O'Regan M, Jakobsson M, Sköld M, Gemery L, Cronin TM, Semiletov I, Dudarev OV, Gustafsson Ö.

Global Biogeochem Cycles. 2019 Jan;33(1):2-14. doi: 10.1029/2018GB005969. Epub 2019 Jan 3.


Megalithic tombs in western and northern Neolithic Europe were linked to a kindred society.

Sánchez-Quinto F, Malmström H, Fraser M, Girdland-Flink L, Svensson EM, Simões LG, George R, Hollfelder N, Burenhult G, Noble G, Britton K, Talamo S, Curtis N, Brzobohata H, Sumberova R, Götherström A, Storå J, Jakobsson M.

Proc Natl Acad Sci U S A. 2019 May 7;116(19):9469-9474. doi: 10.1073/pnas.1818037116. Epub 2019 Apr 15.


A Person-Centered Prehabilitation Program Based on Cognitive-Behavioral Physical Therapy for Patients Scheduled for Lumbar Fusion Surgery: A Randomized Controlled Trial.

Lotzke H, Brisby H, Gutke A, Hägg O, Jakobsson M, Smeets R, Lundberg M.

Phys Ther. 2019 Aug 1;99(8):1069-1088. doi: 10.1093/ptj/pzz020.


One-minute stair climbing, 50-foot walk, and timed up-and-go were responsive measures for patients with chronic low back pain undergoing lumbar fusion surgery.

Jakobsson M, Brisby H, Gutke A, Lundberg M, Smeets R.

BMC Musculoskelet Disord. 2019 Mar 30;20(1):137. doi: 10.1186/s12891-019-2512-5.


Lessons learnt from anonymized review of cases of peripartum hysterectomy by international experts: A qualitative pilot study.

Jónasdóttir E, Aabakke AJM, Colmorn LB, Jakobsson M, Äyräs O, Baghestan E, Svanvik T, van den Akker T, Bloemenkamp K, van Roosmalen J, Krebs L, Knight M, Langhoff-Roos J; Nordic Obstetric Surveillance System and the International Network of Obstetric Survey Systems.

Acta Obstet Gynecol Scand. 2019 Aug;98(8):955-957. doi: 10.1111/aogs.13601. Epub 2019 Mar 20.


Real-world cost-effectiveness of targeted therapy in metastatic renal cell carcinoma in Sweden: a population-based retrospective analysis.

Redig J, Dalén J, Harmenberg U, Lindskog M, Ljungberg B, Lundstam S, Sandin R, Wahlgren T, Åkerborg Ö, Jakobsson M.

Cancer Manag Res. 2019 Feb 8;11:1289-1297. doi: 10.2147/CMAR.S188849. eCollection 2019.


Ancient genomes suggest the eastern Pontic-Caspian steppe as the source of western Iron Age nomads.

Krzewińska M, Kılınç GM, Juras A, Koptekin D, Chyleński M, Nikitin AG, Shcherbakov N, Shuteleva I, Leonova T, Kraeva L, Sungatov FA, Sultanova AN, Potekhina I, Łukasik S, Krenz-Niedbała M, Dalén L, Sinika V, Jakobsson M, Storå J, Götherström A.

Sci Adv. 2018 Oct 3;4(10):eaat4457. doi: 10.1126/sciadv.aat4457. eCollection 2018 Oct.


McSwan: A joint site frequency spectrum method to detect and date selective sweeps across multiple population genomes.

Tournebize R, Poncet V, Jakobsson M, Vigouroux Y, Manel S.

Mol Ecol Resour. 2019 Jan;19(1):283-295. doi: 10.1111/1755-0998.12957. Epub 2018 Nov 22.


Sleep duration and sleeping difficulties among adolescents: exploring associations with school stress, self-perception and technology use.

Jakobsson M, Josefsson K, Jutengren G, Sandsjö L, Högberg K.

Scand J Caring Sci. 2019 Mar;33(1):197-206. doi: 10.1111/scs.12621. Epub 2018 Oct 12.


Patients with severe low back pain exhibit a low level of physical activity before lumbar fusion surgery: a cross-sectional study.

Lotzke H, Jakobsson M, Gutke A, Hagströmer M, Brisby H, Hägg O, Smeets R, Lundberg M.

BMC Musculoskelet Disord. 2018 Oct 11;19(1):365. doi: 10.1186/s12891-018-2274-5.


Prediction of Objectively Measured Physical Activity and Self-Reported Disability Following Lumbar Fusion Surgery.

Jakobsson M, Brisby H, Gutke A, Hägg O, Lotzke H, Smeets R, Lundberg M.

World Neurosurg. 2019 Jan;121:e77-e88. doi: 10.1016/j.wneu.2018.08.229. Epub 2018 Sep 11.


Genomic and Strontium Isotope Variation Reveal Immigration Patterns in a Viking Age Town.

Krzewińska M, Kjellström A, Günther T, Hedenstierna-Jonson C, Zachrisson T, Omrak A, Yaka R, Kılınç GM, Somel M, Sobrado V, Evans J, Knipper C, Jakobsson M, Storå J, Götherström A.

Curr Biol. 2018 Sep 10;28(17):2730-2738.e10. doi: 10.1016/j.cub.2018.06.053. Epub 2018 Aug 23.


The dual methyltransferase METTL13 targets N terminus and Lys55 of eEF1A and modulates codon-specific translation rates.

Jakobsson ME, Małecki JM, Halabelian L, Nilges BS, Pinto R, Kudithipudi S, Munk S, Davydova E, Zuhairi FR, Arrowsmith CH, Jeltsch A, Leidel SA, Olsen JV, Falnes PØ.

Nat Commun. 2018 Aug 24;9(1):3411. doi: 10.1038/s41467-018-05646-y.


Lessons Learned Developing a Visual Analytics Solution for Investigative Analysis of Scamming Activities.

Koven J, Felix C, Siadati H, Jakobsson M, Bertini E.

IEEE Trans Vis Comput Graph. 2019 Jan;25(1):225-234. doi: 10.1109/TVCG.2018.2865023. Epub 2018 Aug 20.


Mitochondrial genomes reveal an east to west cline of steppe ancestry in Corded Ware populations.

Juras A, Chyleński M, Ehler E, Malmström H, Żurkiewicz D, Włodarczak P, Wilk S, Peška J, Fojtík P, Králík M, Libera J, Bagińska J, Tunia K, Klochko VI, Dabert M, Jakobsson M, Kośko A.

Sci Rep. 2018 Aug 2;8(1):11603. doi: 10.1038/s41598-018-29914-5.


Investigating Holocene human population history in North Asia using ancient mitogenomes.

Kılınç GM, Kashuba N, Yaka R, Sümer AP, Yüncü E, Shergin D, Ivanov GL, Kichigin D, Pestereva K, Volkov D, Mandryka P, Kharinskii A, Tishkin A, Ineshin E, Kovychev E, Stepanov A, Alekseev A, Fedoseeva SA, Somel M, Jakobsson M, Krzewińska M, Storå J, Götherström A.

Sci Rep. 2018 Jun 12;8(1):8969. doi: 10.1038/s41598-018-27325-0.


The Holocene retreat dynamics and stability of Petermann Glacier in northwest Greenland.

Jakobsson M, Hogan KA, Mayer LA, Mix A, Jennings A, Stoner J, Eriksson B, Jerram K, Mohammad R, Pearce C, Reilly B, Stranne C.

Nat Commun. 2018 May 29;9(1):2104. doi: 10.1038/s41467-018-04573-2.


Genomic Analyses of Pre-European Conquest Human Remains from the Canary Islands Reveal Close Affinity to Modern North Africans.

Rodríguez-Varela R, Günther T, Krzewińska M, Storå J, Gillingwater TH, MacCallum M, Arsuaga JL, Dobney K, Valdiosera C, Jakobsson M, Götherström A, Girdland-Flink L.

Curr Biol. 2018 May 21;28(10):1677-1679. doi: 10.1016/j.cub.2018.04.083. No abstract available.


Tales of Human Migration, Admixture, and Selection in Africa.

Schlebusch CM, Jakobsson M.

Annu Rev Genomics Hum Genet. 2018 Aug 31;19:405-428. doi: 10.1146/annurev-genom-083117-021759. Epub 2018 May 4. Review.


Estimating genetic kin relationships in prehistoric populations.

Monroy Kuhn JM, Jakobsson M, Günther T.

PLoS One. 2018 Apr 23;13(4):e0195491. doi: 10.1371/journal.pone.0195491. eCollection 2018.


Four millennia of Iberian biomolecular prehistory illustrate the impact of prehistoric migrations at the far end of Eurasia.

Valdiosera C, Günther T, Vera-Rodríguez JC, Ureña I, Iriarte E, Rodríguez-Varela R, Simões LG, Martínez-Sánchez RM, Svensson EM, Malmström H, Rodríguez L, Bermúdez de Castro JM, Carbonell E, Alday A, Hernández Vera JA, Götherström A, Carretero JM, Arsuaga JL, Smith CI, Jakobsson M.

Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):3428-3433. doi: 10.1073/pnas.1717762115. Epub 2018 Mar 12.


Clinical course of untreated cervical intraepithelial neoplasia grade 2 under active surveillance: systematic review and meta-analysis.

Tainio K, Athanasiou A, Tikkinen KAO, Aaltonen R, Cárdenas J, Hernándes, Glazer-Livson S, Jakobsson M, Joronen K, Kiviharju M, Louvanto K, Oksjoki S, Tähtinen R, Virtanen S, Nieminen P, Kyrgiou M, Kalliala I.

BMJ. 2018 Feb 27;360:k499. doi: 10.1136/bmj.k499. Review.


Regulation of eukaryotic elongation factor 1 alpha (eEF1A) by dynamic lysine methylation.

Jakobsson ME, Małecki J, Falnes PØ.

RNA Biol. 2018 Mar 4;15(3):314-319. doi: 10.1080/15476286.2018.1440875. Epub 2018 Mar 9. Erratum in: RNA Biol. 2018;15(12):1512.


Identification of FAM173B as a protein methyltransferase promoting chronic pain.

Willemen HLDM, Kavelaars A, Prado J, Maas M, Versteeg S, Nellissen LJJ, Tromp J, Gonzalez Cano R, Zhou W, Jakobsson ME, Małecki J, Posthuma G, Habib AM, Heijnen CJ, Falnes PØ, Eijkelkamp N.

PLoS Biol. 2018 Feb 14;16(2):e2003452. doi: 10.1371/journal.pbio.2003452. eCollection 2018 Feb.


Patterns of variation in cis-regulatory regions: examining evidence of purifying selection.

Naidoo T, Sjödin P, Schlebusch C, Jakobsson M.

BMC Genomics. 2018 Jan 26;19(1):95. doi: 10.1186/s12864-017-4422-y.


Population genomics of Mesolithic Scandinavia: Investigating early postglacial migration routes and high-latitude adaptation.

Günther T, Malmström H, Svensson EM, Omrak A, Sánchez-Quinto F, Kılınç GM, Krzewińska M, Eriksson G, Fraser M, Edlund H, Munters AR, Coutinho A, Simões LG, Vicente M, Sjölander A, Jansen Sellevold B, Jørgensen R, Claes P, Shriver MD, Valdiosera C, Netea MG, Apel J, Lidén K, Skar B, Storå J, Götherström A, Jakobsson M.

PLoS Biol. 2018 Jan 9;16(1):e2003703. doi: 10.1371/journal.pbio.2003703. eCollection 2018 Jan.


BedMachine v3: Complete Bed Topography and Ocean Bathymetry Mapping of Greenland From Multibeam Echo Sounding Combined With Mass Conservation.

Morlighem M, Williams CN, Rignot E, An L, Arndt JE, Bamber JL, Catania G, Chauché N, Dowdeswell JA, Dorschel B, Fenty I, Hogan K, Howat I, Hubbard A, Jakobsson M, Jordan TM, Kjeldsen KK, Millan R, Mayer L, Mouginot J, Noël BPY, O'Cofaigh C, Palmer S, Rysgaard S, Seroussi H, Siegert MJ, Slabon P, Straneo F, van den Broeke MR, Weinrebe W, Wood M, Zinglersen KB.

Geophys Res Lett. 2017 Nov 16;44(21):11051-11061. doi: 10.1002/2017GL074954. Epub 2017 Nov 1.


Increased autophagy signaling but not proteasome activity in human skeletal muscle after prolonged low-intensity exercise with negative energy balance.

Moberg M, Hendo G, Jakobsson M, Mattsson CM, Ekblom-Bak E, Flockhart M, Pontén M, Söderlund K, Ekblom B.

Physiol Rep. 2017 Dec;5(23). doi: 10.14814/phy2.13518.


Risk of preterm birth in women with cervical intraepithelial neoplasia grade one: a population-based cohort study.

Heinonen A, Gissler M, Paavonen J, Tapper AM, Jakobsson M.

Acta Obstet Gynecol Scand. 2018 Feb;97(2):135-141. doi: 10.1111/aogs.13256. Epub 2017 Dec 1.


Acoustic Mapping of Thermohaline Staircases in the Arctic Ocean.

Stranne C, Mayer L, Weber TC, Ruddick BR, Jakobsson M, Jerram K, Weidner E, Nilsson J, Gårdfeldt K.

Sci Rep. 2017 Nov 9;7(1):15192. doi: 10.1038/s41598-017-15486-3.


Genomic Analyses of Pre-European Conquest Human Remains from the Canary Islands Reveal Close Affinity to Modern North Africans.

Rodríguez-Varela R, Günther T, Krzewińska M, Storå J, Gillingwater TH, MacCallum M, Arsuaga JL, Dobney K, Valdiosera C, Jakobsson M, Götherström A, Girdland-Flink L.

Curr Biol. 2017 Nov 6;27(21):3396-3402.e5. doi: 10.1016/j.cub.2017.09.059. Epub 2017 Oct 26. Erratum in: Curr Biol. 2018 May 21;28(10 ):1677-1679.


Evidence of marine ice-cliff instability in Pine Island Bay from iceberg-keel plough marks.

Wise MG, Dowdeswell JA, Jakobsson M, Larter RD.

Nature. 2017 Oct 25;550(7677):506-510. doi: 10.1038/nature24458.


Southern African ancient genomes estimate modern human divergence to 350,000 to 260,000 years ago.

Schlebusch CM, Malmström H, Günther T, Sjödin P, Coutinho A, Edlund H, Munters AR, Vicente M, Steyn M, Soodyall H, Lombard M, Jakobsson M.

Science. 2017 Nov 3;358(6363):652-655. doi: 10.1126/science.aao6266. Epub 2017 Sep 28.


Uncovering human METTL12 as a mitochondrial methyltransferase that modulates citrate synthase activity through metabolite-sensitive lysine methylation.

Małecki J, Jakobsson ME, Ho AYY, Moen A, Rustan AC, Falnes PØ.

J Biol Chem. 2017 Oct 27;292(43):17950-17962. doi: 10.1074/jbc.M117.808451. Epub 2017 Sep 8.


A female Viking warrior confirmed by genomics.

Hedenstierna-Jonson C, Kjellström A, Zachrisson T, Krzewińska M, Sobrado V, Price N, Günther T, Jakobsson M, Götherström A, Storå J.

Am J Phys Anthropol. 2017 Dec;164(4):853-860. doi: 10.1002/ajpa.23308. Epub 2017 Sep 8.


Cancer risk of Lichen planus: A cohort study of 13,100 women in Finland.

Halonen P, Jakobsson M, Heikinheimo O, Riska A, Gissler M, Pukkala E.

Int J Cancer. 2018 Jan 1;142(1):18-22. doi: 10.1002/ijc.31025. Epub 2017 Sep 8.


Northeast African genomic variation shaped by the continuity of indigenous groups and Eurasian migrations.

Hollfelder N, Schlebusch CM, Günther T, Babiker H, Hassan HY, Jakobsson M.

PLoS Genet. 2017 Aug 24;13(8):e1006976. doi: 10.1371/journal.pgen.1006976. eCollection 2017 Aug.


Overall survival in Swedish patients with renal cell carcinoma treated in the period 2002 to 2012: Update of the RENCOMP study with subgroup analysis of the synchronous metastatic and elderly populations.

Lindskog M, Wahlgren T, Sandin R, Kowalski J, Jakobsson M, Lundstam S, Ljungberg B, Harmenberg U.

Urol Oncol. 2017 Sep;35(9):541.e15-541.e22. doi: 10.1016/j.urolonc.2017.05.013. Epub 2017 Jun 13.


Methylation of human eukaryotic elongation factor alpha (eEF1A) by a member of a novel protein lysine methyltransferase family modulates mRNA translation.

Jakobsson ME, Malecki J, Nilges BS, Moen A, Leidel SA, Falnes PØ.

Nucleic Acids Res. 2017 Aug 21;45(14):8239-8254. doi: 10.1093/nar/gkx432.


Reply to Lazaridis and Reich: Robust model-based inference of male-biased admixture during Bronze Age migration from the Pontic-Caspian Steppe.

Goldberg A, Günther T, Rosenberg NA, Jakobsson M.

Proc Natl Acad Sci U S A. 2017 May 16;114(20):E3875-E3877. doi: 10.1073/pnas.1704442114. Epub 2017 May 5. No abstract available.


Mode of first delivery and severe maternal complications in the subsequent pregnancy.

Colmorn LB, Krebs L, Klungsøyr K, Jakobsson M, Tapper AM, Gissler M, Lindqvist PG, Källen K, Gottvall K, Bordahl PE, Bjarnadóttir RI, Langhoff-Roos J.

Acta Obstet Gynecol Scand. 2017 Sep;96(9):1053-1062. doi: 10.1111/aogs.13163. Epub 2017 Jun 26.


National Rates of Uterine Rupture are not Associated with Rates of Previous Caesarean Delivery: Results from the Nordic Obstetric Surveillance Study.

Colmorn LB, Langhoff-Roos J, Jakobsson M, Tapper AM, Gissler M, Lindqvist PG, Källen K, Gottvall K, Klungsøyr K, Bøhrdahl P, Bjarnadóttir RI, Krebs L.

Paediatr Perinat Epidemiol. 2017 May;31(3):176-182. doi: 10.1111/ppe.12356. Epub 2017 Apr 20.


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