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Items: 26

1.

From Molecule to Patient: A Biotech Perspective.

Langer R, Jaklenec A, Traverso G, Hartman D.

Clin Pharmacol Ther. 2019 Nov 20. doi: 10.1002/cpt.1676. [Epub ahead of print] No abstract available.

PMID:
31749166
2.

A heat-stable microparticle platform for oral micronutrient delivery.

Anselmo AC, Xu X, Buerkli S, Zeng Y, Tang W, McHugh KJ, Behrens AM, Rosenberg E, Duan AR, Sugarman JL, Zhuang J, Collins J, Lu X, Graf T, Tzeng SY, Rose S, Acolatse S, Nguyen TD, Le X, Guerra AS, Freed LE, Weinstock SB, Sears CB, Nikolic B, Wood L, Welkhoff PA, Oxley JD, Moretti D, Zimmermann MB, Langer R, Jaklenec A.

Sci Transl Med. 2019 Nov 13;11(518). pii: eaaw3680. doi: 10.1126/scitranslmed.aaw3680.

PMID:
31723037
3.

Chiral Supraparticles for Controllable Nanomedicine.

Yeom J, Guimaraes PPG, Ahn HM, Jung BK, Hu Q, McHugh K, Mitchell MJ, Yun CO, Langer R, Jaklenec A.

Adv Mater. 2019 Nov 5:e1903878. doi: 10.1002/adma.201903878. [Epub ahead of print]

PMID:
31686433
4.

Biofilm-Inspired Encapsulation of Probiotics for the Treatment of Complex Infections.

Li Z, Behrens AM, Ginat N, Tzeng SY, Lu X, Sivan S, Langer R, Jaklenec A.

Adv Mater. 2018 Dec;30(51):e1803925. doi: 10.1002/adma.201803925. Epub 2018 Oct 17.

PMID:
30328144
5.

Nanofibrillar Patches of Commensal Skin Bacteria.

Glinel K, Behrens A, Langer RS, Jaklenec A, Jonas AM.

Biomacromolecules. 2019 Jan 14;20(1):102-108. doi: 10.1021/acs.biomac.8b00735. Epub 2018 Jul 19.

PMID:
29979873
6.

Stabilized single-injection inactivated polio vaccine elicits a strong neutralizing immune response.

Tzeng SY, McHugh KJ, Behrens AM, Rose S, Sugarman JL, Ferber S, Langer R, Jaklenec A.

Proc Natl Acad Sci U S A. 2018 Jun 5;115(23):E5269-E5278. doi: 10.1073/pnas.1720970115. Epub 2018 May 21.

7.

Evaporative Cooling Hydrogel Packaging for Storing Biologics Outside of the Cold Chain.

Ferber S, Behrens AM, McHugh KJ, Rosenberg EM, Linehan AR, Sugarman JL, Jayawardena HSN, Langer R, Jaklenec A.

Adv Healthc Mater. 2018 Jul;7(14):e1800220. doi: 10.1002/adhm.201800220. Epub 2018 May 7.

PMID:
29732715
8.

Controlling the Growth of Staphylococcus epidermidis by Layer-By-Layer Encapsulation.

Jonas AM, Glinel K, Behrens A, Anselmo AC, Langer RS, Jaklenec A.

ACS Appl Mater Interfaces. 2018 May 16;10(19):16250-16259. doi: 10.1021/acsami.8b01988. Epub 2018 May 3.

PMID:
29693369
9.

Rapid, Single-Cell Analysis and Discovery of Vectored mRNA Transfection In Vivo with a loxP-Flanked tdTomato Reporter Mouse.

Kauffman KJ, Oberli MA, Dorkin JR, Hurtado JE, Kaczmarek JC, Bhadani S, Wyckoff J, Langer R, Jaklenec A, Anderson DG.

Mol Ther Nucleic Acids. 2018 Mar 2;10:55-63. doi: 10.1016/j.omtn.2017.11.005. Epub 2017 Nov 21.

10.

Biocompatible Semiconductor Quantum Dots as Cancer Imaging Agents.

McHugh KJ, Jing L, Behrens AM, Jayawardena S, Tang W, Gao M, Langer R, Jaklenec A.

Adv Mater. 2018 May;30(18):e1706356. doi: 10.1002/adma.201706356. Epub 2018 Feb 22. Review.

PMID:
29468747
11.

Fabrication of fillable microparticles and other complex 3D microstructures.

McHugh KJ, Nguyen TD, Linehan AR, Yang D, Behrens AM, Rose S, Tochka ZL, Tzeng SY, Norman JJ, Anselmo AC, Xu X, Tomasic S, Taylor MA, Lu J, Guarecuco R, Langer R, Jaklenec A.

Science. 2017 Sep 15;357(6356):1138-1142. doi: 10.1126/science.aaf7447.

12.

Immunogenicity of pulsatile-release PLGA microspheres for single-injection vaccination.

Guarecuco R, Lu J, McHugh KJ, Norman JJ, Thapa LS, Lydon E, Langer R, Jaklenec A.

Vaccine. 2018 May 24;36(22):3161-3168. doi: 10.1016/j.vaccine.2017.05.094. Epub 2017 Jun 19.

13.

Lipid Nanoparticle Assisted mRNA Delivery for Potent Cancer Immunotherapy.

Oberli MA, Reichmuth AM, Dorkin JR, Mitchell MJ, Fenton OS, Jaklenec A, Anderson DG, Langer R, Blankschtein D.

Nano Lett. 2017 Mar 8;17(3):1326-1335. doi: 10.1021/acs.nanolett.6b03329. Epub 2016 Dec 5.

14.

Ultrasound-Mediated Delivery of RNA to Colonic Mucosa of Live Mice.

Schoellhammer CM, Lauwers GY, Goettel JA, Oberli MA, Cleveland C, Park JY, Minahan D, Chen Y, Anderson DG, Jaklenec A, Snapper SB, Langer R, Traverso G.

Gastroenterology. 2017 Apr;152(5):1151-1160. doi: 10.1053/j.gastro.2017.01.002. Epub 2017 Jan 11.

15.

Layer-by-Layer Encapsulation of Probiotics for Delivery to the Microbiome.

Anselmo AC, McHugh KJ, Webster J, Langer R, Jaklenec A.

Adv Mater. 2016 Nov;28(43):9486-9490. doi: 10.1002/adma.201603270. Epub 2016 Sep 12.

16.

Magnetic Multivalent Trehalose Glycopolymer Nanoparticles for the Detection of Mycobacteria.

Chen X, Wu B, Jayawardana KW, Hao N, Jayawardena HS, Langer R, Jaklenec A, Yan M.

Adv Healthc Mater. 2016 Aug;5(16):2007-12. doi: 10.1002/adhm.201600071. Epub 2016 Jun 10.

17.

Thermostabilization of inactivated polio vaccine in PLGA-based microspheres for pulsatile release.

Tzeng SY, Guarecuco R, McHugh KJ, Rose S, Rosenberg EM, Zeng Y, Langer R, Jaklenec A.

J Control Release. 2016 Jul 10;233:101-13. doi: 10.1016/j.jconrel.2016.05.012. Epub 2016 May 11.

18.

mRNA vaccine delivery using lipid nanoparticles.

Reichmuth AM, Oberli MA, Jaklenec A, Langer R, Blankschtein D.

Ther Deliv. 2016;7(5):319-34. doi: 10.4155/tde-2016-0006. Review. Erratum in: Ther Deliv. 2016 Jun;7(6):411.

19.

High Throughput Layer-by-Layer Films for Extracting Film Forming Parameters and Modulating Film Interactions with Cells.

Jaklenec A, Anselmo AC, Hong J, Vegas AJ, Kozminsky M, Langer R, Hammond PT, Anderson DG.

ACS Appl Mater Interfaces. 2016 Jan 27;8(3):2255-61. doi: 10.1021/acsami.5b11081. Epub 2016 Jan 12.

PMID:
26713554
20.

Single-injection vaccines: Progress, challenges, and opportunities.

McHugh KJ, Guarecuco R, Langer R, Jaklenec A.

J Control Release. 2015 Dec 10;219:596-609. doi: 10.1016/j.jconrel.2015.07.029. Epub 2015 Aug 4.

PMID:
26254198
21.

Progress in the tissue engineering and stem cell industry "are we there yet?".

Jaklenec A, Stamp A, Deweerd E, Sherwin A, Langer R.

Tissue Eng Part B Rev. 2012 Jun;18(3):155-66. doi: 10.1089/ten.TEB.2011.0553. Epub 2012 Feb 8.

PMID:
22220809
22.

Great expectations: private sector activity in tissue engineering, regenerative medicine, and stem cell therapeutics.

Lysaght MJ, Jaklenec A, Deweerd E.

Tissue Eng Part A. 2008 Feb;14(2):305-15. doi: 10.1089/tea.2007.0267.

PMID:
18333783
23.

Sequential release of bioactive IGF-I and TGF-beta 1 from PLGA microsphere-based scaffolds.

Jaklenec A, Hinckfuss A, Bilgen B, Ciombor DM, Aaron R, Mathiowitz E.

Biomaterials. 2008 Apr;29(10):1518-25. doi: 10.1016/j.biomaterials.2007.12.004. Epub 2007 Dec 31.

PMID:
18166223
24.

Novel scaffolds fabricated from protein-loaded microspheres for tissue engineering.

Jaklenec A, Wan E, Murray ME, Mathiowitz E.

Biomaterials. 2008 Jan;29(2):185-92. Epub 2007 Oct 24.

PMID:
17950842
25.

Encapsulation of BSA using a modified W/O/O emulsion solvent removal method.

Ciombor DM, Jaklenec A, Liu AZ, Thanos C, Rahman N, Weston P, Aaron R, Mathiowitz E.

J Microencapsul. 2006 Mar;23(2):183-94.

PMID:
16754374
26.

A potential approach for decreasing the burst effect of protein from PLGA microspheres.

Fu K, Harrell R, Zinski K, Um C, Jaklenec A, Frazier J, Lotan N, Burke P, Klibanov AM, Langer R.

J Pharm Sci. 2003 Aug;92(8):1582-91.

PMID:
12884245

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