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Items: 1 to 50 of 62


In situ structure and assembly of the multidrug efflux pump AcrAB-TolC.

Shi X, Chen M, Yu Z, Bell JM, Wang H, Forrester I, Villarreal H, Jakana J, Du D, Luisi BF, Ludtke SJ, Wang Z.

Nat Commun. 2019 Jun 14;10(1):2635. doi: 10.1038/s41467-019-10512-6.


Structures of Qβ virions, virus-like particles, and the Qβ-MurA complex reveal internal coat proteins and the mechanism of host lysis.

Cui Z, Gorzelnik KV, Chang JY, Langlais C, Jakana J, Young R, Zhang J.

Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):11697-11702. doi: 10.1073/pnas.1707102114. Epub 2017 Oct 16.


Structural insights into species-specific features of the ribosome from the human pathogen Mycobacterium tuberculosis.

Yang K, Chang JY, Cui Z, Li X, Meng R, Duan L, Thongchol J, Jakana J, Huwe CM, Sacchettini JC, Zhang J.

Nucleic Acids Res. 2017 Oct 13;45(18):10884-10894. doi: 10.1093/nar/gkx785.


Subunit conformational variation within individual GroEL oligomers resolved by Cryo-EM.

Roh SH, Hryc CF, Jeong HH, Fei X, Jakana J, Lorimer GH, Chiu W.

Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):8259-8264. doi: 10.1073/pnas.1704725114. Epub 2017 Jul 14.


Accurate model annotation of a near-atomic resolution cryo-EM map.

Hryc CF, Chen DH, Afonine PV, Jakana J, Wang Z, Haase-Pettingell C, Jiang W, Adams PD, King JA, Schmid MF, Chiu W.

Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):3103-3108. doi: 10.1073/pnas.1621152114. Epub 2017 Mar 7.


Asymmetric cryo-EM structure of the canonical Allolevivirus Qβ reveals a single maturation protein and the genomic ssRNA in situ.

Gorzelnik KV, Cui Z, Reed CA, Jakana J, Young R, Zhang J.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):11519-11524. Epub 2016 Sep 26.


Quantifying Variability of Manual Annotation in Cryo-Electron Tomograms.

Hecksel CW, Darrow MC, Dai W, Galaz-Montoya JG, Chin JA, Mitchell PG, Chen S, Jakana J, Schmid MF, Chiu W.

Microsc Microanal. 2016 Jun;22(3):487-96. doi: 10.1017/S1431927616000799. Epub 2016 May 26.


A structural model of the genome packaging process in a membrane-containing double stranded DNA virus.

Hong C, Oksanen HM, Liu X, Jakana J, Bamford DH, Chiu W.

PLoS Biol. 2014 Dec 16;12(12):e1002024. doi: 10.1371/journal.pbio.1002024. eCollection 2014 Dec.


A newly isolated reovirus has the simplest genomic and structural organization of any reovirus.

Auguste AJ, Kaelber JT, Fokam EB, Guzman H, Carrington CV, Erasmus JH, Kamgang B, Popov VL, Jakana J, Liu X, Wood TG, Widen SG, Vasilakis N, Tesh RB, Chiu W, Weaver SC.

J Virol. 2015 Jan;89(1):676-87. doi: 10.1128/JVI.02264-14. Epub 2014 Oct 29.


Capsid expansion mechanism of bacteriophage T7 revealed by multistate atomic models derived from cryo-EM reconstructions.

Guo F, Liu Z, Fang PA, Zhang Q, Wright ET, Wu W, Zhang C, Vago F, Ren Y, Jakana J, Chiu W, Serwer P, Jiang W.

Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):E4606-14. doi: 10.1073/pnas.1407020111. Epub 2014 Oct 13.


An atomic model of brome mosaic virus using direct electron detection and real-space optimization.

Wang Z, Hryc CF, Bammes B, Afonine PV, Jakana J, Chen DH, Liu X, Baker ML, Kao C, Ludtke SJ, Schmid MF, Adams PD, Chiu W.

Nat Commun. 2014 Sep 4;5:4808. doi: 10.1038/ncomms5808.


Crystal structure of a nematode-infecting virus.

Guo YR, Hryc CF, Jakana J, Jiang H, Wang D, Chiu W, Zhong W, Tao YJ.

Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12781-6. doi: 10.1073/pnas.1407122111. Epub 2014 Aug 18.


Validated near-atomic resolution structure of bacteriophage epsilon15 derived from cryo-EM and modeling.

Baker ML, Hryc CF, Zhang Q, Wu W, Jakana J, Haase-Pettingell C, Afonine PV, Adams PD, King JA, Jiang W, Chiu W.

Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12301-6. doi: 10.1073/pnas.1309947110. Epub 2013 Jul 9.


Direct electron detection yields cryo-EM reconstructions at resolutions beyond 3/4 Nyquist frequency.

Bammes BE, Rochat RH, Jakana J, Chen DH, Chiu W.

J Struct Biol. 2012 Mar;177(3):589-601. doi: 10.1016/j.jsb.2012.01.008. Epub 2012 Jan 21.


Symmetry-free cryo-EM structures of the chaperonin TRiC along its ATPase-driven conformational cycle.

Cong Y, Schröder GF, Meyer AS, Jakana J, Ma B, Dougherty MT, Schmid MF, Reissmann S, Levitt M, Ludtke SL, Frydman J, Chiu W.

EMBO J. 2012 Feb 1;31(3):720-30. doi: 10.1038/emboj.2011.366. Epub 2011 Nov 1.


4.4 Å cryo-EM structure of an enveloped alphavirus Venezuelan equine encephalitis virus.

Zhang R, Hryc CF, Cong Y, Liu X, Jakana J, Gorchakov R, Baker ML, Weaver SC, Chiu W.

EMBO J. 2011 Aug 9;30(18):3854-63. doi: 10.1038/emboj.2011.261.


The structure of barmah forest virus as revealed by cryo-electron microscopy at a 6-angstrom resolution has detailed transmembrane protein architecture and interactions.

Kostyuchenko VA, Jakana J, Liu X, Haddow AD, Aung M, Weaver SC, Chiu W, Lok SM.

J Virol. 2011 Sep;85(18):9327-33. doi: 10.1128/JVI.05015-11. Epub 2011 Jul 13.


Practical performance evaluation of a 10k × 10k CCD for electron cryo-microscopy.

Bammes BE, Rochat RH, Jakana J, Chiu W.

J Struct Biol. 2011 Sep;175(3):384-93. doi: 10.1016/j.jsb.2011.05.012. Epub 2011 May 17.


Dual action of ATP hydrolysis couples lid closure to substrate release into the group II chaperonin chamber.

Douglas NR, Reissmann S, Zhang J, Chen B, Jakana J, Kumar R, Chiu W, Frydman J.

Cell. 2011 Jan 21;144(2):240-52. doi: 10.1016/j.cell.2010.12.017.


Structural basis for scaffolding-mediated assembly and maturation of a dsDNA virus.

Chen DH, Baker ML, Hryc CF, DiMaio F, Jakana J, Wu W, Dougherty M, Haase-Pettingell C, Schmid MF, Jiang W, Baker D, King JA, Chiu W.

Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1355-60. doi: 10.1073/pnas.1015739108. Epub 2011 Jan 10.


Zernike phase contrast cryo-electron microscopy and tomography for structure determination at nanometer and subnanometer resolutions.

Murata K, Liu X, Danev R, Jakana J, Schmid MF, King J, Nagayama K, Chiu W.

Structure. 2010 Aug 11;18(8):903-12. doi: 10.1016/j.str.2010.06.006.


4.0-A resolution cryo-EM structure of the mammalian chaperonin TRiC/CCT reveals its unique subunit arrangement.

Cong Y, Baker ML, Jakana J, Woolford D, Miller EJ, Reissmann S, Kumar RN, Redding-Johanson AM, Batth TS, Mukhopadhyay A, Ludtke SJ, Frydman J, Chiu W.

Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):4967-72. doi: 10.1073/pnas.0913774107. Epub 2010 Mar 1.


Mechanism of folding chamber closure in a group II chaperonin.

Zhang J, Baker ML, Schröder GF, Douglas NR, Reissmann S, Jakana J, Dougherty M, Fu CJ, Levitt M, Ludtke SJ, Frydman J, Chiu W.

Nature. 2010 Jan 21;463(7279):379-83. doi: 10.1038/nature08701.


Radiation damage effects at four specimen temperatures from 4 to 100 K.

Bammes BE, Jakana J, Schmid MF, Chiu W.

J Struct Biol. 2010 Mar;169(3):331-41. doi: 10.1016/j.jsb.2009.11.001. Epub 2009 Nov 10.


JADAS: a customizable automated data acquisition system and its application to ice-embedded single particles.

Zhang J, Nakamura N, Shimizu Y, Liang N, Liu X, Jakana J, Marsh MP, Booth CR, Shinkawa T, Nakata M, Chiu W.

J Struct Biol. 2009 Jan;165(1):1-9. doi: 10.1016/j.jsb.2008.09.006. Epub 2008 Sep 30.


Achievable resolution from images of biological specimens acquired from a 4k x 4k CCD camera in a 300-kV electron cryomicroscope.

Chen DH, Jakana J, Liu X, Schmid MF, Chiu W.

J Struct Biol. 2008 Jul;163(1):45-52. doi: 10.1016/j.jsb.2008.04.001. Epub 2008 Apr 14.


Backbone structure of the infectious epsilon15 virus capsid revealed by electron cryomicroscopy.

Jiang W, Baker ML, Jakana J, Weigele PR, King J, Chiu W.

Nature. 2008 Feb 28;451(7182):1130-4. doi: 10.1038/nature06665.


Assessing the capabilities of a 4kx4k CCD camera for electron cryo-microscopy at 300kV.

Booth CR, Jakana J, Chiu W.

J Struct Biol. 2006 Dec;156(3):556-63. Epub 2006 Sep 22.


Structure of epsilon15 bacteriophage reveals genome organization and DNA packaging/injection apparatus.

Jiang W, Chang J, Jakana J, Weigele P, King J, Chiu W.

Nature. 2006 Feb 2;439(7076):612-6.


Three-dimensional structure determination of capsid of Aedes albopictus C6/36 cell densovirus.

Cheng L, Chen S, Brannan JM, Jakana J, Zhang Q, Zhou ZH, Zhang J.

Sci China C Life Sci. 2004 Jun;47(3):224-8.


Electron cryo-microscopy of VAT, the archaeal p97/CDC48 homologue from Thermoplasma acidophilum.

Rockel B, Jakana J, Chiu W, Baumeister W.

J Mol Biol. 2002 Apr 12;317(5):673-81.


A 11.5 A single particle reconstruction of GroEL using EMAN.

Ludtke SJ, Jakana J, Song JL, Chuang DT, Chiu W.

J Mol Biol. 2001 Nov 23;314(2):253-62.


The pattern of tegument-capsid interaction in the herpes simplex virus type 1 virion is not influenced by the small hexon-associated protein VP26.

Chen DH, Jakana J, McNab D, Mitchell J, Zhou ZH, Dougherty M, Chiu W, Rixon FJ.

J Virol. 2001 Dec;75(23):11863-7.


Electron cryomicroscopy and bioinformatics suggest protein fold models for rice dwarf virus.

Zhou ZH, Baker ML, Jiang W, Dougherty M, Jakana J, Dong G, Lu G, Chiu W.

Nat Struct Biol. 2001 Oct;8(10):868-73.


Fourier amplitude decay of electron cryomicroscopic images of single particles and effects on structure determination.

Saad A, Ludtke SJ, Jakana J, Rixon FJ, Tsuruta H, Chiu W.

J Struct Biol. 2001 Jan;133(1):32-42.


Seeing the herpesvirus capsid at 8.5 A.

Zhou ZH, Dougherty M, Jakana J, He J, Rixon FJ, Chiu W.

Science. 2000 May 5;288(5467):877-80.


Visualization of the maturation transition in bacteriophage P22 by electron cryomicroscopy.

Zhang Z, Greene B, Thuman-Commike PA, Jakana J, Prevelige PE Jr, King J, Chiu W.

J Mol Biol. 2000 Mar 31;297(3):615-26.


Identification of additional coat-scaffolding interactions in a bacteriophage P22 mutant defective in maturation.

Thuman-Commike PA, Greene B, Jakana J, McGough A, Prevelige PE, Chiu W.

J Virol. 2000 Apr;74(8):3871-3.


The three-dimensional structure of the Limulus acrosomal process: a dynamic actin bundle.

Sherman MB, Jakana J, Sun S, Matsudaira P, Chiu W, Schmid MF.

J Mol Biol. 1999 Nov 19;294(1):139-49.


Visualization of tegument-capsid interactions and DNA in intact herpes simplex virus type 1 virions.

Zhou ZH, Chen DH, Jakana J, Rixon FJ, Chiu W.

J Virol. 1999 Apr;73(4):3210-8.


Visualization of protein-RNA interactions in cytoplasmic polyhedrosis virus.

Zhang H, Zhang J, Yu X, Lu X, Zhang Q, Jakana J, Chen DH, Zhang X, Zhou ZH.

J Virol. 1999 Feb;73(2):1624-9.


Structure of double-shelled rice dwarf virus.

Lu G, Zhou ZH, Baker ML, Jakana J, Cai D, Wei X, Chen S, Gu X, Chiu W.

J Virol. 1998 Nov;72(11):8541-9.


Identification of the sites of interaction between the scaffold and outer shell in herpes simplex virus-1 capsids by difference electron imaging.

Zhou ZH, Macnab SJ, Jakana J, Scott LR, Chiu W, Rixon FJ.

Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):2778-83.


Refinement of herpesvirus B-capsid structure on parallel supercomputers.

Zhou ZH, Chiu W, Haskell K, Spears H Jr, Jakana J, Rixon FJ, Scott LR.

Biophys J. 1998 Jan;74(1):576-88.


A strategy for electron tomographic data collection and crystallographic reconstruction of biological bundles.

Sherman MB, Jakana J, Sun S, Matsudaira P, Chiu W, Schmid MF.

J Struct Biol. 1997 Dec;120(3):245-56.


An atomic model of the outer layer of the bluetongue virus core derived from X-ray crystallography and electron cryomicroscopy.

Grimes JM, Jakana J, Ghosh M, Basak AK, Roy P, Chiu W, Stuart DI, Prasad BV.

Structure. 1997 Jul 15;5(7):885-93.

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