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Items: 1 to 50 of 1181

1.

KTE-X19 CAR T-Cell Therapy in Relapsed or Refractory Mantle-Cell Lymphoma.

Wang M, Munoz J, Goy A, Locke FL, Jacobson CA, Hill BT, Timmerman JM, Holmes H, Jaglowski S, Flinn IW, McSweeney PA, Miklos DB, Pagel JM, Kersten MJ, Milpied N, Fung H, Topp MS, Houot R, Beitinjaneh A, Peng W, Zheng L, Rossi JM, Jain RK, Rao AV, Reagan PM.

N Engl J Med. 2020 Apr 2;382(14):1331-1342. doi: 10.1056/NEJMoa1914347.

PMID:
32242358
2.

Complete response to anti-PD-L1 antibody in a metastatic bladder cancer associated with novel MSH4 mutation and microsatellite instability.

Yang Y, Jain RK, Glenn ST, Xu B, Singh PK, Wei L, Hu Q, Long M, Hutson N, Wang J, Battaglia S, George S.

J Immunother Cancer. 2020 Mar;8(1). pii: e000128. doi: 10.1136/jitc-2019-000128.

3.

Comorbid conditions and GFR predict non-vertebral fractures in patients with diabetes in an ethnic-specific manner.

Jain RK, Weiner MG, Zhao H, Vokes T.

J Clin Endocrinol Metab. 2020 Mar 20. pii: dgaa141. doi: 10.1210/clinem/dgaa141. [Epub ahead of print]

PMID:
32193529
4.

Prognostic Value of Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio in Head and Neck Malignancies.

Seetohul YB, Singh V, Jain RK, Chaudhary AK.

Indian J Otolaryngol Head Neck Surg. 2020 Mar;72(1):128-132. doi: 10.1007/s12070-019-01771-2. Epub 2019 Nov 25.

PMID:
32158669
5.

Seed transmission of a distinct soybean yellow mottle mosaic virus strain identified from India in natural and experimental hosts.

Sandra N, Tripathi A, Dikshit HK, Mandal B, Jain RK.

Virus Res. 2020 Apr 15;280:197903. doi: 10.1016/j.virusres.2020.197903. Epub 2020 Feb 24.

PMID:
32105764
6.

A multiplex PCR assay for rapid identification of major tospovirus vectors reported in India.

Jangra S, Mittal A, Dhall H, Jain RK, Ghosh A.

BMC Genomics. 2020 Feb 18;21(1):170. doi: 10.1186/s12864-020-6560-x.

7.

Antibody-mediated delivery of viral epitopes to tumors harnesses CMV-specific T cells for cancer therapy.

Millar DG, Ramjiawan RR, Kawaguchi K, Gupta N, Chen J, Zhang S, Nojiri T, Ho WW, Aoki S, Jung K, Chen I, Shi F, Heather JM, Shigeta K, Morton LT, Sepulveda S, Wan L, Joseph R, Minogue E, Khatri A, Bardia A, Ellisen LW, Corcoran RB, Hata AN, Pai SI, Jain RK, Fukumura D, Duda DG, Cobbold M.

Nat Biotechnol. 2020 Feb 10. doi: 10.1038/s41587-019-0404-8. [Epub ahead of print]

PMID:
32042168
8.

Improving cancer immunotherapy using nanomedicines: progress, opportunities and challenges.

Martin JD, Cabral H, Stylianopoulos T, Jain RK.

Nat Rev Clin Oncol. 2020 Apr;17(4):251-266. doi: 10.1038/s41571-019-0308-z. Epub 2020 Feb 7. Review.

PMID:
32034288
9.

Combining microenvironment normalization strategies to improve cancer immunotherapy.

Mpekris F, Voutouri C, Baish JW, Duda DG, Munn LL, Stylianopoulos T, Jain RK.

Proc Natl Acad Sci U S A. 2020 Feb 18;117(7):3728-3737. doi: 10.1073/pnas.1919764117. Epub 2020 Feb 3.

10.

A framework for advancing our understanding of cancer-associated fibroblasts.

Sahai E, Astsaturov I, Cukierman E, DeNardo DG, Egeblad M, Evans RM, Fearon D, Greten FR, Hingorani SR, Hunter T, Hynes RO, Jain RK, Janowitz T, Jorgensen C, Kimmelman AC, Kolonin MG, Maki RG, Powers RS, Puré E, Ramirez DC, Scherz-Shouval R, Sherman MH, Stewart S, Tlsty TD, Tuveson DA, Watt FM, Weaver V, Weeraratna AT, Werb Z.

Nat Rev Cancer. 2020 Mar;20(3):174-186. doi: 10.1038/s41568-019-0238-1. Epub 2020 Jan 24. Review.

11.

CCR2 inhibition reduces tumor myeloid cells and unmasks a checkpoint inhibitor effect to slow progression of resistant murine gliomas.

Flores-Toro JA, Luo D, Gopinath A, Sarkisian MR, Campbell JJ, Charo IF, Singh R, Schall TJ, Datta M, Jain RK, Mitchell DA, Harrison JK.

Proc Natl Acad Sci U S A. 2020 Jan 14;117(2):1129-1138. doi: 10.1073/pnas.1910856117. Epub 2019 Dec 26.

PMID:
31879345
12.

Nasal Endoscopy as an Effective Alternative for CT-Scan in Diagnosing Chronic Rhinosinusitis: A Clinical Study and Review of Literature.

Chakraborty P, Jain RK.

Indian J Otolaryngol Head Neck Surg. 2019 Nov;71(Suppl 3):1734-1738. doi: 10.1007/s12070-017-1085-6. Epub 2017 Feb 3.

PMID:
31763235
13.

Penetrating Neck Injuries: from ER to OR.

Jain RK, Chakraborty P, Joshi P, Pradhan S, Kumari R.

Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):352-357. doi: 10.1007/s12070-018-1307-6. Epub 2018 May 12.

PMID:
31741985
14.

Vessel co-option in glioblastoma: emerging insights and opportunities.

Seano G, Jain RK.

Angiogenesis. 2020 Feb;23(1):9-16. doi: 10.1007/s10456-019-09691-z. Epub 2019 Nov 2. Review.

15.

The blood-brain barrier and blood-tumour barrier in brain tumours and metastases.

Arvanitis CD, Ferraro GB, Jain RK.

Nat Rev Cancer. 2020 Jan;20(1):26-41. doi: 10.1038/s41568-019-0205-x. Epub 2019 Oct 10. Review.

PMID:
31601988
16.

Bevacizumab Reduces Permeability and Concurrent Temozolomide Delivery in a Subset of Patients with Recurrent Glioblastoma.

Gerstner ER, Emblem KE, Chang K, Vakulenko-Lagun B, Yen YF, Beers AL, Dietrich J, Plotkin SR, Catana C, Hooker JM, Duda DG, Rosen B, Kalpathy-Cramer J, Jain RK, Batchelor T.

Clin Cancer Res. 2020 Jan 1;26(1):206-212. doi: 10.1158/1078-0432.CCR-19-1739. Epub 2019 Sep 26.

PMID:
31558474
17.

A phase II study of cabozantinib alone or in combination with trastuzumab in breast cancer patients with brain metastases.

Leone JP, Duda DG, Hu J, Barry WT, Trippa L, Gerstner ER, Jain RK, Tan S, Lawler E, Winer EP, Lin NU, Tolaney SM.

Breast Cancer Res Treat. 2020 Jan;179(1):113-123. doi: 10.1007/s10549-019-05445-z. Epub 2019 Sep 20.

PMID:
31541381
18.

Effect of Aflibercept Plus Modified FOLFOX6 Induction Chemotherapy Before Standard Chemoradiotherapy and Surgery in Patients With High-Risk Rectal Adenocarcinoma: The GEMCAD 1402 Randomized Clinical Trial.

Fernández-Martos C, Pericay C, Losa F, García-Carbonero R, Layos L, Rodríguez-Salas N, Martin-Richard M, Alonso-Orduña V, Vera R, Gallego J, Capdevila J, Salud A, Nogué M, Maurel J, Guash I, Montagut C, Lopez C, Macias I, Jain RK, Garcia-Albeniz X.

JAMA Oncol. 2019 Aug 29. doi: 10.1001/jamaoncol.2019.2294. [Epub ahead of print]

PMID:
31465088
19.

Non-invasive diagnosis and monitoring of urothelial bladder cancer: are we there yet?

Jain RK, Grivas P, Pal SK.

BJU Int. 2019 Sep;124(3):361-362. doi: 10.1111/bju.14877. No abstract available.

PMID:
31436040
20.

Clinical Development of PARP Inhibitors in Treating Metastatic Castration-Resistant Prostate Cancer.

Adashek JJ, Jain RK, Zhang J.

Cells. 2019 Aug 9;8(8). pii: E860. doi: 10.3390/cells8080860. Review.

21.

Vascular regulation of antitumor immunity.

Munn LL, Jain RK.

Science. 2019 Aug 9;365(6453):544-545. doi: 10.1126/science.aaw7875. No abstract available.

PMID:
31395771
22.

Dual Programmed Death Receptor-1 and Vascular Endothelial Growth Factor Receptor-2 Blockade Promotes Vascular Normalization and Enhances Antitumor Immune Responses in Hepatocellular Carcinoma.

Shigeta K, Datta M, Hato T, Kitahara S, Chen IX, Matsui A, Kikuchi H, Mamessier E, Aoki S, Ramjiawan RR, Ochiai H, Bardeesy N, Huang P, Cobbold M, Zhu AX, Jain RK, Duda DG.

Hepatology. 2019 Aug 5. doi: 10.1002/hep.30889. [Epub ahead of print]

PMID:
31378984
23.

Diabetes-Related Fracture Risk Is Different in African Americans Compared With Hispanics and Caucasians.

Jain RK, Weiner MG, Zhao H, Williams KJ, Vokes T.

J Clin Endocrinol Metab. 2019 Nov 1;104(11):5729-5736. doi: 10.1210/jc.2019-00931.

PMID:
31369094
24.

A study of attributable variables impacting orthopedic trauma surgical training.

Shukla R, Champawat VS, Jain RK.

Chin J Traumatol. 2019 Oct;22(5):278-280. doi: 10.1016/j.cjtee.2019.05.001. Epub 2019 Jun 20.

25.

Publisher Correction: Probing tumor microenvironment in patients with newly diagnosed glioblastoma during chemoradiation and adjuvant temozolomide with functional MRI.

Ly KI, Vakulenko-Lagun B, Emblem KE, Ou Y, Da X, Betensky RA, Kalpathy-Cramer J, Duda DG, Jain RK, Chi AS, Plotkin SR, Batchelor TT, Sorensen G, Rosen BR, Gerstner ER.

Sci Rep. 2019 Jun 14;9(1):8721. doi: 10.1038/s41598-019-44365-2.

26.

Total Neoadjuvant Therapy With FOLFIRINOX in Combination With Losartan Followed by Chemoradiotherapy for Locally Advanced Pancreatic Cancer: A Phase 2 Clinical Trial.

Murphy JE, Wo JY, Ryan DP, Clark JW, Jiang W, Yeap BY, Drapek LC, Ly L, Baglini CV, Blaszkowsky LS, Ferrone CR, Parikh AR, Weekes CD, Nipp RD, Kwak EL, Allen JN, Corcoran RB, Ting DT, Faris JE, Zhu AX, Goyal L, Berger DL, Qadan M, Lillemoe KD, Talele N, Jain RK, DeLaney TF, Duda DG, Boucher Y, Fernández-Del Castillo C, Hong TS.

JAMA Oncol. 2019 Jul 1;5(7):1020-1027. doi: 10.1001/jamaoncol.2019.0892.

PMID:
31145418
27.

Correction to: Immunotherapy Advances in Urothelial Carcinoma.

Jain RK, Snyders T, Nandagopal L, Garje R, Zakharia Y, Gupta S.

Curr Treat Options Oncol. 2019 May 23;20(7):53. doi: 10.1007/s11864-019-0660-3.

PMID:
31119396
28.

De novo genome sequencing and secretome analysis of Tilletia indica inciting Karnal bunt of wheat provides pathogenesis-related genes.

Gurjar MS, Aggarwal R, Jogawat A, Kulshreshtha D, Sharma S, Solanke AU, Dubey H, Jain RK.

3 Biotech. 2019 Jun;9(6):219. doi: 10.1007/s13205-019-1743-3. Epub 2019 May 20.

PMID:
31114743
29.

Reprogramming the Tumor Microenvironment to Improve Immunotherapy: Emerging Strategies and Combination Therapies.

Datta M, Coussens LM, Nishikawa H, Hodi FS, Jain RK.

Am Soc Clin Oncol Educ Book. 2019 Jan;39:165-174. doi: 10.1200/EDBK_237987. Epub 2019 May 17. Review.

30.

First Draft Genome Sequence of a Pearl Millet Blast Pathogen, Magnaporthe grisea Strain PMg_Dl, Obtained Using PacBio Single-Molecule Real-Time and Illumina NextSeq 500 Sequencing.

Prakash G, Kumar A, Sheoran N, Aggarwal R, Satyavathi CT, Chikara SK, Ghosh A, Jain RK.

Microbiol Resour Announc. 2019 May 16;8(20). pii: e01499-18. doi: 10.1128/MRA.01499-18.

31.

Danger zone of radial nerve in Indian population - A cadaveric study.

Jain RK, Champawat VS, Mandlecha P.

J Clin Orthop Trauma. 2019 May-Jun;10(3):531-534. doi: 10.1016/j.jcot.2018.02.006. Epub 2018 Feb 21.

PMID:
31061584
32.

Role of Apelin in Glioblastoma Vascularization and Invasion after Anti-VEGF Therapy: What Is the Impact on the Immune System?

Amoozgar Z, Jain RK, Duda DG.

Cancer Res. 2019 May 1;79(9):2104-2106. doi: 10.1158/0008-5472.CAN-19-0749.

33.

Reprogramming the microenvironment with tumor-selective angiotensin blockers enhances cancer immunotherapy.

Chauhan VP, Chen IX, Tong R, Ng MR, Martin JD, Naxerova K, Wu MW, Huang P, Boucher Y, Kohane DS, Langer R, Jain RK.

Proc Natl Acad Sci U S A. 2019 May 28;116(22):10674-10680. doi: 10.1073/pnas.1819889116. Epub 2019 Apr 30.

34.

Important caveats of KEYNOTE-045: relevance of these findings in the current and future therapeutic paradigm.

Slongo J, Jain RK, Spiess PE.

Ann Transl Med. 2019 Mar;7(Suppl 1):S23. doi: 10.21037/atm.2019.01.81. No abstract available.

35.

Pharyngeal-Cervical-Brachial Variant of Guillain-Barré Syndrome Following Dengue Infection: A Rare Syndrome with Rare Association.

Pandey RK, Jain RK, Hussain SZ.

Ann Indian Acad Neurol. 2019 Apr-Jun;22(2):240-241. doi: 10.4103/aian.AIAN_253_18.

36.

Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium.

Seano G, Nia HT, Emblem KE, Datta M, Ren J, Krishnan S, Kloepper J, Pinho MC, Ho WW, Ghosh M, Askoxylakis V, Ferraro GB, Riedemann L, Gerstner ER, Batchelor TT, Wen PY, Lin NU, Grodzinsky AJ, Fukumura D, Huang P, Baish JW, Padera TP, Munn LL, Jain RK.

Nat Biomed Eng. 2019 Mar;3(3):230-245. doi: 10.1038/s41551-018-0334-7. Epub 2019 Jan 7.

37.

FOLFOX plus ziv-aflibercept or placebo in first-line metastatic esophagogastric adenocarcinoma: A double-blind, randomized, multicenter phase 2 trial.

Cleary JM, Horick NK, McCleary NJ, Abrams TA, Yurgelun MB, Azzoli CG, Rubinson DA, Brooks GA, Chan JA, Blaszkowsky LS, Clark JW, Goyal L, Meyerhardt JA, Ng K, Schrag D, Savarese DMF, Graham C, Fitzpatrick B, Gibb KA, Boucher Y, Duda DG, Jain RK, Fuchs CS, Enzinger PC.

Cancer. 2019 Jul 1;125(13):2213-2221. doi: 10.1002/cncr.32029. Epub 2019 Mar 26.

PMID:
30913304
38.
39.

Retraction Note: A homing system targets therapeutic T cells to brain cancer.

Samaha H, Pignata A, Fousek K, Ren J, Lam FW, Stossi F, Dubrulle J, Salsman VS, Krishnan S, Hong SH, Baker ML, Shree A, Gad AZ, Shum T, Fukumura D, Byrd TT, Mukherjee M, Marrelli SP, Orange JS, Joseph SK, Sorensen PH, Taylor MD, Hegde M, Mamonkin M, Jain RK, El-Naggar S, Ahmed N.

Nature. 2019 Mar;567(7746):132. doi: 10.1038/s41586-019-0967-z.

40.

Normalizing Function of Tumor Vessels: Progress, Opportunities, and Challenges.

Martin JD, Seano G, Jain RK.

Annu Rev Physiol. 2019 Feb 10;81:505-534. doi: 10.1146/annurev-physiol-020518-114700.

41.

A Long-Term Study of Application of Joshi's External Stabilizing System in Displaced Intra-articular Distal End Radius Fractures.

Shukla R, Champawat VS, Jain RK.

J Wrist Surg. 2019 Feb;8(1):49-54. doi: 10.1055/s-0038-1668560. Epub 2018 Aug 19.

42.

Blocking CXCR4 alleviates desmoplasia, increases T-lymphocyte infiltration, and improves immunotherapy in metastatic breast cancer.

Chen IX, Chauhan VP, Posada J, Ng MR, Wu MW, Adstamongkonkul P, Huang P, Lindeman N, Langer R, Jain RK.

Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4558-4566. doi: 10.1073/pnas.1815515116. Epub 2019 Jan 30.

43.

Experimental and computational analyses reveal dynamics of tumor vessel cooption and optimal treatment strategies.

Voutouri C, Kirkpatrick ND, Chung E, Mpekris F, Baish JW, Munn LL, Fukumura D, Stylianopoulos T, Jain RK.

Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2662-2671. doi: 10.1073/pnas.1818322116. Epub 2019 Jan 30.

44.

Dual endothelin receptor inhibition enhances T-DM1 efficacy in brain metastases from HER2-positive breast cancer.

Askoxylakis V, Ferraro GB, Badeaux M, Kodack DP, Kirst I, Shankaraiah RC, Wong CSF, Duda DG, Fukumura D, Jain RK.

NPJ Breast Cancer. 2019 Jan 15;5:4. doi: 10.1038/s41523-018-0100-8. eCollection 2019.

45.

Taxonomy of the order Bunyavirales: second update 2018.

Maes P, Adkins S, Alkhovsky SV, Avšič-Županc T, Ballinger MJ, Bente DA, Beer M, Bergeron É, Blair CD, Briese T, Buchmeier MJ, Burt FJ, Calisher CH, Charrel RN, Choi IR, Clegg JCS, de la Torre JC, de Lamballerie X, DeRisi JL, Digiaro M, Drebot M, Ebihara H, Elbeaino T, Ergünay K, Fulhorst CF, Garrison AR, Gāo GF, Gonzalez JJ, Groschup MH, Günther S, Haenni AL, Hall RA, Hewson R, Hughes HR, Jain RK, Jonson MG, Junglen S, Klempa B, Klingström J, Kormelink R, Lambert AJ, Langevin SA, Lukashevich IS, Marklewitz M, Martelli GP, Mielke-Ehret N, Mirazimi A, Mühlbach HP, Naidu R, Nunes MRT, Palacios G, Papa A, Pawęska JT, Peters CJ, Plyusnin A, Radoshitzky SR, Resende RO, Romanowski V, Sall AA, Salvato MS, Sasaya T, Schmaljohn C, Shí X, Shirako Y, Simmonds P, Sironi M, Song JW, Spengler JR, Stenglein MD, Tesh RB, Turina M, Wèi T, Whitfield AE, Yeh SD, Zerbini FM, Zhang YZ, Zhou X, Kuhn JH.

Arch Virol. 2019 Mar;164(3):927-941. doi: 10.1007/s00705-018-04127-3.

46.

Losartan treatment enhances chemotherapy efficacy and reduces ascites in ovarian cancer models by normalizing the tumor stroma.

Zhao Y, Cao J, Melamed A, Worley M, Gockley A, Jones D, Nia HT, Zhang Y, Stylianopoulos T, Kumar AS, Mpekris F, Datta M, Sun Y, Wu L, Gao X, Yeku O, Del Carmen MG, Spriggs DR, Jain RK, Xu L.

Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):2210-2219. doi: 10.1073/pnas.1818357116. Epub 2019 Jan 18.

47.

Discovery of a ZIP7 inhibitor from a Notch pathway screen.

Nolin E, Gans S, Llamas L, Bandyopadhyay S, Brittain SM, Bernasconi-Elias P, Carter KP, Loureiro JJ, Thomas JR, Schirle M, Yang Y, Guo N, Roma G, Schuierer S, Beibel M, Lindeman A, Sigoillot F, Chen A, Xie KX, Ho S, Reece-Hoyes J, Weihofen WA, Tyskiewicz K, Hoepfner D, McDonald RI, Guthrie N, Dogra A, Guo H, Shao J, Ding J, Canham SM, Boynton G, George EL, Kang ZB, Antczak C, Porter JA, Wallace O, Tallarico JA, Palmer AE, Jenkins JL, Jain RK, Bushell SM, Fryer CJ.

Nat Chem Biol. 2019 Feb;15(2):179-188. doi: 10.1038/s41589-018-0200-7. Epub 2019 Jan 14.

PMID:
30643281
48.

Mapping Physical Tumor Microenvironment and Drug Delivery.

Nia HT, Munn LL, Jain RK.

Clin Cancer Res. 2019 Apr 1;25(7):2024-2026. doi: 10.1158/1078-0432.CCR-18-3724. Epub 2019 Jan 10.

49.

Clinical Outcomes of Novel Long-Tapered Sirolimus-Eluting Coronary Stent System in Real-World Patients With Long Diffused De Novo Coronary Lesions.

Patted SV, Jain RK, Jiwani PA, Suryavanshi S, Raghu TR, Raveesh H, Rajalakshmi S, Thakkar AS, Turiya PK, Desai PJ, Patted AS, Sharma KH.

Cardiol Res. 2018 Dec;9(6):350-357. doi: 10.14740/cr795. Epub 2018 Dec 7.

50.

A cerebellopontine angle mouse model for the investigation of tumor biology, hearing, and neurological function in NF2-related vestibular schwannoma.

Chen J, Landegger LD, Sun Y, Ren J, Maimon N, Wu L, Ng MR, Chen JW, Zhang N, Zhao Y, Gao X, Fujita T, Roberge S, Huang P, Jain RK, Plotkin SR, Stankovic KM, Xu L.

Nat Protoc. 2019 Feb;14(2):541-555. doi: 10.1038/s41596-018-0105-7.

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