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Items: 1 to 50 of 1167

1.

Vessel co-option in glioblastoma: emerging insights and opportunities.

Seano G, Jain RK.

Angiogenesis. 2019 Nov 2. doi: 10.1007/s10456-019-09691-z. [Epub ahead of print] Review.

PMID:
31679081
2.

The blood-brain barrier and blood-tumour barrier in brain tumours and metastases.

Arvanitis CD, Ferraro GB, Jain RK.

Nat Rev Cancer. 2019 Oct 10. doi: 10.1038/s41568-019-0205-x. [Epub ahead of print] Review.

PMID:
31601988
3.

Bevacizumab reduces permeability and concurrent temozolomide delivery in a subset of patients with recurrent glioblastoma.

Gerstner E, Emblem KE, Chang K, Vakulenko-Lagun B, Yen YF, Beers AL, Dietrich J, Plotkin SR, Catana C, Hooker JM, Duda DG, Rosen B, Kalpathy-Cramer J, Jain RK, Batchelor T.

Clin Cancer Res. 2019 Sep 26. pii: clincanres.1739.2019. doi: 10.1158/1078-0432.CCR-19-1739. [Epub ahead of print]

PMID:
31558474
4.

A phase II study of cabozantinib alone or in combination with trastuzumab in breast cancer patients with brain metastases.

Leone JP, Duda DG, Hu J, Barry WT, Trippa L, Gerstner ER, Jain RK, Tan S, Lawler E, Winer EP, Lin NU, Tolaney SM.

Breast Cancer Res Treat. 2019 Sep 20. doi: 10.1007/s10549-019-05445-z. [Epub ahead of print]

PMID:
31541381
5.

Effect of Aflibercept Plus Modified FOLFOX6 Induction Chemotherapy Before Standard Chemoradiotherapy and Surgery in Patients With High-Risk Rectal Adenocarcinoma: The GEMCAD 1402 Randomized Clinical Trial.

Fernández-Martos C, Pericay C, Losa F, García-Carbonero R, Layos L, Rodríguez-Salas N, Martin-Richard M, Alonso-Orduña V, Vera R, Gallego J, Capdevila J, Salud A, Nogué M, Maurel J, Guash I, Montagut C, Lopez C, Macias I, Jain RK, Garcia-Albeniz X.

JAMA Oncol. 2019 Aug 29. doi: 10.1001/jamaoncol.2019.2294. [Epub ahead of print]

PMID:
31465088
6.

Non-invasive diagnosis and monitoring of urothelial bladder cancer: are we there yet?

Jain RK, Grivas P, Pal SK.

BJU Int. 2019 Sep;124(3):361-362. doi: 10.1111/bju.14877. No abstract available.

PMID:
31436040
7.

Clinical Development of PARP Inhibitors in Treating Metastatic Castration-Resistant Prostate Cancer.

Adashek JJ, Jain RK, Zhang J.

Cells. 2019 Aug 9;8(8). pii: E860. doi: 10.3390/cells8080860. Review.

8.

Vascular regulation of antitumor immunity.

Munn LL, Jain RK.

Science. 2019 Aug 9;365(6453):544-545. doi: 10.1126/science.aaw7875. No abstract available.

PMID:
31395771
9.

Dual Programmed Death Receptor-1 and Vascular Endothelial Growth Factor Receptor-2 Blockade Promotes Vascular Normalization and Enhances Antitumor Immune Responses in Hepatocellular Carcinoma.

Shigeta K, Datta M, Hato T, Kitahara S, Chen IX, Matsui A, Kikuchi H, Mamessier E, Aoki S, Ramjiawan RR, Ochiai H, Bardeesy N, Huang P, Cobbold M, Zhu AX, Jain RK, Duda DG.

Hepatology. 2019 Aug 5. doi: 10.1002/hep.30889. [Epub ahead of print]

PMID:
31378984
10.

Diabetes-Related Fracture Risk Is Different in African Americans Compared With Hispanics and Caucasians.

Jain RK, Weiner MG, Zhao H, Williams KJ, Vokes T.

J Clin Endocrinol Metab. 2019 Nov 1;104(11):5729-5736. doi: 10.1210/jc.2019-00931.

PMID:
31369094
11.

A study of attributable variables impacting orthopedic trauma surgical training.

Shukla R, Champawat VS, Jain RK.

Chin J Traumatol. 2019 Oct;22(5):278-280. doi: 10.1016/j.cjtee.2019.05.001. Epub 2019 Jun 20.

12.

Publisher Correction: Probing tumor microenvironment in patients with newly diagnosed glioblastoma during chemoradiation and adjuvant temozolomide with functional MRI.

Ly KI, Vakulenko-Lagun B, Emblem KE, Ou Y, Da X, Betensky RA, Kalpathy-Cramer J, Duda DG, Jain RK, Chi AS, Plotkin SR, Batchelor TT, Sorensen G, Rosen BR, Gerstner ER.

Sci Rep. 2019 Jun 14;9(1):8721. doi: 10.1038/s41598-019-44365-2.

13.

Total Neoadjuvant Therapy With FOLFIRINOX in Combination With Losartan Followed by Chemoradiotherapy for Locally Advanced Pancreatic Cancer: A Phase 2 Clinical Trial.

Murphy JE, Wo JY, Ryan DP, Clark JW, Jiang W, Yeap BY, Drapek LC, Ly L, Baglini CV, Blaszkowsky LS, Ferrone CR, Parikh AR, Weekes CD, Nipp RD, Kwak EL, Allen JN, Corcoran RB, Ting DT, Faris JE, Zhu AX, Goyal L, Berger DL, Qadan M, Lillemoe KD, Talele N, Jain RK, DeLaney TF, Duda DG, Boucher Y, Fernández-Del Castillo C, Hong TS.

JAMA Oncol. 2019 Jul 1;5(7):1020-1027. doi: 10.1001/jamaoncol.2019.0892.

PMID:
31145418
14.

Correction to: Immunotherapy Advances in Urothelial Carcinoma.

Jain RK, Snyders T, Nandagopal L, Garje R, Zakharia Y, Gupta S.

Curr Treat Options Oncol. 2019 May 23;20(7):53. doi: 10.1007/s11864-019-0660-3.

PMID:
31119396
15.

De novo genome sequencing and secretome analysis of Tilletia indica inciting Karnal bunt of wheat provides pathogenesis-related genes.

Gurjar MS, Aggarwal R, Jogawat A, Kulshreshtha D, Sharma S, Solanke AU, Dubey H, Jain RK.

3 Biotech. 2019 Jun;9(6):219. doi: 10.1007/s13205-019-1743-3. Epub 2019 May 20.

PMID:
31114743
16.

Reprogramming the Tumor Microenvironment to Improve Immunotherapy: Emerging Strategies and Combination Therapies.

Datta M, Coussens LM, Nishikawa H, Hodi FS, Jain RK.

Am Soc Clin Oncol Educ Book. 2019 Jan;39:165-174. doi: 10.1200/EDBK_237987. Epub 2019 May 17. Review.

PMID:
31099649
17.

First Draft Genome Sequence of a Pearl Millet Blast Pathogen, Magnaporthe grisea Strain PMg_Dl, Obtained Using PacBio Single-Molecule Real-Time and Illumina NextSeq 500 Sequencing.

Prakash G, Kumar A, Sheoran N, Aggarwal R, Satyavathi CT, Chikara SK, Ghosh A, Jain RK.

Microbiol Resour Announc. 2019 May 16;8(20). pii: e01499-18. doi: 10.1128/MRA.01499-18.

18.

Danger zone of radial nerve in Indian population - A cadaveric study.

Jain RK, Champawat VS, Mandlecha P.

J Clin Orthop Trauma. 2019 May-Jun;10(3):531-534. doi: 10.1016/j.jcot.2018.02.006. Epub 2018 Feb 21.

PMID:
31061584
19.

Role of Apelin in Glioblastoma Vascularization and Invasion after Anti-VEGF Therapy: What Is the Impact on the Immune System?

Amoozgar Z, Jain RK, Duda DG.

Cancer Res. 2019 May 1;79(9):2104-2106. doi: 10.1158/0008-5472.CAN-19-0749.

20.

Reprogramming the microenvironment with tumor-selective angiotensin blockers enhances cancer immunotherapy.

Chauhan VP, Chen IX, Tong R, Ng MR, Martin JD, Naxerova K, Wu MW, Huang P, Boucher Y, Kohane DS, Langer R, Jain RK.

Proc Natl Acad Sci U S A. 2019 May 28;116(22):10674-10680. doi: 10.1073/pnas.1819889116. Epub 2019 Apr 30.

21.

Important caveats of KEYNOTE-045: relevance of these findings in the current and future therapeutic paradigm.

Slongo J, Jain RK, Spiess PE.

Ann Transl Med. 2019 Mar;7(Suppl 1):S23. doi: 10.21037/atm.2019.01.81. No abstract available.

22.

Pharyngeal-Cervical-Brachial Variant of Guillain-Barré Syndrome Following Dengue Infection: A Rare Syndrome with Rare Association.

Pandey RK, Jain RK, Hussain SZ.

Ann Indian Acad Neurol. 2019 Apr-Jun;22(2):240-241. doi: 10.4103/aian.AIAN_253_18.

23.

Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium.

Seano G, Nia HT, Emblem KE, Datta M, Ren J, Krishnan S, Kloepper J, Pinho MC, Ho WW, Ghosh M, Askoxylakis V, Ferraro GB, Riedemann L, Gerstner ER, Batchelor TT, Wen PY, Lin NU, Grodzinsky AJ, Fukumura D, Huang P, Baish JW, Padera TP, Munn LL, Jain RK.

Nat Biomed Eng. 2019 Mar;3(3):230-245. doi: 10.1038/s41551-018-0334-7. Epub 2019 Jan 7.

24.

FOLFOX plus ziv-aflibercept or placebo in first-line metastatic esophagogastric adenocarcinoma: A double-blind, randomized, multicenter phase 2 trial.

Cleary JM, Horick NK, McCleary NJ, Abrams TA, Yurgelun MB, Azzoli CG, Rubinson DA, Brooks GA, Chan JA, Blaszkowsky LS, Clark JW, Goyal L, Meyerhardt JA, Ng K, Schrag D, Savarese DMF, Graham C, Fitzpatrick B, Gibb KA, Boucher Y, Duda DG, Jain RK, Fuchs CS, Enzinger PC.

Cancer. 2019 Mar 26. doi: 10.1002/cncr.32029. [Epub ahead of print]

PMID:
30913304
25.
26.

Retraction Note: A homing system targets therapeutic T cells to brain cancer.

Samaha H, Pignata A, Fousek K, Ren J, Lam FW, Stossi F, Dubrulle J, Salsman VS, Krishnan S, Hong SH, Baker ML, Shree A, Gad AZ, Shum T, Fukumura D, Byrd TT, Mukherjee M, Marrelli SP, Orange JS, Joseph SK, Sorensen PH, Taylor MD, Hegde M, Mamonkin M, Jain RK, El-Naggar S, Ahmed N.

Nature. 2019 Mar;567(7746):132. doi: 10.1038/s41586-019-0967-z.

27.

Normalizing Function of Tumor Vessels: Progress, Opportunities, and Challenges.

Martin JD, Seano G, Jain RK.

Annu Rev Physiol. 2019 Feb 10;81:505-534. doi: 10.1146/annurev-physiol-020518-114700.

28.

A Long-Term Study of Application of Joshi's External Stabilizing System in Displaced Intra-articular Distal End Radius Fractures.

Shukla R, Champawat VS, Jain RK.

J Wrist Surg. 2019 Feb;8(1):49-54. doi: 10.1055/s-0038-1668560. Epub 2018 Aug 19.

PMID:
30723602
29.

Blocking CXCR4 alleviates desmoplasia, increases T-lymphocyte infiltration, and improves immunotherapy in metastatic breast cancer.

Chen IX, Chauhan VP, Posada J, Ng MR, Wu MW, Adstamongkonkul P, Huang P, Lindeman N, Langer R, Jain RK.

Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4558-4566. doi: 10.1073/pnas.1815515116. Epub 2019 Jan 30.

30.

Experimental and computational analyses reveal dynamics of tumor vessel cooption and optimal treatment strategies.

Voutouri C, Kirkpatrick ND, Chung E, Mpekris F, Baish JW, Munn LL, Fukumura D, Stylianopoulos T, Jain RK.

Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2662-2671. doi: 10.1073/pnas.1818322116. Epub 2019 Jan 30.

31.

Dual endothelin receptor inhibition enhances T-DM1 efficacy in brain metastases from HER2-positive breast cancer.

Askoxylakis V, Ferraro GB, Badeaux M, Kodack DP, Kirst I, Shankaraiah RC, Wong CSF, Duda DG, Fukumura D, Jain RK.

NPJ Breast Cancer. 2019 Jan 15;5:4. doi: 10.1038/s41523-018-0100-8. eCollection 2019.

32.

Taxonomy of the order Bunyavirales: second update 2018.

Maes P, Adkins S, Alkhovsky SV, Avšič-Županc T, Ballinger MJ, Bente DA, Beer M, Bergeron É, Blair CD, Briese T, Buchmeier MJ, Burt FJ, Calisher CH, Charrel RN, Choi IR, Clegg JCS, de la Torre JC, de Lamballerie X, DeRisi JL, Digiaro M, Drebot M, Ebihara H, Elbeaino T, Ergünay K, Fulhorst CF, Garrison AR, Gāo GF, Gonzalez JJ, Groschup MH, Günther S, Haenni AL, Hall RA, Hewson R, Hughes HR, Jain RK, Jonson MG, Junglen S, Klempa B, Klingström J, Kormelink R, Lambert AJ, Langevin SA, Lukashevich IS, Marklewitz M, Martelli GP, Mielke-Ehret N, Mirazimi A, Mühlbach HP, Naidu R, Nunes MRT, Palacios G, Papa A, Pawęska JT, Peters CJ, Plyusnin A, Radoshitzky SR, Resende RO, Romanowski V, Sall AA, Salvato MS, Sasaya T, Schmaljohn C, Shí X, Shirako Y, Simmonds P, Sironi M, Song JW, Spengler JR, Stenglein MD, Tesh RB, Turina M, Wèi T, Whitfield AE, Yeh SD, Zerbini FM, Zhang YZ, Zhou X, Kuhn JH.

Arch Virol. 2019 Mar;164(3):927-941. doi: 10.1007/s00705-018-04127-3.

PMID:
30663021
33.

Losartan treatment enhances chemotherapy efficacy and reduces ascites in ovarian cancer models by normalizing the tumor stroma.

Zhao Y, Cao J, Melamed A, Worley M, Gockley A, Jones D, Nia HT, Zhang Y, Stylianopoulos T, Kumar AS, Mpekris F, Datta M, Sun Y, Wu L, Gao X, Yeku O, Del Carmen MG, Spriggs DR, Jain RK, Xu L.

Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):2210-2219. doi: 10.1073/pnas.1818357116. Epub 2019 Jan 18.

34.

Discovery of a ZIP7 inhibitor from a Notch pathway screen.

Nolin E, Gans S, Llamas L, Bandyopadhyay S, Brittain SM, Bernasconi-Elias P, Carter KP, Loureiro JJ, Thomas JR, Schirle M, Yang Y, Guo N, Roma G, Schuierer S, Beibel M, Lindeman A, Sigoillot F, Chen A, Xie KX, Ho S, Reece-Hoyes J, Weihofen WA, Tyskiewicz K, Hoepfner D, McDonald RI, Guthrie N, Dogra A, Guo H, Shao J, Ding J, Canham SM, Boynton G, George EL, Kang ZB, Antczak C, Porter JA, Wallace O, Tallarico JA, Palmer AE, Jenkins JL, Jain RK, Bushell SM, Fryer CJ.

Nat Chem Biol. 2019 Feb;15(2):179-188. doi: 10.1038/s41589-018-0200-7. Epub 2019 Jan 14.

PMID:
30643281
35.

Mapping Physical Tumor Microenvironment and Drug Delivery.

Nia HT, Munn LL, Jain RK.

Clin Cancer Res. 2019 Apr 1;25(7):2024-2026. doi: 10.1158/1078-0432.CCR-18-3724. Epub 2019 Jan 10.

PMID:
30630829
36.

Clinical Outcomes of Novel Long-Tapered Sirolimus-Eluting Coronary Stent System in Real-World Patients With Long Diffused De Novo Coronary Lesions.

Patted SV, Jain RK, Jiwani PA, Suryavanshi S, Raghu TR, Raveesh H, Rajalakshmi S, Thakkar AS, Turiya PK, Desai PJ, Patted AS, Sharma KH.

Cardiol Res. 2018 Dec;9(6):350-357. doi: 10.14740/cr795. Epub 2018 Dec 7.

37.

A cerebellopontine angle mouse model for the investigation of tumor biology, hearing, and neurological function in NF2-related vestibular schwannoma.

Chen J, Landegger LD, Sun Y, Ren J, Maimon N, Wu L, Ng MR, Chen JW, Zhang N, Zhao Y, Gao X, Fujita T, Roberge S, Huang P, Jain RK, Plotkin SR, Stankovic KM, Xu L.

Nat Protoc. 2019 Feb;14(2):541-555. doi: 10.1038/s41596-018-0105-7.

38.

Development of Soybean Yellow Mottle Mosaic Virus-Based Expression Vector for Heterologous Protein Expression in French Bean.

Sandra N, Jailani AAK, Jain RK, Mandal B.

Mol Biotechnol. 2019 Mar;61(3):181-190. doi: 10.1007/s12033-018-0147-7.

PMID:
30600448
39.

Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models.

Keklikoglou I, Cianciaruso C, Güç E, Squadrito ML, Spring LM, Tazzyman S, Lambein L, Poissonnier A, Ferraro GB, Baer C, Cassará A, Guichard A, Iruela-Arispe ML, Lewis CE, Coussens LM, Bardia A, Jain RK, Pollard JW, De Palma M.

Nat Cell Biol. 2019 Feb;21(2):190-202. doi: 10.1038/s41556-018-0256-3. Epub 2018 Dec 31.

40.

Immunotherapy Advances in Urothelial Carcinoma.

Jain RK, Snyders T, Nandgoapal L, Garje R, Zakharia Y, Gupta S.

Curr Treat Options Oncol. 2018 Dec 15;19(12):79. doi: 10.1007/s11864-018-0598-x. Review. Erratum in: Curr Treat Options Oncol. 2019 May 23;20(7):53.

PMID:
30554335
41.

Potential of in situ SSF laccase produced from Ganoderma lucidum RCK 2011 in biobleaching of paper pulp.

Sharma A, Jain KK, Srivastava A, Shrivastava B, Thakur VV, Jain RK, Kuhad RC.

Bioprocess Biosyst Eng. 2019 Mar;42(3):367-377. doi: 10.1007/s00449-018-2041-x. Epub 2018 Nov 23.

PMID:
30470907
42.

Previously Uncharacterized Vacuolar-type ATPase Binding Site Discovered from Structurally Similar Compounds with Distinct Mechanisms of Action.

Wang AC, Pham HT, Lipps JM, Brittain SM, Harrington E, Wang Y, King FJ, Russ C, Pan X, Hoepfner D, Tallarico J, Feng Y, Jain RK, Schirle M, Thomas JR.

ACS Chem Biol. 2019 Jan 18;14(1):20-26. doi: 10.1021/acschembio.8b00656. Epub 2018 Dec 18.

PMID:
30461263
43.

Probing tumor microenvironment in patients with newly diagnosed glioblastoma during chemoradiation and adjuvant temozolomide with functional MRI.

Ly KI, Vakulenko-Lagun B, Emblem KE, Ou Y, Da X, Betensky RA, Kalpathy-Cramer J, Duda DG, Jain RK, Chi AS, Plotkin SR, Batchelor TT, Sorensen G, Rosen BR, Gerstner ER.

Sci Rep. 2018 Nov 20;8(1):17062. doi: 10.1038/s41598-018-34820-x. Erratum in: Sci Rep. 2019 Jun 14;9(1):8721.

44.

Inducible Nitric Oxide Synthase and CD11b+Gr1+ Cells Impair Lymphatic Contraction of Tumor-Draining Lymphatic Vessels.

Liao S, Bouta EM, Morris LM, Jones D, Jain RK, Padera TP.

Lymphat Res Biol. 2019 Jun;17(3):294-300. doi: 10.1089/lrb.2018.0013. Epub 2018 Oct 24.

PMID:
30358484
45.

Publisher Correction: Engineering and physical sciences in oncology: challenges and opportunities.

Mitchell MJ, Jain RK, Langer R.

Nat Rev Cancer. 2018 Nov;18(11):720. doi: 10.1038/s41568-018-0072-x.

46.

Cochlear Proteins Associated with Noise-induced Hearing Loss: An Update.

Jain RK, Pingle SK, Tumane RG, Thakkar LR, Jawade AA, Barapatre A, Trivedi M.

Indian J Occup Environ Med. 2018 May-Aug;22(2):60-73. doi: 10.4103/ijoem.IJOEM_43_18. Review.

47.

A Phase II and Biomarker Study of Sorafenib Combined with Modified FOLFOX in Patients with Advanced Hepatocellular Carcinoma.

Goyal L, Zheng H, Abrams TA, Miksad R, Bullock AJ, Allen JN, Yurgelun MB, Clark JW, Kambadakone A, Muzikansky A, Knowles M, Galway A, Afflitto AJ, Dinicola CF, Regan E, Hato T, Mamessier E, Shigeta K, Jain RK, Duda DG, Zhu AX.

Clin Cancer Res. 2019 Jan 1;25(1):80-89. doi: 10.1158/1078-0432.CCR-18-0847. Epub 2018 Sep 6.

48.

A homing system targets therapeutic T cells to brain cancer.

Samaha H, Pignata A, Fousek K, Ren J, Lam FW, Stossi F, Dubrulle J, Salsman VS, Krishnan S, Hong SH, Baker ML, Shree A, Gad AZ, Shum T, Fukumura D, Byrd TT, Mukherjee M, Marrelli SP, Orange JS, Joseph SK, Sorensen PH, Taylor MD, Hegde M, Mamonkin M, Jain RK, El-Naggar S, Ahmed N.

Nature. 2018 Sep;561(7723):331-337. doi: 10.1038/s41586-018-0499-y. Epub 2018 Sep 5. Retraction in: Nature. 2019 Mar;567(7746):132.

49.

Mechanisms of enhanced drug delivery in brain metastases with focused ultrasound-induced blood-tumor barrier disruption.

Arvanitis CD, Askoxylakis V, Guo Y, Datta M, Kloepper J, Ferraro GB, Bernabeu MO, Fukumura D, McDannold N, Jain RK.

Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):E8717-E8726. doi: 10.1073/pnas.1807105115. Epub 2018 Aug 27.

50.

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