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Items: 1 to 50 of 422

1.

Spatial patterns of tau deposition are associated with amyloid, ApoE, sex, and cognitive decline in older adults.

Pereira JB, Harrison TM, La Joie R, Baker SL, Jagust WJ.

Eur J Nucl Med Mol Imaging. 2020 Jan 8. doi: 10.1007/s00259-019-04669-x. [Epub ahead of print]

PMID:
31915896
2.

Prospective longitudinal atrophy in Alzheimer's disease correlates with the intensity and topography of baseline tau-PET.

La Joie R, Visani AV, Baker SL, Brown JA, Bourakova V, Cha J, Chaudhary K, Edwards L, Iaccarino L, Janabi M, Lesman-Segev OH, Miller ZA, Perry DC, O'Neil JP, Pham J, Rojas JC, Rosen HJ, Seeley WW, Tsai RM, Miller BL, Jagust WJ, Rabinovici GD.

Sci Transl Med. 2020 Jan 1;12(524). pii: eaau5732. doi: 10.1126/scitranslmed.aau5732.

PMID:
31894103
3.

What are the threats to successful brain and cognitive aging?

Gallagher M, Okonkwo OC, Resnick SM, Jagust WJ, Benzinger TLS, Rapp PR.

Neurobiol Aging. 2019 Nov;83:130-134. doi: 10.1016/j.neurobiolaging.2019.04.016.

PMID:
31732016
4.

Tau PET and multimodal brain imaging in patients at risk for chronic traumatic encephalopathy.

Lesman-Segev OH, La Joie R, Stephens ML, Sonni I, Tsai R, Bourakova V, Visani AV, Edwards L, O'Neil JP, Baker SL, Gardner RC, Janabi M, Chaudhary K, Perry DC, Kramer JH, Miller BL, Jagust WJ, Rabinovici GD.

Neuroimage Clin. 2019;24:102025. doi: 10.1016/j.nicl.2019.102025. Epub 2019 Oct 17.

5.

Tau deposition is associated with functional isolation of the hippocampus in aging.

Harrison TM, Maass A, Adams JN, Du R, Baker SL, Jagust WJ.

Nat Commun. 2019 Oct 25;10(1):4900. doi: 10.1038/s41467-019-12921-z.

6.

Cortical tau deposition follows patterns of entorhinal functional connectivity in aging.

Adams JN, Maass A, Harrison TM, Baker SL, Jagust WJ.

Elife. 2019 Sep 2;8. pii: e49132. doi: 10.7554/eLife.49132.

7.

Sleep as a Potential Biomarker of Tau and β-Amyloid Burden in the Human Brain.

Winer JR, Mander BA, Helfrich RF, Maass A, Harrison TM, Baker SL, Knight RT, Jagust WJ, Walker MP.

J Neurosci. 2019 Aug 7;39(32):6315-6324. doi: 10.1523/JNEUROSCI.0503-19.2019. Epub 2019 Jun 17.

8.

Development of a mnemonic discrimination task using naturalistic stimuli with applications to aging and preclinical Alzheimer's disease.

Leal SL, Ferguson LA, Harrison TM, Jagust WJ.

Learn Mem. 2019 Jun 17;26(7):219-228. doi: 10.1101/lm.048967.118. Print 2019 Jul.

PMID:
31209116
9.

Alzheimer's pathology targets distinct memory networks in the ageing brain.

Maass A, Berron D, Harrison TM, Adams JN, La Joie R, Baker S, Mellinger T, Bell RK, Swinnerton K, Inglis B, Rabinovici GD, Düzel E, Jagust WJ.

Brain. 2019 Aug 1;142(8):2492-2509. doi: 10.1093/brain/awz154.

PMID:
31199481
10.

Tau covariance patterns in Alzheimer's disease patients match intrinsic connectivity networks in the healthy brain.

Ossenkoppele R, Iaccarino L, Schonhaut DR, Brown JA, La Joie R, O'Neil JP, Janabi M, Baker SL, Kramer JH, Gorno-Tempini ML, Miller BL, Rosen HJ, Seeley WW, Jagust WJ, Rabinovici GD.

Neuroimage Clin. 2019;23:101848. doi: 10.1016/j.nicl.2019.101848. Epub 2019 May 2.

11.

Effect of Off-Target Binding on 18F-Flortaucipir Variability in Healthy Controls Across the Life Span.

Baker SL, Harrison TM, Maass A, La Joie R, Jagust WJ.

J Nucl Med. 2019 Oct;60(10):1444-1451. doi: 10.2967/jnumed.118.224113. Epub 2019 Mar 15.

PMID:
30877180
12.

Vascular Burden Score Impacts Cognition Independent of Amyloid PET and MRI Measures of Alzheimer's Disease and Vascular Brain Injury.

DeCarli C, Villeneuve S, Maillard P, Harvey D, Singh B, Carmichael O, Fletcher E, Olichney J, Farias S, Jagust W, Reed B, Mungas D.

J Alzheimers Dis. 2019;68(1):187-196. doi: 10.3233/JAD-180965.

13.

Dopaminergic Mechanisms Underlying Normal Variation in Trait Anxiety.

Berry AS, White RL 3rd, Furman DJ, Naskolnakorn JR, Shah VD, D'Esposito M, Jagust WJ.

J Neurosci. 2019 Apr 3;39(14):2735-2744. doi: 10.1523/JNEUROSCI.2382-18.2019. Epub 2019 Feb 8.

14.

18F-flortaucipir (AV-1451) tau PET in frontotemporal dementia syndromes.

Tsai RM, Bejanin A, Lesman-Segev O, LaJoie R, Visani A, Bourakova V, O'Neil JP, Janabi M, Baker S, Lee SE, Perry DC, Bajorek L, Karydas A, Spina S, Grinberg LT, Seeley WW, Ramos EM, Coppola G, Gorno-Tempini ML, Miller BL, Rosen HJ, Jagust W, Boxer AL, Rabinovici GD.

Alzheimers Res Ther. 2019 Jan 31;11(1):13. doi: 10.1186/s13195-019-0470-7.

15.

"Alzheimer's disease" is neither "Alzheimer's clinical syndrome" nor "dementia".

Jagust W, Jack CR Jr, Bennett DA, Blennow K, Haeberlein SB, Holtzman DM, Jessen F, Karlawish J, Liu E, Molinuevo JL, Montine T, Phelps C, Rankin KP, Rowe CC, Scheltens P, Siemers E, Sperling R.

Alzheimers Dement. 2019 Jan;15(1):153-157. doi: 10.1016/j.jalz.2018.11.002. No abstract available.

PMID:
30642435
16.

Longitudinal tau accumulation and atrophy in aging and alzheimer disease.

Harrison TM, La Joie R, Maass A, Baker SL, Swinnerton K, Fenton L, Mellinger TJ, Edwards L, Pham J, Miller BL, Rabinovici GD, Jagust WJ.

Ann Neurol. 2019 Feb;85(2):229-240. doi: 10.1002/ana.25406. Epub 2019 Jan 17.

17.

Age-related variability in decision-making: Insights from neurochemistry.

Berry AS, Jagust WJ, Hsu M.

Cogn Affect Behav Neurosci. 2019 Jun;19(3):415-434. doi: 10.3758/s13415-018-00678-9.

18.

Biomarkers for tau pathology.

Schöll M, Maass A, Mattsson N, Ashton NJ, Blennow K, Zetterberg H, Jagust W.

Mol Cell Neurosci. 2019 Jun;97:18-33. doi: 10.1016/j.mcn.2018.12.001. Epub 2018 Dec 7. Review.

19.

Multisite study of the relationships between antemortem [11C]PIB-PET Centiloid values and postmortem measures of Alzheimer's disease neuropathology.

La Joie R, Ayakta N, Seeley WW, Borys E, Boxer AL, DeCarli C, Doré V, Grinberg LT, Huang E, Hwang JH, Ikonomovic MD, Jack C Jr, Jagust WJ, Jin LW, Klunk WE, Kofler J, Lesman-Segev OH, Lockhart SN, Lowe VJ, Masters CL, Mathis CA, McLean CL, Miller BL, Mungas D, O'Neil JP, Olichney JM, Parisi JE, Petersen RC, Rosen HJ, Rowe CC, Spina S, Vemuri P, Villemagne VL, Murray ME, Rabinovici GD.

Alzheimers Dement. 2019 Feb;15(2):205-216. doi: 10.1016/j.jalz.2018.09.001. Epub 2018 Oct 19.

20.

Understanding disease progression and improving Alzheimer's disease clinical trials: Recent highlights from the Alzheimer's Disease Neuroimaging Initiative.

Veitch DP, Weiner MW, Aisen PS, Beckett LA, Cairns NJ, Green RC, Harvey D, Jack CR Jr, Jagust W, Morris JC, Petersen RC, Saykin AJ, Shaw LM, Toga AW, Trojanowski JQ; Alzheimer's Disease Neuroimaging Initiative.

Alzheimers Dement. 2019 Jan;15(1):106-152. doi: 10.1016/j.jalz.2018.08.005. Epub 2018 Oct 13. Review.

PMID:
30321505
21.

Imaging the evolution and pathophysiology of Alzheimer disease.

Jagust W.

Nat Rev Neurosci. 2018 Nov;19(11):687-700. doi: 10.1038/s41583-018-0067-3. Review.

PMID:
30266970
22.

Scan-Time Corrections for 80-100-min Standardizetd Uptake Volume Ratios to Measure the 18F-AV-1451 Tracer for Tau Imaging.

He M, Baker SL, Shah VD, Lockhart SN, Jagust WJ.

IEEE Trans Med Imaging. 2019 Mar;38(3):697-709. doi: 10.1109/TMI.2018.2870441. Epub 2018 Sep 17.

PMID:
30235119
23.

Spatially Adaptive Varying Correlation Analysis for Multimodal Neuroimaging Data.

Li L, Kang J, Lockhart SN, Adams J, Jagust WJ.

IEEE Trans Med Imaging. 2019 Jan;38(1):113-123. doi: 10.1109/TMI.2018.2857221. Epub 2018 Jul 18.

24.

A New Tool for Clinical Neuroscience-Synaptic Imaging.

Mormino EC, Jagust WJ.

JAMA Neurol. 2018 Oct 1;75(10):1181-1183. doi: 10.1001/jamaneurol.2018.1643. No abstract available.

PMID:
30014142
25.

Relationships Between Tau and Glucose Metabolism Reflect Alzheimer's Disease Pathology in Cognitively Normal Older Adults.

Adams JN, Lockhart SN, Li L, Jagust WJ.

Cereb Cortex. 2019 May 1;29(5):1997-2009. doi: 10.1093/cercor/bhy078.

PMID:
29912295
26.

Assessment of Extent and Role of Tau in Subcortical Vascular Cognitive Impairment Using 18F-AV1451 Positron Emission Tomography Imaging.

Kim HJ, Park S, Cho H, Jang YK, San Lee J, Jang H, Kim Y, Kim KW, Ryu YH, Choi JY, Moon SH, Weiner MW, Jagust WJ, Rabinovici GD, DeCarli C, Lyoo CH, Na DL, Seo SW.

JAMA Neurol. 2018 Aug 1;75(8):999-1007. doi: 10.1001/jamaneurol.2018.0975.

27.

The Influence of Dopamine on Cognitive Flexibility Is Mediated by Functional Connectivity in Young but Not Older Adults.

Berry AS, Shah VD, Jagust WJ.

J Cogn Neurosci. 2018 Sep;30(9):1330-1344. doi: 10.1162/jocn_a_01286. Epub 2018 May 23.

28.

Subthreshold Amyloid Predicts Tau Deposition in Aging.

Leal SL, Lockhart SN, Maass A, Bell RK, Jagust WJ.

J Neurosci. 2018 May 9;38(19):4482-4489. doi: 10.1523/JNEUROSCI.0485-18.2018. Epub 2018 Apr 23.

29.

Brain morphology, cognition, and β-amyloid in older adults with superior memory performance.

Harrison TM, Maass A, Baker SL, Jagust WJ.

Neurobiol Aging. 2018 Jul;67:162-170. doi: 10.1016/j.neurobiolaging.2018.03.024. Epub 2018 Mar 27.

30.

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease.

Jack CR Jr, Bennett DA, Blennow K, Carrillo MC, Dunn B, Haeberlein SB, Holtzman DM, Jagust W, Jessen F, Karlawish J, Liu E, Molinuevo JL, Montine T, Phelps C, Rankin KP, Rowe CC, Scheltens P, Siemers E, Snyder HM, Sperling R; Contributors.

Alzheimers Dement. 2018 Apr;14(4):535-562. doi: 10.1016/j.jalz.2018.02.018. Review.

31.

Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease.

Mattsson N, Groot C, Jansen WJ, Landau SM, Villemagne VL, Engelborghs S, Mintun MM, Lleo A, Molinuevo JL, Jagust WJ, Frisoni GB, Ivanoiu A, Chételat G, Resende de Oliveira C, Rodrigue KM, Kornhuber J, Wallin A, Klimkowicz-Mrowiec A, Kandimalla R, Popp J, Aalten PP, Aarsland D, Alcolea D, Almdahl IS, Baldeiras I, van Buchem MA, Cavedo E, Chen K, Cohen AD, Förster S, Fortea J, Frederiksen KS, Freund-Levi Y, Gill KD, Gkatzima O, Grimmer T, Hampel H, Herukka SK, Johannsen P, van Laere K, de Leon MJ, Maier W, Marcusson J, Meulenbroek O, Møllergård HM, Morris JC, Mroczko B, Nordlund A, Prabhakar S, Peters O, Rami L, Rodríguez-Rodríguez E, Roe CM, Rüther E, Santana I, Schröder J, Seo SW, Soininen H, Spiru L, Stomrud E, Struyfs H, Teunissen CE, Verhey FRJ, Vos SJB, van Waalwijk van Doorn LJC, Waldemar G, Wallin ÅK, Wiltfang J, Vandenberghe R, Brooks DJ, Fladby T, Rowe CC, Drzezga A, Verbeek MM, Sarazin M, Wolk DA, Fleisher AS, Klunk WE, Na DL, Sánchez-Juan P, Lee DY, Nordberg A, Tsolaki M, Camus V, Rinne JO, Fagan AM, Zetterberg H, Blennow K, Rabinovici GD, Hansson O, van Berckel BNM, van der Flier WM, Scheltens P, Visser PJ, Ossenkoppele R.

Alzheimers Dement. 2018 Jul;14(7):913-924. doi: 10.1016/j.jalz.2018.02.009. Epub 2018 Mar 28.

PMID:
29601787
32.

Memory decline accompanies subthreshold amyloid accumulation.

Landau SM, Horng A, Jagust WJ; Alzheimer's Disease Neuroimaging Initiative.

Neurology. 2018 Apr 24;90(17):e1452-e1460. doi: 10.1212/WNL.0000000000005354. Epub 2018 Mar 23.

33.

Metabolic brain networks in aging and preclinical Alzheimer's disease.

Arnemann KL, Stöber F, Narayan S, Rabinovici GD, Jagust WJ.

Neuroimage Clin. 2017 Dec 28;17:987-999. doi: 10.1016/j.nicl.2017.12.037. eCollection 2018.

34.

Spontaneous eye blink rate and dopamine synthesis capacity: preliminary evidence for an absence of positive correlation.

Sescousse G, Ligneul R, van Holst RJ, Janssen LK, de Boer F, Janssen M, Berry AS, Jagust WJ, Cools R.

Eur J Neurosci. 2018 May;47(9):1081-1086. doi: 10.1111/ejn.13895. Epub 2018 Mar 26.

35.

Following the pathway to Alzheimer's disease.

Jagust W.

Nat Neurosci. 2018 Mar;21(3):306-308. doi: 10.1038/s41593-018-0085-5. No abstract available.

PMID:
29476126
36.

Rates of Amyloid Imaging Positivity in Patients With Primary Progressive Aphasia.

Santos-Santos MA, Rabinovici GD, Iaccarino L, Ayakta N, Tammewar G, Lobach I, Henry ML, Hubbard I, Mandelli ML, Spinelli E, Miller ZA, Pressman PS, O'Neil JP, Ghosh P, Lazaris A, Meyer M, Watson C, Yoon SJ, Rosen HJ, Grinberg L, Seeley WW, Miller BL, Jagust WJ, Gorno-Tempini ML.

JAMA Neurol. 2018 Mar 1;75(3):342-352. doi: 10.1001/jamaneurol.2017.4309.

37.

Associations between [18F]AV1451 tau PET and CSF measures of tau pathology in a clinical sample.

La Joie R, Bejanin A, Fagan AM, Ayakta N, Baker SL, Bourakova V, Boxer AL, Cha J, Karydas A, Jerome G, Maass A, Mensing A, Miller ZA, O'Neil JP, Pham J, Rosen HJ, Tsai R, Visani AV, Miller BL, Jagust WJ, Rabinovici GD.

Neurology. 2018 Jan 23;90(4):e282-e290. doi: 10.1212/WNL.0000000000004860. Epub 2017 Dec 27.

38.

Old Brains Come Uncoupled in Sleep: Slow Wave-Spindle Synchrony, Brain Atrophy, and Forgetting.

Helfrich RF, Mander BA, Jagust WJ, Knight RT, Walker MP.

Neuron. 2018 Jan 3;97(1):221-230.e4. doi: 10.1016/j.neuron.2017.11.020. Epub 2017 Dec 14.

39.

Associations Between Tau, β-Amyloid, and Cognition in Parkinson Disease.

Winer JR, Maass A, Pressman P, Stiver J, Schonhaut DR, Baker SL, Kramer J, Rabinovici GD, Jagust WJ.

JAMA Neurol. 2018 Feb 1;75(2):227-235. doi: 10.1001/jamaneurol.2017.3713.

40.

Entorhinal Tau Pathology, Episodic Memory Decline, and Neurodegeneration in Aging.

Maass A, Lockhart SN, Harrison TM, Bell RK, Mellinger T, Swinnerton K, Baker SL, Rabinovici GD, Jagust WJ.

J Neurosci. 2018 Jan 17;38(3):530-543. doi: 10.1523/JNEUROSCI.2028-17.2017. Epub 2017 Nov 30.

41.

Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia.

Jansen WJ, Ossenkoppele R, Tijms BM, Fagan AM, Hansson O, Klunk WE, van der Flier WM, Villemagne VL, Frisoni GB, Fleisher AS, Lleó A, Mintun MA, Wallin A, Engelborghs S, Na DL, Chételat G, Molinuevo JL, Landau SM, Mattsson N, Kornhuber J, Sabri O, Rowe CC, Parnetti L, Popp J, Fladby T, Jagust WJ, Aalten P, Lee DY, Vandenberghe R, Resende de Oliveira C, Kapaki E, Froelich L, Ivanoiu A, Gabryelewicz T, Verbeek MM, Sanchez-Juan P, Hildebrandt H, Camus V, Zboch M, Brooks DJ, Drzezga A, Rinne JO, Newberg A, de Mendonça A, Sarazin M, Rabinovici GD, Madsen K, Kramberger MG, Nordberg A, Mok V, Mroczko B, Wolk DA, Meyer PT, Tsolaki M, Scheltens P, Verhey FRJ, Visser PJ; Amyloid Biomarker Study Group, Aarsland D, Alcolea D, Alexander M, Almdahl IS, Arnold SE, Baldeiras I, Barthel H, van Berckel BNM, Blennow K, van Buchem MA, Cavedo E, Chen K, Chipi E, Cohen AD, Förster S, Fortea J, Frederiksen KS, Freund-Levi Y, Gkatzima O, Gordon MF, Grimmer T, Hampel H, Hausner L, Hellwig S, Herukka SK, Johannsen P, Klimkowicz-Mrowiec A, Köhler S, Koglin N, van Laere K, de Leon M, Lisetti V, Maier W, Marcusson J, Meulenbroek O, Møllergård HM, Morris JC, Nordlund A, Novak GP, Paraskevas GP, Perera G, Peters O, Ramakers IHGB, Rami L, Rodríguez-Rodríguez E, Roe CM, Rot U, Rüther E, Santana I, Schröder J, Seo SW, Soininen H, Spiru L, Stomrud E, Struyfs H, Teunissen CE, Vos SJB, van Waalwijk van Doorn LJC, Waldemar G, Wallin ÅK, Wiltfang J, Zetterberg H.

JAMA Psychiatry. 2018 Jan 1;75(1):84-95. doi: 10.1001/jamapsychiatry.2017.3391. Erratum in: JAMA Psychiatry. 2018 Mar 1;75(3):303.

42.

Local and distant relationships between amyloid, tau and neurodegeneration in Alzheimer's Disease.

Iaccarino L, Tammewar G, Ayakta N, Baker SL, Bejanin A, Boxer AL, Gorno-Tempini ML, Janabi M, Kramer JH, Lazaris A, Lockhart SN, Miller BL, Miller ZA, O'Neil JP, Ossenkoppele R, Rosen HJ, Schonhaut DR, Jagust WJ, Rabinovici GD.

Neuroimage Clin. 2017 Sep 25;17:452-464. doi: 10.1016/j.nicl.2017.09.016. eCollection 2018.

43.

Head to head comparison of [18F] AV-1451 and [18F] THK5351 for tau imaging in Alzheimer's disease and frontotemporal dementia.

Jang YK, Lyoo CH, Park S, Oh SJ, Cho H, Oh M, Ryu YH, Choi JY, Rabinovici GD, Kim HJ, Moon SH, Jang H, Lee JS, Jagust WJ, Na DL, Kim JS, Seo SW.

Eur J Nucl Med Mol Imaging. 2018 Mar;45(3):432-442. doi: 10.1007/s00259-017-3876-0. Epub 2017 Nov 16.

44.

Considerations and code for partial volume correcting [18F]-AV-1451 tau PET data.

Baker SL, Maass A, Jagust WJ.

Data Brief. 2017 Oct 16;15:648-657. doi: 10.1016/j.dib.2017.10.024. eCollection 2017 Dec.

45.

Earliest accumulation of β-amyloid occurs within the default-mode network and concurrently affects brain connectivity.

Palmqvist S, Schöll M, Strandberg O, Mattsson N, Stomrud E, Zetterberg H, Blennow K, Landau S, Jagust W, Hansson O.

Nat Commun. 2017 Oct 31;8(1):1214. doi: 10.1038/s41467-017-01150-x.

46.

White Matter Structure in Older Adults Moderates the Benefit of Sleep Spindles on Motor Memory Consolidation.

Mander BA, Zhu AH, Lindquist JR, Villeneuve S, Rao V, Lu B, Saletin JM, Ancoli-Israel S, Jagust WJ, Walker MP.

J Neurosci. 2017 Nov 29;37(48):11675-11687. doi: 10.1523/JNEUROSCI.3033-16.2017. Epub 2017 Oct 30.

47.

Tau pathology and neurodegeneration contribute to cognitive impairment in Alzheimer's disease.

Bejanin A, Schonhaut DR, La Joie R, Kramer JH, Baker SL, Sosa N, Ayakta N, Cantwell A, Janabi M, Lauriola M, O'Neil JP, Gorno-Tempini ML, Miller ZA, Rosen HJ, Miller BL, Jagust WJ, Rabinovici GD.

Brain. 2017 Dec 1;140(12):3286-3300. doi: 10.1093/brain/awx243.

48.

Subjective cognitive decline and β-amyloid burden predict cognitive change in healthy elderly.

Vogel JW, Varga Doležalová M, La Joie R, Marks SM, Schwimmer HD, Landau SM, Jagust WJ.

Neurology. 2017 Nov 7;89(19):2002-2009. doi: 10.1212/WNL.0000000000004627. Epub 2017 Oct 6.

49.

18 F-flortaucipir tau positron emission tomography distinguishes established progressive supranuclear palsy from controls and Parkinson disease: A multicenter study.

Schonhaut DR, McMillan CT, Spina S, Dickerson BC, Siderowf A, Devous MD Sr, Tsai R, Winer J, Russell DS, Litvan I, Roberson ED, Seeley WW, Grinberg LT, Kramer JH, Miller BL, Pressman P, Nasrallah I, Baker SL, Gomperts SN, Johnson KA, Grossman M, Jagust WJ, Boxer AL, Rabinovici GD.

Ann Neurol. 2017 Oct;82(4):622-634. doi: 10.1002/ana.25060.

50.

The Complexity of Subjective Cognitive Decline.

Ossenkoppele R, Jagust WJ.

JAMA Neurol. 2017 Dec 1;74(12):1400-1402. doi: 10.1001/jamaneurol.2017.2224. No abstract available.

PMID:
28973114

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