Send to

Choose Destination
Science. 1998 Apr 3;280(5360):104-6.

Arabidopsis CBF1 overexpression induces COR genes and enhances freezing tolerance.

Author information

Department of Crop and Soil Sciences, Plant and Soil Sciences Building, Michigan State University, East Lansing, MI 48824-1325, USA.


Many plants, including Arabidopsis, show increased resistance to freezing after they have been exposed to low nonfreezing temperatures. This response, termed cold acclimation, is associated with the induction of COR (cold-regulated) genes mediated by the C-repeat/drought-responsive element (CRT/DRE) DNA regulatory element. Increased expression of Arabidopsis CBF1, a transcriptional activator that binds to the CRT/DRE sequence, induced COR gene expression and increased the freezing tolerance of nonacclimated Arabidopsis plants. We conclude that CBF1 is a likely regulator of the cold acclimation response, controlling the level of COR gene expression, which in turn promotes tolerance to freezing.

[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for HighWire
Loading ...
Support Center