Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 97


Ano1 mediates pressure-sensitive contraction frequency changes in mouse lymphatic collecting vessels.

Zawieja SD, Castorena JA, Gui P, Li M, Bulley SA, Jaggar JH, Rock JR, Davis MJ.

J Gen Physiol. 2019 Apr 1;151(4):532-554. doi: 10.1085/jgp.201812294. Epub 2019 Mar 12.


Arterial smooth muscle cell PKD2 (TRPP1) channels regulate systemic blood pressure.

Bulley S, Fernández-Peña C, Hasan R, Leo MD, Muralidharan P, Mackay CE, Evanson KW, Moreira-Junior L, Mata-Daboin A, Burris SK, Wang Q, Kuruvilla KP, Jaggar JH.

Elife. 2018 Dec 4;7. pii: e42628. doi: 10.7554/eLife.42628.


Impaired Trafficking of β1 Subunits Inhibits BK Channels in Cerebral Arteries of Hypertensive Rats.

Leo MD, Zhai X, Yin W, Jaggar JH.

Hypertension. 2018 Sep;72(3):765-775. doi: 10.1161/HYPERTENSIONAHA.118.11147.


Calcium- and voltage-gated BK channels in vascular smooth muscle.

Dopico AM, Bukiya AN, Jaggar JH.

Pflugers Arch. 2018 Sep;470(9):1271-1289. doi: 10.1007/s00424-018-2151-y. Epub 2018 May 11. Review.


Elevated plasma catecholamines functionally compensate for the reduced myogenic tone in smooth muscle STIM1 knockout mice but with deleterious cardiac effects.

Pichavaram P, Yin W, Evanson KW, Jaggar JH, Mancarella S.

Cardiovasc Res. 2018 Apr 1;114(5):668-678. doi: 10.1093/cvr/cvy015.


Trafficking of BK channel subunits controls arterial contractility.

Leo MD, Jaggar JH.

Oncotarget. 2017 Nov 3;8(63):106149-106150. doi: 10.18632/oncotarget.22280. eCollection 2017 Dec 5. No abstract available.


KV channel trafficking and control of vascular tone.

Hasan R, Jaggar JH.

Microcirculation. 2018 Jan;25(1). doi: 10.1111/micc.12418. Review.


Endothelin-1 Stimulates Vasoconstriction Through Rab11A Serine 177 Phosphorylation.

Zhai X, Leo MD, Jaggar JH.

Circ Res. 2017 Sep 1;121(6):650-661. doi: 10.1161/CIRCRESAHA.117.311102. Epub 2017 Jul 10.


Membrane depolarization activates BK channels through ROCK-mediated β1 subunit surface trafficking to limit vasoconstriction.

Leo MD, Zhai X, Muralidharan P, Kuruvilla KP, Bulley S, Boop FA, Jaggar JH.

Sci Signal. 2017 May 9;10(478). pii: eaah5417. doi: 10.1126/scisignal.aah5417.


Science Signaling Podcast for 9 May 2017: Trafficking of BK channel subunits in arterial myocytes.

Jaggar JH, VanHook AM.

Sci Signal. 2017 May 9;10(478). pii: eaan4849. doi: 10.1126/scisignal.aan4849.


Corrigendum: Calmodulin is responsible for Ca2+-dependent regulation of TRPA1 Channels.

Hasan R, Leeson-Payne ATS, Jaggar JH, Zhang X.

Sci Rep. 2017 May 4;7:46588. doi: 10.1038/srep46588. No abstract available.


Calmodulin is responsible for Ca2+-dependent regulation of TRPA1 Channels.

Hasan R, Leeson-Payne AT, Jaggar JH, Zhang X.

Sci Rep. 2017 Mar 23;7:45098. doi: 10.1038/srep45098. Erratum in: Sci Rep. 2017 May 04;7:46588.


Angiotensin II reduces the surface abundance of KV 1.5 channels in arterial myocytes to stimulate vasoconstriction.

Kidd MW, Bulley S, Jaggar JH.

J Physiol. 2017 Mar 1;595(5):1607-1618. doi: 10.1113/JP272893. Epub 2017 Feb 5.


Calcium Channels and Oxidative Stress Mediate a Synergistic Disruption of Tight Junctions by Ethanol and Acetaldehyde in Caco-2 Cell Monolayers.

Samak G, Gangwar R, Meena AS, Rao RG, Shukla PK, Manda B, Narayanan D, Jaggar JH, Rao R.

Sci Rep. 2016 Dec 13;6:38899. doi: 10.1038/srep38899.


Now you see it, now you don't: the changing face of endothelin-1 signalling during vascular ontogenesis.

Bulley S, Jaggar JH.

J Physiol. 2016 Sep 1;594(17):4703-4. doi: 10.1113/JP272564. No abstract available.


Local coupling of TRPC6 to ANO1/TMEM16A channels in smooth muscle cells amplifies vasoconstriction in cerebral arteries.

Wang Q, Leo MD, Narayanan D, Kuruvilla KP, Jaggar JH.

Am J Physiol Cell Physiol. 2016 Jun 1;310(11):C1001-9. doi: 10.1152/ajpcell.00092.2016. Epub 2016 May 4.


Rab25 influences functional Cav1.2 channel surface expression in arterial smooth muscle cells.

Bannister JP, Bulley S, Leo MD, Kidd MW, Jaggar JH.

Am J Physiol Cell Physiol. 2016 Jun 1;310(11):C885-93. doi: 10.1152/ajpcell.00345.2015. Epub 2016 Apr 13.


Intravascular pressure enhances the abundance of functional Kv1.5 channels at the surface of arterial smooth muscle cells.

Kidd MW, Leo MD, Bannister JP, Jaggar JH.

Sci Signal. 2015 Aug 18;8(390):ra83. doi: 10.1126/scisignal.aac5128.


Angiotensin II stimulates internalization and degradation of arterial myocyte plasma membrane BK channels to induce vasoconstriction.

Leo MD, Bulley S, Bannister JP, Kuruvilla KP, Narayanan D, Jaggar JH.

Am J Physiol Cell Physiol. 2015 Sep 15;309(6):C392-402. doi: 10.1152/ajpcell.00127.2015. Epub 2015 Jul 15.


Eugenol dilates mesenteric arteries and reduces systemic BP by activating endothelial cell TRPV4 channels.

Peixoto-Neves D, Wang Q, Leal-Cardoso JH, Rossoni LV, Jaggar JH.

Br J Pharmacol. 2015 Jul;172(14):3484-94. doi: 10.1111/bph.13156. Epub 2015 May 19.


9-Phenanthrol inhibits recombinant and arterial myocyte TMEM16A channels.

Burris SK, Wang Q, Bulley S, Neeb ZP, Jaggar JH.

Br J Pharmacol. 2015 May;172(10):2459-68. doi: 10.1111/bph.13077. Epub 2015 Mar 24.


Localized TRPA1 channel Ca2+ signals stimulated by reactive oxygen species promote cerebral artery dilation.

Sullivan MN, Gonzales AL, Pires PW, Bruhl A, Leo MD, Li W, Oulidi A, Boop FA, Feng Y, Jaggar JH, Welsh DG, Earley S.

Sci Signal. 2015 Jan 6;8(358):ra2. doi: 10.1126/scisignal.2005659.


Calcium/Ask1/MKK7/JNK2/c-Src signalling cascade mediates disruption of intestinal epithelial tight junctions by dextran sulfate sodium.

Samak G, Chaudhry KK, Gangwar R, Narayanan D, Jaggar JH, Rao R.

Biochem J. 2015 Feb 1;465(3):503-15. doi: 10.1042/BJ20140450.


Contributions of KATP and KCa channels to cerebral arteriolar dilation to hypercapnia in neonatal brain.

Nnorom CC, Davis C, Fedinec AL, Howell K, Jaggar JH, Parfenova H, Pourcyrous M, Leffler CW.

Physiol Rep. 2014 Aug 28;2(8). pii: e12127. doi: 10.14814/phy2.12127. Print 2014 Aug 1.


Large conductance Ca2+-activated K+ channel (BKCa) α-subunit splice variants in resistance arteries from rat cerebral and skeletal muscle vasculature.

Nourian Z, Li M, Leo MD, Jaggar JH, Braun AP, Hill MA.

PLoS One. 2014 Jun 12;9(6):e98863. doi: 10.1371/journal.pone.0098863. eCollection 2014.


Eugenol dilates rat cerebral arteries by inhibiting smooth muscle cell voltage-dependent calcium channels.

Peixoto-Neves D, Leal-Cardoso JH, Jaggar JH.

J Cardiovasc Pharmacol. 2014 Nov;64(5):401-6. doi: 10.1097/FJC.0000000000000131.


LRRC26 is a functional BK channel auxiliary γ subunit in arterial smooth muscle cells.

Evanson KW, Bannister JP, Leo MD, Jaggar JH.

Circ Res. 2014 Aug 1;115(4):423-31. doi: 10.1161/CIRCRESAHA.115.303407. Epub 2014 Jun 6.


Type 2 ryanodine receptors are highly sensitive to alcohol.

Ye Y, Jian K, Jaggar JH, Bukiya AN, Dopico AM.

FEBS Lett. 2014 May 2;588(9):1659-65. doi: 10.1016/j.febslet.2014.03.005. Epub 2014 Mar 12.


Dynamic regulation of β1 subunit trafficking controls vascular contractility.

Leo MD, Bannister JP, Narayanan D, Nair A, Grubbs JE, Gabrick KS, Boop FA, Jaggar JH.

Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2361-6. doi: 10.1073/pnas.1317527111. Epub 2014 Jan 24.


Cl⁻ channels in smooth muscle cells.

Bulley S, Jaggar JH.

Pflugers Arch. 2014 May;466(5):861-72. Review. Erratum in: Pflugers Arch. 2014 May;466(5):873.


Smooth muscle cell transient receptor potential polycystin-2 (TRPP2) channels contribute to the myogenic response in cerebral arteries.

Narayanan D, Bulley S, Leo MD, Burris SK, Gabrick KS, Boop FA, Jaggar JH.

J Physiol. 2013 Oct 15;591(20):5031-46. doi: 10.1113/jphysiol.2013.258319. Epub 2013 Jul 15.


The voltage-dependent L-type Ca2+ (CaV1.2) channel C-terminus fragment is a bi-modal vasodilator.

Bannister JP, Leo MD, Narayanan D, Jangsangthong W, Nair A, Evanson KW, Pachuau J, Gabrick KS, Boop FA, Jaggar JH.

J Physiol. 2013 Jun 15;591(12):2987-98. doi: 10.1113/jphysiol.2013.251926. Epub 2013 Apr 8.


Regulation of interleukin-6 secretion by the two-pore-domain potassium channel Trek-1 in alveolar epithelial cells.

Schwingshackl A, Teng B, Ghosh M, Lim KG, Tigyi G, Narayanan D, Jaggar JH, Waters CM.

Am J Physiol Lung Cell Mol Physiol. 2013 Feb 15;304(4):L276-86. doi: 10.1152/ajplung.00299.2012. Epub 2012 Dec 28.


An elevation in physical coupling of type 1 inositol 1,4,5-trisphosphate (IP3) receptors to transient receptor potential 3 (TRPC3) channels constricts mesenteric arteries in genetic hypertension.

Adebiyi A, Thomas-Gatewood CM, Leo MD, Kidd MW, Neeb ZP, Jaggar JH.

Hypertension. 2012 Nov;60(5):1213-9. doi: 10.1161/HYPERTENSIONAHA.112.198820. Epub 2012 Oct 8.


Transcriptional upregulation of α2δ-1 elevates arterial smooth muscle cell voltage-dependent Ca2+ channel surface expression and cerebrovascular constriction in genetic hypertension.

Bannister JP, Bulley S, Narayanan D, Thomas-Gatewood C, Luzny P, Pachuau J, Jaggar JH.

Hypertension. 2012 Oct;60(4):1006-15. doi: 10.1161/HYPERTENSIONAHA.112.199661. Epub 2012 Sep 4.


TMEM16A/ANO1 channels contribute to the myogenic response in cerebral arteries.

Bulley S, Neeb ZP, Burris SK, Bannister JP, Thomas-Gatewood CM, Jangsangthong W, Jaggar JH.

Circ Res. 2012 Sep 28;111(8):1027-36. Epub 2012 Aug 7.


Hydrogen sulfide activates Ca²⁺ sparks to induce cerebral arteriole dilatation.

Liang GH, Xi Q, Leffler CW, Jaggar JH.

J Physiol. 2012 Jun 1;590(11):2709-20. doi: 10.1113/jphysiol.2011.225128. Epub 2012 Apr 16.


Inositol trisphosphate receptors in smooth muscle cells.

Narayanan D, Adebiyi A, Jaggar JH.

Am J Physiol Heart Circ Physiol. 2012 Jun 1;302(11):H2190-210. doi: 10.1152/ajpheart.01146.2011. Epub 2012 Mar 23. Review.


TMEM16A channels generate Ca²⁺-activated Cl⁻ currents in cerebral artery smooth muscle cells.

Thomas-Gatewood C, Neeb ZP, Bulley S, Adebiyi A, Bannister JP, Leo MD, Jaggar JH.

Am J Physiol Heart Circ Physiol. 2011 Nov;301(5):H1819-27. doi: 10.1152/ajpheart.00404.2011. Epub 2011 Aug 19.


Vasodilation induced by oxygen/glucose deprivation is attenuated in cerebral arteries of SUR2 null mice.

Adebiyi A, McNally EM, Jaggar JH.

Am J Physiol Heart Circ Physiol. 2011 Oct;301(4):H1360-8. doi: 10.1152/ajpheart.00406.2011. Epub 2011 Jul 22.


CaV1.3 channels and intracellular calcium mediate osmotic stress-induced N-terminal c-Jun kinase activation and disruption of tight junctions in Caco-2 CELL MONOLAYERS.

Samak G, Narayanan D, Jaggar JH, Rao R.

J Biol Chem. 2011 Aug 26;286(34):30232-43. doi: 10.1074/jbc.M111.240358. Epub 2011 Jul 7.


Glutamate-induced calcium signals stimulate CO production in piglet astrocytes.

Xi Q, Tcheranova D, Basuroy S, Parfenova H, Jaggar JH, Leffler CW.

Am J Physiol Heart Circ Physiol. 2011 Aug;301(2):H428-33. doi: 10.1152/ajpheart.01277.2010. Epub 2011 May 13.


Carbon monoxide as an endogenous vascular modulator.

Leffler CW, Parfenova H, Jaggar JH.

Am J Physiol Heart Circ Physiol. 2011 Jul;301(1):H1-H11. doi: 10.1152/ajpheart.00230.2011. Epub 2011 Apr 15. Review.


Hydrogen sulfide dilates cerebral arterioles by activating smooth muscle cell plasma membrane KATP channels.

Liang GH, Adebiyi A, Leo MD, McNally EM, Leffler CW, Jaggar JH.

Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2088-95. doi: 10.1152/ajpheart.01290.2010. Epub 2011 Mar 18.


Ca(V)1.2 channel N-terminal splice variants modulate functional surface expression in resistance size artery smooth muscle cells.

Bannister JP, Thomas-Gatewood CM, Neeb ZP, Adebiyi A, Cheng X, Jaggar JH.

J Biol Chem. 2011 Apr 29;286(17):15058-66. doi: 10.1074/jbc.M110.182816. Epub 2011 Feb 28.


Hydrogen sulfide and cerebral microvascular tone in newborn pigs.

Leffler CW, Parfenova H, Basuroy S, Jaggar JH, Umstot ES, Fedinec AL.

Am J Physiol Heart Circ Physiol. 2011 Feb;300(2):H440-7. doi: 10.1152/ajpheart.00722.2010. Epub 2010 Dec 3.


Type 1 IP3 receptors activate BKCa channels via local molecular coupling in arterial smooth muscle cells.

Zhao G, Neeb ZP, Leo MD, Pachuau J, Adebiyi A, Ouyang K, Chen J, Jaggar JH.

J Gen Physiol. 2010 Sep;136(3):283-91. doi: 10.1085/jgp.201010453. Epub 2010 Aug 16.


Mitochondria control functional CaV1.2 expression in smooth muscle cells of cerebral arteries.

Narayanan D, Xi Q, Pfeffer LM, Jaggar JH.

Circ Res. 2010 Sep 3;107(5):631-41. doi: 10.1161/CIRCRESAHA.110.224345. Epub 2010 Jul 8.


Vasoconstriction resulting from dynamic membrane trafficking of TRPM4 in vascular smooth muscle cells.

Crnich R, Amberg GC, Leo MD, Gonzales AL, Tamkun MM, Jaggar JH, Earley S.

Am J Physiol Cell Physiol. 2010 Sep;299(3):C682-94. doi: 10.1152/ajpcell.00101.2010. Epub 2010 Jul 7.

Supplemental Content

Loading ...
Support Center