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Items: 37

1.

Mitochondrial Dysfunction in Astrocytes Impairs the Generation of Reactive Astrocytes and Enhances Neuronal Cell Death in the Cortex Upon Photothrombotic Lesion.

Fiebig C, Keiner S, Ebert B, Schäffner I, Jagasia R, Lie DC, Beckervordersandforth R.

Front Mol Neurosci. 2019 Feb 22;12:40. doi: 10.3389/fnmol.2019.00040. eCollection 2019.

2.

Path mediation analysis reveals GBA impacts Lewy body disease status by increasing α-synuclein levels.

Gündner AL, Duran-Pacheco G, Zimmermann S, Ruf I, Moors T, Baumann K, Jagasia R, van de Berg WDJ, Kremer T.

Neurobiol Dis. 2019 Jan;121:205-213. doi: 10.1016/j.nbd.2018.09.015. Epub 2018 Sep 17.

PMID:
30236861
3.

Stem cell-derived neurons from autistic individuals with SHANK3 mutation show morphogenetic abnormalities during early development.

Kathuria A, Nowosiad P, Jagasia R, Aigner S, Taylor RD, Andreae LC, Gatford NJF, Lucchesi W, Srivastava DP, Price J.

Mol Psychiatry. 2018 Mar;23(3):735-746. doi: 10.1038/mp.2017.185. Epub 2017 Sep 26.

4.

Generation of a homozygous GBA deletion human embryonic stem cell line.

Gündner AL, Meyer CA, Aigner S, Christensen K, Patsch C, Jagasia R, Baumann K, Burcin M.

Stem Cell Res. 2017 Aug;23:122-126. doi: 10.1016/j.scr.2017.07.009. Epub 2017 Jul 11.

5.

Expansion of human midbrain floor plate progenitors from induced pluripotent stem cells increases dopaminergic neuron differentiation potential.

Fedele S, Collo G, Behr K, Bischofberger J, Müller S, Kunath T, Christensen K, Gündner AL, Graf M, Jagasia R, Taylor V.

Sci Rep. 2017 Jul 20;7(1):6036. doi: 10.1038/s41598-017-05633-1.

6.

Glypican-2 levels in cerebrospinal fluid predict the status of adult hippocampal neurogenesis.

Lugert S, Kremer T, Jagasia R, Herrmann A, Aigner S, Giachino C, Mendez-David I, Gardier AM, Carralot JP, Meistermann H, Augustin A, Saxe MD, Lamerz J, Duran-Pacheco G, Ducret A, Taylor V, David DJ, Czech C.

Sci Rep. 2017 Apr 25;7:46543. doi: 10.1038/srep46543.

7.

Role of Mitochondrial Metabolism in the Control of Early Lineage Progression and Aging Phenotypes in Adult Hippocampal Neurogenesis.

Beckervordersandforth R, Ebert B, Schäffner I, Moss J, Fiebig C, Shin J, Moore DL, Ghosh L, Trinchero MF, Stockburger C, Friedland K, Steib K, von Wittgenstein J, Keiner S, Redecker C, Hölter SM, Xiang W, Wurst W, Jagasia R, Schinder AF, Ming GL, Toni N, Jessberger S, Song H, Lie DC.

Neuron. 2017 Mar 22;93(6):1518. doi: 10.1016/j.neuron.2017.03.008. No abstract available.

8.

Role of Mitochondrial Metabolism in the Control of Early Lineage Progression and Aging Phenotypes in Adult Hippocampal Neurogenesis.

Beckervordersandforth R, Ebert B, Schäffner I, Moss J, Fiebig C, Shin J, Moore DL, Ghosh L, Trinchero MF, Stockburger C, Friedland K, Steib K, von Wittgenstein J, Keiner S, Redecker C, Hölter SM, Xiang W, Wurst W, Jagasia R, Schinder AF, Ming GL, Toni N, Jessberger S, Song H, Lie DC.

Neuron. 2017 Feb 8;93(3):560-573.e6. doi: 10.1016/j.neuron.2016.12.017. Epub 2017 Jan 19. Erratum in: Neuron. 2017 Mar 22;93(6):1518.

9.

Genomic analysis of the molecular neuropathology of tuberous sclerosis using a human stem cell model.

Grabole N, Zhang JD, Aigner S, Ruderisch N, Costa V, Weber FC, Theron M, Berntenis N, Spleiss O, Ebeling M, Yeo GW, Jagasia R, Kiialainen A.

Genome Med. 2016 Sep 21;8(1):94.

10.

mTORC1 Inhibition Corrects Neurodevelopmental and Synaptic Alterations in a Human Stem Cell Model of Tuberous Sclerosis.

Costa V, Aigner S, Vukcevic M, Sauter E, Behr K, Ebeling M, Dunkley T, Friedlein A, Zoffmann S, Meyer CA, Knoflach F, Lugert S, Patsch C, Fjeldskaar F, Chicha-Gaudimier L, Kiialainen A, Piraino P, Bedoucha M, Graf M, Jessberger S, Ghosh A, Bischofberger J, Jagasia R.

Cell Rep. 2016 Apr 5;15(1):86-95. doi: 10.1016/j.celrep.2016.02.090. Epub 2016 Mar 24.

11.

Generation of vascular endothelial and smooth muscle cells from human pluripotent stem cells.

Patsch C, Challet-Meylan L, Thoma EC, Urich E, Heckel T, O'Sullivan JF, Grainger SJ, Kapp FG, Sun L, Christensen K, Xia Y, Florido MH, He W, Pan W, Prummer M, Warren CR, Jakob-Roetne R, Certa U, Jagasia R, Freskgård PO, Adatto I, Kling D, Huang P, Zon LI, Chaikof EL, Gerszten RE, Graf M, Iacone R, Cowan CA.

Nat Cell Biol. 2015 Aug;17(8):994-1003. doi: 10.1038/ncb3205. Epub 2015 Jul 27.

12.

Role of adult hippocampal neurogenesis in cognition in physiology and disease: pharmacological targets and biomarkers.

Costa V, Lugert S, Jagasia R.

Handb Exp Pharmacol. 2015;228:99-155. doi: 10.1007/978-3-319-16522-6_4. Review.

PMID:
25977081
13.

Characterization of a human pluripotent stem cell-derived model of neuronal development using multiplexed targeted proteomics.

Dunkley T, Costa V, Friedlein A, Lugert S, Aigner S, Ebeling M, Miller MT, Patsch C, Piraino P, Cutler P, Jagasia R.

Proteomics Clin Appl. 2015 Aug;9(7-8):684-94. doi: 10.1002/prca.201400150. Epub 2015 May 26.

PMID:
25684324
14.

Chemical conversion of human fibroblasts into functional Schwann cells.

Thoma EC, Merkl C, Heckel T, Haab R, Knoflach F, Nowaczyk C, Flint N, Jagasia R, Jensen Zoffmann S, Truong HH, Petitjean P, Jessberger S, Graf M, Iacone R.

Stem Cell Reports. 2014 Oct 14;3(4):539-47. doi: 10.1016/j.stemcr.2014.07.014. Epub 2014 Sep 11.

15.

Mitochondria modify exercise-induced development of stem cell-derived neurons in the adult brain.

Steib K, Schäffner I, Jagasia R, Ebert B, Lie DC.

J Neurosci. 2014 May 7;34(19):6624-33. doi: 10.1523/JNEUROSCI.4972-13.2014.

16.

Using genetic findings in autism for the development of new pharmaceutical compounds.

Vorstman JA, Spooren W, Persico AM, Collier DA, Aigner S, Jagasia R, Glennon JC, Buitelaar JK.

Psychopharmacology (Berl). 2014 Mar;231(6):1063-78. doi: 10.1007/s00213-013-3334-z. Epub 2013 Nov 30. Review.

PMID:
24292384
17.

Human pluripotent stem cell models of autism spectrum disorder: emerging frontiers, opportunities, and challenges towards neuronal networks in a dish.

Aigner S, Heckel T, Zhang JD, Andreae LC, Jagasia R.

Psychopharmacology (Berl). 2014 Mar;231(6):1089-104. Review.

18.

Analysis of adult neurogenesis: evidence for a prominent "non-neurogenic" DCX-protein pool in rodent brain.

Kremer T, Jagasia R, Herrmann A, Matile H, Borroni E, Francis F, Kuhn HG, Czech C.

PLoS One. 2013 May 14;8(5):e59269. doi: 10.1371/journal.pone.0059269. Print 2013.

19.

Mitophagy is triggered by mild oxidative stress in a mitochondrial fission dependent manner.

Frank M, Duvezin-Caubet S, Koob S, Occhipinti A, Jagasia R, Petcherski A, Ruonala MO, Priault M, Salin B, Reichert AS.

Biochim Biophys Acta. 2012 Dec;1823(12):2297-310. doi: 10.1016/j.bbamcr.2012.08.007. Epub 2012 Aug 16.

20.

Prospero-related homeobox 1 gene (Prox1) is regulated by canonical Wnt signaling and has a stage-specific role in adult hippocampal neurogenesis.

Karalay O, Doberauer K, Vadodaria KC, Knobloch M, Berti L, Miquelajauregui A, Schwark M, Jagasia R, Taketo MM, Tarabykin V, Lie DC, Jessberger S.

Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5807-12. doi: 10.1073/pnas.1013456108. Epub 2011 Mar 21.

21.

Clonal analysis by distinct viral vectors identifies bona fide neural stem cells in the adult zebrafish telencephalon and characterizes their division properties and fate.

Rothenaigner I, Krecsmarik M, Hayes JA, Bahn B, Lepier A, Fortin G, Götz M, Jagasia R, Bally-Cuif L.

Development. 2011 Apr;138(8):1459-69. doi: 10.1242/dev.058156. Epub 2011 Mar 2.

22.

CREB signalling regulates early survival, neuronal gene expression and morphological development in adult subventricular zone neurogenesis.

Herold S, Jagasia R, Merz K, Wassmer K, Lie DC.

Mol Cell Neurosci. 2011 Jan;46(1):79-88. doi: 10.1016/j.mcn.2010.08.008. Epub 2010 Aug 27.

PMID:
20801218
23.

GABA-cAMP response element-binding protein signaling regulates maturation and survival of newly generated neurons in the adult hippocampus.

Jagasia R, Steib K, Englberger E, Herold S, Faus-Kessler T, Saxe M, Gage FH, Song H, Lie DC.

J Neurosci. 2009 Jun 24;29(25):7966-77. doi: 10.1523/JNEUROSCI.1054-09.2009.

24.

Formation of cristae and crista junctions in mitochondria depends on antagonism between Fcj1 and Su e/g.

Rabl R, Soubannier V, Scholz R, Vogel F, Mendl N, Vasiljev-Neumeyer A, Körner C, Jagasia R, Keil T, Baumeister W, Cyrklaff M, Neupert W, Reichert AS.

J Cell Biol. 2009 Jun 15;185(6):1047-63. doi: 10.1083/jcb.200811099.

25.

Peptide cyclization and cyclodimerization by Cu(I)-mediated azide-alkyne cycloaddition.

Jagasia R, Holub JM, Bollinger M, Kirshenbaum K, Finn MG.

J Org Chem. 2009 Apr 17;74(8):2964-74. doi: 10.1021/jo802097m.

26.

Infection control by antibody disruption of bacterial quorum sensing signaling.

Park J, Jagasia R, Kaufmann GF, Mathison JC, Ruiz DI, Moss JA, Meijler MM, Ulevitch RJ, Janda KD.

Chem Biol. 2007 Oct;14(10):1119-27.

27.

Adult neurogenesis in non-mammalian vertebrates.

Chapouton P, Jagasia R, Bally-Cuif L.

Bioessays. 2007 Aug;29(8):745-57. Review.

PMID:
17621643
28.

OPA1 processing reconstituted in yeast depends on the subunit composition of the m-AAA protease in mitochondria.

Duvezin-Caubet S, Koppen M, Wagener J, Zick M, Israel L, Bernacchia A, Jagasia R, Rugarli EI, Imhof A, Neupert W, Langer T, Reichert AS.

Mol Biol Cell. 2007 Sep;18(9):3582-90. Epub 2007 Jul 5.

29.

Molecular regulation of adult hippocampal neurogenesis.

Badde A, Jagasia R, Lie D.

J Stem Cells Regen Med. 2007 May 16;2(1):49. eCollection 2007. No abstract available.

PMID:
24692899
30.

Proteolytic processing of OPA1 links mitochondrial dysfunction to alterations in mitochondrial morphology.

Duvezin-Caubet S, Jagasia R, Wagener J, Hofmann S, Trifunovic A, Hansson A, Chomyn A, Bauer MF, Attardi G, Larsson NG, Neupert W, Reichert AS.

J Biol Chem. 2006 Dec 8;281(49):37972-9. Epub 2006 Sep 26.

31.

New regulators in adult neurogenesis and their potential role for repair.

Jagasia R, Song H, Gage FH, Lie DC.

Trends Mol Med. 2006 Sep;12(9):400-5. Epub 2006 Aug 4.

PMID:
16890023
32.

Microglia Kv1.3 channels contribute to their ability to kill neurons.

Fordyce CB, Jagasia R, Zhu X, Schlichter LC.

J Neurosci. 2005 Aug 3;25(31):7139-49.

33.

DRP-1-mediated mitochondrial fragmentation during EGL-1-induced cell death in C. elegans.

Jagasia R, Grote P, Westermann B, Conradt B.

Nature. 2005 Feb 17;433(7027):754-60.

34.

Design of a directed molecular network.

Ashkenasy G, Jagasia R, Yadav M, Ghadiri MR.

Proc Natl Acad Sci U S A. 2004 Jul 27;101(30):10872-7. Epub 2004 Jul 15.

35.

Study of the effect of small dose of steroid to ephedrine--theophylline combination in chronic obstructive pulmonary disease.

Kamat SR, Hoskote VR, Jagasia RS, Shah DC, Tyagi NK.

J Postgrad Med. 1983 Jul;29(3):139-50. No abstract available.

36.

Optimum dose of histamine for maximal acid output in underweight subjects.

Jagasia RS, Pimparkar BD.

Am J Gastroenterol. 1976 Jul;66(1):49-56.

PMID:
970386
37.

Experiences with various preparations of ephedrine theophylline combination in chronic obstructive pulmonary disease.

Kamat SR, Panandikar SG, Purohit SD, Jagasia RS, Kulkarni ST.

Indian J Chest Dis Allied Sci. 1976 Jan;18(1):25-35. No abstract available.

PMID:
1270089

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