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Items: 22


Chromatin-mediated translational control is essential for neural cell fate specification.

Hwang DW, Jaganathan A, Shrestha P, Jin Y, El-Amine N, Wang SH, Hammell M, Mills AA.

Life Sci Alliance. 2018 Aug 23;1(4):e201700016. doi: 10.26508/lsa.201700016. eCollection 2018 Aug.


Inhibitor of CBP Histone Acetyltransferase Downregulates p53 Activation and Facilitates Methylation at Lysine 27 on Histone H3.

Vincek AS, Patel J, Jaganathan A, Green A, Pierre-Louis V, Arora V, Rehmann J, Mezei M, Zhou MM, Ohlmeyer M, Mujtaba S.

Molecules. 2018 Aug 2;23(8). pii: E1930. doi: 10.3390/molecules23081930.


Absolute and relative facial selectivities in organocatalytic asymmetric chlorocyclization reactions.

Salehi Marzijarani N, Yousefi R, Jaganathan A, Ashtekar KD, Jackson JE, Borhan B.

Chem Sci. 2018 Jan 2;9(11):2898-2908. doi: 10.1039/c7sc04430e. eCollection 2018 Mar 21.


Biosurfactants produced by Bacillus subtilis A1 and Pseudomonas stutzeri NA3 reduce longevity and fecundity of Anopheles stephensi and show high toxicity against young instars.

Parthipan P, Sarankumar RK, Jaganathan A, Amuthavalli P, Babujanarthanam R, Rahman PKSM, Murugan K, Higuchi A, Benelli G, Rajasekar A.

Environ Sci Pollut Res Int. 2018 Apr;25(11):10471-10481. doi: 10.1007/s11356-017-0105-0. Epub 2017 Sep 21.


BET N-terminal bromodomain inhibition selectively blocks Th17 cell differentiation and ameliorates colitis in mice.

Cheung K, Lu G, Sharma R, Vincek A, Zhang R, Plotnikov AN, Zhang F, Zhang Q, Ju Y, Hu Y, Zhao L, Han X, Meslamani J, Xu F, Jaganathan A, Shen T, Zhu H, Rusinova E, Zeng L, Zhou J, Yang J, Peng L, Ohlmeyer M, Walsh MJ, Zhang DY, Xiong H, Zhou MM.

Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):2952-2957. doi: 10.1073/pnas.1615601114. Epub 2017 Mar 6.


Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation.

Cheung KL, Zhang F, Jaganathan A, Sharma R, Zhang Q, Konuma T, Shen T, Lee JY, Ren C, Chen CH, Lu G, Olson MR, Zhang W, Kaplan MH, Littman DR, Walsh MJ, Xiong H, Zeng L, Zhou MM.

Mol Cell. 2017 Mar 16;65(6):1068-1080.e5. doi: 10.1016/j.molcel.2016.12.022. Epub 2017 Mar 3.


Highly Regio- and Enantioselective Vicinal Dihalogenation of Allyl Amides.

Soltanzadeh B, Jaganathan A, Yi Y, Yi H, Staples RJ, Borhan B.

J Am Chem Soc. 2017 Feb 15;139(6):2132-2135. doi: 10.1021/jacs.6b09203. Epub 2017 Feb 3.


Magnetic nanoparticles are highly toxic to chloroquine-resistant Plasmodium falciparum, dengue virus (DEN-2), and their mosquito vectors.

Murugan K, Wei J, Alsalhi MS, Nicoletti M, Paulpandi M, Samidoss CM, Dinesh D, Chandramohan B, Paneerselvam C, Subramaniam J, Vadivalagan C, Wei H, Amuthavalli P, Jaganathan A, Devanesan S, Higuchi A, Kumar S, Aziz AT, Nataraj D, Vaseeharan B, Canale A, Benelli G.

Parasitol Res. 2017 Feb;116(2):495-502. doi: 10.1007/s00436-016-5310-0. Epub 2016 Nov 4.


Aqueous Suzuki Coupling Reactions of Basic Nitrogen-Containing Substrates in the Absence of Added Base and Ligand: Observation of High Yields under Acidic Conditions.

Li Z, Gelbaum C, Fisk JS, Holden B, Jaganathan A, Whiteker GT, Pollet P, Liotta CL.

J Org Chem. 2016 Sep 16;81(18):8520-9. doi: 10.1021/acs.joc.6b01683. Epub 2016 Sep 1.


Earthworm-mediated synthesis of silver nanoparticles: A potent tool against hepatocellular carcinoma, Plasmodium falciparum parasites and malaria mosquitoes.

Jaganathan A, Murugan K, Panneerselvam C, Madhiyazhagan P, Dinesh D, Vadivalagan C, Aziz AT, Chandramohan B, Suresh U, Rajaganesh R, Subramaniam J, Nicoletti M, Higuchi A, Alarfaj AA, Munusamy MA, Kumar S, Benelli G.

Parasitol Int. 2016 Jun;65(3):276-84. doi: 10.1016/j.parint.2016.02.003. Epub 2016 Feb 9.


Highly Stereoselective, Intermolecular Haloetherification and Haloesterification of Allyl Amides.

Soltanzadeh B, Jaganathan A, Borhan B.

Synlett. 2016 Feb;27(3):A25-A28. Epub 2016 Jan 19. No abstract available.


Highly Stereoselective Intermolecular Haloetherification and Haloesterification of Allyl Amides.

Soltanzadeh B, Jaganathan A, Staples RJ, Borhan B.

Angew Chem Int Ed Engl. 2015 Aug 10;54(33):9517-22. doi: 10.1002/anie.201502341. Epub 2015 Jun 25.


A new tool to guide halofunctionalization reactions: the halenium affinity (HalA) scale.

Ashtekar KD, Marzijarani NS, Jaganathan A, Holmes D, Jackson JE, Borhan B.

J Am Chem Soc. 2014 Sep 24;136(38):13355-62. doi: 10.1021/ja506889c. Epub 2014 Sep 11.


Chlorosulfonamide salts are superior electrophilic chlorine precursors for the organocatalytic asymmetric chlorocyclization of unsaturated amides.

Jaganathan A, Borhan B.

Org Lett. 2014 Jul 18;16(14):3616-9. doi: 10.1021/ol500861z. Epub 2014 Jun 30.


Coactivator MYST1 regulates nuclear factor-κB and androgen receptor functions during proliferation of prostate cancer cells.

Jaganathan A, Chaurasia P, Xiao GQ, Philizaire M, Lv X, Yao S, Burnstein KL, Liu DP, Levine AC, Mujtaba S.

Mol Endocrinol. 2014 Jun;28(6):872-85. doi: 10.1210/me.2014-1055. Epub 2014 Apr 4.


Kinetic resolution of unsaturated amides in a chlorocyclization reaction: concomitant enantiomer differentiation and face selective alkene chlorination by a single catalyst.

Jaganathan A, Staples RJ, Borhan B.

J Am Chem Soc. 2013 Oct 2;135(39):14806-13. doi: 10.1021/ja407241d. Epub 2013 Sep 17.


Anthrax SET protein: a potential virulence determinant that epigenetically represses NF-κB activation in infected macrophages.

Mujtaba S, Winer BY, Jaganathan A, Patel J, Sgobba M, Schuch R, Gupta YK, Haider S, Wang R, Fischetti VA.

J Biol Chem. 2013 Aug 9;288(32):23458-72. doi: 10.1074/jbc.M113.467696. Epub 2013 May 29.


Solvent-dependent enantiodivergence in the chlorocyclization of unsaturated carbamates.

Garzan A, Jaganathan A, Salehi Marzijarani N, Yousefi R, Whitehead DC, Jackson JE, Borhan B.

Chemistry. 2013 Jul 1;19(27):9015-21. doi: 10.1002/chem.201300189. Epub 2013 May 13.


Intensity-modulated radiation to spare neural stem cells in brain tumors: a computational platform for evaluation of physical and biological dose metrics.

Jaganathan A, Tiwari M, Phansekar R, Panta R, Huilgol N.

J Cancer Res Ther. 2011 Jan-Mar;7(1):58-63. doi: 10.4103/0973-1482.80463.


A catalytic asymmetric chlorocyclization of unsaturated amides.

Jaganathan A, Garzan A, Whitehead DC, Staples RJ, Borhan B.

Angew Chem Int Ed Engl. 2011 Mar 7;50(11):2593-6. doi: 10.1002/anie.201006910. Epub 2011 Feb 17. No abstract available.


An organocatalytic asymmetric chlorolactonization.

Whitehead DC, Yousefi R, Jaganathan A, Borhan B.

J Am Chem Soc. 2010 Mar 17;132(10):3298-300. doi: 10.1021/ja100502f.


Gestational and neonatal-onset hypothyroidism alters androgen receptor status in rat prostate glands at adulthood.

Aruldhas MM, Ramalingam N, Jaganathan A, John Sashi AM, Stanley JA, Nagappan AS, Vasavan J, Kannan A, Seshadri VN.

Prostate. 2010 May 15;70(7):689-700. doi: 10.1002/pros.21101.


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