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Items: 12

1.

The Histone Methyltransferase Inhibitor A-366 Uncovers a Role for G9a/GLP in the Epigenetics of Leukemia.

Pappano WN, Guo J, He Y, Ferguson D, Jagadeeswaran S, Osterling DJ, Gao W, Spence JK, Pliushchev M, Sweis RF, Buchanan FG, Michaelides MR, Shoemaker AR, Tse C, Chiang GG.

PLoS One. 2015 Jul 6;10(7):e0131716. doi: 10.1371/journal.pone.0131716. eCollection 2015.

2.

Targeting the urokinase plasminogen activator receptor inhibits ovarian cancer metastasis.

Kenny HA, Leonhardt P, Ladanyi A, Yamada SD, Montag A, Im HK, Jagadeeswaran S, Shaw DE, Mazar AP, Lengyel E.

Clin Cancer Res. 2011 Feb 1;17(3):459-71. doi: 10.1158/1078-0432.CCR-10-2258. Epub 2010 Dec 13.

3.

{beta}3-integrin expression on tumor cells inhibits tumor progression, reduces metastasis, and is associated with a favorable prognosis in patients with ovarian cancer.

Kaur S, Kenny HA, Jagadeeswaran S, Zillhardt MR, Montag AG, Kistner E, Yamada SD, Mitra AK, Lengyel E.

Am J Pathol. 2009 Nov;175(5):2184-96. doi: 10.2353/ajpath.2009.090028. Epub 2009 Oct 1.

4.

Effects of oral contraceptives or a gonadotropin-releasing hormone agonist on ovarian carcinogenesis in genetically engineered mice.

Romero IL, Gordon IO, Jagadeeswaran S, Mui KL, Lee WS, Dinulescu DM, Krausz TN, Kim HH, Gilliam ML, Lengyel E.

Cancer Prev Res (Phila). 2009 Sep;2(9):792-9. doi: 10.1158/1940-6207.CAPR-08-0236. Epub 2009 Sep 8.

5.

Ursodeoxycholic acid suppresses Cox-2 expression in colon cancer: roles of Ras, p38, and CCAAT/enhancer-binding protein.

Khare S, Mustafi R, Cerda S, Yuan W, Jagadeeswaran S, Dougherty U, Tretiakova M, Samarel A, Cohen G, Wang J, Moore C, Wali R, Holgren C, Joseph L, Fichera A, Li YC, Bissonnette M.

Nutr Cancer. 2008;60(3):389-400. doi: 10.1080/01635580701883003.

PMID:
18444174
6.

Epidermal growth factor receptor controls flat dysplastic aberrant crypt foci development and colon cancer progression in the rat azoxymethane model.

Dougherty U, Sehdev A, Cerda S, Mustafi R, Little N, Yuan W, Jagadeeswaran S, Chumsangsri A, Delgado J, Tretiakova M, Joseph L, Hart J, Cohen EE, Aluri L, Fichera A, Bissonnette M.

Clin Cancer Res. 2008 Apr 15;14(8):2253-62. doi: 10.1158/1078-0432.CCR-07-4926.

7.

Loss of E-cadherin promotes ovarian cancer metastasis via alpha 5-integrin, which is a therapeutic target.

Sawada K, Mitra AK, Radjabi AR, Bhaskar V, Kistner EO, Tretiakova M, Jagadeeswaran S, Montag A, Becker A, Kenny HA, Peter ME, Ramakrishnan V, Yamada SD, Lengyel E.

Cancer Res. 2008 Apr 1;68(7):2329-39. doi: 10.1158/0008-5472.CAN-07-5167.

8.

Thrombin induces tumor invasion through the induction and association of matrix metalloproteinase-9 and beta1-integrin on the cell surface.

Radjabi AR, Sawada K, Jagadeeswaran S, Eichbichler A, Kenny HA, Montag A, Bruno K, Lengyel E.

J Biol Chem. 2008 Feb 1;283(5):2822-34. Epub 2007 Nov 29.

9.

Activation of HGF/c-Met pathway contributes to the reactive oxygen species generation and motility of small cell lung cancer cells.

Jagadeeswaran R, Jagadeeswaran S, Bindokas VP, Salgia R.

Am J Physiol Lung Cell Mol Physiol. 2007 Jun;292(6):L1488-94. Epub 2007 Feb 23.

10.

Epidermal growth factor receptor signaling is required for microadenoma formation in the mouse azoxymethane model of colonic carcinogenesis.

Fichera A, Little N, Jagadeeswaran S, Dougherty U, Sehdev A, Mustafi R, Cerda S, Yuan W, Khare S, Tretiakova M, Gong C, Tallerico M, Cohen G, Joseph L, Hart J, Turner JR, Bissonnette M.

Cancer Res. 2007 Jan 15;67(2):827-35.

11.

Epidermal growth factor receptor signaling is up-regulated in human colonic aberrant crypt foci.

Cohen G, Mustafi R, Chumsangsri A, Little N, Nathanson J, Cerda S, Jagadeeswaran S, Dougherty U, Joseph L, Hart J, Yerian L, Tretiakova M, Yuan W, Obara P, Khare S, Sinicrope FA, Fichera A, Boss GR, Carroll R, Bissonnette M.

Cancer Res. 2006 Jun 1;66(11):5656-64.

12.

Functional analysis of c-Met/hepatocyte growth factor pathway in malignant pleural mesothelioma.

Jagadeeswaran R, Ma PC, Seiwert TY, Jagadeeswaran S, Zumba O, Nallasura V, Ahmed S, Filiberti R, Paganuzzi M, Puntoni R, Kratzke RA, Gordon GJ, Sugarbaker DJ, Bueno R, Janamanchi V, Bindokas VP, Kindler HL, Salgia R.

Cancer Res. 2006 Jan 1;66(1):352-61.

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