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Items: 1 to 50 of 70

1.
2.

A potential role of the renin-angiotensin-aldosterone system in epithelial-to-mesenchymal transition-induced renal abnormalities: Mechanisms and therapeutic implications.

Balakumar P, Sambathkumar R, Mahadevan N, Muhsinah AB, Alsayari A, Venkateswaramurthy N, Jagadeesh G.

Pharmacol Res. 2019 Aug;146:104314. doi: 10.1016/j.phrs.2019.104314. Epub 2019 Jun 20. Review.

PMID:
31229564
3.

Correction to: FDA Approval of Angiotensin II for the Treatment of Hypotension in Adults with Distributive Shock.

Senatore F, Jagadeesh G, Rose M, Pillai VC, Hariharan S, Liu Q, McDowell TY, Sapru MK, Southworth MR, Stockbridge N.

Am J Cardiovasc Drugs. 2019 Apr;19(2):227. doi: 10.1007/s40256-019-00335-7.

PMID:
30820768
4.

FDA Approval of Angiotensin II for the Treatment of Hypotension in Adults with Distributive Shock.

Senatore F, Jagadeesh G, Rose M, Pillai VC, Hariharan S, Liu Q, McDowell TY, Sapru MK, Southworth MR, Stockbridge N.

Am J Cardiovasc Drugs. 2019 Feb;19(1):11-20. doi: 10.1007/s40256-018-0297-9. Erratum in: Am J Cardiovasc Drugs. 2019 Apr;19(2):227.

PMID:
30144016
5.

Effect of noise-induced wavelength fluctuation in tunable diode lasers on narrow-linewidth absorption measurements.

Krishna Y, O'Byrne S, Munuswamy K, Jagadeesh G.

Appl Opt. 2018 Jun 10;57(17):4943-4949. doi: 10.1364/AO.57.004943.

PMID:
30118113
6.

Temperature characterization of a radiating gas layer using digital-single-lens-reflex-camera-based two-color ratio pyrometry.

Deep S, Krishna Y, Jagadeesh G.

Appl Opt. 2017 Oct 20;56(30):8492-8500. doi: 10.1364/AO.56.008492.

PMID:
29091629
7.

Renin-angiotensin-aldosterone: An inclusive, an invigorative, an interactive and an interminable system.

Balakumar P, Anand-Srivastava MB, Jagadeesh G.

Pharmacol Res. 2017 Nov;125(Pt A):1-3. doi: 10.1016/j.phrs.2017.07.003. Epub 2017 Jul 12. No abstract available.

PMID:
28711403
8.

Regulatory Forum Review*: Utility of in Vitro Secondary Pharmacology Data to Assess Risk of Drug-induced Valvular Heart Disease in Humans: Regulatory Considerations.

Papoian T, Jagadeesh G, Saulnier M, Simpson N, Ravindran A, Yang B, Laniyonu AA, Khan I, Szarfman A.

Toxicol Pathol. 2017 Apr;45(3):381-388. doi: 10.1177/0192623317690609. Epub 2017 Jan 1. Review.

PMID:
28421966
9.

Clinical efficacy of gene-modified stem cells in adenosine deaminase-deficient immunodeficiency.

Shaw KL, Garabedian E, Mishra S, Barman P, Davila A, Carbonaro D, Shupien S, Silvin C, Geiger S, Nowicki B, Smogorzewska EM, Brown B, Wang X, de Oliveira S, Choi Y, Ikeda A, Terrazas D, Fu PY, Yu A, Fernandez BC, Cooper AR, Engel B, Podsakoff G, Balamurugan A, Anderson S, Muul L, Jagadeesh GJ, Kapoor N, Tse J, Moore TB, Purdy K, Rishi R, Mohan K, Skoda-Smith S, Buchbinder D, Abraham RS, Scharenberg A, Yang OO, Cornetta K, Gjertson D, Hershfield M, Sokolic R, Candotti F, Kohn DB.

J Clin Invest. 2017 May 1;127(5):1689-1699. doi: 10.1172/JCI90367. Epub 2017 Mar 27.

10.
11.

Prevalence and prevention of cardiovascular disease and diabetes mellitus.

Balakumar P, Maung-U K, Jagadeesh G.

Pharmacol Res. 2016 Nov;113(Pt A):600-609. doi: 10.1016/j.phrs.2016.09.040. Epub 2016 Sep 30. Review.

PMID:
27697647
12.

Development of a novel miniature detonation-driven shock tube assembly that uses in situ generated oxyhydrogen mixture.

Janardhanraj S, Jagadeesh G.

Rev Sci Instrum. 2016 Aug;87(8):085114. doi: 10.1063/1.4960961.

PMID:
27587167
13.

Synthetic catecholamine triggers β1-adrenergic receptor activation and stimulates cardiotoxicity via oxidative stress mediated apoptotic cell death in rats: Abrogating action of thymol.

Meeran MF, Jagadeesh GS, Selvaraj P.

Chem Biol Interact. 2016 May 5;251:17-25. doi: 10.1016/j.cbi.2016.03.017. Epub 2016 Mar 18.

PMID:
26996544
14.

Protective Effects of 7-Hydroxycoumarin on Dyslipidemia and Cardiac Hypertrophy in Isoproterenol-Induced Myocardial Infarction in Rats.

Jagadeesh GS, Nagoor Meeran MF, Selvaraj P.

J Biochem Mol Toxicol. 2016 Mar;30(3):120-7. doi: 10.1002/jbt.21770. Epub 2015 Oct 13.

PMID:
26995004
15.

Activation of β1-adrenoceptor triggers oxidative stress mediated myocardial membrane destabilization in isoproterenol induced myocardial infarcted rats: 7-hydroxycoumarin and its counter action.

Jagadeesh GS, Nagoor Meeran MF, Selvaraj P.

Eur J Pharmacol. 2016 Apr 15;777:70-7. doi: 10.1016/j.ejphar.2016.02.063. Epub 2016 Feb 27.

PMID:
26930228
16.

Thymol, a dietary monoterpene phenol abrogates mitochondrial dysfunction in β-adrenergic agonist induced myocardial infarcted rats by inhibiting oxidative stress.

Nagoor Meeran MF, Jagadeesh GS, Selvaraj P.

Chem Biol Interact. 2016 Jan 25;244:159-68. doi: 10.1016/j.cbi.2015.12.006. Epub 2015 Dec 22.

PMID:
26721194
17.

Secondary pharmacology data to assess potential off-target activity of new drugs: a regulatory perspective.

Papoian T, Chiu HJ, Elayan I, Jagadeesh G, Khan I, Laniyonu AA, Li CX, Saulnier M, Simpson N, Yang B.

Nat Rev Drug Discov. 2015 Apr;14(4):294. doi: 10.1038/nrd3845-c1. Epub 2015 Mar 20. No abstract available.

PMID:
25792260
18.

Thymol attenuates inflammation in isoproterenol induced myocardial infarcted rats by inhibiting the release of lysosomal enzymes and downregulating the expressions of proinflammatory cytokines.

Nagoor Meeran MF, Jagadeesh GS, Selvaraj P.

Eur J Pharmacol. 2015 May 5;754:153-61. doi: 10.1016/j.ejphar.2015.02.028. Epub 2015 Feb 25.

PMID:
25724787
19.

Structural determinants for binding, activation, and functional selectivity of the angiotensin AT1 receptor.

Balakumar P, Jagadeesh G.

J Mol Endocrinol. 2014 Oct;53(2):R71-92. doi: 10.1530/JME-14-0125. Epub 2014 Jul 10. Review.

PMID:
25013233
20.

A century old renin-angiotensin system still grows with endless possibilities: AT1 receptor signaling cascades in cardiovascular physiopathology.

Balakumar P, Jagadeesh G.

Cell Signal. 2014 Oct;26(10):2147-60. doi: 10.1016/j.cellsig.2014.06.011. Epub 2014 Jul 5. Review.

PMID:
25007996
22.

Gene therapy for adenosine deaminase-deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans.

Candotti F, Shaw KL, Muul L, Carbonaro D, Sokolic R, Choi C, Schurman SH, Garabedian E, Kesserwan C, Jagadeesh GJ, Fu PY, Gschweng E, Cooper A, Tisdale JF, Weinberg KI, Crooks GM, Kapoor N, Shah A, Abdel-Azim H, Yu XJ, Smogorzewska M, Wayne AS, Rosenblatt HM, Davis CM, Hanson C, Rishi RG, Wang X, Gjertson D, Yang OO, Balamurugan A, Bauer G, Ireland JA, Engel BC, Podsakoff GM, Hershfield MS, Blaese RM, Parkman R, Kohn DB.

Blood. 2012 Nov 1;120(18):3635-46. doi: 10.1182/blood-2012-02-400937. Epub 2012 Sep 11.

23.

Comment on "Physical methods for genetic plant transformation" by Rivera et al.

Nataraja KN, Jagadeesh G.

Phys Life Rev. 2012 Sep;9(3):350-1; discussion 352. doi: 10.1016/j.plrev.2012.07.006. Epub 2012 Jul 20. No abstract available.

PMID:
22840471
24.

Development of micro-shock wave assisted dry particle and fluid jet delivery system.

Rakesh SG, Gnanadhas DP, Allam US, Nataraja KN, Barhai PK, Jagadeesh G, Chakravortty D.

Appl Microbiol Biotechnol. 2012 Nov;96(3):647-62. doi: 10.1007/s00253-012-4196-8. Epub 2012 Jul 5.

PMID:
22763845
25.

The basic concepts of scientific research and scientific communication.

Balakumar P, Jagadeesh G.

J Pharmacol Pharmacother. 2012 Apr;3(2):178-82. doi: 10.4103/0976-500X.95522. No abstract available.

26.

How well do aliskiren's purported mechanisms track its effects on cardiovascular and renal disorders?

Jagadeesh G, Balakumar P, Stockbridge N.

Cell Signal. 2012 Aug;24(8):1583-91. doi: 10.1016/j.cellsig.2012.04.003. Epub 2012 Apr 13. Review.

PMID:
22522051
27.

Foamy virus vector-mediated gene correction of a mouse model of Wiskott-Aldrich syndrome.

Uchiyama T, Adriani M, Jagadeesh GJ, Paine A, Candotti F.

Mol Ther. 2012 Jun;20(6):1270-9. doi: 10.1038/mt.2011.282. Epub 2012 Jan 3.

28.

PPAR ligands and cardiovascular disorders: friend or foe.

Balakumar P, Jagadeesh G.

Curr Mol Pharmacol. 2012 Jun;5(2):219-23. No abstract available.

PMID:
22122451
29.

Bacterial transformation using micro-shock waves.

Divya Prakash G, Anish RV, Jagadeesh G, Chakravortty D.

Anal Biochem. 2011 Dec 15;419(2):292-301. doi: 10.1016/j.ab.2011.08.038. Epub 2011 Aug 27.

PMID:
21939633
30.

Silver nanoparticle synthesis: novel route for laser triggering of polyelectrolyte capsules.

Anandhakumar S, Vijayalakshmi SP, Jagadeesh G, Raichur AM.

ACS Appl Mater Interfaces. 2011 Sep;3(9):3419-24. doi: 10.1021/am200651t. Epub 2011 Sep 2.

PMID:
21861501
31.

Potential cross-talk between (pro)renin receptors and Wnt/frizzled receptors in cardiovascular and renal disorders.

Balakumar P, Jagadeesh G.

Hypertens Res. 2011 Nov;34(11):1161-70. doi: 10.1038/hr.2011.113. Epub 2011 Jul 28. Review.

PMID:
21796133
32.

Needleless vaccine delivery using micro-shock waves.

Jagadeesh G, Prakash GD, Rakesh SG, Allam US, Krishna MG, Eswarappa SM, Chakravortty D.

Clin Vaccine Immunol. 2011 Apr;18(4):539-45. doi: 10.1128/CVI.00494-10. Epub 2011 Feb 9.

34.

Multifarious molecular signaling cascades of cardiac hypertrophy: can the muddy waters be cleared?

Balakumar P, Jagadeesh G.

Pharmacol Res. 2010 Nov;62(5):365-83. doi: 10.1016/j.phrs.2010.07.003. Epub 2010 Jul 17. Review.

PMID:
20643208
35.

Interactions between conserved residues in transmembrane helices 2 and 7 during angiotensin AT1 receptor activation.

Nikiforovich GV, Zhang M, Yang Q, Jagadeesh G, Chen HC, Hunyady L, Marshall GR, Catt KJ.

Chem Biol Drug Des. 2006 Nov;68(5):239-49.

PMID:
17177883
36.

Multiple patients with revertant mosaicism in a single Wiskott-Aldrich syndrome family.

Wada T, Schurman SH, Jagadeesh GJ, Garabedian EK, Nelson DL, Candotti F.

Blood. 2004 Sep 1;104(5):1270-2. Epub 2004 May 13.

37.

Structural determinants of agonist-induced signaling and regulation of the angiotensin AT1 receptor.

Hunyady L, Gáborik Z, Shah BH, Jagadeesh G, Clark AJ, Catt KJ.

Mol Cell Endocrinol. 2004 Mar 31;217(1-2):89-100.

PMID:
15134806
38.

The role of a conserved region of the second intracellular loop in AT1 angiotensin receptor activation and signaling.

Gáborik Z, Jagadeesh G, Zhang M, Spät A, Catt KJ, Hunyady L.

Endocrinology. 2003 Jun;144(6):2220-8.

PMID:
12746278
39.

Persistence and expression of the adenosine deaminase gene for 12 years and immune reaction to gene transfer components: long-term results of the first clinical gene therapy trial.

Muul LM, Tuschong LM, Soenen SL, Jagadeesh GJ, Ramsey WJ, Long Z, Carter CS, Garabedian EK, Alleyne M, Brown M, Bernstein W, Schurman SH, Fleisher TA, Leitman SF, Dunbar CE, Blaese RM, Candotti F.

Blood. 2003 Apr 1;101(7):2563-9. Epub 2002 Nov 27.

40.

Retrovirus-mediated WASP gene transfer corrects Wiskott-Aldrich syndrome T-cell dysfunction.

Wada T, Jagadeesh GJ, Nelson DL, Candotti F.

Hum Gene Ther. 2002 Jun 10;13(9):1039-46.

PMID:
12067437
41.

Unexpected and variable phenotypes in a family with JAK3 deficiency.

Frucht DM, Gadina M, Jagadeesh GJ, Aksentijevich I, Takada K, Bleesing JJ, Nelson J, Muul LM, Perham G, Morgan G, Gerritsen EJ, Schumacher RF, Mella P, Veys PA, Fleisher TA, Kaminski ER, Notarangelo LD, O'Shea JJ, Candotti F.

Genes Immun. 2001 Dec;2(8):422-32.

42.

Stressing-out DNA? The contribution of serine-phosphodiester interactions in catalysis by uracil DNA glycosylase.

Werner RM, Jiang YL, Gordley RG, Jagadeesh GJ, Ladner JE, Xiao G, Tordova M, Gilliland GL, Stivers JT.

Biochemistry. 2000 Oct 17;39(41):12585-94.

PMID:
11027138
43.

Stereochemical outcome and kinetic effects of Rp- and Sp-phosphorothioate substitutions at the cleavage site of vaccinia type I DNA topoisomerase.

Stivers JT, Jagadeesh GJ, Nawrot B, Stec WJ, Shuman S.

Biochemistry. 2000 May 9;39(18):5561-72.

PMID:
10820030
44.

N-linked glycosylation is required for optimal AT1a angiotensin receptor expression in COS-7 cells.

Jayadev S, Smith RD, Jagadeesh G, Baukal AJ, Hunyady L, Catt KJ.

Endocrinology. 1999 May;140(5):2010-7.

PMID:
10218949
45.

Angiotensin II receptors-antagonists, molecular biology, and signal transduction.

Jagadeesh G.

Indian J Exp Biol. 1998 Dec;36(12):1171-94. Review.

PMID:
10093499
46.

Dependence of AT1 angiotensin receptor function on adjacent asparagine residues in the seventh transmembrane helix.

Hunyady L, Ji H, Jagadeesh G, Zhang M, Gáborik Z, Mihalik B, Catt KJ.

Mol Pharmacol. 1998 Aug;54(2):427-34.

PMID:
9687585
47.

Requirement of membrane-proximal amino acids in the carboxyl-terminal tail for expression of the rat AT1a angiotensin receptor.

Gáborik Z, Mihalik B, Jayadev S, Jagadeesh G, Catt KJ, Hunyady L.

FEBS Lett. 1998 May 29;428(3):147-51.

48.

Development of improved adenosine deaminase retroviral vectors.

Onodera M, Nelson DM, Yachie A, Jagadeesh GJ, Bunnell BA, Morgan RA, Blaese RM.

J Virol. 1998 Mar;72(3):1769-74.

49.

Dependence of agonist activation on a conserved apolar residue in the third intracellular loop of the AT1 angiotensin receptor.

Hunyady L, Zhang M, Jagadeesh G, Bor M, Balla T, Catt KJ.

Proc Natl Acad Sci U S A. 1996 Sep 17;93(19):10040-5.

50.

Importance of monitoring calcium & calcium related properties in carrier detection for Duchenne muscular dystrophy.

Jagadeesh G, Shailaja B, Moses L, Kumari CK, Anjaneyulu A, Anandaraj MP.

Indian J Med Res. 1994 Jun;99:283-8.

PMID:
8088891

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