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Items: 1 to 50 of 126

1.

Antibody cross-reactivity accounts for widespread appearance of m1A in 5'UTRs.

Grozhik AV, Olarerin-George AO, Sindelar M, Li X, Gross SS, Jaffrey SR.

Nat Commun. 2019 Nov 12;10(1):5126. doi: 10.1038/s41467-019-13146-w.

2.

A Fluorogenic RNA-Based Sensor Activated by Metabolite-Induced RNA Dimerization.

Kim H, Jaffrey SR.

Cell Chem Biol. 2019 Oct 16. pii: S2451-9456(19)30318-6. doi: 10.1016/j.chembiol.2019.09.013. [Epub ahead of print]

PMID:
31631009
3.

Reading, writing and erasing mRNA methylation.

Zaccara S, Ries RJ, Jaffrey SR.

Nat Rev Mol Cell Biol. 2019 Oct;20(10):608-624. doi: 10.1038/s41580-019-0168-5. Epub 2019 Sep 13. Review.

PMID:
31520073
4.

Quantifying the RNA cap epitranscriptome reveals novel caps in cellular and viral RNA.

Wang J, Alvin Chew BL, Lai Y, Dong H, Xu L, Balamkundu S, Cai WM, Cui L, Liu CF, Fu XY, Lin Z, Shi PY, Lu TK, Luo D, Jaffrey SR, Dedon PC.

Nucleic Acids Res. 2019 Nov 18;47(20):e130. doi: 10.1093/nar/gkz751.

5.

Live imaging of mRNA using RNA-stabilized fluorogenic proteins.

Wu J, Zaccara S, Khuperkar D, Kim H, Tanenbaum ME, Jaffrey SR.

Nat Methods. 2019 Sep;16(9):862-865. doi: 10.1038/s41592-019-0531-7. Epub 2019 Aug 30.

PMID:
31471614
6.

RIBOTACs: Small Molecules Target RNA for Degradation.

Dey SK, Jaffrey SR.

Cell Chem Biol. 2019 Aug 15;26(8):1047-1049. doi: 10.1016/j.chembiol.2019.07.015.

PMID:
31419417
7.

m6A RNA Methylation Maintains Hematopoietic Stem Cell Identity and Symmetric Commitment.

Cheng Y, Luo H, Izzo F, Pickering BF, Nguyen D, Myers R, Schurer A, Gourkanti S, Brüning JC, Vu LP, Jaffrey SR, Landau DA, Kharas MG.

Cell Rep. 2019 Aug 13;28(7):1703-1716.e6. doi: 10.1016/j.celrep.2019.07.032.

8.

Synaptogenesis Stimulates a Proteasome-Mediated Ribosome Reduction in Axons.

Costa RO, Martins H, Martins LF, Cwetsch AW, Mele M, Pedro JR, Tomé D, Jeon NL, Cancedda L, Jaffrey SR, Almeida RD.

Cell Rep. 2019 Jul 23;28(4):864-876.e6. doi: 10.1016/j.celrep.2019.06.080.

9.

The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112.

van Tran N, Ernst FGM, Hawley BR, Zorbas C, Ulryck N, Hackert P, Bohnsack KE, Bohnsack MT, Jaffrey SR, Graille M, Lafontaine DLJ.

Nucleic Acids Res. 2019 Sep 5;47(15):7719-7733. doi: 10.1093/nar/gkz619.

10.

m6A enhances the phase separation potential of mRNA.

Ries RJ, Zaccara S, Klein P, Olarerin-George A, Namkoong S, Pickering BF, Patil DP, Kwak H, Lee JH, Jaffrey SR.

Nature. 2019 Jul;571(7765):424-428. doi: 10.1038/s41586-019-1374-1. Epub 2019 Jul 10.

PMID:
31292544
11.

Identification of the m6Am Methyltransferase PCIF1 Reveals the Location and Functions of m6Am in the Transcriptome.

Boulias K, Toczydłowska-Socha D, Hawley BR, Liberman N, Takashima K, Zaccara S, Guez T, Vasseur JJ, Debart F, Aravind L, Jaffrey SR, Greer EL.

Mol Cell. 2019 Aug 8;75(3):631-643.e8. doi: 10.1016/j.molcel.2019.06.006. Epub 2019 Jul 3.

PMID:
31279658
12.

Discovering and Mapping the Modified Nucleotides That Comprise the Epitranscriptome of mRNA.

Linder B, Jaffrey SR.

Cold Spring Harb Perspect Biol. 2019 Jun 3;11(6). pii: a032201. doi: 10.1101/cshperspect.a032201. Review.

PMID:
31160350
13.

Highly efficient expression of circular RNA aptamers in cells using autocatalytic transcripts.

Litke JL, Jaffrey SR.

Nat Biotechnol. 2019 Jun;37(6):667-675. doi: 10.1038/s41587-019-0090-6. Epub 2019 Apr 8.

14.

Transcriptome-Wide Mapping of m6 A and m6 Am at Single-Nucleotide Resolution Using miCLIP.

Hawley BR, Jaffrey SR.

Curr Protoc Mol Biol. 2019 Apr;126(1):e88. doi: 10.1002/cpmb.88. Epub 2019 Mar 15.

PMID:
30874375
15.

Spectral Tuning by a Single Nucleotide Controls the Fluorescence Properties of a Fluorogenic Aptamer.

Filonov GS, Song W, Jaffrey SR.

Biochemistry. 2019 Mar 26;58(12):1560-1564. doi: 10.1021/acs.biochem.9b00048. Epub 2019 Mar 11.

PMID:
30838859
16.

FTO controls reversible m6Am RNA methylation during snRNA biogenesis.

Mauer J, Sindelar M, Despic V, Guez T, Hawley BR, Vasseur JJ, Rentmeister A, Gross SS, Pellizzoni L, Debart F, Goodarzi H, Jaffrey SR.

Nat Chem Biol. 2019 Apr;15(4):340-347. doi: 10.1038/s41589-019-0231-8. Epub 2019 Feb 18.

PMID:
30778204
17.

Detection of Low-Abundance Metabolites in Live Cells Using an RNA Integrator.

You M, Litke JL, Wu R, Jaffrey SR.

Cell Chem Biol. 2019 Apr 18;26(4):471-481.e3. doi: 10.1016/j.chembiol.2019.01.005. Epub 2019 Feb 14.

PMID:
30773480
18.

Combining Chemical Synthesis and Enzymatic Methylation to Access Short RNAs with Various 5' Caps.

Muthmann N, Guez T, Vasseur JJ, Jaffrey SR, Debart F, Rentmeister A.

Chembiochem. 2019 Jul 1;20(13):1693-1700. doi: 10.1002/cbic.201900037. Epub 2019 May 27.

PMID:
30768827
19.

Nonsense-mediated RNA decay in the brain: emerging modulator of neural development and disease.

Jaffrey SR, Wilkinson MF.

Nat Rev Neurosci. 2018 Dec;19(12):715-728. doi: 10.1038/s41583-018-0079-z. Review.

20.

FTO, m6 Am , and the hypothesis of reversible epitranscriptomic mRNA modifications.

Mauer J, Jaffrey SR.

FEBS Lett. 2018 Jun;592(12):2012-2022. doi: 10.1002/1873-3468.13092. Epub 2018 May 24. Review.

21.

Distinguishing RNA modifications from noise in epitranscriptome maps.

Grozhik AV, Jaffrey SR.

Nat Chem Biol. 2018 Feb 14;14(3):215-225. doi: 10.1038/nchembio.2546.

PMID:
29443978
22.

A Staufen1-mediated decay pathway influences the local transcriptome in axons.

Kim JY, Deglincerti A, Jaffrey SR.

Translation (Austin). 2017 Dec 12;5(2):e1414016. doi: 10.1080/21690731.2017.1414016. eCollection 2017.

23.

RNA-Based Fluorescent Biosensors for Detecting Metabolites in vitro and in Living Cells.

Jaffrey SR.

Adv Pharmacol. 2018;82:187-203. doi: 10.1016/bs.apha.2017.09.005. Epub 2017 Oct 25. Review.

PMID:
29413520
24.

Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1.

Wu B, Su S, Patil DP, Liu H, Gan J, Jaffrey SR, Ma J.

Nat Commun. 2018 Jan 29;9(1):420. doi: 10.1038/s41467-017-02770-z.

25.

Reading m6A in the Transcriptome: m6A-Binding Proteins.

Patil DP, Pickering BF, Jaffrey SR.

Trends Cell Biol. 2018 Feb;28(2):113-127. doi: 10.1016/j.tcb.2017.10.001. Epub 2017 Nov 2. Review.

26.

Epitranscriptomics: Shrinking maps of RNA modifications.

Grozhik AV, Jaffrey SR.

Nature. 2017 Nov 9;551(7679):174-176. doi: 10.1038/nature24156. Epub 2017 Oct 25. No abstract available.

PMID:
29072301
27.

Defining the location of promoter-associated R-loops at near-nucleotide resolution using bisDRIP-seq.

Dumelie JG, Jaffrey SR.

Elife. 2017 Oct 26;6. pii: e28306. doi: 10.7554/eLife.28306.

28.

A homodimer interface without base pairs in an RNA mimic of red fluorescent protein.

Warner KD, Sjekloća L, Song W, Filonov GS, Jaffrey SR, Ferré-D'Amaré AR.

Nat Chem Biol. 2017 Nov;13(11):1195-1201. doi: 10.1038/nchembio.2475. Epub 2017 Sep 25.

29.

Imaging RNA polymerase III transcription using a photostable RNA-fluorophore complex.

Song W, Filonov GS, Kim H, Hirsch M, Li X, Moon JD, Jaffrey SR.

Nat Chem Biol. 2017 Nov;13(11):1187-1194. doi: 10.1038/nchembio.2477. Epub 2017 Sep 25.

30.

The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells.

Vu LP, Pickering BF, Cheng Y, Zaccara S, Nguyen D, Minuesa G, Chou T, Chow A, Saletore Y, MacKay M, Schulman J, Famulare C, Patel M, Klimek VM, Garrett-Bakelman FE, Melnick A, Carroll M, Mason CE, Jaffrey SR, Kharas MG.

Nat Med. 2017 Nov;23(11):1369-1376. doi: 10.1038/nm.4416. Epub 2017 Sep 18.

31.

Rethinking m6A Readers, Writers, and Erasers.

Meyer KD, Jaffrey SR.

Annu Rev Cell Dev Biol. 2017 Oct 6;33:319-342. doi: 10.1146/annurev-cellbio-100616-060758. Epub 2017 Jul 31. Review.

32.

The m6A pathway facilitates sex determination in Drosophila.

Kan L, Grozhik AV, Vedanayagam J, Patil DP, Pang N, Lim KS, Huang YC, Joseph B, Lin CJ, Despic V, Guo J, Yan D, Kondo S, Deng WM, Dedon PC, Jaffrey SR, Lai EC.

Nat Commun. 2017 Jul 4;8:15737. doi: 10.1038/ncomms15737.

33.

Mapping m6A at Individual-Nucleotide Resolution Using Crosslinking and Immunoprecipitation (miCLIP).

Grozhik AV, Linder B, Olarerin-George AO, Jaffrey SR.

Methods Mol Biol. 2017;1562:55-78. doi: 10.1007/978-1-4939-6807-7_5.

34.

MetaPlotR: a Perl/R pipeline for plotting metagenes of nucleotide modifications and other transcriptomic sites.

Olarerin-George AO, Jaffrey SR.

Bioinformatics. 2017 May 15;33(10):1563-1564. doi: 10.1093/bioinformatics/btx002.

35.

Emerging links between m6A and misregulated mRNA methylation in cancer.

Jaffrey SR, Kharas MG.

Genome Med. 2017 Jan 12;9(1):2. doi: 10.1186/s13073-016-0395-8.

36.

Photoacid Behaviour in a Fluorinated Green Fluorescent Protein Chromophore: Ultrafast Formation of Anion and Zwitterion States..

Laptenok SP, Conyard J, Page PC, Chan Y, You M, Jaffrey SR, Meech SR.

Chem Sci. 2016;7(9):5747-5752. doi: 10.1039/C6SC02031C. Epub 2016 Jun 6.

37.

Reversible methylation of m6Am in the 5' cap controls mRNA stability.

Mauer J, Luo X, Blanjoie A, Jiao X, Grozhik AV, Patil DP, Linder B, Pickering BF, Vasseur JJ, Chen Q, Gross SS, Elemento O, Debart F, Kiledjian M, Jaffrey SR.

Nature. 2017 Jan 19;541(7637):371-375. doi: 10.1038/nature21022. Epub 2016 Dec 21.

38.

m(6)A RNA methylation promotes XIST-mediated transcriptional repression.

Patil DP, Chen CK, Pickering BF, Chow A, Jackson C, Guttman M, Jaffrey SR.

Nature. 2016 Sep 15;537(7620):369-373. doi: 10.1038/nature19342. Epub 2016 Sep 7.

39.

Tracking translation one mRNA at a time.

Wu J, Jaffrey SR.

Nat Biotechnol. 2016 Jul 12;34(7):723-4. doi: 10.1038/nbt.3632. No abstract available.

PMID:
27404883
40.

Peptide Synthesis on a Next-Generation DNA Sequencing Platform.

Svensen N, Peersen OB, Jaffrey SR.

Chembiochem. 2016 Sep 2;17(17):1628-35. doi: 10.1002/cbic.201600298. Epub 2016 Jul 6.

41.

Nucleic Acid-Based Nanodevices in Biological Imaging.

Chakraborty K, Veetil AT, Jaffrey SR, Krishnan Y.

Annu Rev Biochem. 2016 Jun 2;85:349-73. doi: 10.1146/annurev-biochem-060815-014244. Review.

42.

Small Molecule Recognition and Tools to Study Modulation of r(CGG)(exp) in Fragile X-Associated Tremor Ataxia Syndrome.

Yang WY, He F, Strack RL, Oh SY, Frazer M, Jaffrey SR, Todd PK, Disney MD.

ACS Chem Biol. 2016 Sep 16;11(9):2456-65. doi: 10.1021/acschembio.6b00147. Epub 2016 Jul 11.

43.

Preface.

Filonov GS, Jaffrey SR.

Methods Enzymol. 2016;572:xv-xvi. doi: 10.1016/S0076-6879(16)30101-X. No abstract available.

44.

Developing Fluorogenic Riboswitches for Imaging Metabolite Concentration Dynamics in Bacterial Cells.

Litke JL, You M, Jaffrey SR.

Methods Enzymol. 2016;572:315-33. doi: 10.1016/bs.mie.2016.03.021. Epub 2016 Apr 19.

45.

RNA modifications: what have we learned and where are we headed?

Frye M, Jaffrey SR, Pan T, Rechavi G, Suzuki T.

Nat Rev Genet. 2016 Jun;17(6):365-72. doi: 10.1038/nrg.2016.47. Epub 2016 May 3. Review.

PMID:
27140282
46.

Separating neuronal compartments gives clues as to local effect of ubiquitin conjugates in synaptogenesis.

Kim JY, Jaffrey SR.

J Cell Biol. 2016 Mar 28;212(7):751-3. doi: 10.1083/jcb.201603028.

47.

RNA Imaging with Dimeric Broccoli in Live Bacterial and Mammalian Cells.

Filonov GS, Jaffrey SR.

Curr Protoc Chem Biol. 2016 Mar 16;8(1):1-28. doi: 10.1002/9780470559277.ch150174.

48.

Fluorescent RNA Aptamers as a Tool to Study RNA-Modifying Enzymes.

Svensen N, Jaffrey SR.

Cell Chem Biol. 2016 Mar 17;23(3):415-25. doi: 10.1016/j.chembiol.2015.11.018. Epub 2016 Feb 11.

49.

Expanding the diversity of DNA base modifications with N⁶-methyldeoxyadenosine.

Meyer KD, Jaffrey SR.

Genome Biol. 2016 Jan 13;17:5. doi: 10.1186/s13059-016-0874-7.

50.

5' UTR m(6)A Promotes Cap-Independent Translation.

Meyer KD, Patil DP, Zhou J, Zinoviev A, Skabkin MA, Elemento O, Pestova TV, Qian SB, Jaffrey SR.

Cell. 2015 Nov 5;163(4):999-1010. doi: 10.1016/j.cell.2015.10.012. Epub 2015 Oct 22.

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