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Items: 1 to 50 of 117

1.

Getting in the Flo: My year as a scholar.

Jaffrey S.

J Perioper Pract. 2018 Sep 13:1750458918791122. doi: 10.1177/1750458918791122. [Epub ahead of print]

PMID:
30212285
2.

FTO, m6 Am , and the hypothesis of reversible epitranscriptomic mRNA modifications.

Mauer J, Jaffrey SR.

FEBS Lett. 2018 Jun;592(12):2012-2022. doi: 10.1002/1873-3468.13092. Epub 2018 May 24. Review.

PMID:
29754392
3.

Distinguishing RNA modifications from noise in epitranscriptome maps.

Grozhik AV, Jaffrey SR.

Nat Chem Biol. 2018 Feb 14;14(3):215-225. doi: 10.1038/nchembio.2546.

PMID:
29443978
4.

A Staufen1-mediated decay pathway influences the local transcriptome in axons.

Kim JY, Deglincerti A, Jaffrey SR.

Translation (Austin). 2017 Dec 12;5(2):e1414016. doi: 10.1080/21690731.2017.1414016. eCollection 2017.

PMID:
29416957
5.

RNA-Based Fluorescent Biosensors for Detecting Metabolites in vitro and in Living Cells.

Jaffrey SR.

Adv Pharmacol. 2018;82:187-203. doi: 10.1016/bs.apha.2017.09.005. Epub 2017 Oct 25.

PMID:
29413520
6.

Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1.

Wu B, Su S, Patil DP, Liu H, Gan J, Jaffrey SR, Ma J.

Nat Commun. 2018 Jan 29;9(1):420. doi: 10.1038/s41467-017-02770-z.

7.

Reading m6A in the Transcriptome: m6A-Binding Proteins.

Patil DP, Pickering BF, Jaffrey SR.

Trends Cell Biol. 2018 Feb;28(2):113-127. doi: 10.1016/j.tcb.2017.10.001. Epub 2017 Nov 2. Review.

PMID:
29103884
8.

Epitranscriptomics: Shrinking maps of RNA modifications.

Grozhik AV, Jaffrey SR.

Nature. 2017 Nov 9;551(7679):174-176. doi: 10.1038/nature24156. Epub 2017 Oct 25. No abstract available.

PMID:
29072301
9.

Defining the location of promoter-associated R-loops at near-nucleotide resolution using bisDRIP-seq.

Dumelie JG, Jaffrey SR.

Elife. 2017 Oct 26;6. pii: e28306. doi: 10.7554/eLife.28306.

10.

A homodimer interface without base pairs in an RNA mimic of red fluorescent protein.

Warner KD, Sjekloća L, Song W, Filonov GS, Jaffrey SR, Ferré-D'Amaré AR.

Nat Chem Biol. 2017 Nov;13(11):1195-1201. doi: 10.1038/nchembio.2475. Epub 2017 Sep 25.

11.

Imaging RNA polymerase III transcription using a photostable RNA-fluorophore complex.

Song W, Filonov GS, Kim H, Hirsch M, Li X, Moon JD, Jaffrey SR.

Nat Chem Biol. 2017 Nov;13(11):1187-1194. doi: 10.1038/nchembio.2477. Epub 2017 Sep 25.

12.

The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells.

Vu LP, Pickering BF, Cheng Y, Zaccara S, Nguyen D, Minuesa G, Chou T, Chow A, Saletore Y, MacKay M, Schulman J, Famulare C, Patel M, Klimek VM, Garrett-Bakelman FE, Melnick A, Carroll M, Mason CE, Jaffrey SR, Kharas MG.

Nat Med. 2017 Nov;23(11):1369-1376. doi: 10.1038/nm.4416. Epub 2017 Sep 18.

13.

Rethinking m6A Readers, Writers, and Erasers.

Meyer KD, Jaffrey SR.

Annu Rev Cell Dev Biol. 2017 Oct 6;33:319-342. doi: 10.1146/annurev-cellbio-100616-060758. Epub 2017 Jul 31. Review.

14.

The m6A pathway facilitates sex determination in Drosophila.

Kan L, Grozhik AV, Vedanayagam J, Patil DP, Pang N, Lim KS, Huang YC, Joseph B, Lin CJ, Despic V, Guo J, Yan D, Kondo S, Deng WM, Dedon PC, Jaffrey SR, Lai EC.

Nat Commun. 2017 Jul 4;8:15737. doi: 10.1038/ncomms15737.

15.

Mapping m6A at Individual-Nucleotide Resolution Using Crosslinking and Immunoprecipitation (miCLIP).

Grozhik AV, Linder B, Olarerin-George AO, Jaffrey SR.

Methods Mol Biol. 2017;1562:55-78. doi: 10.1007/978-1-4939-6807-7_5.

16.

MetaPlotR: a Perl/R pipeline for plotting metagenes of nucleotide modifications and other transcriptomic sites.

Olarerin-George AO, Jaffrey SR.

Bioinformatics. 2017 May 15;33(10):1563-1564. doi: 10.1093/bioinformatics/btx002.

17.

Emerging links between m6A and misregulated mRNA methylation in cancer.

Jaffrey SR, Kharas MG.

Genome Med. 2017 Jan 12;9(1):2. doi: 10.1186/s13073-016-0395-8.

18.

Photoacid Behaviour in a Fluorinated Green Fluorescent Protein Chromophore: Ultrafast Formation of Anion and Zwitterion States..

Laptenok SP, Conyard J, Page PC, Chan Y, You M, Jaffrey SR, Meech SR.

Chem Sci. 2016;7(9):5747-5752. doi: 10.1039/C6SC02031C. Epub 2016 Jun 6.

19.

Reversible methylation of m6Am in the 5' cap controls mRNA stability.

Mauer J, Luo X, Blanjoie A, Jiao X, Grozhik AV, Patil DP, Linder B, Pickering BF, Vasseur JJ, Chen Q, Gross SS, Elemento O, Debart F, Kiledjian M, Jaffrey SR.

Nature. 2017 Jan 19;541(7637):371-375. doi: 10.1038/nature21022. Epub 2016 Dec 21.

20.

m(6)A RNA methylation promotes XIST-mediated transcriptional repression.

Patil DP, Chen CK, Pickering BF, Chow A, Jackson C, Guttman M, Jaffrey SR.

Nature. 2016 Sep 15;537(7620):369-373. doi: 10.1038/nature19342. Epub 2016 Sep 7.

21.

Tracking translation one mRNA at a time.

Wu J, Jaffrey SR.

Nat Biotechnol. 2016 Jul 12;34(7):723-4. doi: 10.1038/nbt.3632. No abstract available.

PMID:
27404883
22.

Peptide Synthesis on a Next-Generation DNA Sequencing Platform.

Svensen N, Peersen OB, Jaffrey SR.

Chembiochem. 2016 Sep 2;17(17):1628-35. doi: 10.1002/cbic.201600298. Epub 2016 Jul 6.

23.

Nucleic Acid-Based Nanodevices in Biological Imaging.

Chakraborty K, Veetil AT, Jaffrey SR, Krishnan Y.

Annu Rev Biochem. 2016 Jun 2;85:349-73. doi: 10.1146/annurev-biochem-060815-014244. Review.

24.

Small Molecule Recognition and Tools to Study Modulation of r(CGG)(exp) in Fragile X-Associated Tremor Ataxia Syndrome.

Yang WY, He F, Strack RL, Oh SY, Frazer M, Jaffrey SR, Todd PK, Disney MD.

ACS Chem Biol. 2016 Sep 16;11(9):2456-65. doi: 10.1021/acschembio.6b00147. Epub 2016 Jul 11.

25.

Preface.

Filonov GS, Jaffrey SR.

Methods Enzymol. 2016;572:xv-xvi. doi: 10.1016/S0076-6879(16)30101-X. No abstract available.

26.

Developing Fluorogenic Riboswitches for Imaging Metabolite Concentration Dynamics in Bacterial Cells.

Litke JL, You M, Jaffrey SR.

Methods Enzymol. 2016;572:315-33. doi: 10.1016/bs.mie.2016.03.021. Epub 2016 Apr 19.

27.

RNA modifications: what have we learned and where are we headed?

Frye M, Jaffrey SR, Pan T, Rechavi G, Suzuki T.

Nat Rev Genet. 2016 Jun;17(6):365-72. doi: 10.1038/nrg.2016.47. Epub 2016 May 3. Review.

PMID:
27140282
28.

Separating neuronal compartments gives clues as to local effect of ubiquitin conjugates in synaptogenesis.

Kim JY, Jaffrey SR.

J Cell Biol. 2016 Mar 28;212(7):751-3. doi: 10.1083/jcb.201603028.

29.

RNA Imaging with Dimeric Broccoli in Live Bacterial and Mammalian Cells.

Filonov GS, Jaffrey SR.

Curr Protoc Chem Biol. 2016 Mar 16;8(1):1-28. doi: 10.1002/9780470559277.ch150174.

30.

Fluorescent RNA Aptamers as a Tool to Study RNA-Modifying Enzymes.

Svensen N, Jaffrey SR.

Cell Chem Biol. 2016 Mar 17;23(3):415-25. doi: 10.1016/j.chembiol.2015.11.018. Epub 2016 Feb 11.

31.

Expanding the diversity of DNA base modifications with N⁶-methyldeoxyadenosine.

Meyer KD, Jaffrey SR.

Genome Biol. 2016 Jan 13;17:5. doi: 10.1186/s13059-016-0874-7.

32.

5' UTR m(6)A Promotes Cap-Independent Translation.

Meyer KD, Patil DP, Zhou J, Zinoviev A, Skabkin MA, Elemento O, Pestova TV, Qian SB, Jaffrey SR.

Cell. 2015 Nov 5;163(4):999-1010. doi: 10.1016/j.cell.2015.10.012. Epub 2015 Oct 22.

33.

Dynamic m(6)A mRNA methylation directs translational control of heat shock response.

Zhou J, Wan J, Gao X, Zhang X, Jaffrey SR, Qian SB.

Nature. 2015 Oct 22;526(7574):591-4. doi: 10.1038/nature15377. Epub 2015 Oct 12.

34.

Editorial overview: Molecular imaging: Cellular imaging approaches.

Miyawaki A, Jaffrey SR.

Curr Opin Chem Biol. 2015 Aug;27:v-vi. doi: 10.1016/j.cbpa.2015.07.004. Epub 2015 Jul 31. No abstract available.

PMID:
26238588
35.

A novel effect of thalidomide and its analogs: suppression of cereblon ubiquitination enhances ubiquitin ligase function.

Liu Y, Huang X, He X, Zhou Y, Jiang X, Chen-Kiang S, Jaffrey SR, Xu G.

FASEB J. 2015 Dec;29(12):4829-39. doi: 10.1096/fj.15-274050. Epub 2015 Jul 31.

36.

Metazoan tRNA introns generate stable circular RNAs in vivo.

Lu Z, Filonov GS, Noto JJ, Schmidt CA, Hatkevich TL, Wen Y, Jaffrey SR, Matera AG.

RNA. 2015 Sep;21(9):1554-65. doi: 10.1261/rna.052944.115. Epub 2015 Jul 20.

37.

Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome.

Linder B, Grozhik AV, Olarerin-George AO, Meydan C, Mason CE, Jaffrey SR.

Nat Methods. 2015 Aug;12(8):767-72. doi: 10.1038/nmeth.3453. Epub 2015 Jun 29.

38.

Structure and Mechanism of RNA Mimics of Green Fluorescent Protein.

You M, Jaffrey SR.

Annu Rev Biophys. 2015;44:187-206. doi: 10.1146/annurev-biophys-060414-033954. Review.

PMID:
26098513
39.

In-gel imaging of RNA processing using broccoli reveals optimal aptamer expression strategies.

Filonov GS, Kam CW, Song W, Jaffrey SR.

Chem Biol. 2015 May 21;22(5):649-60. doi: 10.1016/j.chembiol.2015.04.018.

40.

Imaging metabolite dynamics in living cells using a Spinach-based riboswitch.

You M, Litke JL, Jaffrey SR.

Proc Natl Acad Sci U S A. 2015 May 26;112(21):E2756-65. doi: 10.1073/pnas.1504354112. Epub 2015 May 11.

41.

Coupled local translation and degradation regulate growth cone collapse.

Deglincerti A, Liu Y, Colak D, Hengst U, Xu G, Jaffrey SR.

Nat Commun. 2015 Apr 22;6:6888. doi: 10.1038/ncomms7888.

42.

Designing optogenetically controlled RNA for regulating biological systems.

You M, Jaffrey SR.

Ann N Y Acad Sci. 2015 Sep;1352:13-9. doi: 10.1111/nyas.12660. Epub 2015 Mar 10. Review.

43.

Live-cell imaging of mammalian RNAs with Spinach2.

Strack RL, Jaffrey SR.

Methods Enzymol. 2015;550:129-46. doi: 10.1016/bs.mie.2014.10.044. Epub 2015 Jan 6.

44.

Activation of SIRT3 by the NAD⁺ precursor nicotinamide riboside protects from noise-induced hearing loss.

Brown KD, Maqsood S, Huang JY, Pan Y, Harkcom W, Li W, Sauve A, Verdin E, Jaffrey SR.

Cell Metab. 2014 Dec 2;20(6):1059-68. doi: 10.1016/j.cmet.2014.11.003.

45.

RNA editing, epitranscriptomics, and processing in cancer progression.

Witkin KL, Hanlon SE, Strasburger JA, Coffin JM, Jaffrey SR, Howcroft TK, Dedon PC, Steitz JA, Daschner PJ, Read-Connole E.

Cancer Biol Ther. 2015;16(1):21-7. doi: 10.4161/15384047.2014.987555.

46.

An expanding universe of mRNA modifications.

Jaffrey SR.

Nat Struct Mol Biol. 2014 Nov;21(11):945-6. doi: 10.1038/nsmb.2911. No abstract available.

47.

Broccoli: rapid selection of an RNA mimic of green fluorescent protein by fluorescence-based selection and directed evolution.

Filonov GS, Moon JD, Svensen N, Jaffrey SR.

J Am Chem Soc. 2014 Nov 19;136(46):16299-308. doi: 10.1021/ja508478x. Epub 2014 Nov 5.

48.

Structural basis for activity of highly efficient RNA mimics of green fluorescent protein.

Warner KD, Chen MC, Song W, Strack RL, Thorn A, Jaffrey SR, Ferré-D'Amaré AR.

Nat Struct Mol Biol. 2014 Aug;21(8):658-63. doi: 10.1038/nsmb.2865. Epub 2014 Jul 15.

49.

Profiling lysine ubiquitination by selective enrichment of ubiquitin remnant-containing peptides.

Xu G, Deglincerti A, Paige JS, Jaffrey SR.

Methods Mol Biol. 2014;1174:57-71. doi: 10.1007/978-1-4939-0944-5_4.

PMID:
24947374
50.

NAD+ and SIRT3 control microtubule dynamics and reduce susceptibility to antimicrotubule agents.

Harkcom WT, Ghosh AK, Sung MS, Matov A, Brown KD, Giannakakou P, Jaffrey SR.

Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):E2443-52. doi: 10.1073/pnas.1404269111. Epub 2014 Jun 2.

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