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Items: 46


Hepatic HAX-1 inactivation prevents metabolic diseases by enhancing mitochondrial activity and bile salt export.

Alogaili F, Chinnarasu S, Jaeschke A, Kranias EG, Hui DY.

J Biol Chem. 2020 Feb 20. pii: jbc.RA119.012361. doi: 10.1074/jbc.RA119.012361. [Epub ahead of print]


Assessing the exposure of forest habitat types to projected climate change-Implications for Bavarian protected areas.

Steinacker C, Beierkuhnlein C, Jaeschke A.

Ecol Evol. 2019 Nov 28;9(24):14417-14429. doi: 10.1002/ece3.5877. eCollection 2019 Dec.


ApoER2 (Apolipoprotein E Receptor-2) Deficiency Accelerates Smooth Muscle Cell Senescence via Cytokinesis Impairment and Promotes Fibrotic Neointima After Vascular Injury.

Komaravolu RK, Waltmann MD, Konaniah E, Jaeschke A, Hui DY.

Arterioscler Thromb Vasc Biol. 2019 Oct;39(10):2132-2144. doi: 10.1161/ATVBAHA.119.313194. Epub 2019 Aug 15.


Mito-tempo protects against acute liver injury but induces limited secondary apoptosis during the late phase of acetaminophen hepatotoxicity.

Du K, Ramachandran A, Weemhoff JL, Woolbright BL, Jaeschke AH, Chao X, Ding WX, Jaeschke H.

Arch Toxicol. 2019 Jan;93(1):163-178. doi: 10.1007/s00204-018-2331-8. Epub 2018 Oct 15.


Evaluating the risk for Usutu virus circulation in Europe: comparison of environmental niche models and epidemiological models.

Cheng Y, Tjaden NB, Jaeschke A, Lühken R, Ziegler U, Thomas SM, Beierkuhnlein C.

Int J Health Geogr. 2018 Oct 12;17(1):35. doi: 10.1186/s12942-018-0155-7.


Invasion of a Legume Ecosystem Engineer in a Cold Biome Alters Plant Biodiversity.

Vetter VMS, Tjaden NB, Jaeschke A, Buhk C, Wahl V, Wasowicz P, Jentsch A.

Front Plant Sci. 2018 Jun 5;9:715. doi: 10.3389/fpls.2018.00715. eCollection 2018.


Areas with High Hazard Potential for Autochthonous Transmission of Aedes albopictus-Associated Arboviruses in Germany.

Thomas SM, Tjaden NB, Frank C, Jaeschke A, Zipfel L, Wagner-Wiening C, Faber M, Beierkuhnlein C, Stark K.

Int J Environ Res Public Health. 2018 Jun 15;15(6). pii: E1270. doi: 10.3390/ijerph15061270.


Low-density lipoprotein receptor-related protein-1 dysfunction synergizes with dietary cholesterol to accelerate steatohepatitis progression.

Hamlin AN, Chinnarasu S, Ding Y, Xian X, Herz J, Jaeschke A, Hui DY.

J Biol Chem. 2018 Jun 22;293(25):9674-9684. doi: 10.1074/jbc.RA118.001952. Epub 2018 May 11.


A Scoping Review of Health Outcomes Examined in Randomized Controlled Trials Using Guided Imagery.

Giacobbi PR Jr, Stewart J, Chaffee K, Jaeschke AM, Stabler M, Kelley GA.

Prog Prev Med (N Y). 2017 Dec;2(7):e0010. doi: 10.1097/pp9.0000000000000010.


Spatiotemporal and molecular epidemiology of cutaneous leishmaniasis in Libya.

Amro A, Al-Dwibe H, Gashout A, Moskalenko O, Galafin M, Hamarsheh O, Frohme M, Jaeschke A, Schönian G, Kuhls K.

PLoS Negl Trop Dis. 2017 Sep 7;11(9):e0005873. doi: 10.1371/journal.pntd.0005873. eCollection 2017 Sep.


LRP1 Protein Deficiency Exacerbates Palmitate-induced Steatosis and Toxicity in Hepatocytes.

Hamlin AN, Basford JE, Jaeschke A, Hui DY.

J Biol Chem. 2016 Aug 5;291(32):16610-9. doi: 10.1074/jbc.M116.717744. Epub 2016 Jun 17.


Guided Imagery for Arthritis and Other Rheumatic Diseases: A Systematic Review of Randomized Controlled Trials.

Giacobbi PR Jr, Stabler ME, Stewart J, Jaeschke AM, Siebert JL, Kelley GA.

Pain Manag Nurs. 2015 Oct;16(5):792-803. doi: 10.1016/j.pmn.2015.01.003. Epub 2015 Jul 11. Review.


Regulation of Adipose Tissue Inflammation and Insulin Resistance by MAPK Phosphatase 5.

Zhang Y, Nguyen T, Tang P, Kennedy NJ, Jiao H, Zhang M, Reynolds JM, Jaeschke A, Martin-Orozco N, Chung Y, He WM, Wang C, Jia W, Ge B, Davis RJ, Flavell RA, Dong C.

J Biol Chem. 2015 Jun 12;290(24):14875-83. doi: 10.1074/jbc.M115.660969. Epub 2015 Apr 28.


Mixed-lineage kinase 3 deficiency promotes neointima formation through increased activation of the RhoA pathway in vascular smooth muscle cells.

Gadang V, Konaniah E, Hui DY, Jaeschke A.

Arterioscler Thromb Vasc Biol. 2014 Jul;34(7):1429-36. doi: 10.1161/ATVBAHA.114.303439. Epub 2014 May 1.


Biosignatures in chimney structures and sediment from the Loki's Castle low-temperature hydrothermal vent field at the Arctic Mid-Ocean Ridge.

Jaeschke A, Eickmann B, Lang SQ, Bernasconi SM, Strauss H, Früh-Green GL.

Extremophiles. 2014 May;18(3):545-60.


Increased dust deposition in the Pacific Southern Ocean during glacial periods.

Lamy F, Gersonde R, Winckler G, Esper O, Jaeschke A, Kuhn G, Ullermann J, Martinez-Garcia A, Lambert F, Kilian R.

Science. 2014 Jan 24;343(6169):403-7. doi: 10.1126/science.1245424.


The last decade in ecological climate change impact research: where are we now?

Jaeschke A, Bittner T, Jentsch A, Beierkuhnlein C.

Naturwissenschaften. 2014 Jan;101(1):1-9. doi: 10.1007/s00114-013-1132-4. Epub 2014 Jan 4. Review.


Mixed lineage kinase 3 deficient mice are protected against the high fat high carbohydrate diet-induced steatohepatitis.

Ibrahim SH, Gores GJ, Hirsova P, Kirby M, Miles L, Jaeschke A, Kohli R.

Liver Int. 2014 Mar;34(3):427-37. doi: 10.1111/liv.12353. Epub 2013 Nov 20.


Olfactory imprinting is triggered by MHC peptide ligands.

Hinz C, Namekawa I, Behrmann-Godel J, Oppelt C, Jaeschke A, Müller A, Friedrich RW, Gerlach G.

Sci Rep. 2013 Sep 30;3:2800. doi: 10.1038/srep02800. Erratum in: Sci Rep. 2014;4:3385. Namekawa, Ri [corrected to Namekawa, Iori].


MLK3 promotes metabolic dysfunction induced by saturated fatty acid-enriched diet.

Gadang V, Kohli R, Myronovych A, Hui DY, Perez-Tilve D, Jaeschke A.

Am J Physiol Endocrinol Metab. 2013 Aug 15;305(4):E549-56. doi: 10.1152/ajpendo.00197.2013. Epub 2013 Jul 16.


Biotic interactions in the face of climate change: a comparison of three modelling approaches.

Jaeschke A, Bittner T, Jentsch A, Reineking B, Schlumprecht H, Beierkuhnlein C.

PLoS One. 2012;7(12):e51472. doi: 10.1371/journal.pone.0051472. Epub 2012 Dec 6.


Microbial diversity of Loki's Castle black smokers at the Arctic Mid-Ocean Ridge.

Jaeschke A, Jørgensen SL, Bernasconi SM, Pedersen RB, Thorseth IH, Früh-Green GL.

Geobiology. 2012 Nov;10(6):548-61. doi: 10.1111/gbi.12009. Epub 2012 Sep 25.


Synergistic effect of defined artificial extracellular matrices and pulsed electric fields on osteogenic differentiation of human MSCs.

Hess R, Jaeschke A, Neubert H, Hintze V, Moeller S, Schnabelrauch M, Wiesmann HP, Hart DA, Scharnweber D.

Biomaterials. 2012 Dec;33(35):8975-85. doi: 10.1016/j.biomaterials.2012.08.056. Epub 2012 Sep 17.


Critical role for mixed-lineage kinase 3 in acetaminophen-induced hepatotoxicity.

Sharma M, Gadang V, Jaeschke A.

Mol Pharmacol. 2012 Nov;82(5):1001-7. doi: 10.1124/mol.112.079863. Epub 2012 Aug 23.


Apolipoprotein E4 impairs macrophage efferocytosis and potentiates apoptosis by accelerating endoplasmic reticulum stress.

Cash JG, Kuhel DG, Basford JE, Jaeschke A, Chatterjee TK, Weintraub NL, Hui DY.

J Biol Chem. 2012 Aug 10;287(33):27876-84. doi: 10.1074/jbc.M112.377549. Epub 2012 Jun 23.


The construction of ergonomic demands: application on artisan fishing using jangada fishing rafts in the beach of Ponta Negra.

Saldanha MC, Carvalho RJ, Oliveira LP, Celestino JE, Veloso IT, Jaeschke A.

Work. 2012;41 Suppl 1:628-35. doi: 10.3233/WOR-2012-0220-628.


Physical demands during the hauling of fishing nets for artisan fishing using rafts in beach of Ponta Negra, Natal--Brasil.

Jaeschke A, Saldanha MC.

Work. 2012;41 Suppl 1:414-21. doi: 10.3233/WOR-2012-0191-414.


Multiparity leads to obesity and inflammation in mothers and obesity in male offspring.

Rebholz SL, Jones T, Burke KT, Jaeschke A, Tso P, D'Alessio DA, Woollett LA.

Am J Physiol Endocrinol Metab. 2012 Feb 15;302(4):E449-57. doi: 10.1152/ajpendo.00487.2011. Epub 2011 Nov 29.


Cdc42 and Rac1 are major contributors to the saturated fatty acid-stimulated JNK pathway in hepatocytes.

Sharma M, Urano F, Jaeschke A.

J Hepatol. 2012 Jan;56(1):192-8. doi: 10.1016/j.jhep.2011.03.019. Epub 2011 May 18.


A multi-proxy study of anaerobic ammonium oxidation in marine sediments of the Gullmar Fjord, Sweden.

Brandsma J, van de Vossenberg J, Risgaard-Petersen N, Schmid MC, Engström P, Eurenius K, Hulth S, Jaeschke A, Abbas B, Hopmans EC, Strous M, Schouten S, Jetten MS, Damsté JS.

Environ Microbiol Rep. 2011 Jun;3(3):360-6. doi: 10.1111/j.1758-2229.2010.00233.x. Epub 2011 Jan 10.


Chronic dietary n-3 PUFA intervention improves dyslipidaemia and subsequent cardiovascular complications in the JCR:LA- cp rat model of the metabolic syndrome.

Lu J, Borthwick F, Hassanali Z, Wang Y, Mangat R, Ruth M, Shi D, Jaeschke A, Russell JC, Field CJ, Proctor SD, Vine DF.

Br J Nutr. 2011 Jun;105(11):1572-82. doi: 10.1017/S0007114510005453. Epub 2011 Jan 31.


Impact of temperature on ladderane lipid distribution in anammox bacteria.

Rattray JE, van de Vossenberg J, Jaeschke A, Hopmans EC, Wakeham SG, Lavik G, Kuypers MM, Strous M, Jetten MS, Schouten S, Sinninghe Damsté JS.

Appl Environ Microbiol. 2010 Mar;76(5):1596-603. doi: 10.1128/AEM.01796-09. Epub 2010 Jan 4.


16S rRNA gene and lipid biomarker evidence for anaerobic ammonium-oxidizing bacteria (anammox) in California and Nevada hot springs.

Jaeschke A, Op den Camp HJ, Harhangi H, Klimiuk A, Hopmans EC, Jetten MS, Schouten S, Sinninghe Damsté JS.

FEMS Microbiol Ecol. 2009 Mar;67(3):343-50. doi: 10.1111/j.1574-6941.2008.00640.x.


Presence and activity of anaerobic ammonium-oxidizing bacteria at deep-sea hydrothermal vents.

Byrne N, Strous M, Crépeau V, Kartal B, Birrien JL, Schmid M, Lesongeur F, Schouten S, Jaeschke A, Jetten M, Prieur D, Godfroy A.

ISME J. 2009 Jan;3(1):117-23. doi: 10.1038/ismej.2008.72. Epub 2008 Jul 31.


Metabolic stress signaling mediated by mixed-lineage kinases.

Jaeschke A, Davis RJ.

Mol Cell. 2007 Aug 3;27(3):498-508.


Oncogene addiction: role of signal attenuation.

Hübner A, Jaeschke A, Davis RJ.

Dev Cell. 2006 Dec;11(6):752-4.


JNK2 is a positive regulator of the cJun transcription factor.

Jaeschke A, Karasarides M, Ventura JJ, Ehrhardt A, Zhang C, Flavell RA, Shokat KM, Davis RJ.

Mol Cell. 2006 Sep 15;23(6):899-911.


Chemical genetic analysis of signal transduction pathways.

Jaeschke A, Davis RJ.

Expert Opin Ther Targets. 2006 Aug;10(4):485-8.


Improved analysis of ladderane lipids in biomass and sediments using high-performance liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry.

Hopmans EC, Kienhuis MV, Rattray JE, Jaeschke A, Schouten S, Damsté JS.

Rapid Commun Mass Spectrom. 2006;20(14):2099-103.


Disruption of the Jnk2 (Mapk9) gene reduces destructive insulitis and diabetes in a mouse model of type I diabetes.

Jaeschke A, Rincón M, Doran B, Reilly J, Neuberg D, Greiner DL, Shultz LD, Rossini AA, Flavell RA, Davis RJ.

Proc Natl Acad Sci U S A. 2005 May 10;102(19):6931-5. Epub 2005 May 2.


Role of MLK3 in the regulation of mitogen-activated protein kinase signaling cascades.

Brancho D, Ventura JJ, Jaeschke A, Doran B, Flavell RA, Davis RJ.

Mol Cell Biol. 2005 May;25(9):3670-81.


An essential role of the JIP1 scaffold protein for JNK activation in adipose tissue.

Jaeschke A, Czech MP, Davis RJ.

Genes Dev. 2004 Aug 15;18(16):1976-80.


mTOR: a mediator of intracellular homeostasis.

Jaeschke A, Dennis PB, Thomas G.

Curr Top Microbiol Immunol. 2004;279:283-98. Review.


Mechanism of p38 MAP kinase activation in vivo.

Brancho D, Tanaka N, Jaeschke A, Ventura JJ, Kelkar N, Tanaka Y, Kyuuma M, Takeshita T, Flavell RA, Davis RJ.

Genes Dev. 2003 Aug 15;17(16):1969-78. Epub 2003 Jul 31.


Tuberous sclerosis complex tumor suppressor-mediated S6 kinase inhibition by phosphatidylinositide-3-OH kinase is mTOR independent.

Jaeschke A, Hartkamp J, Saitoh M, Roworth W, Nobukuni T, Hodges A, Sampson J, Thomas G, Lamb R.

J Cell Biol. 2002 Oct 28;159(2):217-24. Epub 2002 Oct 28.


Mammalian TOR: a homeostatic ATP sensor.

Dennis PB, Jaeschke A, Saitoh M, Fowler B, Kozma SC, Thomas G.

Science. 2001 Nov 2;294(5544):1102-5.

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