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Items: 1 to 50 of 482

1.

Phototrophic purple bacteria as optoacoustic in vivo reporters of macrophage activity.

Peters L, Weidenfeld I, Klemm U, Loeschcke A, Weihmann R, Jaeger KE, Drepper T, Ntziachristos V, Stiel AC.

Nat Commun. 2019 Mar 13;10(1):1191. doi: 10.1038/s41467-019-09081-5.

2.

Tailoring the properties of (catalytically)-active inclusion bodies.

Jäger VD, Kloss R, Grünberger A, Seide S, Hahn D, Karmainski T, Piqueray M, Embruch J, Longerich S, Mackfeld U, Jaeger KE, Wiechert W, Pohl M, Krauss U.

Microb Cell Fact. 2019 Feb 7;18(1):33. doi: 10.1186/s12934-019-1081-5.

3.

How does the presence of neural probes affect extracellular potentials?

Buccino AP, Kuchta M, Jæger KH, Ness TV, Berthet P, Mardal KA, Cauwenberghs G, Tveito A.

J Neural Eng. 2019 Apr;16(2):026030. doi: 10.1088/1741-2552/ab03a1. Epub 2019 Jan 31.

PMID:
30703758
4.

Cornification of nail keratinocytes requires autophagy for bulk degradation of intracellular proteins while sparing components of the cytoskeleton.

Jaeger K, Sukseree S, Zhong S, Phinney BS, Mlitz V, Buchberger M, Narzt MS, Gruber F, Tschachler E, Rice RH, Eckhart L.

Apoptosis. 2019 Feb;24(1-2):62-73. doi: 10.1007/s10495-018-1505-4.

5.

Decoding the ocean's microbiological secrets for marine enzyme biodiscovery.

Ferrer M, Méndez-García C, Bargiela R, Chow J, Alonso S, García-Moyano A, Bjerga GEK, Steen IH, Schwabe T, Blom C, Vester J, Weckbecker A, Shahgaldian P, de Carvalho CCCR, Meskys R, Zanaroli G, Glöckner FO, Fernández-Guerra A, Thambisetty S, de la Calle F, Golyshina OV, Yakimov MM, Jaeger KE, Yakunin AF, Streit WR, McMeel O, Calewaert JB, Tonné N, Golyshin PN; INMARE Consortium.

FEMS Microbiol Lett. 2019 Jan 1;366(1). doi: 10.1093/femsle/fny285.

6.

Directed Evolution Empowered Redesign of Natural Proteins for the Sustainable Production of Chemicals and Pharmaceuticals.

Bornscheuer UT, Hauer B, Jaeger KE, Schwaneberg U.

Angew Chem Int Ed Engl. 2019 Jan 2;58(1):36-40. doi: 10.1002/anie.201812717. Epub 2018 Dec 6. Review.

PMID:
30520553
7.

Inversion and computational maturation of drug response using human stem cell derived cardiomyocytes in microphysiological systems.

Tveito A, Jæger KH, Huebsch N, Charrez B, Edwards AG, Wall S, Healy KE.

Sci Rep. 2018 Dec 4;8(1):17626. doi: 10.1038/s41598-018-35858-7.

8.

Bioprospecting Reveals Class III ω-Transaminases Converting Bulky Ketones and Environmentally Relevant Polyamines.

Coscolín C, Katzke N, García-Moyano A, Navarro-Fernández J, Almendral D, Martínez-Martínez M, Bollinger A, Bargiela R, Gertler C, Chernikova TN, Rojo D, Barbas C, Tran H, Golyshina OV, Koch R, Yakimov MM, Bjerga GEK, Golyshin PN, Jaeger KE, Ferrer M.

Appl Environ Microbiol. 2019 Jan 9;85(2). pii: e02404-18. doi: 10.1128/AEM.02404-18. Print 2019 Jan 15.

9.

An optogenetic toolbox of LOV-based photosensitizers for light-driven killing of bacteria.

Endres S, Wingen M, Torra J, Ruiz-González R, Polen T, Bosio G, Bitzenhofer NL, Hilgers F, Gensch T, Nonell S, Jaeger KE, Drepper T.

Sci Rep. 2018 Oct 9;8(1):15021. doi: 10.1038/s41598-018-33291-4.

10.

A Synthetic Reaction Cascade Implemented by Colocalization of Two Proteins within Catalytically Active Inclusion Bodies.

Jäger VD, Lamm R, Kloß R, Kaganovitch E, Grünberger A, Pohl M, Büchs J, Jaeger KE, Krauss U.

ACS Synth Biol. 2018 Sep 21;7(9):2282-2295. doi: 10.1021/acssynbio.8b00274. Epub 2018 Aug 20.

PMID:
30053372
11.

Natural biocide cocktails: Combinatorial antibiotic effects of prodigiosin and biosurfactants.

Hage-Hülsmann J, Grünberger A, Thies S, Santiago-Schübel B, Klein AS, Pietruszka J, Binder D, Hilgers F, Domröse A, Drepper T, Kohlheyer D, Jaeger KE, Loeschcke A.

PLoS One. 2018 Jul 19;13(7):e0200940. doi: 10.1371/journal.pone.0200940. eCollection 2018.

12.

Mechanistic Basis of the Fast Dark Recovery of the Short LOV Protein DsLOV from Dinoroseobacter shibae.

Fettweiss T, Röllen K, Granzin J, Reiners O, Endres S, Drepper T, Willbold D, Jaeger KE, Batra-Safferling R, Krauss U.

Biochemistry. 2018 Aug 14;57(32):4833-4847. doi: 10.1021/acs.biochem.8b00645. Epub 2018 Jul 24.

PMID:
29989797
13.

Disruption of microbial community composition and identification of plant growth promoting microorganisms after exposure of soil to rapeseed-derived glucosinolates.

Siebers M, Rohr T, Ventura M, Schütz V, Thies S, Kovacic F, Jaeger KE, Berg M, Dörmann P, Schulz M.

PLoS One. 2018 Jul 3;13(7):e0200160. doi: 10.1371/journal.pone.0200160. eCollection 2018.

14.

The biotechnological potential of marine bacteria in the novel lineage of Pseudomonas pertucinogena.

Bollinger A, Thies S, Katzke N, Jaeger KE.

Microb Biotechnol. 2018 Jun 25. doi: 10.1111/1751-7915.13288. [Epub ahead of print] Review.

15.

Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser.

Nogly P, Weinert T, James D, Carbajo S, Ozerov D, Furrer A, Gashi D, Borin V, Skopintsev P, Jaeger K, Nass K, Båth P, Bosman R, Koglin J, Seaberg M, Lane T, Kekilli D, Brünle S, Tanaka T, Wu W, Milne C, White T, Barty A, Weierstall U, Panneels V, Nango E, Iwata S, Hunter M, Schapiro I, Schertler G, Neutze R, Standfuss J.

Science. 2018 Jul 13;361(6398). pii: eaat0094. doi: 10.1126/science.aat0094. Epub 2018 Jun 14.

PMID:
29903883
16.

Inter-observer variation of hippocampus delineation in hippocampal avoidance prophylactic cranial irradiation.

Bartel F, van Herk M, Vrenken H, Vandaele F, Sunaert S, de Jaeger K, Dollekamp NJ, Carbaat C, Lamers E, Dieleman EMT, Lievens Y, de Ruysscher D, Schagen SB, de Ruiter MB, de Munck JC, Belderbos J.

Clin Transl Oncol. 2019 Feb;21(2):178-186. doi: 10.1007/s12094-018-1903-7. Epub 2018 Jun 6.

PMID:
29876759
17.

Preparation of Cyclic Prodiginines by Mutasynthesis in Pseudomonas putida KT2440.

Klein AS, Brass HUC, Klebl DP, Classen T, Loeschcke A, Drepper T, Sievers S, Jaeger KE, Pietruszka J.

Chembiochem. 2018 May 2. doi: 10.1002/cbic.201800154. [Epub ahead of print]

PMID:
29719131
18.

Impact of brachytherapy technique (2D versus 3D) on outcome following radiotherapy of cervical cancer.

Derks K, Steenhuijsen JLG, van den Berg HA, Houterman S, Cnossen J, van Haaren P, De Jaeger K.

J Contemp Brachytherapy. 2018 Feb;10(1):17-25. doi: 10.5114/jcb.2018.73955. Epub 2018 Feb 22.

19.

Unraveling the effects of amino acid substitutions enhancing lipase resistance to an ionic liquid: a molecular dynamics study.

Zhao J, Frauenkron-Machedjou VJ, Fulton A, Zhu L, Davari MD, Jaeger KE, Schwaneberg U, Bocola M.

Phys Chem Chem Phys. 2018 Apr 4;20(14):9600-9609. doi: 10.1039/c7cp08470f.

PMID:
29578220
20.

Rapid generation of recombinant Pseudomonas putida secondary metabolite producers using yTREX.

Domröse A, Weihmann R, Thies S, Jaeger KE, Drepper T, Loeschcke A.

Synth Syst Biotechnol. 2017 Nov 15;2(4):310-319. doi: 10.1016/j.synbio.2017.11.001. eCollection 2017 Dec.

21.

Chloroplast Signaling Gates Thermotolerance in Arabidopsis.

Dickinson PJ, Kumar M, Martinho C, Yoo SJ, Lan H, Artavanis G, Charoensawan V, Schöttler MA, Bock R, Jaeger KE, Wigge PA.

Cell Rep. 2018 Feb 13;22(7):1657-1665. doi: 10.1016/j.celrep.2018.01.054.

22.

Online measurement of the respiratory activity in shake flasks enables the identification of cultivation phases and patterns indicating recombinant protein production in various Escherichia coli host strains.

Ihling N, Bittner N, Diederichs S, Schelden M, Korona A, Höfler GT, Fulton A, Jaeger KE, Honda K, Ohtake H, Büchs J.

Biotechnol Prog. 2018 Mar;34(2):315-327. doi: 10.1002/btpr.2600. Epub 2018 Jan 17.

PMID:
29314728
23.

Corrigendum: Directionality of substrate translocation of the hemolysin A Type I secretion system.

Lenders MHH, Weidtkamp-Peters S, Kleinschrodt D, Jaeger KE, Smits SHJ, Schmitt L.

Sci Rep. 2018 Jan 8;8:46926. doi: 10.1038/srep46926.

24.

The photosynthetic bacteria Rhodobacter capsulatus and Synechocystis sp. PCC 6803 as new hosts for cyclic plant triterpene biosynthesis.

Loeschcke A, Dienst D, Wewer V, Hage-Hülsmann J, Dietsch M, Kranz-Finger S, Hüren V, Metzger S, Urlacher VB, Gigolashvili T, Kopriva S, Axmann IM, Drepper T, Jaeger KE.

PLoS One. 2017 Dec 27;12(12):e0189816. doi: 10.1371/journal.pone.0189816. eCollection 2017.

25.

Heterologous production of long-chain rhamnolipids from Burkholderia glumae in Pseudomonas putida-a step forward to tailor-made rhamnolipids.

Wittgens A, Santiago-Schuebel B, Henkel M, Tiso T, Blank LM, Hausmann R, Hofmann D, Wilhelm S, Jaeger KE, Rosenau F.

Appl Microbiol Biotechnol. 2018 Feb;102(3):1229-1239. doi: 10.1007/s00253-017-8702-x. Epub 2017 Dec 20.

PMID:
29264775
26.

Interobserver variability in the delineation of the primary lung cancer and lymph nodes on different four-dimensional computed tomography reconstructions.

Mercieca S, Belderbos JSA, De Jaeger K, Schinagl DAX, van der Voort Van Zijp N, Pomp J, Theuws J, Khalifa J, van de Vaart P, van Herk M.

Radiother Oncol. 2018 Feb;126(2):325-332. doi: 10.1016/j.radonc.2017.11.020. Epub 2017 Dec 5.

PMID:
29208512
27.

Fast automated online xylanase activity assay using HPAEC-PAD.

Cürten C, Anders N, Juchem N, Ihling N, Volkenborn K, Knapp A, Jaeger KE, Büchs J, Spiess AC.

Anal Bioanal Chem. 2018 Jan;410(1):57-69. doi: 10.1007/s00216-017-0712-0. Epub 2017 Nov 28.

PMID:
29184998
28.

Determinants and Prediction of Esterase Substrate Promiscuity Patterns.

Martínez-Martínez M, Coscolín C, Santiago G, Chow J, Stogios PJ, Bargiela R, Gertler C, Navarro-Fernández J, Bollinger A, Thies S, Méndez-García C, Popovic A, Brown G, Chernikova TN, García-Moyano A, Bjerga GEK, Pérez-García P, Hai T, Del Pozo MV, Stokke R, Steen IH, Cui H, Xu X, Nocek BP, Alcaide M, Distaso M, Mesa V, Peláez AI, Sánchez J, Buchholz PCF, Pleiss J, Fernández-Guerra A, Glöckner FO, Golyshina OV, Yakimov MM, Savchenko A, Jaeger KE, Yakunin AF, Streit WR, Golyshin PN, Guallar V, Ferrer M, The Inmare Consortium.

ACS Chem Biol. 2018 Jan 19;13(1):225-234. doi: 10.1021/acschembio.7b00996. Epub 2017 Dec 20.

PMID:
29182315
29.

High-Throughput Screening Assays for Lipolytic Enzymes.

Fulton A, Hayes MR, Schwaneberg U, Pietruszka J, Jaeger KE.

Methods Mol Biol. 2018;1685:209-231. doi: 10.1007/978-1-4939-7366-8_12.

PMID:
29086311
30.

Electron transfer pathways in a light, oxygen, voltage (LOV) protein devoid of the photoactive cysteine.

Kopka B, Magerl K, Savitsky A, Davari MD, Röllen K, Bocola M, Dick B, Schwaneberg U, Jaeger KE, Krauss U.

Sci Rep. 2017 Oct 17;7(1):13346. doi: 10.1038/s41598-017-13420-1.

31.

An A/U-Rich Enhancer Region Is Required for High-Level Protein Secretion through the HlyA Type I Secretion System.

Khosa S, Scholz R, Schwarz C, Trilling M, Hengel H, Jaeger KE, Smits SHJ, Schmitt L.

Appl Environ Microbiol. 2017 Dec 15;84(1). pii: e01163-17. doi: 10.1128/AEM.01163-17. Print 2018 Jan 1.

32.

Contribution of single amino acid and codon substitutions to the production and secretion of a lipase by Bacillus subtilis.

Skoczinski P, Volkenborn K, Fulton A, Bhadauriya A, Nutschel C, Gohlke H, Knapp A, Jaeger KE.

Microb Cell Fact. 2017 Sep 25;16(1):160. doi: 10.1186/s12934-017-0772-z.

33.

Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons.

Weinert T, Olieric N, Cheng R, Brünle S, James D, Ozerov D, Gashi D, Vera L, Marsh M, Jaeger K, Dworkowski F, Panepucci E, Basu S, Skopintsev P, Doré AS, Geng T, Cooke RM, Liang M, Prota AE, Panneels V, Nogly P, Ermler U, Schertler G, Hennig M, Steinmetz MO, Wang M, Standfuss J.

Nat Commun. 2017 Sep 14;8(1):542. doi: 10.1038/s41467-017-00630-4.

34.

Transcriptional Regulation of the Ambient Temperature Response by H2A.Z Nucleosomes and HSF1 Transcription Factors in Arabidopsis.

Cortijo S, Charoensawan V, Brestovitsky A, Buning R, Ravarani C, Rhodes D, van Noort J, Jaeger KE, Wigge PA.

Mol Plant. 2017 Oct 9;10(10):1258-1273. doi: 10.1016/j.molp.2017.08.014. Epub 2017 Sep 8.

35.

40 Years of Biotechnology Research at Forschungszentrum Jülich.

Bott M, Jaeger KE, Pietruszka J, Wiechert W.

J Biotechnol. 2017 Sep 20;258:1. doi: 10.1016/j.jbiotec.2017.08.014. No abstract available.

PMID:
28890231
36.

The G-Box Transcriptional Regulatory Code in Arabidopsis.

Ezer D, Shepherd SJK, Brestovitsky A, Dickinson P, Cortijo S, Charoensawan V, Box MS, Biswas S, Jaeger KE, Wigge PA.

Plant Physiol. 2017 Oct;175(2):628-640. doi: 10.1104/pp.17.01086. Epub 2017 Sep 1.

37.

First Insights into the Genome Sequence of Pseudomonas oleovorans DSM 1045.

Poehlein A, Daniel R, Thürmer A, Bollinger A, Thies S, Katzke N, Jaeger KE.

Genome Announc. 2017 Aug 10;5(32). pii: e00774-17. doi: 10.1128/genomeA.00774-17.

38.

The evening complex coordinates environmental and endogenous signals in Arabidopsis.

Ezer D, Jung JH, Lan H, Biswas S, Gregoire L, Box MS, Charoensawan V, Cortijo S, Lai X, Stöckle D, Zubieta C, Jaeger KE, Wigge PA.

Nat Plants. 2017 Jun 26;3:17087. doi: 10.1038/nplants.2017.87.

39.

Homogenizing bacterial cell factories: Analysis and engineering of phenotypic heterogeneity.

Binder D, Drepper T, Jaeger KE, Delvigne F, Wiechert W, Kohlheyer D, Grünberger A.

Metab Eng. 2017 Jul;42:145-156. doi: 10.1016/j.ymben.2017.06.009. Epub 2017 Jun 20. Review.

PMID:
28645641
40.

Activity-independent screening of secreted proteins using split GFP.

Knapp A, Ripphahn M, Volkenborn K, Skoczinski P, Jaeger KE.

J Biotechnol. 2017 Sep 20;258:110-116. doi: 10.1016/j.jbiotec.2017.05.024. Epub 2017 Jun 12.

41.

New Prodigiosin Derivatives Obtained by Mutasynthesis in Pseudomonas putida.

Klein AS, Domröse A, Bongen P, Brass HUC, Classen T, Loeschcke A, Drepper T, Laraia L, Sievers S, Jaeger KE, Pietruszka J.

ACS Synth Biol. 2017 Sep 15;6(9):1757-1765. doi: 10.1021/acssynbio.7b00099. Epub 2017 May 26.

PMID:
28505410
42.

A novel FbFP-based biosensor toolbox for sensitive in vivo determination of intracellular pH.

Rupprecht C, Wingen M, Potzkei J, Gensch T, Jaeger KE, Drepper T.

J Biotechnol. 2017 Sep 20;258:25-32. doi: 10.1016/j.jbiotec.2017.05.006. Epub 2017 May 10.

PMID:
28501596
43.

Novel Thermostable Flavin-binding Fluorescent Proteins from Thermophilic Organisms.

Wingen M, Jaeger KE, Gensch T, Drepper T.

Photochem Photobiol. 2017 May;93(3):849-856. doi: 10.1111/php.12740.

PMID:
28500719
44.

An Evaluation of the Accuracy of Classical Models for Computing the Membrane Potential and Extracellular Potential for Neurons.

Tveito A, Jæger KH, Lines GT, Paszkowski Ł, Sundnes J, Edwards AG, Māki-Marttunen T, Halnes G, Einevoll GT.

Front Comput Neurosci. 2017 Apr 24;11:27. doi: 10.3389/fncom.2017.00027. eCollection 2017.

45.

Catalytically-active inclusion bodies-Carrier-free protein immobilizates for application in biotechnology and biomedicine.

Krauss U, Jäger VD, Diener M, Pohl M, Jaeger KE.

J Biotechnol. 2017 Sep 20;258:136-147. doi: 10.1016/j.jbiotec.2017.04.033. Epub 2017 Apr 30.

PMID:
28465211
46.

Diagnoseleistung des MelaFind-Geräts im klinischen Alltag.

Fink C, Jaeger C, Jaeger K, Haenssle HA.

J Dtsch Dermatol Ges. 2017 Apr;15(4):414-420. doi: 10.1111/ddg.13220_g. No abstract available.

PMID:
28378486
47.

Diagnostic performance of the MelaFind device in a real-life clinical setting.

Fink C, Jaeger C, Jaeger K, Haenssle HA.

J Dtsch Dermatol Ges. 2017 Apr;15(4):414-419. doi: 10.1111/ddg.13220. Epub 2017 Mar 23.

PMID:
28332777
48.

A combination of mutational and computational scanning guides the design of an artificial ligand-binding controlled lipase.

Kaschner M, Schillinger O, Fettweiss T, Nutschel C, Krause F, Fulton A, Strodel B, Stadler A, Jaeger KE, Krauss U.

Sci Rep. 2017 Feb 20;7:42592. doi: 10.1038/srep42592.

49.

Structure of a LOV protein in apo-state and implications for construction of LOV-based optical tools.

Arinkin V, Granzin J, Röllen K, Krauss U, Jaeger KE, Willbold D, Batra-Safferling R.

Sci Rep. 2017 Feb 17;7:42971. doi: 10.1038/srep42971.

50.

Transmission of Metabolic Dysfunction Across Generations.

Jaeger K, Saben JL, Moley KH.

Physiology (Bethesda). 2017 Jan;32(1):51-59. Review.

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