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The role of FAPI-PET/CT for patients with malignancies of the lower gastrointestinal tract - first clinical experience.

Koerber SA, Staudinger F, Kratochwil C, Adeberg S, Haefner MF, Ungerechts G, Rathke H, Winter E, Lindner T, Syed M, Bhatti IA, Herfarth K, Choyke PL, Jaeger D, Haberkorn U, Debus J, Giesel FL.

J Nucl Med. 2020 Feb 14. pii: jnumed.119.237016. doi: 10.2967/jnumed.119.237016. [Epub ahead of print]


A general method to generate artificial spike train populations matching recorded neurons.

Abbasi S, Maran S, Jaeger D.

J Comput Neurosci. 2020 Feb;48(1):47-63. doi: 10.1007/s10827-020-00741-w. Epub 2020 Jan 23.


Unilateral Optogenetic Inhibition and Excitation of Basal Ganglia Output Affect Directional Lick Choices and Movement Initiation in Mice.

Morrissette AE, Chen PH, Bhamani C, Borden PY, Waiblinger C, Stanley GB, Jaeger D.

Neuroscience. 2019 Dec 15;423:55-65. doi: 10.1016/j.neuroscience.2019.10.031. Epub 2019 Nov 6.


Effect of bystander CPR initiated by a dispatch centre following out-of-hospital cardiac arrest on 30-day survival: Adjusted results from the French National Cardiac Arrest Registry.

Noel L, Jaeger D, Baert V, Debaty G, Genin M, Sadoune S, Bassand A, Tazarourte K, Gueugniaud PY, El Khoury C, Hubert H, Chouihed T; GR-RéAC.

Resuscitation. 2019 Nov;144:91-98. doi: 10.1016/j.resuscitation.2019.08.032. Epub 2019 Sep 6.


Accuracy of Several Lung Ultrasound Methods for the Diagnosis of Acute Heart Failure in the ED: A Multicenter Prospective Study.

Buessler A, Chouihed T, Duarte K, Bassand A, Huot-Marchand M, Gottwalles Y, Pénine A, André E, Nace L, Jaeger D, Kobayashi M, Coiro S, Rossignol P, Girerd N.

Chest. 2020 Jan;157(1):99-110. doi: 10.1016/j.chest.2019.07.017. Epub 2019 Aug 2.


Recent Advances Targeting CCR5 for Cancer and Its Role in Immuno-Oncology.

Jiao X, Nawab O, Patel T, Kossenkov AV, Halama N, Jaeger D, Pestell RG.

Cancer Res. 2019 Oct 1;79(19):4801-4807. doi: 10.1158/0008-5472.CAN-19-1167. Epub 2019 Jul 10. Review.


Reduction of the event-related potential P3 in preterm born 5-year-old healthy children.

Jaeger DA, Gawehn N, Schölmerich A, Schneider DT, Suchan B.

Clin Neurophysiol. 2019 May;130(5):675-682. doi: 10.1016/j.clinph.2019.02.003. Epub 2019 Feb 19.


Diagnostic and prognostic value of plasma volume status at emergency department admission in dyspneic patients: results from the PARADISE cohort.

Chouihed T, Rossignol P, Bassand A, Duarte K, Kobayashi M, Jaeger D, Sadoune S, Buessler A, Nace L, Giacomin G, Hutter T, Barbé F, Salignac S, Jay N, Zannad F, Girerd N.

Clin Res Cardiol. 2019 May;108(5):563-573. doi: 10.1007/s00392-018-1388-y. Epub 2018 Oct 28.


Targeted and immuno-biology driven treatment strategies for triple-negative breast cancer: current knowledge and future perspectives.

Fremd C, Jaeger D, Schneeweiss A.

Expert Rev Anticancer Ther. 2019 Jan;19(1):29-42. doi: 10.1080/14737140.2019.1537785. Epub 2018 Oct 29.


COOLHAIR: a prospective randomized trial to investigate the efficacy and tolerability of scalp cooling in patients undergoing (neo)adjuvant chemotherapy for early breast cancer.

Smetanay K, Junio P, Feißt M, Seitz J, Hassel JC, Mayer L, Matthies LM, Schumann A, Hennigs A, Heil J, Sohn C, Jaeger D, Schneeweiss A, Marmé F.

Breast Cancer Res Treat. 2019 Jan;173(1):135-143. doi: 10.1007/s10549-018-4983-8. Epub 2018 Sep 25.


CheckMate-032 Study: Efficacy and Safety of Nivolumab and Nivolumab Plus Ipilimumab in Patients With Metastatic Esophagogastric Cancer.

Janjigian YY, Bendell J, Calvo E, Kim JW, Ascierto PA, Sharma P, Ott PA, Peltola K, Jaeger D, Evans J, de Braud F, Chau I, Harbison CT, Dorange C, Tschaika M, Le DT.

J Clin Oncol. 2018 Oct 1;36(28):2836-2844. doi: 10.1200/JCO.2017.76.6212. Epub 2018 Aug 15. Erratum in: J Clin Oncol. 2019 Feb 10;37(5):443.


High-Throughput Screening of Combinatorial Immunotherapies with Patient-Specific In Silico Models of Metastatic Colorectal Cancer.

Kather JN, Charoentong P, Suarez-Carmona M, Herpel E, Klupp F, Ulrich A, Schneider M, Zoernig I, Luedde T, Jaeger D, Poleszczuk J, Halama N.

Cancer Res. 2018 Sep 1;78(17):5155-5163. doi: 10.1158/0008-5472.CAN-18-1126. Epub 2018 Jul 2.


A precision oncology approach to the pharmacological targeting of mechanistic dependencies in neuroendocrine tumors.

Alvarez MJ, Subramaniam PS, Tang LH, Grunn A, Aburi M, Rieckhof G, Komissarova EV, Hagan EA, Bodei L, Clemons PA, Dela Cruz FS, Dhall D, Diolaiti D, Fraker DA, Ghavami A, Kaemmerer D, Karan C, Kidd M, Kim KM, Kim HC, Kunju LP, Langel Ü, Li Z, Lee J, Li H, LiVolsi V, Pfragner R, Rainey AR, Realubit RB, Remotti H, Regberg J, Roses R, Rustgi A, Sepulveda AR, Serra S, Shi C, Yuan X, Barberis M, Bergamaschi R, Chinnaiyan AM, Detre T, Ezzat S, Frilling A, Hommann M, Jaeger D, Kim MK, Knudsen BS, Kung AL, Leahy E, Metz DC, Milsom JW, Park YS, Reidy-Lagunes D, Schreiber S, Washington K, Wiedenmann B, Modlin I, Califano A.

Nat Genet. 2018 Jul;50(7):979-989. doi: 10.1038/s41588-018-0138-4. Epub 2018 Jun 18.


Hyponatraemia, hyperglycaemia and worsening renal function at first blood sample on emergency department admission as predictors of in-hospital death in patients with dyspnoea with suspected acute heart failure: retrospective observational analysis of the PARADISE cohort.

Chouihed T, Buessler A, Bassand A, Jaeger D, Virion JM, Nace L, Barbé F, Salignac S, Rossignol P, Zannad F, Girerd N.

BMJ Open. 2018 Mar 30;8(3):e019557. doi: 10.1136/bmjopen-2017-019557.


Benefit of immediate coronary angiography after out-of-hospital cardiac arrest in France: A nationwide propensity score analysis from the RéAC Registry.

Jaeger D, Dumas F, Escutnaire J, Sadoune S, Lauvray A, Elkhoury C, Bassand A, Girerd N, Gueugniaud PY, Tazarourte K, Hubert H, Cariou A, Chouihed T; Reac Group.

Resuscitation. 2018 May;126:90-97. doi: 10.1016/j.resuscitation.2018.03.003. Epub 2018 Mar 5.


Genomics and emerging biomarkers for immunotherapy of colorectal cancer.

Kather JN, Halama N, Jaeger D.

Semin Cancer Biol. 2018 Oct;52(Pt 2):189-197. doi: 10.1016/j.semcancer.2018.02.010. Epub 2018 Mar 1. Review.


Targeted BiTE Expression by an Oncolytic Vector Augments Therapeutic Efficacy Against Solid Tumors.

Speck T, Heidbuechel JPW, Veinalde R, Jaeger D, von Kalle C, Ball CR, Ungerechts G, Engeland CE.

Clin Cancer Res. 2018 May 1;24(9):2128-2137. doi: 10.1158/1078-0432.CCR-17-2651. Epub 2018 Feb 6.


Phase II trial of ipilimumab in melanoma patients with preexisting humoural immune response to NY-ESO-1.

Haag GM, Zoernig I, Hassel JC, Halama N, Dick J, Lang N, Podola L, Funk J, Ziegelmeier C, Juenger S, Bucur M, Umansky L, Falk CS, Freitag A, Karapanagiotou-Schenkel I, Beckhove P, Enk A, Jaeger D.

Eur J Cancer. 2018 Feb;90:122-129. doi: 10.1016/j.ejca.2017.12.001. Epub 2018 Jan 5.


Exceptional increase in the creep life of magnesium rare-earth alloys due to localized bond stiffening.

Choudhuri D, Srinivasan SG, Gibson MA, Zheng Y, Jaeger DL, Fraser HL, Banerjee R.

Nat Commun. 2017 Dec 8;8(1):2000. doi: 10.1038/s41467-017-02112-z.


Cerebellar Purkinje Cells Generate Highly Correlated Spontaneous Slow-Rate Fluctuations.

Cao Y, Liu Y, Jaeger D, Heck DH.

Front Neural Circuits. 2017 Sep 20;11:67. doi: 10.3389/fncir.2017.00067. eCollection 2017.


Isolation and Structural Characterization of Echinocystic Acid Triterpenoid Saponins from the Australian Medicinal and Food Plant Acacia ligulata.

Jæger D, Ndi CP, Crocoll C, Simpson BS, Khakimov B, Guzman-Genuino RM, Hayball JD, Xing X, Bulone V, Weinstein P, Møller BL, Semple SJ.

J Nat Prod. 2017 Oct 27;80(10):2692-2698. doi: 10.1021/acs.jnatprod.7b00437. Epub 2017 Oct 4.


Time-resolved transcriptome analysis and lipid pathway reconstruction of the oleaginous green microalga Monoraphidium neglectum reveal a model for triacylglycerol and lipid hyperaccumulation.

Jaeger D, Winkler A, Mussgnug JH, Kalinowski J, Goesmann A, Kruse O.

Biotechnol Biofuels. 2017 Aug 14;10:197. doi: 10.1186/s13068-017-0882-1. eCollection 2017.


Randomized controlled trial of S-1 maintenance therapy in metastatic esophagogastric cancer - the multinational MATEO study.

Haag GM, Stocker G, Quidde J, Jaeger D, Lordick F.

BMC Cancer. 2017 Jul 31;17(1):509. doi: 10.1186/s12885-017-3497-9.


Erratum: Genetically expressed voltage sensor ArcLight for imaging large scale cortical activity in the anesthetized and awake mouse (erratum).

Borden PY, Ortiz AD, Waiblinger C, Sederberg AJ, Morrissette AE, Forest CR, Jaeger D, Stanley GB.

Neurophotonics. 2017 Jul;4(3):039801. doi: 10.1117/1.NPh.4.3.039801. Epub 2017 Jul 20.


Improving Patient Selection for Refractory Out of Hospital Cardiac Arrest Treated with Extracorporeal Life Support.

Chouihed T, Kimmoun A, Lauvray A, Laithier FX, Jaeger D, Lemoine S, Maureira JP, Nace L, Duarte K, Albizzati S, Girerd N, Levy B.

Shock. 2018 Jan;49(1):24-28. doi: 10.1097/SHK.0000000000000941.


Robust transmission of rate coding in the inhibitory Purkinje cell to cerebellar nuclei pathway in awake mice.

Abbasi S, Hudson AE, Maran SK, Cao Y, Abbasi A, Heck DH, Jaeger D.

PLoS Comput Biol. 2017 Jun 15;13(6):e1005578. doi: 10.1371/journal.pcbi.1005578. eCollection 2017 Jun.


Genetically expressed voltage sensor ArcLight for imaging large scale cortical activity in the anesthetized and awake mouse.

Borden PY, Ortiz AD, Waiblinger C, Sederberg AJ, Morrissette AE, Forest CR, Jaeger D, Stanley GB.

Neurophotonics. 2017 Jul;4(3):031212. doi: 10.1117/1.NPh.4.3.031212. Epub 2017 May 4. Erratum in: Neurophotonics. 2017 Jul;4(3):039801.


Biological activity and LC-MS/MS profiling of extracts from the Australian medicinal plant Acacia ligulata (Fabaceae).

Jæger D, Simpson BS, Ndi CP, Jäger AK, Crocoll C, Møller BL, Weinstein P, Semple SJ.

Nat Prod Res. 2018 Mar;32(5):576-581. doi: 10.1080/14786419.2017.1318383. Epub 2017 Apr 21.


Detailed resolution analysis reveals spatial T cell heterogeneity in the invasive margin of colorectal cancer liver metastases associated with improved survival.

Berthel A, Zoernig I, Valous NA, Kahlert C, Klupp F, Ulrich A, Weitz J, Jaeger D, Halama N.

Oncoimmunology. 2017 Feb 23;6(3):e1286436. doi: 10.1080/2162402X.2017.1286436. eCollection 2017.


Nuclear transformation and functional gene expression in the oleaginous microalga Monoraphidium neglectum.

Jaeger D, Hübner W, Huser T, Mussgnug JH, Kruse O.

J Biotechnol. 2017 May 10;249:10-15. doi: 10.1016/j.jbiotec.2017.03.011. Epub 2017 Mar 14.


Randomized, Double-Blind, Phase III Trial of Ipilimumab Versus Placebo in Asymptomatic or Minimally Symptomatic Patients With Metastatic Chemotherapy-Naive Castration-Resistant Prostate Cancer.

Beer TM, Kwon ED, Drake CG, Fizazi K, Logothetis C, Gravis G, Ganju V, Polikoff J, Saad F, Humanski P, Piulats JM, Gonzalez Mella P, Ng SS, Jaeger D, Parnis FX, Franke FA, Puente J, Carvajal R, Sengeløv L, McHenry MB, Varma A, van den Eertwegh AJ, Gerritsen W.

J Clin Oncol. 2017 Jan;35(1):40-47. Epub 2016 Oct 31.


Parallel pathways from whisker and visual sensory cortices to distinct frontal regions of mouse neocortex.

Sreenivasan V, Kyriakatos A, Mateo C, Jaeger D, Petersen CC.

Neurophotonics. 2017 Jul;4(3):031203. Epub 2016 Nov 23.


The AP-1 transcription factor JunB is essential for multiple myeloma cell proliferation and drug resistance in the bone marrow microenvironment.

Fan F, Bashari MH, Morelli E, Tonon G, Malvestiti S, Vallet S, Jarahian M, Seckinger A, Hose D, Bakiri L, Sun C, Hu Y, Ball CR, Glimm H, Sattler M, Goldschmidt H, Wagner EF, Tassone P, Jaeger D, Podar K.

Leukemia. 2017 Jul;31(7):1570-1581. doi: 10.1038/leu.2016.358. Epub 2016 Nov 28.


Label-free in vivo analysis of intracellular lipid droplets in the oleaginous microalga Monoraphidium neglectum by coherent Raman scattering microscopy.

Jaeger D, Pilger C, Hachmeister H, Oberländer E, Wördenweber R, Wichmann J, Mussgnug JH, Huser T, Kruse O.

Sci Rep. 2016 Oct 21;6:35340. doi: 10.1038/srep35340.


Nivolumab monotherapy in recurrent metastatic urothelial carcinoma (CheckMate 032): a multicentre, open-label, two-stage, multi-arm, phase 1/2 trial.

Sharma P, Callahan MK, Bono P, Kim J, Spiliopoulou P, Calvo E, Pillai RN, Ott PA, de Braud F, Morse M, Le DT, Jaeger D, Chan E, Harbison C, Lin CS, Tschaika M, Azrilevich A, Rosenberg JE.

Lancet Oncol. 2016 Nov;17(11):1590-1598. doi: 10.1016/S1470-2045(16)30496-X. Epub 2016 Oct 9. Erratum in: Lancet Oncol. 2019 Feb;20(2):e71.


Bcl-xL is an oncogenic driver in colorectal cancer.

Scherr AL, Gdynia G, Salou M, Radhakrishnan P, Duglova K, Heller A, Keim S, Kautz N, Jassowicz A, Elssner C, He YW, Jaeger D, Heikenwalder M, Schneider M, Weber A, Roth W, Schulze-Bergkamen H, Koehler BC.

Cell Death Dis. 2016 Aug 18;7(8):e2342. doi: 10.1038/cddis.2016.233.


Optogenetic stimulation of cortico-subthalamic projections is sufficient to ameliorate bradykinesia in 6-ohda lesioned mice.

Sanders TH, Jaeger D.

Neurobiol Dis. 2016 Nov;95:225-37. doi: 10.1016/j.nbd.2016.07.021. Epub 2016 Jul 21.


Exercise and cancer: return to work as a firefighter with ostomy after rectal carcinoma - a case report.

Wiskemann J, Schommer K, Jaeger D, Scharhag-Rosenberger F.

Medicine (Baltimore). 2016 Jul;95(29):e4309. doi: 10.1097/MD.0000000000004309.


The Roles of the Olivocerebellar Pathway in Motor Learning and Motor Control. A Consensus Paper.

Lang EJ, Apps R, Bengtsson F, Cerminara NL, De Zeeuw CI, Ebner TJ, Heck DH, Jaeger D, Jörntell H, Kawato M, Otis TS, Ozyildirim O, Popa LS, Reeves AM, Schweighofer N, Sugihara I, Xiao J.

Cerebellum. 2017 Feb;16(1):230-252. doi: 10.1007/s12311-016-0787-8.


Signals of speciation: volatile organic compounds resolve closely related sagebrush taxa, suggesting their importance in evolution.

Jaeger DM, Runyon JB, Richardson BA.

New Phytol. 2016 Sep;211(4):1393-401. doi: 10.1111/nph.13982. Epub 2016 Apr 26.


Tumoral Immune Cell Exploitation in Colorectal Cancer Metastases Can Be Targeted Effectively by Anti-CCR5 Therapy in Cancer Patients.

Halama N, Zoernig I, Berthel A, Kahlert C, Klupp F, Suarez-Carmona M, Suetterlin T, Brand K, Krauss J, Lasitschka F, Lerchl T, Luckner-Minden C, Ulrich A, Koch M, Weitz J, Schneider M, Buechler MW, Zitvogel L, Herrmann T, Benner A, Kunz C, Luecke S, Springfeld C, Grabe N, Falk CS, Jaeger D.

Cancer Cell. 2016 Apr 11;29(4):587-601. doi: 10.1016/j.ccell.2016.03.005.


Cerebellar Nuclei Neurons Show Only Small Excitatory Responses to Optogenetic Olivary Stimulation in Transgenic Mice: In Vivo and In Vitro Studies.

Lu H, Yang B, Jaeger D.

Front Neural Circuits. 2016 Mar 24;10:21. doi: 10.3389/fncir.2016.00021. eCollection 2016.


Outcomes and risk factors for cancer patients undergoing endoscopic intervention of malignant biliary obstruction.

Haag GM, Herrmann T, Jaeger D, Stremmel W, Schemmer P, Sauer P, Gotthardt DN.

BMC Gastroenterol. 2015 Dec 4;15:171. doi: 10.1186/s12876-015-0399-7.


Pan-Bcl-2 inhibitor Obatoclax is a potent late stage autophagy inhibitor in colorectal cancer cells independent of canonical autophagy signaling.

Koehler BC, Jassowicz A, Scherr AL, Lorenz S, Radhakrishnan P, Kautz N, Elssner C, Weiss J, Jaeger D, Schneider M, Schulze-Bergkamen H.

BMC Cancer. 2015 Nov 19;15:919. doi: 10.1186/s12885-015-1929-y.


Hypophagia and metabolic adaptations in mice with defective ATGL-mediated lipolysis cause resistance to HFD-induced obesity.

Schreiber R, Hofer P, Taschler U, Voshol PJ, Rechberger GN, Kotzbeck P, Jaeger D, Preiss-Landl K, Lord CC, Brown JM, Haemmerle G, Zimmermann R, Vidal-Puig A, Zechner R.

Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13850-5. doi: 10.1073/pnas.1516004112. Epub 2015 Oct 27.


Mapping the optimal forest road network based on the multicriteria evaluation technique: the case study of Mediterranean Island of Thassos in Greece.

Tampekis S, Sakellariou S, Samara F, Sfougaris A, Jaeger D, Christopoulou O.

Environ Monit Assess. 2015 Nov;187(11):687. doi: 10.1007/s10661-015-4876-9. Epub 2015 Oct 13.



Jaeger DA, Suchan B, Schölmerich A, Schneider DT, Gawehn N.

Infant Ment Health J. 2015 Sep-Oct;36(5):522-30. doi: 10.1002/imhj.21530. Epub 2015 Aug 31.


Effect of stride length on maximal pelvic tilt and hip extension during running.

Dewolf A, De Jaeger D.

Comput Methods Biomech Biomed Engin. 2015;18 Suppl 1:1926-7. doi: 10.1080/10255842.2015.1070582. Epub 2015 Aug 14. No abstract available.


Atomically Traceable Nanostructure Fabrication.

Ballard JB, Dick DD, McDonnell SJ, Bischof M, Fu J, Owen JH, Owen WR, Alexander JD, Jaeger DL, Namboodiri P, Fuchs E, Chabal YJ, Wallace RM, Reidy R, Silver RM, Randall JN, Von Ehr J.

J Vis Exp. 2015 Jul 17;(101):e52900. doi: 10.3791/52900.


Bottom-up assembly of metallic germanium.

Scappucci G, Klesse WM, Yeoh LA, Carter DJ, Warschkow O, Marks NA, Jaeger DL, Capellini G, Simmons MY, Hamilton AR.

Sci Rep. 2015 Aug 10;5:12948. doi: 10.1038/srep12948.

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