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Items: 1 to 50 of 595

1.

Acute Ischemic Stroke with Vessel Occlusion-Prevalence and Thrombectomy Eligibility at a Comprehensive Stroke Center.

Desai SM, Starr M, Molyneaux BJ, Rocha M, Jovin TG, Jadhav AP.

J Stroke Cerebrovasc Dis. 2019 Aug 10:104315. doi: 10.1016/j.jstrokecerebrovasdis.2019.104315. [Epub ahead of print]

PMID:
31409537
2.

Fields on fire: Alternatives to crop residue burning in India.

Shyamsundar P, Springer NP, Tallis H, Polasky S, Jat ML, Sidhu HS, Krishnapriya PP, Skiba N, Ginn W, Ahuja V, Cummins J, Datta I, Dholakia HH, Dixon J, Gerard B, Gupta R, Hellmann J, Jadhav A, Jat HS, Keil A, Ladha JK, Lopez-Ridaura S, Nandrajog SP, Paul S, Ritter A, Sharma PC, Singh R, Singh D, Somanathan R.

Science. 2019 Aug 9;365(6453):536-538. doi: 10.1126/science.aaw4085. No abstract available.

PMID:
31395767
3.

Cadherin-Mediated Cell Coupling Coordinates Chemokine Sensing across Collectively Migrating Cells.

Colak-Champollion T, Lan L, Jadhav AR, Yamaguchi N, Venkiteswaran G, Patel H, Cammer M, Meier-Schellersheim M, Knaut H.

Curr Biol. 2019 Aug 5;29(15):2570-2579.e7. doi: 10.1016/j.cub.2019.06.061.

PMID:
31386838
4.

Noncontrast Computed Tomography Alberta Stroke Program Early CT Score May Modify Intra-Arterial Treatment Effect in DAWN.

Bhuva P, Yoo AJ, Jadhav AP, Jovin TG, Haussen DC, Bonafe A, Budzik RJ, Yavagal DR, Hanel RA, Hassan AE, Ribo M, Cognard C, Sila CA, Morgan PM, Zhang Y, Shields R, Smith W, Saver JL, Liebeskind DS, Nogueira RG; DAWN Trial Investigators.

Stroke. 2019 Jul 26:STROKEAHA118024583. doi: 10.1161/STROKEAHA.118.024583. [Epub ahead of print]

PMID:
31345135
5.

Outcome in Direct Versus Transfer Patients in the DAWN Controlled Trial.

Aghaebrahim A, Jadhav AP, Hanel R, Sauvageau E, Granja MF, Zhang Y, Haussen DC, Budzik RF, Bonafe A, Bhuva P, Ribo M, Cognard C, Sila C, Yavagal D, Hassan AE, Smith WS, Saver J, Liebeskind DS, Nogueira RG, Jovin TG; DAWN Investigators.

Stroke. 2019 Aug;50(8):2163-2167. doi: 10.1161/STROKEAHA.119.025710. Epub 2019 Jul 15.

PMID:
31303153
6.

"Piezosurgery vs bur in impacted mandibular third molar surgery: Evaluation of postoperative sequelae".

Patil C, Jadhav A, K R, Bhola N, Borle RM, Mishra A.

J Oral Biol Craniofac Res. 2019 Jul-Sep;9(3):259-262. doi: 10.1016/j.jobcr.2019.06.007. Epub 2019 Jun 12.

7.

Clinical Comparison of New Generation 0.071-inch and 0.072-inch Aspiration Catheters.

Gross BA, Jadhav AP, Jovin TG, Jankowitz BT.

World Neurosurg. 2019 Jun 25. pii: S1878-8750(19)31672-9. doi: 10.1016/j.wneu.2019.06.120. [Epub ahead of print]

PMID:
31247355
8.

Comparison of Efficiency and Image Quality of Photostimulable Phosphor Plate and Charge-Coupled Device Receptors in Dental Radiography.

Zhang W, Huynh C, Jadhav A, Pinales J, Arvizu L, Tsai J, Flores N.

J Dent Educ. 2019 Jun 24. pii: JDE.019.120. doi: 10.21815/JDE.019.120. [Epub ahead of print]

PMID:
31235501
9.

Prevalence and Temporal Distribution of Fast and Slow Progressors of Infarct Growth in Large Vessel Occlusion Stroke.

Rocha M, Desai SM, Jadhav AP, Jovin TG.

Stroke. 2019 Aug;50(8):2238-2240. doi: 10.1161/STROKEAHA.118.024035. Epub 2019 Jun 17.

PMID:
31203787
10.

General anesthesia vs local anesthesia during mechanical thrombectomy in acute ischemic stroke.

Wu L, Jadhav AP, Zhao W, Wu D, Chen J, Yang S, Wu C, Li C, Duan J, Ding Y, Ji X.

J Neurol Sci. 2019 Aug 15;403:13-18. doi: 10.1016/j.jns.2019.05.034. Epub 2019 May 30.

PMID:
31176193
11.

The NCATS BioPlanet - An Integrated Platform for Exploring the Universe of Cellular Signaling Pathways for Toxicology, Systems Biology, and Chemical Genomics.

Huang R, Grishagin I, Wang Y, Zhao T, Greene J, Obenauer JC, Ngan D, Nguyen DT, Guha R, Jadhav A, Southall N, Simeonov A, Austin CP.

Front Pharmacol. 2019 Apr 26;10:445. doi: 10.3389/fphar.2019.00445. eCollection 2019.

12.

Balloon-mounted stents for acute intracranial large vessel occlusion secondary to presumed atherosclerotic disease: evolution in an era of supple intermediate catheters.

Gross BA, Desai SM, Walker G, Jankowitz BT, Jadhav A, Jovin TG.

J Neurointerv Surg. 2019 May 15. pii: neurintsurg-2019-014877. doi: 10.1136/neurintsurg-2019-014877. [Epub ahead of print]

PMID:
31092560
13.

Is 0.75% ropivacaine more efficacious than 2% lignocaine with 1:80,000 epinephrine for IANB in surgical extraction of impacted lower third molar?

Reddy KV, Jadhav A, Bhola N, Mishra A, Dakshinkar P.

Oral Maxillofac Surg. 2019 Jun;23(2):225-231. doi: 10.1007/s10006-019-00779-w. Epub 2019 May 14.

PMID:
31089895
14.

Indigenously Prepared Ready-to-use Therapeutic Food (RUTF) in Children with Severe Acute Malnutrition.

Jadhav AR, Karnik P, Fernandes L, Fernandes S, Shah N, Manglani M.

Indian Pediatr. 2019 Apr 15;56(4):287-293.

15.

Maturing institutional experience with the transradial approach for diagnostic cerebral arteriography: overcoming the learning curve.

Zussman BM, Tonetti DA, Stone J, Brown M, Desai SM, Gross BA, Jadhav A, Jovin TG, Jankowitz BT.

J Neurointerv Surg. 2019 Apr 27. pii: neurintsurg-2019-014920. doi: 10.1136/neurintsurg-2019-014920. [Epub ahead of print]

PMID:
31030189
16.

An interdisciplinary approach to inhospital stroke improves stroke detection and treatment time.

Manners J, Khandker N, Barron A, Aziz Y, Desai SM, Morrow B, Delfyett WT, Martin-Gill C, Shutter L, Jovin TG, Jadhav AP.

J Neurointerv Surg. 2019 Apr 27. pii: neurintsurg-2019-014890. doi: 10.1136/neurintsurg-2019-014890. [Epub ahead of print]

PMID:
31030187
17.

Molecular targets of biofabricated silver nanoparticles in Candida albicans.

Halbandge SD, Jadhav AK, Jangid PM, Shelar AV, Patil RH, Karuppayil SM.

J Antibiot (Tokyo). 2019 Aug;72(8):640-644. doi: 10.1038/s41429-019-0185-9. Epub 2019 Apr 24.

PMID:
31019258
18.

Acute Stroke Trial Enrollment through a Telemedicine Network: A 12-Year Experience.

Shoirah H, Wechsler LR, Jovin TG, Jadhav AP.

J Stroke Cerebrovasc Dis. 2019 Jul;28(7):1926-1929. doi: 10.1016/j.jstrokecerebrovasdis.2019.03.046. Epub 2019 Apr 20.

PMID:
31010762
19.

Short Course of High-dose Steroids for Anaphylaxis Caused Flare Up of Tuberculosis: A Case Report.

Patil S, Jadhav A.

J Transl Int Med. 2019 Mar 29;7(1):39-42. doi: 10.2478/jtim-2019-0008. eCollection 2019 Mar.

20.

Endovascular Thrombectomy, Platelet Count, and Intracranial Hemorrhage.

Desai SM, Mehta A, Morrison AA, Gross BA, Jankowitz BT, Jovin TG, Jadhav AP.

World Neurosurg. 2019 Jul;127:e1039-e1043. doi: 10.1016/j.wneu.2019.04.036. Epub 2019 Apr 10.

PMID:
30980980
21.

Stentriever salvage after failed manual aspiration thrombectomy.

Tonetti DA, Desai SM, Casillo S, Zussman BM, Jadhav A, Jankowitz BT, Jovin TG, Gross BA.

J Neurointerv Surg. 2019 Aug;11(8):747-750. doi: 10.1136/neurintsurg-2019-014828. Epub 2019 Apr 10.

PMID:
30971424
22.

Angiotensin II in septic shock.

Jadhav AP, Sadaka FG.

Am J Emerg Med. 2019 Jun;37(6):1169-1174. doi: 10.1016/j.ajem.2019.03.026. Epub 2019 Mar 19. Review.

PMID:
30935784
23.

Synthesis and characterization of polylactide/rice husk hydrochar composite.

Nizamuddin S, Jadhav A, Qureshi SS, Baloch HA, Siddiqui MTH, Mubarak NM, Griffin G, Madapusi S, Tanksale A, Ahamed MI.

Sci Rep. 2019 Apr 1;9(1):5445. doi: 10.1038/s41598-019-41960-1.

24.

Lead optimization and efficacy evaluation of quinazoline-based BET family inhibitors for potential treatment of cancer and inflammatory diseases.

Yang SM, Yoshioka M, Strovel JW, Urban DJ, Hu X, Hall MD, Jadhav A, Maloney DJ.

Bioorg Med Chem Lett. 2019 May 15;29(10):1220-1226. doi: 10.1016/j.bmcl.2019.03.014. Epub 2019 Mar 12.

PMID:
30905542
25.

Extravasation control with preserved vessel patency after wire perforation during neurothrombectomy: Case report and literature review.

Moshayedi P, Desai SM, Jadhav AP.

J Clin Neurosci. 2019 Jul;65:151-153. doi: 10.1016/j.jocn.2019.03.024. Epub 2019 Mar 20.

PMID:
30904241
26.

Response by Desai and Jadhav to Letter Regarding Article, "High Variability in Neuronal Loss".

Desai SM, Jadhav AP.

Stroke. 2019 May;50(5):e128. doi: 10.1161/STROKEAHA.119.024939. No abstract available.

PMID:
30890108
27.

A prospective study of the transradial approach for diagnostic cerebral arteriography.

Zussman BM, Tonetti DA, Stone J, Brown M, Desai SM, Gross BA, Jadhav A, Jovin TG, Jankowitz BT.

J Neurointerv Surg. 2019 Mar 6. pii: neurintsurg-2018-014686. doi: 10.1136/neurintsurg-2018-014686. [Epub ahead of print]

PMID:
30842303
28.

Hemodynamic differences between Pipeline and coil-adjunctive intracranial stents.

Jankowitz BT, Gross BA, Seshadhri S, Girdhar G, Jadhav A, Jovin TG, Wainwright JM.

J Neurointerv Surg. 2019 Sep;11(9):908-911. doi: 10.1136/neurintsurg-2018-014439. Epub 2019 Feb 27.

PMID:
30814328
29.

Which Parameters Affect Biofilm Removal with Acoustic Cavitation? A Review.

Vyas N, Manmi K, Wang Q, Jadhav AJ, Barigou M, Sammons RL, Kuehne SA, Walmsley AD.

Ultrasound Med Biol. 2019 May;45(5):1044-1055. doi: 10.1016/j.ultrasmedbio.2019.01.002. Epub 2019 Feb 19. Review.

PMID:
30792088
30.

Glucose Modifies the Effect of Endovascular Thrombectomy in Patients With Acute Stroke.

Chamorro Á, Brown S, Amaro S, Hill MD, Muir KW, Dippel DWJ, van Zwam W, Butcher K, Ford GA, den Hertog HM, Mitchell PJ, Demchuk AM, Majoie CBLM, Bracard S, Sibon I, Jadhav AP, Lara-Rodriguez B, van der Lugt A, Osei E, Renú A, Richard S, Rodriguez-Luna D, Donnan GA, Dixit A, Almekhlafi M, Deltour S, Epstein J, Guillon B, Bakchine S, Gomis M, du Mesnil de Rochemont R, Lopes D, Reddy V, Rudel G, Roos YBWEM, Bonafe A, Diener HC, Berkhemer OA, Cloud GC, Davis SM, van Oostenbrugge R, Guillemin F, Goyal M, Campbell BCV, Menon BK; HERMES Collaborators.

Stroke. 2019 Mar;50(3):690-696. doi: 10.1161/STROKEAHA.118.023769.

PMID:
30777000
31.

Impact of Balloon Guide Catheter Use on Clinical and Angiographic Outcomes in the STRATIS Stroke Thrombectomy Registry.

Zaidat OO, Mueller-Kronast NH, Hassan AE, Haussen DC, Jadhav AP, Froehler MT, Jahan R, Ali Aziz-Sultan M, Klucznik RP, Saver JL, Hellinger FR Jr, Yavagal DR, Yao TL, Gupta R, Martin CO, Bozorgchami H, Kaushal R, Nogueira RG, Gandhi RH, Peterson EC, Dashti S, Given CA 2nd, Mehta BP, Deshmukh V, Starkman S, Linfante I, McPherson SH, Kvamme P, Grobelny TJ, Hussain MS, Thacker I, Vora N, Chen PR, Monteith SJ, Ecker RD, Schirmer CM, Sauvageau E, Chebl AB, Derdeyn CP, Maidan L, Badruddin A, Siddiqui AH, Dumont TM, Alhajeri A, Taqi MA, Asi K, Carpenter J, Boulos A, Jindal G, Puri AS, Chitale R, Deshaies EM, Robinson D, Kallmes DF, Baxter BW, Jumaa M, Sunenshine P, Majjhoo A, English JD, Suzuki S, Fessler RD, Delgado-Almandoz J, Martin JC, Liebeskind DS; STRATIS Investigators.

Stroke. 2019 Mar;50(3):697-704. doi: 10.1161/STROKEAHA.118.021126.

PMID:
30776994
32.

KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.

Hinohara K, Wu HJ, Sébastien Vigneau, McDonald TO, Igarashi KJ, Yamamoto KN, Madsen T, Fassl A, Egri SB, Papanastasiou M, Ding L, Peluffo G, Cohen O, Kales SC, Lal-Nag M, Rai G, Maloney DJ, Jadhav A, Simeonov A, Wagle N, Brown M, Meissner A, Sicinski P, Jaffe JD, Jeselsohn R, Gimelbrant AA, Michor F, Polyak K.

Cancer Cell. 2019 Feb 11;35(2):330-332. doi: 10.1016/j.ccell.2019.01.012. No abstract available.

33.

Large-bore aspiration catheter selection does not influence reperfusion or outcome after manual aspiration thrombectomy.

Tonetti DA, Desai SM, Casillo S, Zussman BM, Brown MW, Jadhav AP, Jankowitz BT, Jovin TG, Gross BA.

J Neurointerv Surg. 2019 Jul;11(7):637-640. doi: 10.1136/neurintsurg-2018-014633. Epub 2019 Feb 7.

PMID:
30733300
34.

Secular Increases in Spontaneous Subarachnoid Hemorrhage during Pregnancy: A Nationwide Sample Analysis.

Limaye K, Patel A, Dave M, Kenmuir C, Lahoti S, Jadhav AP, Samaniego EA, Ortega-Gutièrrez S, Torner J, Hasan D, Derdeyn CP, Jovin T, Adams HP Jr, Leira EC.

J Stroke Cerebrovasc Dis. 2019 Apr;28(4):1141-1148. doi: 10.1016/j.jstrokecerebrovasdis.2019.01.025. Epub 2019 Jan 31.

PMID:
30711414
35.

Pipeline Embolization of an Infectious Basilar Artery Aneurysm in a 2-Year-Old Child: Case Report, Discussion of the Literature and Perioperative Considerations.

Ares WJ, Tonetti DA, Greene S, Sharma MS, Xavier F, Jankowitz BT, Jadhav A.

Oper Neurosurg (Hagerstown). 2019 Jan 23. doi: 10.1093/ons/opz002. [Epub ahead of print]

PMID:
30690548
36.

Validation of an extrinsic compression and early ambulation protocol after diagnostic transfemoral cerebral angiography: a 5-year prospective series.

Tonetti DA, Ferari C, Perez J, Ozpinar A, Jadhav AP, Jovin TG, Gross BA, Jankowitz BT.

J Neurointerv Surg. 2019 Aug;11(8):837-840. doi: 10.1136/neurintsurg-2018-014572. Epub 2019 Jan 23.

PMID:
30674635
37.

Neuroform Atlas Stent System for the treatment of intracranial aneurysm: primary results of the Atlas Humanitarian Device Exemption cohort.

Jankowitz BT, Hanel R, Jadhav AP, Loy DN, Frei D, Siddiqui AH, Puri AS, Khaldi A, Turk AS, Malek AM, Sauvageau E, Hetts SW, Zaidat OO.

J Neurointerv Surg. 2019 Aug;11(8):801-806. doi: 10.1136/neurintsurg-2018-014455. Epub 2019 Jan 22.

PMID:
30670625
38.

Social media and predictors of traditional citations: insights from the Journal of Neurointerventional Surgery.

Jadhav AP, Ducruet AF, de Leacy R, Fargen KM.

J Neurointerv Surg. 2019 Feb;11(2):99-100. doi: 10.1136/neurintsurg-2018-014689. No abstract available.

PMID:
30665984
39.

Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space.

Kearney SE, Zahoránszky-Kőhalmi G, Brimacombe KR, Henderson MJ, Lynch C, Zhao T, Wan KK, Itkin Z, Dillon C, Shen M, Cheff DM, Lee TD, Bougie D, Cheng K, Coussens NP, Dorjsuren D, Eastman RT, Huang R, Iannotti MJ, Karavadhi S, Klumpp-Thomas C, Roth JS, Sakamuru S, Sun W, Titus SA, Yasgar A, Zhang YQ, Zhao J, Andrade RB, Brown MK, Burns NZ, Cha JK, Mevers EE, Clardy J, Clement JA, Crooks PA, Cuny GD, Ganor J, Moreno J, Morrill LA, Picazo E, Susick RB, Garg NK, Goess BC, Grossman RB, Hughes CC, Johnston JN, Joullie MM, Kinghorn AD, Kingston DGI, Krische MJ, Kwon O, Maimone TJ, Majumdar S, Maloney KN, Mohamed E, Murphy BT, Nagorny P, Olson DE, Overman LE, Brown LE, Snyder JK, Porco JA Jr, Rivas F, Ross SA, Sarpong R, Sharma I, Shaw JT, Xu Z, Shen B, Shi W, Stephenson CRJ, Verano AL, Tan DS, Tang Y, Taylor RE, Thomson RJ, Vosburg DA, Wu J, Wuest WM, Zakarian A, Zhang Y, Ren T, Zuo Z, Inglese J, Michael S, Simeonov A, Zheng W, Shinn P, Jadhav A, Boxer MB, Hall MD, Xia M, Guha R, Rohde JM.

ACS Cent Sci. 2018 Dec 26;4(12):1727-1741. doi: 10.1021/acscentsci.8b00747. Epub 2018 Dec 5.

40.

A Multi-Institutional Study to Evaluate Automated Whole Slide Scoring of Immunohistochemistry for Assessment of Programmed Death-Ligand 1 (PD-L1) Expression in Non-Small Cell Lung Cancer.

Taylor CR, Jadhav AP, Gholap A, Kamble G, Huang J, Gown A, Doshi I, Rimm DL.

Appl Immunohistochem Mol Morphol. 2019 Apr;27(4):263-269. doi: 10.1097/PAI.0000000000000737.

PMID:
30640753
41.

Impact of Stent Retriever Size on Clinical and Angiographic Outcomes in the STRATIS Stroke Thrombectomy Registry.

Zaidat OO, Haussen DC, Hassan AE, Jadhav AP, Mehta BP, Mokin M, Mueller-Kronast NH, Froehler MT.

Stroke. 2019 Feb;50(2):441-447. doi: 10.1161/STROKEAHA.118.022987.

PMID:
30626287
42.

A high-throughput screen to identify novel small molecule inhibitors of the Werner Syndrome Helicase-Nuclease (WRN).

Sommers JA, Kulikowicz T, Croteau DL, Dexheimer T, Dorjsuren D, Jadhav A, Maloney DJ, Simeonov A, Bohr VA, Brosh RM Jr.

PLoS One. 2019 Jan 9;14(1):e0210525. doi: 10.1371/journal.pone.0210525. eCollection 2019.

43.

Infarct Volume Predicts Hospitalization Costs in Anterior Circulation Large-Vessel Occlusion Stroke.

Streib CD, Rangaraju S, Campbell DT, Winger DG, Paolini SL, Zhang AJ, Jankowitz BT, Jadhav AP, Jovin TG.

AJNR Am J Neuroradiol. 2019 Jan;40(1):51-58. doi: 10.3174/ajnr.A5917. Epub 2018 Dec 27.

44.

Emergent Management of Tandem Lesions in Acute Ischemic Stroke.

Jadhav AP, Zaidat OO, Liebeskind DS, Yavagal DR, Haussen DC, Hellinger FR Jr, Jahan R, Jumaa MA, Szeder V, Nogueira RG, Jovin TG.

Stroke. 2019 Feb;50(2):428-433. doi: 10.1161/STROKEAHA.118.021893.

PMID:
30580729
45.

Endovascular Recanalization of Symptomatic Intracranial Arterial Stenosis Despite Aggressive Medical Management.

Aghaebrahim A, Agnoletto GJ, Aguilar-Salinas P, Granja MF, Monteiro A, Siddiqui AH, Levy EI, Shallwani H, Kim SJ, Haussen DC, Nogueira RG, Lopes D, Saied A, Jovin TG, Jadhav AP, Limaye K, Turk AS, Spiotta AM, Chaudry MI, Turner RD, Brasiliense LBC, Dumont TM, Cherian J, Kan P, Sauvageau E, Hanel RA.

World Neurosurg. 2019 Mar;123:e693-e699. doi: 10.1016/j.wneu.2018.12.008. Epub 2018 Dec 18.

PMID:
30576811
46.

High Variability in Neuronal Loss.

Desai SM, Rocha M, Jovin TG, Jadhav AP.

Stroke. 2019 Jan;50(1):34-37. doi: 10.1161/STROKEAHA.118.023499.

PMID:
30566036
47.

Ruptured intracranial aneurysm in a patient with autosomal recessive polycystic kidney disease.

Perez JL, McDowell MM, Zussman B, Jadhav AP, Miyashita Y, McKiernan P, Greene S.

J Neurosurg Pediatr. 2018 Oct 12;23(1):75-79. doi: 10.3171/2018.8.PEDS18286.

PMID:
30497224
48.

Molecular basis for activation of lecithin:cholesterol acyltransferase by a compound that increases HDL cholesterol.

Manthei KA, Yang SM, Baljinnyam B, Chang L, Glukhova A, Yuan W, Freeman LA, Maloney DJ, Schwendeman A, Remaley AT, Jadhav A, Tesmer JJ.

Elife. 2018 Nov 27;7. pii: e41604. doi: 10.7554/eLife.41604.

49.

KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.

Hinohara K, Wu HJ, Vigneau S, McDonald TO, Igarashi KJ, Yamamoto KN, Madsen T, Fassl A, Egri SB, Papanastasiou M, Ding L, Peluffo G, Cohen O, Kales SC, Lal-Nag M, Rai G, Maloney DJ, Jadhav A, Simeonov A, Wagle N, Brown M, Meissner A, Sicinski P, Jaffe JD, Jeselsohn R, Gimelbrant AA, Michor F, Polyak K.

Cancer Cell. 2018 Dec 10;34(6):939-953.e9. doi: 10.1016/j.ccell.2018.10.014. Epub 2018 Nov 21. Erratum in: Cancer Cell. 2019 Feb 11;35(2):330-332.

PMID:
30472020
50.

Final Results of the RHAPSODY Trial: A Multi-Center, Phase 2 Trial Using a Continual Reassessment Method to Determine the Safety and Tolerability of 3K3A-APC, A Recombinant Variant of Human Activated Protein C, in Combination with Tissue Plasminogen Activator, Mechanical Thrombectomy or both in Moderate to Severe Acute Ischemic Stroke.

Lyden P, Pryor KE, Coffey CS, Cudkowicz M, Conwit R, Jadhav A, Sawyer RN Jr, Claassen J, Adeoye O, Song S, Hannon P, Rost NS, Hinduja A, Torbey M, Lee JM, Benesch C, Rippee M, Rymer M, Froehler MT, Clarke Haley E, Johnson M, Yankey J, Magee K, Qidwai J, Levy H, Mark Haacke E, Fawaz M, Davis TP, Toga AW, Griffin JH, Zlokovic BV; NeuroNEXT Clinical Trials Network NN104 Investigators.

Ann Neurol. 2019 Jan;85(1):125-136. doi: 10.1002/ana.25383. Epub 2019 Jan 7.

PMID:
30450637

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