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Items: 17


Grandmaster level in StarCraft II using multi-agent reinforcement learning.

Vinyals O, Babuschkin I, Czarnecki WM, Mathieu M, Dudzik A, Chung J, Choi DH, Powell R, Ewalds T, Georgiev P, Oh J, Horgan D, Kroiss M, Danihelka I, Huang A, Sifre L, Cai T, Agapiou JP, Jaderberg M, Vezhnevets AS, Leblond R, Pohlen T, Dalibard V, Budden D, Sulsky Y, Molloy J, Paine TL, Gulcehre C, Wang Z, Pfaff T, Wu Y, Ring R, Yogatama D, Wünsch D, McKinney K, Smith O, Schaul T, Lillicrap T, Kavukcuoglu K, Hassabis D, Apps C, Silver D.

Nature. 2019 Oct 30. doi: 10.1038/s41586-019-1724-z. [Epub ahead of print]


Human-level performance in 3D multiplayer games with population-based reinforcement learning.

Jaderberg M, Czarnecki WM, Dunning I, Marris L, Lever G, Castañeda AG, Beattie C, Rabinowitz NC, Morcos AS, Ruderman A, Sonnerat N, Green T, Deason L, Leibo JZ, Silver D, Hassabis D, Kavukcuoglu K, Graepel T.

Science. 2019 May 31;364(6443):859-865. doi: 10.1126/science.aau6249.


Abscopal effect when combining oncolytic adenovirus and checkpoint inhibitor in a humanized NOG mouse model of melanoma.

Kuryk L, Møller AW, Jaderberg M.

J Med Virol. 2019 Sep;91(9):1702-1706. doi: 10.1002/jmv.25501. Epub 2019 Jun 24.


Combination of immunogenic oncolytic adenovirus ONCOS-102 with anti-PD-1 pembrolizumab exhibits synergistic antitumor effect in humanized A2058 melanoma huNOG mouse model.

Kuryk L, Møller AW, Jaderberg M.

Oncoimmunology. 2018 Oct 29;8(2):e1532763. doi: 10.1080/2162402X.2018.1532763. eCollection 2019.


Optimization of Early Steps in Oncolytic Adenovirus ONCOS-401 Production in T-175 and HYPERFlasks.

Kuryk L, Møller AW, Vuolanto A, Pesonen S, Garofalo M, Cerullo V, Jaderberg M.

Int J Mol Sci. 2019 Jan 31;20(3). pii: E621. doi: 10.3390/ijms20030621.


Quantification and functional evaluation of CD40L production from the adenovirus vector ONCOS-401.

Kuryk L, Møller AW, Jaderberg M.

Cancer Gene Ther. 2019 Feb;26(1-2):26-31. doi: 10.1038/s41417-018-0038-x. Epub 2018 Jul 30.


Antitumor-specific T-cell responses induced by oncolytic adenovirus ONCOS-102 (AdV5/3-D24-GM-CSF) in peritoneal mesothelioma mouse model.

Kuryk L, Møller AW, Garofalo M, Cerullo V, Pesonen S, Alemany R, Jaderberg M.

J Med Virol. 2018 Oct;90(10):1669-1673. doi: 10.1002/jmv.25229. Epub 2018 Jun 11.


Phase I study with ONCOS-102 for the treatment of solid tumors - an evaluation of clinical response and exploratory analyses of immune markers.

Ranki T, Pesonen S, Hemminki A, Partanen K, Kairemo K, Alanko T, Lundin J, Linder N, Turkki R, Ristimäki A, Jäger E, Karbach J, Wahle C, Kankainen M, Backman C, von Euler M, Haavisto E, Hakonen T, Heiskanen R, Jaderberg M, Juhila J, Priha P, Suoranta L, Vassilev L, Vuolanto A, Joensuu T.

J Immunother Cancer. 2016 Mar 15;4:17. doi: 10.1186/s40425-016-0121-5. eCollection 2016.


Repeated intratumoral administration of ONCOS-102 leads to systemic antitumor CD8+ T-cell response and robust cellular and transcriptional immune activation at tumor site in a patient with ovarian cancer.

Vassilev L, Ranki T, Joensuu T, Jäger E, Karbach J, Wahle C, Partanen K, Kairemo K, Alanko T, Turkki R, Linder N, Lundin J, Ristimäki A, Kankainen M, Hemminki A, Backman C, Dienel K, von Euler M, Haavisto E, Hakonen T, Juhila J, Jäderberg M, Priha P, Vuolanto A, Pesonen S.

Oncoimmunology. 2015 Apr 1;4(7):e1017702. eCollection 2015 Jul.


Local treatment of a pleural mesothelioma tumor with ONCOS-102 induces a systemic antitumor CD8+ T-cell response, prominent infiltration of CD8+ lymphocytes and Th1 type polarization.

Ranki T, Joensuu T, Jäger E, Karbach J, Wahle C, Kairemo K, Alanko T, Partanen K, Turkki R, Linder N, Lundin J, Ristimäki A, Kankainen M, Hemminki A, Backman C, Dienel K, von Euler M, Haavisto E, Hakonen T, Juhila J, Jaderberg M, Priha P, Vassilev L, Vuolanto A, Pesonen S.

Oncoimmunology. 2014 Dec 15;3(10):e958937. eCollection 2014 Nov.


The cost effectiveness of amoxicillin/clavulanic acid as antibacterial prophylaxis in abdominal and gynaecological surgery.

Davey PG, Parker SE, Crombie IK, Jaderberg M.

Pharmacoeconomics. 1995 Apr;7(4):347-56.


A meta-analysis of the use of amoxycillin-clavulanic acid in surgical prophylaxis.

Wilson AP, Shrimpton S, Jaderberg M.

J Hosp Infect. 1992 Nov;22 Suppl A:9-21.


A comparison of the costs of ceftazidime therapy and gentamicin combinations in three UK hospitals.

Malek M, Lynch W, Wells N, Elliott T, Bint A, Sanderson P, Jaderberg M, Davey P.

J Antimicrob Chemother. 1992 Feb;29(2):207-17.


Comparison of minimal and conventional surgery in patients with bleeding peptic ulcer: a multicentre trial.

Poxon VA, Keighley MR, Dykes PW, Heppinstall K, Jaderberg M.

Br J Surg. 1991 Nov;78(11):1344-5.


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