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Items: 1 to 50 of 66

1.

Nicotinamide riboside, a form of vitamin B3, protects against excitotoxicity-induced axonal degeneration.

Vaur P, Brugg B, Mericskay M, Li Z, Schmidt MS, Vivien D, Orset C, Jacotot E, Brenner C, Duplus E.

FASEB J. 2017 Dec;31(12):5440-5452. doi: 10.1096/fj.201700221RR. Epub 2017 Aug 21.

PMID:
28842432
2.

β-amyloid induces a dying-back process and remote trans-synaptic alterations in a microfluidic-based reconstructed neuronal network.

Deleglise B, Magnifico S, Duplus E, Vaur P, Soubeyre V, Belle M, Vignes M, Viovy JL, Jacotot E, Peyrin JM, Brugg B.

Acta Neuropathol Commun. 2014 Sep 25;2:145. doi: 10.1186/s40478-014-0145-3.

3.

Molecular monitoring of the bacterial community structure in foal feces pre- and post-weaning.

Faubladier C, Sadet-Bourgeteau S, Philippeau C, Jacotot E, Julliand V.

Anaerobe. 2014 Feb;25:61-6. doi: 10.1016/j.anaerobe.2013.11.010. Epub 2013 Dec 4.

PMID:
24315809
4.

Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro.

Chhor V, Le Charpentier T, Lebon S, Oré MV, Celador IL, Josserand J, Degos V, Jacotot E, Hagberg H, Sävman K, Mallard C, Gressens P, Fleiss B.

Brain Behav Immun. 2013 Aug;32:70-85. doi: 10.1016/j.bbi.2013.02.005. Epub 2013 Feb 27.

5.

Mitochondria and cytoprotection.

Brenner C, Ventura-Clapier R, Jacotot E.

Biochem Res Int. 2012;2012:351264. doi: 10.1155/2012/351264. Epub 2012 Aug 16. No abstract available.

6.

HIV-1 Tat protein directly induces mitochondrial membrane permeabilization and inactivates cytochrome c oxidase.

Lecoeur H, Borgne-Sanchez A, Chaloin O, El-Khoury R, Brabant M, Langonné A, Porceddu M, Brière JJ, Buron N, Rebouillat D, Péchoux C, Deniaud A, Brenner C, Briand JP, Muller S, Rustin P, Jacotot E.

Cell Death Dis. 2012 Mar 15;3:e282. doi: 10.1038/cddis.2012.21.

7.

Combined effect of hypothermia and caspase-2 gene deficiency on neonatal hypoxic-ischemic brain injury.

Carlsson Y, Wang X, Schwendimann L, Rousset CI, Jacotot E, Gressens P, Thoresen M, Mallard C, Hagberg H.

Pediatr Res. 2012 May;71(5):566-72. doi: 10.1038/pr.2012.15. Epub 2012 Feb 9.

PMID:
22322383
8.

Prevention of neonatal oxygen-induced brain damage by reduction of intrinsic apoptosis.

Sifringer M, Bendix I, Börner C, Endesfelder S, von Haefen C, Kalb A, Holifanjaniaina S, Prager S, Schlager GW, Keller M, Jacotot E, Felderhoff-Mueser U.

Cell Death Dis. 2012 Jan 12;3:e250. doi: 10.1038/cddis.2011.133.

9.

Isolation of brain mitochondria from neonatal mice.

Wang X, Leverin AL, Han W, Zhu C, Johansson BR, Jacotot E, Ten VS, Sims NR, Hagberg H.

J Neurochem. 2011 Dec;119(6):1253-61. doi: 10.1111/j.1471-4159.2011.07525.x. Epub 2011 Nov 3.

10.

Targeting neonatal ischemic brain injury with a pentapeptide-based irreversible caspase inhibitor.

Chauvier D, Renolleau S, Holifanjaniaina S, Ankri S, Bezault M, Schwendimann L, Rousset C, Casimir R, Hoebeke J, Smirnova M, Debret G, Trichet AP, Carlsson Y, Wang X, Bernard E, Hébert M, Rauzier JM, Matecki S, Lacampagne A, Rustin P, Mariani J, Hagberg H, Gressens P, Charriaut-Marlangue C, Jacotot E.

Cell Death Dis. 2011 Sep 1;2:e203. doi: 10.1038/cddis.2011.87.

11.

Ryanodine receptor leak mediated by caspase-8 activation leads to left ventricular injury after myocardial ischemia-reperfusion.

Fauconnier J, Meli AC, Thireau J, Roberge S, Shan J, Sassi Y, Reiken SR, Rauzier JM, Marchand A, Chauvier D, Cassan C, Crozier C, Bideaux P, Lompré AM, Jacotot E, Marks AR, Lacampagne A.

Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13258-63. doi: 10.1073/pnas.1100286108. Epub 2011 Jul 25.

12.

Genetic inhibition of caspase-2 reduces hypoxic-ischemic and excitotoxic neonatal brain injury.

Carlsson Y, Schwendimann L, Vontell R, Rousset CI, Wang X, Lebon S, Charriaut-Marlangue C, Supramaniam V, Hagberg H, Gressens P, Jacotot E.

Ann Neurol. 2011 Nov;70(5):781-9. doi: 10.1002/ana.22431. Epub 2011 Jun 14.

PMID:
21674587
13.

Neuroprotective effect of Bax-inhibiting peptide on neonatal brain injury.

Wang X, Han W, Du X, Zhu C, Carlsson Y, Mallard C, Jacotot E, Hagberg H.

Stroke. 2010 Sep;41(9):2050-5. doi: 10.1161/STROKEAHA.110.589051. Epub 2010 Jul 29.

PMID:
20671246
14.

Use of human cancer cell lines mitochondria to explore the mechanisms of BH3 peptides and ABT-737-induced mitochondrial membrane permeabilization.

Buron N, Porceddu M, Brabant M, Desgué D, Racoeur C, Lassalle M, Péchoux C, Rustin P, Jacotot E, Borgne-Sanchez A.

PLoS One. 2010 Mar 31;5(3):e9924. doi: 10.1371/journal.pone.0009924.

15.

Predicting sensorimotor and memory deficits after neonatal ischemic stroke with reperfusion in the rat.

Bouet V, Freret T, Ankri S, Bezault M, Renolleau S, Boulouard M, Jacotot E, Chauvier D, Schumann-Bard P.

Behav Brain Res. 2010 Sep 1;212(1):56-63. doi: 10.1016/j.bbr.2010.03.043. Epub 2010 Mar 27.

PMID:
20347879
16.

The fourth isoform of the adenine nucleotide translocator inhibits mitochondrial apoptosis in cancer cells.

Gallerne C, Touat Z, Chen ZX, Martel C, Mayola E, Sharaf el dein O, Buron N, Le Bras M, Jacotot E, Borgne-Sanchez A, Lemoine A, Lemaire C, Pervaiz S, Brenner C.

Int J Biochem Cell Biol. 2010 May;42(5):623-9. doi: 10.1016/j.biocel.2009.12.024. Epub 2010 Jan 10.

PMID:
20060930
17.

A flavivirus protein M-derived peptide directly permeabilizes mitochondrial membranes, triggers cell death and reduces human tumor growth in nude mice.

Brabant M, Baux L, Casimir R, Briand JP, Chaloin O, Porceddu M, Buron N, Chauvier D, Lassalle M, Lecoeur H, Langonné A, Dupont S, Déas O, Brenner C, Rebouillat D, Muller S, Borgne-Sanchez A, Jacotot E.

Apoptosis. 2009 Oct;14(10):1190-203. doi: 10.1007/s10495-009-0394-y.

PMID:
19693674
18.

Pharmacological screening and enzymatic assays for apoptosis.

Belzacq-Casagrande AS, Martel C, Pertuiset C, Borgne-Sanchez A, Jacotot E, Brenner C.

Front Biosci (Landmark Ed). 2009 Jan 1;14:3550-62.

PMID:
19273292
19.

A critical role for Fas/CD-95 dependent signaling pathways in the pathogenesis of hyperoxia-induced brain injury.

Dzietko M, Boos V, Sifringer M, Polley O, Gerstner B, Genz K, Endesfelder S, Börner C, Jacotot E, Chauvier D, Obladen M, Bührer C, Felderhoff-Mueser U.

Ann Neurol. 2008 Dec;64(6):664-73. doi: 10.1002/ana.21516.

PMID:
19107989
20.

Peptido-targeting of the mitochondrial transition pore complex for therapeutic apoptosis induction.

Deniaud A, Hoebeke J, Briand JP, Muller S, Jacotot E, Brenner C.

Curr Pharm Des. 2006;12(34):4501-11. Review.

PMID:
17168756
21.

Specific caspase inhibitor Q-VD-OPh prevents neonatal stroke in P7 rat: a role for gender.

Renolleau S, Fau S, Goyenvalle C, Joly LM, Chauvier D, Jacotot E, Mariani J, Charriaut-Marlangue C.

J Neurochem. 2007 Feb;100(4):1062-71. Epub 2006 Dec 12.

22.

Broad-spectrum caspase inhibitors: from myth to reality?

Chauvier D, Ankri S, Charriaut-Marlangue C, Casimir R, Jacotot E.

Cell Death Differ. 2007 Feb;14(2):387-91. Epub 2006 Sep 29. No abstract available.

23.

Chemosensitization by knockdown of adenine nucleotide translocase-2.

Le Bras M, Borgne-Sanchez A, Touat Z, El Dein OS, Deniaud A, Maillier E, Lecellier G, Rebouillat D, Lemaire C, Kroemer G, Jacotot E, Brenner C.

Cancer Res. 2006 Sep 15;66(18):9143-52.

24.

Therapeutic peptides: Targeting the mitochondrion to modulate apoptosis.

Jacotot E, Deniaud A, Borgne-Sanchez A, Touat Z, Briand JP, Le Bras M, Brenner C.

Biochim Biophys Acta. 2006 Sep-Oct;1757(9-10):1312-23. Epub 2006 Jul 14. Review.

25.

Targeted Vpr-derived peptides reach mitochondria to induce apoptosis of alphaVbeta3-expressing endothelial cells.

Borgne-Sanchez A, Dupont S, Langonné A, Baux L, Lecoeur H, Chauvier D, Lassalle M, Déas O, Brière JJ, Brabant M, Roux P, Péchoux C, Briand JP, Hoebeke J, Deniaud A, Brenner C, Rustin P, Edelman L, Rebouillat D, Jacotot E.

Cell Death Differ. 2007 Mar;14(3):422-35. Epub 2006 Aug 4.

26.

Upstream control of apoptosis by caspase-2 in serum-deprived primary neurons.

Chauvier D, Lecoeur H, Langonné A, Borgne-Sanchez A, Mariani J, Martinou JC, Rebouillat D, Jacotot E.

Apoptosis. 2005 Dec;10(6):1243-59.

PMID:
16215683
27.

Dynamic analysis of apoptosis in primary cortical neurons by fixed- and real-time cytofluorometry.

Lecoeur H, Chauvier D, Langonné A, Rebouillat D, Brugg B, Mariani J, Edelman L, Jacotot E.

Apoptosis. 2004 Mar;9(2):157-69.

PMID:
15004513
28.

Real-time flow cytometry analysis of permeability transition in isolated mitochondria.

Lecoeur H, Langonné A, Baux L, Rebouillat D, Rustin P, Prévost MC, Brenner C, Edelman L, Jacotot E.

Exp Cell Res. 2004 Mar 10;294(1):106-17.

PMID:
14980506
29.

Palmitate induces apoptosis via a direct effect on mitochondria.

de Pablo MA, Susin SA, Jacotot E, Larochette N, Costantini P, Ravagnan L, Zamzami N, Kroemer G.

Apoptosis. 1999 Apr;4(2):81-7.

PMID:
14634285
30.

Combined use of radioimagers and radioactive 3'OH DNA nick end labelling to quantify apoptosis in cell lines and tissue sections: applications to virus-induced apoptosis.

Jacotot E, Cardona A, Rebouillat D, Terradillos O, Marianneau P, Thoulouze MI, Lafon M, Deubel V, Edelman L.

Apoptosis. 1999 Jun;4(3):169-78.

PMID:
14634279
31.

Cell-surface-expressed HIV-1 envelope induces the death of CD4 T cells during GP41-mediated hemifusion-like events.

Blanco J, Barretina J, Ferri KF, Jacotot E, Gutiérrez A, Armand-Ugón M, Cabrera C, Kroemer G, Clotet B, Esté JA.

Virology. 2003 Jan 20;305(2):318-29.

33.

The anti-HIV pentameric pseudopeptide HB-19 is preferentially taken up in vivo by lymphoid organs where it forms a complex with nucleolin.

Krust B, Vienet R, Cardona A, Rougeot C, Jacotot E, Callebaut C, Guichard G, Briand JP, Grognet JM, Hovanessian AG, Edelman L.

Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):14090-5. Epub 2001 Nov 6.

34.

The adenine nucleotide translocator: a target of nitric oxide, peroxynitrite, and 4-hydroxynonenal.

Vieira HL, Belzacq AS, Haouzi D, Bernassola F, Cohen I, Jacotot E, Ferri KF, El Hamel C, Bartle LM, Melino G, Brenner C, Goldmacher V, Kroemer G.

Oncogene. 2001 Jul 19;20(32):4305-16.

PMID:
11466611
35.

Apoptosis and karyogamy in syncytia induced by the HIV-1-envelope glycoprotein complex.

Ferri KF, Jacotot E, Geuskens M, Kroemer G.

Cell Death Differ. 2000 Nov;7(11):1137-9. No abstract available.

36.

Apoptosis induction by the photosensitizer verteporfin: identification of mitochondrial adenine nucleotide translocator as a critical target.

Belzacq AS, Jacotot E, Vieira HL, Mistro D, Granville DJ, Xie Z, Reed JC, Kroemer G, Brenner C.

Cancer Res. 2001 Feb 15;61(4):1260-4.

37.

Mitochondrial control of cell death induced by HIV-1-encoded proteins.

Ferri KF, Jacotot E, Blanco J, Esté JA, Kroemer G.

Ann N Y Acad Sci. 2000;926:149-64. Review.

PMID:
11193032
38.

Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2.

Jacotot E, Ferri KF, El Hamel C, Brenner C, Druillennec S, Hoebeke J, Rustin P, Métivier D, Lenoir C, Geuskens M, Vieira HL, Loeffler M, Belzacq AS, Briand JP, Zamzami N, Edelman L, Xie ZH, Reed JC, Roques BP, Kroemer G.

J Exp Med. 2001 Feb 19;193(4):509-19.

39.

Permeabilization of the mitochondrial inner membrane during apoptosis: impact of the adenine nucleotide translocator.

Vieira HL, Haouzi D, El Hamel C, Jacotot E, Belzacq AS, Brenner C, Kroemer G.

Cell Death Differ. 2000 Dec;7(12):1146-54. Review.

40.

Apoptosis of syncytia induced by the HIV-1-envelope glycoprotein complex: influence of cell shape and size.

Ferri KF, Jacotot E, Leduc P, Geuskens M, Ingber DE, Kroemer G.

Exp Cell Res. 2000 Nov 25;261(1):119-26.

PMID:
11082282
41.

Apoptosis control in syncytia induced by the HIV type 1-envelope glycoprotein complex: role of mitochondria and caspases.

Ferri KF, Jacotot E, Blanco J, Esté JA, Zamzami N, Susin SA, Xie Z, Brothers G, Reed JC, Penninger JM, Kroemer G.

J Exp Med. 2000 Oct 16;192(8):1081-92.

42.

Mitochondrion as a novel target of anticancer chemotherapy.

Costantini P, Jacotot E, Decaudin D, Kroemer G.

J Natl Cancer Inst. 2000 Jul 5;92(13):1042-53. Review.

PMID:
10880547
43.

Apoptosis and cell cycle: distinct checkpoints with overlapping upstream control.

Jacotot E, Ferri KF, Kroemer G.

Pathol Biol (Paris). 2000 Apr;48(3):271-9. Review.

PMID:
10858959
44.

Mitochondrial membrane permeabilization during the apoptotic process.

Jacotot E, Costantini P, Laboureau E, Zamzami N, Susin SA, Kroemer G.

Ann N Y Acad Sci. 1999;887:18-30. Review.

PMID:
10668461
45.

The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore.

Jacotot E, Ravagnan L, Loeffler M, Ferri KF, Vieira HL, Zamzami N, Costantini P, Druillennec S, Hoebeke J, Briand JP, Irinopoulou T, Daugas E, Susin SA, Cointe D, Xie ZH, Reed JC, Roques BP, Kroemer G.

J Exp Med. 2000 Jan 3;191(1):33-46.

46.

The implication of the chemokine receptor CXCR4 in HIV-1 envelope protein-induced apoptosis is independent of the G protein-mediated signalling.

Blanco J, Jacotot E, Cabrera C, Cardona A, Clotet B, De Clercq E, Esté JA.

AIDS. 1999 May 28;13(8):909-17.

PMID:
10371171
47.

Arsenite induces apoptosis via a direct effect on the mitochondrial permeability transition pore.

Larochette N, Decaudin D, Jacotot E, Brenner C, Marzo I, Susin SA, Zamzami N, Xie Z, Reed J, Kroemer G.

Exp Cell Res. 1999 Jun 15;249(2):413-21.

PMID:
10366441
48.

Molecular characterization of mitochondrial apoptosis-inducing factor.

Susin SA, Lorenzo HK, Zamzami N, Marzo I, Snow BE, Brothers GM, Mangion J, Jacotot E, Costantini P, Loeffler M, Larochette N, Goodlett DR, Aebersold R, Siderovski DP, Penninger JM, Kroemer G.

Nature. 1999 Feb 4;397(6718):441-6.

PMID:
9989411
49.

Dipeptidyl-peptidase IV-beta--further characterization and comparison to dipeptidyl-peptidase IV activity of CD26.

Blanco J, Nguyen C, Callebaut C, Jacotot E, Krust B, Mazaleyrat JP, Wakselman M, Hovanessian AG.

Eur J Biochem. 1998 Sep 1;256(2):369-78.

50.

Identification of V3 loop-binding proteins as potential receptors implicated in the binding of HIV particles to CD4(+) cells.

Callebaut C, Blanco J, Benkirane N, Krust B, Jacotot E, Guichard G, Seddiki N, Svab J, Dam E, Muller S, Briand JP, Hovanessian AG.

J Biol Chem. 1998 Aug 21;273(34):21988-97.

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