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Acute Myeloid Leukemia, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology.

Tallman MS, Wang ES, Altman JK, Appelbaum FR, Bhatt VR, Bixby D, Coutre SE, De Lima M, Fathi AT, Fiorella M, Foran JM, Hall AC, Jacoby M, Lancet J, LeBlanc TW, Mannis G, Marcucci G, Martin MG, Mims A, O'Donnell MR, Olin R, Peker D, Perl A, Pollyea DA, Pratz K, Prebet T, Ravandi F, Shami PJ, Stone RM, Strickland SA, Wieduwilt M, Gregory KM; OCN, Hammond L, Ogba N.

J Natl Compr Canc Netw. 2019 Jun 1;17(6):721-749. doi: 10.6004/jnccn.2019.0028.


Identifying Molecular Markers of Relapse in Myelodysplastic Syndrome.

Jacoby MA, Walter M.

Oncology (Williston Park). 2018 Dec 17;32(12):627-9. No abstract available.


Patient Body Mass Index and Physician Radiation Dose During Coronary Angiography.

Madder RD, VanOosterhout S, Mulder A, Ten Brock T, Clarey AT, Parker JL, Jacoby ME.

Circ Cardiovasc Interv. 2019 Jan;12(1):e006823. doi: 10.1161/CIRCINTERVENTIONS.118.006823.


Mutation Clearance after Transplantation for Myelodysplastic Syndrome.

Jacoby MA, Trinkaus K, Walter MJ.

N Engl J Med. 2018 Dec 13;379(24):2380. doi: 10.1056/NEJMc1813470. No abstract available.


Exome analysis of treatment-related AML after APL suggests secondary evolution.

Wang T, Jacoby MA, Duncavage EJ, Miller CA, Heath S, Rahme R, Fenaux P, Ades L, Renneville A, Cassinat B, Takeshita A, Asou N, Miyazaki Y, Kiyoi H, Ravandi F, Westervelt P, Wartman LD, Welch JS.

Br J Haematol. 2019 Jun;185(5):984-987. doi: 10.1111/bjh.15681. Epub 2018 Nov 22. No abstract available.


Mutation Clearance after Transplantation for Myelodysplastic Syndrome.

Duncavage EJ, Jacoby MA, Chang GS, Miller CA, Edwin N, Shao J, Elliott K, Robinson J, Abel H, Fulton RS, Fronick CC, O'Laughlin M, Heath SE, Brendel K, Saba R, Wartman LD, Christopher MJ, Pusic I, Welch JS, Uy GL, Link DC, DiPersio JF, Westervelt P, Ley TJ, Trinkaus K, Graubert TA, Walter MJ.

N Engl J Med. 2018 Sep 13;379(11):1028-1041. doi: 10.1056/NEJMoa1804714.


Impact of patient obesity on radiation doses received by scrub technologists during coronary angiography.

Refahiyat L, VanOosterhout S, Mulder A, Ten Brock T, Parker JL, Negash A, Jacoby ME, Madder RD.

Cardiovasc Revasc Med. 2018 Dec;19(8):929-933. doi: 10.1016/j.carrev.2018.07.026. Epub 2018 Jul 29.


Anesthesia for Pygopagus Conjoined Twins During Single-Twin and Simultaneous Pneumoperitoneum: A Case Report.

Sara JP, Kydes A, Pryjdun O, Jacoby M, McBride W, Pandya S, Barst S.

A A Pract. 2018 Aug 1;11(3):71-72. doi: 10.1213/XAA.0000000000000739.


Subclones dominate at MDS progression following allogeneic hematopoietic cell transplant.

Jacoby MA, Duncavage EJ, Chang GS, Miller CA, Shao J, Elliott K, Robinson J, Fulton RS, Fronick CC, O'Laughlin M, Heath SE, Pusic I, Welch JS, Link DC, DiPersio JF, Westervelt P, Ley TJ, Graubert TA, Walter MJ.

JCI Insight. 2018 Mar 8;3(5). pii: 98962. doi: 10.1172/jci.insight.98962.


Spontaneous dissection of the left main coronary artery: Case report and brief review.

Veerasamy M, Jacoby ME, Madder RD.

Cardiovasc Revasc Med. 2018 Apr - May;19(3 Pt B):380-383. doi: 10.1016/j.carrev.2017.12.008. Epub 2017 Dec 23. No abstract available.


Safety and efficacy of selinexor in relapsed or refractory multiple myeloma and Waldenstrom macroglobulinemia.

Chen C, Siegel D, Gutierrez M, Jacoby M, Hofmeister CC, Gabrail N, Baz R, Mau-Sorensen M, Berdeja JG, Savona M, Savoie L, Trudel S, Areethamsirikul N, Unger TJ, Rashal T, Hanke T, Kauffman M, Shacham S, Reece D.

Blood. 2018 Feb 22;131(8):855-863. doi: 10.1182/blood-2017-08-797886. Epub 2017 Dec 4.


Radiation Exposure Among Scrub Technologists and Nurse Circulators During Cardiac Catheterization: The Impact of Accessory Lead Shields.

Madder RD, LaCombe A, VanOosterhout S, Mulder A, Elmore M, Parker JL, Jacoby ME, Wohns D.

JACC Cardiovasc Interv. 2018 Jan 22;11(2):206-212. doi: 10.1016/j.jcin.2017.07.026. Epub 2017 Nov 1.


Patterns of infectious complications in acute myeloid leukemia and myelodysplastic syndromes patients treated with 10-day decitabine regimen.

Ali AM, Weisel D, Gao F, Uy GL, Cashen AF, Jacoby MA, Wartman LD, Ghobadi A, Pusic I, Romee R, Fehniger TA, Stockerl-Goldstein KE, Vij R, Oh ST, Abboud CN, Schroeder MA, Westervelt P, DiPersio JF, Welch JS.

Cancer Med. 2017 Dec;6(12):2814-2821. doi: 10.1002/cam4.1231. Epub 2017 Oct 23.


Selective inhibition of nuclear export with selinexor in patients with non-Hodgkin lymphoma.

Kuruvilla J, Savona M, Baz R, Mau-Sorensen PM, Gabrail N, Garzon R, Stone R, Wang M, Savoie L, Martin P, Flinn I, Jacoby M, Unger TJ, Saint-Martin JR, Rashal T, Friedlander S, Carlson R, Kauffman M, Shacham S, Gutierrez M.

Blood. 2017 Jun 15;129(24):3175-3183. doi: 10.1182/blood-2016-11-750174. Epub 2017 May 3.


A phase 1/2 study of chemosensitization with plerixafor plus G-CSF in relapsed or refractory acute myeloid leukemia.

Uy GL, Rettig MP, Stone RM, Konopleva MY, Andreeff M, McFarland K, Shannon W, Fletcher TR, Reineck T, Eades W, Stockerl-Goldstein K, Abboud CN, Jacoby MA, Westervelt P, DiPersio JF.

Blood Cancer J. 2017 Mar 10;7(3):e542. doi: 10.1038/bcj.2017.21. No abstract available.


Thin Film Helps Detect Gravitational Waves.

Jacoby M.

ACS Cent Sci. 2017 Feb 22;3(2):92-94. doi: 10.1021/acscentsci.7b00049. Epub 2017 Feb 7. No abstract available.


Virescent tongue.

Ali AM, Jacoby M, Romee R.

Ann Hematol. 2017 May;96(5):883-884. doi: 10.1007/s00277-017-2961-6. Epub 2017 Feb 27. No abstract available.


Percutaneous coronary intervention using a combination of robotics and telecommunications by an operator in a separate physical location from the patient: an early exploration into the feasibility of telestenting (the REMOTE-PCI study).

Madder RD, VanOosterhout SM, Jacoby ME, Collins JS, Borgman AS, Mulder AN, Elmore MA, Campbell JL, McNamara RF, Wohns DH.

EuroIntervention. 2017 Jan 20;12(13):1569-1576. doi: 10.4244/EIJ-D-16-00363.


Mutational landscape and response are conserved in peripheral blood of AML and MDS patients during decitabine therapy.

Duncavage EJ, Uy GL, Petti AA, Miller CA, Lee YS, Tandon B, Gao F, Fronick CC, O'Laughlin M, Fulton RS, Wilson RK, Jacoby MA, Cashen AF, Wartman LD, Walter MJ, Westervelt P, Link DC, DiPersio JF, Ley TJ, Welch JS.

Blood. 2017 Mar 9;129(10):1397-1401. doi: 10.1182/blood-2016-10-745273. Epub 2017 Jan 12. No abstract available.


TP53 and Decitabine in Acute Myeloid Leukemia and Myelodysplastic Syndromes.

Welch JS, Petti AA, Miller CA, Fronick CC, O'Laughlin M, Fulton RS, Wilson RK, Baty JD, Duncavage EJ, Tandon B, Lee YS, Wartman LD, Uy GL, Ghobadi A, Tomasson MH, Pusic I, Romee R, Fehniger TA, Stockerl-Goldstein KE, Vij R, Oh ST, Abboud CN, Cashen AF, Schroeder MA, Jacoby MA, Heath SE, Luber K, Janke MR, Hantel A, Khan N, Sukhanova MJ, Knoebel RW, Stock W, Graubert TA, Walter MJ, Westervelt P, Link DC, DiPersio JF, Ley TJ.

N Engl J Med. 2016 Nov 24;375(21):2023-2036. doi: 10.1056/NEJMoa1605949.


Dynamic changes in the clonal structure of MDS and AML in response to epigenetic therapy.

Uy GL, Duncavage EJ, Chang GS, Jacoby MA, Miller CA, Shao J, Heath S, Elliott K, Reineck T, Fulton RS, Fronick CC, O'Laughlin M, Ganel L, Abboud CN, Cashen AF, DiPersio JF, Wilson RK, Link DC, Welch JS, Ley TJ, Graubert TA, Westervelt P, Walter MJ.

Leukemia. 2017 Apr;31(4):872-881. doi: 10.1038/leu.2016.282. Epub 2016 Oct 14.


Targeted sequencing informs the evaluation of normal karyotype cytopenic patients for low-grade myelodysplastic syndrome.

Duncavage EJ, O'Brien J, Vij K, Miller CA, Chang GS, Shao J, Jacoby MA, Heath S, Janke MR, Elliott K, Fulton RS, Fronick C, O'Laughlin M, Westervelt P, Ley TJ, Wilson RK, Walter MJ.

Leukemia. 2016 Dec;30(12):2422-2426. doi: 10.1038/leu.2016.247. Epub 2016 Aug 30. No abstract available.


Phase I study of azacitidine following donor lymphocyte infusion for relapsed acute myeloid leukemia post allogeneic stem cell transplantation.

Ghobadi A, Choi J, Fiala MA, Fletcher T, Liu J, Eissenberg LG, Abboud C, Cashen A, Vij R, Schroeder MA, Pusic I, Stockerl-Goldstein K, Jacoby M, Uy G, DiPersio J, Westervelt P.

Leuk Res. 2016 Oct;49:1-6. doi: 10.1016/j.leukres.2016.07.010. Epub 2016 Jul 22.


Screening for retinopathy of prematurity in a provincial hospital in Port Elizabeth, South Africa.

Jacoby MR, Du Toit L.

S Afr Med J. 2016 May 12;106(6). doi: 10.7196/SAMJ.2016.v106i6.10663.


A study of high-dose lenalidomide induction and low-dose lenalidomide maintenance therapy for patients with hypomethylating agent refractory myelodysplastic syndrome.

Cherian MA, Tibes R, Gao F, Fletcher T, Fiala M, Uy GL, Westervelt P, Jacoby MA, Cashen AF, Stockerl-Goldstein K, DiPersio JF, Vij R.

Leuk Lymphoma. 2016 Nov;57(11):2535-40. doi: 10.3109/10428194.2016.1173213. Epub 2016 Apr 27.


Large lipid-rich coronary plaques detected by near-infrared spectroscopy at non-stented sites in the target artery identify patients likely to experience future major adverse cardiovascular events.

Madder RD, Husaini M, Davis AT, VanOosterhout S, Khan M, Wohns D, McNamara RF, Wolschleger K, Gribar J, Collins JS, Jacoby M, Decker JM, Hendricks M, Sum ST, Madden S, Ware JH, Muller JE.

Eur Heart J Cardiovasc Imaging. 2016 Apr;17(4):393-9. doi: 10.1093/ehjci/jev340. Epub 2016 Jan 22.


Combined Near-Infrared Spectroscopy and Intravascular Ultrasound Imaging of Pre-Existing Coronary Artery Stents: Can Near-Infrared Spectroscopy Reliably Detect Neoatherosclerosis?

Madder RD, Khan M, Husaini M, Chi M, Dionne S, VanOosterhout S, Borgman A, Collins JS, Jacoby M.

Circ Cardiovasc Imaging. 2016 Jan;9(1). pii: e003576. doi: 10.1161/CIRCIMAGING.115.003576.


A phase I study of carfilzomib for relapsed or refractory acute myeloid and acute lymphoblastic leukemia.

Wartman LD, Fiala MA, Fletcher T, Hawkins ER, Cashen A, DiPersio JF, Jacoby MA, Stockerl-Goldstein KE, Pusic I, Uy GL, Westervelt P, Vij R.

Leuk Lymphoma. 2016;57(3):728-30. doi: 10.3109/10428194.2015.1076930. Epub 2015 Oct 5. No abstract available.


Implications of Tumor Clonal Heterogeneity in the Era of Next-Generation Sequencing.

Jacoby MA, Duncavage EJ, Walter MJ.

Trends Cancer. 2015 Dec;1(4):231-241. doi: 10.1016/j.trecan.2015.10.006. Epub 2015 Nov 25. Review.


Hand-foot syndrome following decitabine.

Ali AM, Jacoby M, Welch JS.

Ann Hematol. 2016 Feb;95(3):535-6. doi: 10.1007/s00277-015-2546-1. Epub 2015 Nov 6. No abstract available.


Maintenance Therapy with Decitabine after Allogeneic Stem Cell Transplantation for Acute Myelogenous Leukemia and Myelodysplastic Syndrome.

Pusic I, Choi J, Fiala MA, Gao F, Holt M, Cashen AF, Vij R, Abboud CN, Stockerl-Goldstein KE, Jacoby MA, Uy GL, Westervelt P, DiPersio JF.

Biol Blood Marrow Transplant. 2015 Oct;21(10):1761-9. doi: 10.1016/j.bbmt.2015.05.026. Epub 2015 Jun 5.


The ciliogenic transcription factor Rfx3 is required for the formation of the thalamocortical tract by regulating the patterning of prethalamus and ventral telencephalon.

Magnani D, Morlé L, Hasenpusch-Theil K, Paschaki M, Jacoby M, Schurmans S, Durand B, Theil T.

Hum Mol Genet. 2015 May 1;24(9):2578-93. doi: 10.1093/hmg/ddv021. Epub 2015 Jan 28.


[Cutis verticis gyrata as an early rare presenting sign of acromegaly].

Nissimov S, Jacoby M, Shteinshnaider M, Tzur I, Gorelik O.

Harefuah. 2014 May;153(5):253-4, 306. Hebrew.


A phase I dose escalation study of oral bexarotene in combination with intravenous decitabine in patients with AML.

Welch JS, Niu H, Uy GL, Westervelt P, Abboud CN, Vij R, Stockerl-Goldstein KE, Jacoby M, Pusic I, Schroeder MA, Dipersio JF, Cashen AF.

Am J Hematol. 2014 Aug;89(8):E103-8. doi: 10.1002/ajh.23735. Epub 2014 Apr 28.


Phase I study of oral clofarabine consolidation in adults aged 60 and older with acute myeloid leukemia.

Jacoby MA, Martin MG, Uy GL, Westervelt P, Dipersio JF, Cashen A, Stockerl-Goldstein K, Vij R, Luo J, Reineck T, Bernabe N, Abboud CN.

Am J Hematol. 2014 May;89(5):487-92. doi: 10.1002/ajh.23663. Epub 2014 Mar 3.


The DNA double-strand break response is abnormal in myeloblasts from patients with therapy-related acute myeloid leukemia.

Jacoby MA, De Jesus Pizarro RE, Shao J, Koboldt DC, Fulton RS, Zhou G, Wilson RK, Walter MJ.

Leukemia. 2014 Jun;28(6):1242-51. doi: 10.1038/leu.2013.368. Epub 2013 Dec 5.


Protective effect of cytomegalovirus reactivation on relapse after allogeneic hematopoietic cell transplantation in acute myeloid leukemia patients is influenced by conditioning regimen.

Manjappa S, Bhamidipati PK, Stokerl-Goldstein KE, DiPersio JF, Uy GL, Westervelt P, Liu J, Schroeder MA, Vij R, Abboud CN, Fehniger TA, Cashen AF, Pusic I, Jacoby M, Meera SJ, Romee R.

Biol Blood Marrow Transplant. 2014 Jan;20(1):46-52. doi: 10.1016/j.bbmt.2013.10.003. Epub 2013 Oct 10.


Acquired copy number alterations of miRNA genes in acute myeloid leukemia are uncommon.

Ramsingh G, Jacoby MA, Shao J, De Jesus Pizzaro RE, Shen D, Trissal M, Getz AH, Ley TJ, Walter MJ, Link DC.

Blood. 2013 Oct 10;122(15):e44-51. doi: 10.1182/blood-2013-03-488007. Epub 2013 Sep 5.


Patient considerations in the use of tapentadol for moderate to severe pain.

Vadivelu N, Huang Y, Mirante B, Jacoby M, Braveman FR, Hines RL, Sinatra R.

Drug Healthc Patient Saf. 2013 Jul 3;5:151-9. doi: 10.2147/DHPS.S28829. Print 2013.


Intravenous immunoglobulin for treatment of mild-to-moderate Alzheimer's disease: a phase 2, randomised, double-blind, placebo-controlled, dose-finding trial.

Dodel R, Rominger A, Bartenstein P, Barkhof F, Blennow K, Förster S, Winter Y, Bach JP, Popp J, Alferink J, Wiltfang J, Buerger K, Otto M, Antuono P, Jacoby M, Richter R, Stevens J, Melamed I, Goldstein J, Haag S, Wietek S, Farlow M, Jessen F.

Lancet Neurol. 2013 Mar;12(3):233-43. doi: 10.1016/S1474-4422(13)70014-0. Epub 2013 Jan 31.


Effectiveness of executive functions training within a virtual supermarket for adults with traumatic brain injury: a pilot study.

Jacoby M, Averbuch S, Sacher Y, Katz N, Weiss PL, Kizony R.

IEEE Trans Neural Syst Rehabil Eng. 2013 Mar;21(2):182-90. doi: 10.1109/TNSRE.2012.2235184. Epub 2012 Dec 31.


Interindividual variability and co-regulation of DNA methylation differ among blood cell populations.

Jacoby M, Gohrbandt S, Clausse V, Brons NH, Muller CP.

Epigenetics. 2012 Dec 1;7(12):1421-34. doi: 10.4161/epi.22845. Epub 2012 Nov 14.


Developmental defects and rescue from glucose intolerance of a catalytically-inactive novel Ship2 mutant mouse.

Dubois E, Jacoby M, Blockmans M, Pernot E, Schiffmann SN, Foukas LC, Henquin JC, Vanhaesebroeck B, Erneux C, Schurmans S.

Cell Signal. 2012 Nov;24(11):1971-80. doi: 10.1016/j.cellsig.2012.06.012. Epub 2012 Jun 30.


Detection of copy number alterations in acute myeloid leukemia and myelodysplastic syndromes.

Jacoby MA, Walter MJ.

Expert Rev Mol Diagn. 2012 Apr;12(3):253-64. doi: 10.1586/erm.12.18. Review.


The inositol Inpp5k 5-phosphatase affects osmoregulation through the vasopressin-aquaporin 2 pathway in the collecting system.

Pernot E, Terryn S, Cheong SC, Markadieu N, Janas S, Blockmans M, Jacoby M, Pouillon V, Gayral S, Rossier BC, Beauwens R, Erneux C, Devuyst O, Schurmans S.

Pflugers Arch. 2011 Dec;462(6):871-83. doi: 10.1007/s00424-011-1028-0. Epub 2011 Sep 22.


Managing medical bills on the brink of bankruptcy.

Jacoby MB, Holman M.

Yale J Health Policy Law Ethics. 2010 Spring;10(2):239-89, 291-7. No abstract available.


EB66 cell line, a duck embryonic stem cell-derived substrate for the industrial production of therapeutic monoclonal antibodies with enhanced ADCC activity.

Olivier S, Jacoby M, Brillon C, Bouletreau S, Mollet T, Nerriere O, Angel A, Danet S, Souttou B, Guehenneux F, Gauthier L, Berthomé M, Vié H, Beltraminelli N, Mehtali M.

MAbs. 2010 Jul-Aug;2(4):405-15. Epub 2010 Jul 1.


The importance of the pharmacist in reporting adverse drug reactions in the emergency department.

Ratz Y, Shafir I, Berkovitch S, Sharristh M, Jacoby M, Kozer E, Golik A, Berkovitch M, Bar-Haim S.

J Clin Pharmacol. 2010 Oct;50(10):1217-21. doi: 10.1177/0091270010361258. Epub 2010 Apr 23. No abstract available.


Identification of methionine sulfoxide diastereomers in immunoglobulin gamma antibodies using methionine sulfoxide reductase enzymes.

Khor HK, Jacoby ME, Squier TC, Chu GC, Chelius D.

MAbs. 2010 May-Jun;2(3):299-308. Epub 2010 May 11.

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