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Items: 1 to 50 of 344

1.

High in vitro susceptibility to the first-in-class spiropyrimidinetrione zoliflodacin among consecutive clinical Neisseria gonorrhoeae isolates from Thailand (2018) and South Africa (2015-2017).

Jacobsson S, Kularatne R, Kittiyaowamarn R, Maseko V, Paopang P, Sangprasert P, Sirivongrangson P, Piddock L, Wi T, Alirol E, Unemo M.

Antimicrob Agents Chemother. 2019 Sep 23. pii: AAC.01479-19. doi: 10.1128/AAC.01479-19. [Epub ahead of print]

PMID:
31548184
2.

Effects of cannabinoids on the development of chick embryos in ovo.

Gustafsson SB, Jacobsson SOP.

Sci Rep. 2019 Sep 17;9(1):13486. doi: 10.1038/s41598-019-50004-7.

3.

Anaerobic treatment of oil-contaminated wastewater with methane production using anaerobic moving bed biofilm reactors.

Morgan-Sagastume F, Jacobsson S, Olsson LE, Carlsson M, Gyllenhammar M, Sárvári Horváth I.

Water Res. 2019 Oct 15;163:114851. doi: 10.1016/j.watres.2019.07.018. Epub 2019 Jul 11.

PMID:
31323501
4.

Neisseria meningitidis-Induced Caspase-1 Activation in Human Innate Immune Cells Is LOS-Dependent.

Idosa BA, Kelly A, Jacobsson S, Demirel I, Fredlund H, Särndahl E, Persson A.

J Immunol Res. 2019 May 6;2019:6193186. doi: 10.1155/2019/6193186. eCollection 2019.

5.

In vitro activity of the ketolide cethromycin in multidrug-resistant clinical Neisseria gonorrhoeae isolates and international reference strains.

Jacobsson S, Alirol E, Unemo M.

J Chemother. 2019 Sep;31(5):246-251. doi: 10.1080/1120009X.2019.1615724. Epub 2019 May 20.

PMID:
31106713
6.

Increase of invasive meningococcal serogroup W disease in Europe, 2013 to 2017.

Krone M, Gray S, Abad R, Skoczyńska A, Stefanelli P, van der Ende A, Tzanakaki G, Mölling P, João Simões M, Křížová P, Emonet S, Caugant DA, Toropainen M, Vazquez J, Waśko I, Knol MJ, Jacobsson S, Rodrigues Bettencourt C, Musilek M, Born R, Vogel U, Borrow R.

Euro Surveill. 2019 Apr;24(14). doi: 10.2807/1560-7917.ES.2019.24.14.1800245.

7.

Ten years of external quality assessment (EQA) of Neisseria gonorrhoeae antimicrobial susceptibility testing in Europe elucidate high reliability of data.

Cole MJ, Quaye N, Jacobsson S, Day M, Fagan E, Ison C, Pitt R, Seaton S, Woodford N, Stary A, Pleininger S, Crucitti T, Hunjak B, Maikanti P, Hoffmann S, Viktorova J, Buder S, Kohl P, Tzelepi E, Siatravani E, Balla E, Hauksdóttir GS, Rose L, Stefanelli P, Carannante A, Pakarna G, Mifsud F, Cassar RZ, Linde I, Bergheim T, Steinbakk M, Mlynarczyk-Bonikowska B, Borrego MJ, Shepherd J, Pavlik P, Jeverica S, Vazquez J, Abad R, Weiss S, Spiteri G, Unemo M.

BMC Infect Dis. 2019 Mar 25;19(1):281. doi: 10.1186/s12879-019-3900-z.

8.

Antimicrobial susceptibility of Neisseria gonorrhoeae isolates and treatment of gonorrhoea patients in Ternopil and Dnipropetrovsk regions of Ukraine, 2013-2018.

Boiko I, Golparian D, Krynytska I, Bezkorovaina H, Frankenberg A, Onuchyna M, Jacobsson S, Unemo M.

APMIS. 2019 Jul;127(7):503-509. doi: 10.1111/apm.12948. Epub 2019 May 21.

PMID:
30903707
9.

In vitro activity of the novel oral antimicrobial SMT-571, with a new mechanism of action, against MDR and XDR Neisseria gonorrhoeae: future treatment option for gonorrhoea?

Jacobsson S, Mason C, Khan N, Meo P, Unemo M.

J Antimicrob Chemother. 2019 Jun 1;74(6):1591-1594. doi: 10.1093/jac/dkz060.

10.

Stably high azithromycin resistance and decreasing ceftriaxone susceptibility in Neisseria gonorrhoeae in 25 European countries, 2016.

Day MJ, Spiteri G, Jacobsson S, Woodford N, Amato-Gauci AJ, Cole MJ, Unemo M; Euro-GASP network.

BMC Infect Dis. 2018 Dec 3;18(1):609. doi: 10.1186/s12879-018-3528-4.

11.

WHO laboratory validation of Xpert® CT/NG and Xpert® TV on the GeneXpert system verifies high performances.

Jacobsson S, Boiko I, Golparian D, Blondeel K, Kiarie J, Toskin I, Peeling RW, Unemo M.

APMIS. 2018 Dec;126(12):907-912. doi: 10.1111/apm.12902.

12.

Performance characteristics of newer MIC gradient strip tests compared with the Etest for antimicrobial susceptibility testing of Neisseria gonorrhoeae.

Jönsson A, Jacobsson S, Foerster S, Cole MJ, Unemo M.

APMIS. 2018 Oct;126(10):822-827. doi: 10.1111/apm.12887. Epub 2018 Sep 6.

PMID:
30191618
13.

In vitro activity of the novel triazaacenaphthylene gepotidacin (GSK2140944) against MDR Neisseria gonorrhoeae.

Jacobsson S, Golparian D, Scangarella-Oman N, Unemo M.

J Antimicrob Chemother. 2018 Aug 1;73(8):2072-2077. doi: 10.1093/jac/dky162.

PMID:
29796611
14.

Public health surveillance of multidrug-resistant clones of Neisseria gonorrhoeae in Europe: a genomic survey.

Harris SR, Cole MJ, Spiteri G, Sánchez-Busó L, Golparian D, Jacobsson S, Goater R, Abudahab K, Yeats CA, Bercot B, Borrego MJ, Crowley B, Stefanelli P, Tripodo F, Abad R, Aanensen DM, Unemo M; Euro-GASP study group.

Lancet Infect Dis. 2018 Jul;18(7):758-768. doi: 10.1016/S1473-3099(18)30225-1. Epub 2018 May 15.

15.

Neisseria meningitidis carriage in Swedish teenagers associated with the serogroup W outbreak at the World Scout Jamboree, Japan 2015.

Jacobsson S, Stenmark B, Hedberg ST, Mölling P, Fredlund H.

APMIS. 2018 Apr;126(4):337-341. doi: 10.1111/apm.12819. Epub 2018 Mar 15.

PMID:
29543345
16.

Whole-Genome Sequencing of Emerging Invasive Neisseria meningitidis Serogroup W in Sweden.

Eriksson L, Hedberg ST, Jacobsson S, Fredlund H, Mölling P, Stenmark B.

J Clin Microbiol. 2018 Mar 26;56(4). pii: e01409-17. doi: 10.1128/JCM.01409-17. Print 2018 Apr.

17.

In vitro activity and time-kill curve analysis of sitafloxacin against a global panel of antimicrobial-resistant and multidrug-resistant Neisseria gonorrhoeae isolates.

Jönsson A, Foerster S, Golparian D, Hamasuna R, Jacobsson S, Lindberg M, Jensen JS, Ohnishi M, Unemo M.

APMIS. 2018 Jan;126(1):29-37. doi: 10.1111/apm.12777. Epub 2017 Nov 20.

PMID:
29154480
18.

Leptin independently predicts development of sepsis and its outcome.

Jacobsson S, Larsson P, Johansson G, Norberg M, Wadell G, Hallmans G, Winsö O, Söderberg S.

J Inflamm (Lond). 2017 Sep 11;14:19. doi: 10.1186/s12950-017-0167-2. eCollection 2017.

19.

In Vitro Activity of the Novel Pleuromutilin Lefamulin (BC-3781) and Effect of Efflux Pump Inactivation on Multidrug-Resistant and Extensively Drug-Resistant Neisseria gonorrhoeae.

Jacobsson S, Paukner S, Golparian D, Jensen JS, Unemo M.

Antimicrob Agents Chemother. 2017 Oct 24;61(11). pii: e01497-17. doi: 10.1128/AAC.01497-17. Print 2017 Nov.

20.

Overall Low Extended-Spectrum Cephalosporin Resistance but high Azithromycin Resistance in Neisseria gonorrhoeae in 24 European Countries, 2015.

Cole MJ, Spiteri G, Jacobsson S, Woodford N, Tripodo F, Amato-Gauci AJ, Unemo M; Euro-GASP network.

BMC Infect Dis. 2017 Sep 11;17(1):617. doi: 10.1186/s12879-017-2707-z.

21.

Comparison of neurons derived from mouse P19, rat PC12 and human SH-SY5Y cells in the assessment of chemical- and toxin-induced neurotoxicity.

Popova D, Karlsson J, Jacobsson SOP.

BMC Pharmacol Toxicol. 2017 Jun 5;18(1):42. doi: 10.1186/s40360-017-0151-8.

22.

Clinical presentation of invasive disease caused by Neisseria meningitidis serogroup Y in Sweden, 1995 to 2012.

Säll O, Stenmark B, Glimåker M, Jacobsson S, Mölling P, Olcén P, Fredlund H.

Epidemiol Infect. 2017 Jul;145(10):2137-2143. doi: 10.1017/S0950268817000929. Epub 2017 May 8.

23.

Increased Level of Serum Hepcidin in Female Adolescent Athletes.

Sandström G, Rödjer S, Jacobsson S, Nelson D, Börjesson M.

Clin J Sport Med. 2018 Mar;28(2):180-183. doi: 10.1097/JSM.0000000000000423.

PMID:
28452831
24.

An international invasive meningococcal disease outbreak due to a novel and rapidly expanding serogroup W strain, Scotland and Sweden, July to August 2015.

Lucidarme J, Scott KJ, Ure R, Smith A, Lindsay D, Stenmark B, Jacobsson S, Fredlund H, Cameron JC, Smith-Palmer A, McMenamin J, Gray SJ, Campbell H, Ladhani S, Findlow J, Mölling P, Borrow R.

Euro Surveill. 2016 Nov 10;21(45). pii: 30395. doi: 10.2807/1560-7917.ES.2016.21.45.30395.

25.

Non-Serotonergic Neurotoxicity by MDMA (Ecstasy) in Neurons Derived from Mouse P19 Embryonal Carcinoma Cells.

Popova D, Forsblad A, Hashemian S, Jacobsson SO.

PLoS One. 2016 Nov 18;11(11):e0166750. doi: 10.1371/journal.pone.0166750. eCollection 2016.

26.

Despite successful vaccines Neisseria meningitidis strikes again.

Jacobsson S.

Lancet Infect Dis. 2016 Nov;16(11):1212-1213. doi: 10.1016/S1473-3099(16)30273-0. Epub 2016 Aug 23. No abstract available.

PMID:
27567106
27.

Early hematopoiesis in multiple sclerosis patients.

Jons D, Kneider M, Fogelstrand L, Jeppsson A, Jacobsson S, Andersen O.

J Neuroimmunol. 2016 Oct 15;299:158-163. doi: 10.1016/j.jneuroim.2016.09.004. Epub 2016 Sep 13.

PMID:
27725115
28.

Antimicrobial resistance and Neisseria gonorrhoeae multiantigen sequence typing (NG-MAST) genotypes in N. gonorrhoeae during 2012-2014 in Karachi, Pakistan.

Jabeen K, Bhawan Mal P, Khan E, Chandio S, Jacobsson S, Unemo M.

BMC Infect Dis. 2016 Jul 22;16:353. doi: 10.1186/s12879-016-1673-1.

29.

The novel 2016 WHO Neisseria gonorrhoeae reference strains for global quality assurance of laboratory investigations: phenotypic, genetic and reference genome characterization.

Unemo M, Golparian D, Sánchez-Busó L, Grad Y, Jacobsson S, Ohnishi M, Lahra MM, Limnios A, Sikora AE, Wi T, Harris SR.

J Antimicrob Chemother. 2016 Nov;71(11):3096-3108. Epub 2016 Jul 17.

30.

WGS analysis and molecular resistance mechanisms of azithromycin-resistant (MIC >2 mg/L) Neisseria gonorrhoeae isolates in Europe from 2009 to 2014.

Jacobsson S, Golparian D, Cole M, Spiteri G, Martin I, Bergheim T, Borrego MJ, Crowley B, Crucitti T, Van Dam AP, Hoffmann S, Jeverica S, Kohl P, Mlynarczyk-Bonikowska B, Pakarna G, Stary A, Stefanelli P, Pavlik P, Tzelepi E, Abad R, Harris SR, Unemo M.

J Antimicrob Chemother. 2016 Nov;71(11):3109-3116. Epub 2016 Jul 17.

PMID:
27432597
31.

High Content Analysis of Human Pluripotent Stem Cell Derived Hepatocytes Reveals Drug Induced Steatosis and Phospholipidosis.

Pradip A, Steel D, Jacobsson S, Holmgren G, Ingelman-Sundberg M, Sartipy P, Björquist P, Johansson I, Edsbagge J.

Stem Cells Int. 2016;2016:2475631. doi: 10.1155/2016/2475631. Epub 2016 Jan 5.

32.

Genetic Resistance Determinants, In Vitro Time-Kill Curve Analysis and Pharmacodynamic Functions for the Novel Topoisomerase II Inhibitor ETX0914 (AZD0914) in Neisseria gonorrhoeae.

Foerster S, Golparian D, Jacobsson S, Hathaway LJ, Low N, Shafer WM, Althaus CL, Unemo M.

Front Microbiol. 2015 Dec 10;6:1377. doi: 10.3389/fmicb.2015.01377. eCollection 2015.

33.

Is the Emergence of the N. meningitidis Serogroup W ST-11 Hajj Outbreak Unraveling in the New Era of WGS?

Törös B, Jacobsson S.

EBioMedicine. 2015 Oct 9;2(10):1294-5. doi: 10.1016/j.ebiom.2015.10.011. eCollection 2015 Oct. No abstract available.

34.

One Standardized Differentiation Procedure Robustly Generates Homogenous Hepatocyte Cultures Displaying Metabolic Diversity from a Large Panel of Human Pluripotent Stem Cells.

Asplund A, Pradip A, van Giezen M, Aspegren A, Choukair H, Rehnström M, Jacobsson S, Ghosheh N, El Hajjam D, Holmgren S, Larsson S, Benecke J, Butron M, Wigander A, Noaksson K, Sartipy P, Björquist P, Edsbagge J, Küppers-Munther B.

Stem Cell Rev Rep. 2016 Feb;12(1):90-104. doi: 10.1007/s12015-015-9621-9.

PMID:
26385115
35.

Is the tide turning again for cephalosporin resistance in Neisseria gonorrhoeae in Europe? Results from the 2013 European surveillance.

Cole MJ, Spiteri G, Jacobsson S, Pitt R, Grigorjev V, Unemo M; Euro-GASP Network.

BMC Infect Dis. 2015 Aug 11;15:321. doi: 10.1186/s12879-015-1013-x.

36.

High in vitro susceptibility to the novel spiropyrimidinetrione ETX0914 (AZD0914) among 873 contemporary clinical Neisseria gonorrhoeae isolates from 21 European countries from 2012 to 2014.

Unemo M, Ringlander J, Wiggins C, Fredlund H, Jacobsson S, Cole M.

Antimicrob Agents Chemother. 2015 Sep;59(9):5220-5. doi: 10.1128/AAC.00786-15. Epub 2015 Jun 15.

37.

Meningococcal serogroup Y disease in Europe: Continuation of high importance in some European regions in 2013.

Bröker M, Emonet S, Fazio C, Jacobsson S, Koliou M, Kuusi M, Pace D, Paragi M, Pysik A, Simões MJ, Skoczynska A, Stefanelli P, Toropainen M, Taha MK, Tzanakaki G.

Hum Vaccin Immunother. 2015;11(9):2281-6. doi: 10.1080/21645515.2015.1051276.

38.

Genome-Based Characterization of Emergent Invasive Neisseria meningitidis Serogroup Y Isolates in Sweden from 1995 to 2012.

Törös B, Hedberg ST, Unemo M, Jacobsson S, Hill DM, Olcén P, Fredlund H, Bratcher HB, Jolley KA, Maiden MC, Mölling P.

J Clin Microbiol. 2015 Jul;53(7):2154-62. doi: 10.1128/JCM.03524-14. Epub 2015 Apr 29.

39.

Surveillance of invasive Neisseria meningitidis with a serogroup Y update, Sweden 2010 to 2012.

Törös B, Thulin Hedberg S, Jacobsson S, Fredlund H, Olcén P, Mölling P.

Euro Surveill. 2014 Oct 23;19(42). pii: 20940.

40.

In vitro activities of the novel bicyclolides modithromycin (EDP-420, EP-013420, S-013420) and EDP-322 against MDR clinical Neisseria gonorrhoeae isolates and international reference strains.

Jacobsson S, Golparian D, Phan LT, Ohnishi M, Fredlund H, Or YS, Unemo M.

J Antimicrob Chemother. 2015 Jan;70(1):173-7. doi: 10.1093/jac/dku344. Epub 2014 Sep 1.

PMID:
25182063
41.

High in vitro activity of the novel spiropyrimidinetrione AZD0914, a DNA gyrase inhibitor, against multidrug-resistant Neisseria gonorrhoeae isolates suggests a new effective option for oral treatment of gonorrhea.

Jacobsson S, Golparian D, Alm RA, Huband M, Mueller J, Jensen JS, Ohnishi M, Unemo M.

Antimicrob Agents Chemother. 2014 Sep;58(9):5585-8. doi: 10.1128/AAC.03090-14. Epub 2014 Jun 30.

42.

Serum estradiol associates with blood hemoglobin in elderly men: the MrOS Sweden study.

Lewerin C, Nilsson-Ehle H, Jacobsson S, Johansson H, Sundh V, Karlsson MK, Lorentzon M, Barrett-Connor E, Vandenput L, Ohlsson C, Mellström D.

J Clin Endocrinol Metab. 2014 Jul;99(7):2549-56. doi: 10.1210/jc.2013-4111. Epub 2014 Apr 14.

PMID:
24731011
43.

Implications of differential age distribution of disease-associated meningococcal lineages for vaccine development.

Brehony C, Trotter CL, Ramsay ME, Chandra M, Jolley KA, van der Ende A, Carion F, Berthelsen L, Hoffmann S, Harðardóttir H, Vazquez JA, Murphy K, Toropainen M, Caniça M, Ferreira E, Diggle M, Edwards GF, Taha MK, Stefanelli P, Kriz P, Gray SJ, Fox AJ, Jacobsson S, Claus H, Vogel U, Tzanakaki G, Heuberger S, Caugant DA, Frosch M, Maiden MC.

Clin Vaccine Immunol. 2014 Jun;21(6):847-53. doi: 10.1128/CVI.00133-14. Epub 2014 Apr 2.

44.

Decreased susceptibility to chlorhexidine and prevalence of disinfectant resistance genes among clinical isolates of Staphylococcus epidermidis.

Prag G, Falk-Brynhildsen K, Jacobsson S, Hellmark B, Unemo M, Söderquist B.

APMIS. 2014 Oct;122(10):961-7. doi: 10.1111/apm.12239. Epub 2014 Mar 15.

PMID:
24628476
45.

Meningococcal serogroup Y emergence in Europe: high importance in some European regions in 2012.

Bröker M, Bukovski S, Culic D, Jacobsson S, Koliou M, Kuusi M, Simões MJ, Skoczynska A, Toropainen M, Taha MK, Tzanakaki G.

Hum Vaccin Immunother. 2014;10(6):1725-8. doi: 10.4161/hv.28206. Epub 2014 Mar 7.

46.

Ketoconazole inhibits the cellular uptake of anandamide via inhibition of FAAH at pharmacologically relevant concentrations.

Björklund E, Larsson TN, Jacobsson SO, Fowler CJ.

PLoS One. 2014 Jan 23;9(1):e87542. doi: 10.1371/journal.pone.0087542. eCollection 2014.

47.

A fluorescence microplate screen assay for the detection of neurite outgrowth and neurotoxicity using an antibody against βIII-tubulin.

Popova D, Jacobsson SO.

Toxicol In Vitro. 2014 Apr;28(3):411-8. doi: 10.1016/j.tiv.2013.12.009. Epub 2013 Dec 31.

PMID:
24388784
48.

Low holotranscobalamin and cobalamins predict incident fractures in elderly men: the MrOS Sweden.

Lewerin C, Nilsson-Ehle H, Jacobsson S, Johansson H, Sundh V, Karlsson MK, Ljunggren Ö, Lorentzon M, Kanis JA, Lerner UH, Cummings SR, Ohlsson C, Mellström D.

Osteoporos Int. 2014 Jan;25(1):131-40. doi: 10.1007/s00198-013-2527-y. Epub 2013 Oct 16.

PMID:
24129588
49.

Holotranscobalamin is not influenced by decreased renal function in elderly men: the MrOS Sweden study.

Lewerin C, Nilsson-Ehle H, Jacobsson S, Karlsson MK, Ohlsson C, Mellström D.

Ann Clin Biochem. 2013 Nov;50(Pt 6):585-94. doi: 10.1177/0004563212474939. Epub 2013 Jul 30.

PMID:
23901143
50.

Drug metabolizing enzyme and transporter protein profiles of hepatocytes derived from human embryonic and induced pluripotent stem cells.

Ulvestad M, Nordell P, Asplund A, Rehnström M, Jacobsson S, Holmgren G, Davidson L, Brolén G, Edsbagge J, Björquist P, Küppers-Munther B, Andersson TB.

Biochem Pharmacol. 2013 Sep 1;86(5):691-702. doi: 10.1016/j.bcp.2013.06.029. Epub 2013 Jul 12.

PMID:
23856292

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