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Essential Role of HTLV-1 orf-I in Lethal Proliferation of CD4+ Cells in Humanized Mice.

Galli V, Nixon CC, Strbo N, Artesi M, de Castro-Amarante MF, McKinnon K, Fujikawa D, Omsland M, Washington-Parks R, Romero L, Caruso B, Durkin K, Brown S, Karim B, Vaccari M, Jacobson S, Zack JA, Van den Broeke A, Pise-Masison C, Franchini G.

J Virol. 2019 Jul 17. pii: JVI.00565-19. doi: 10.1128/JVI.00565-19. [Epub ahead of print]


The role of antimicrobial prophylaxis in patients with head and neck cancer undergoing chemoradiation.

Jaeger AT, Connelly JE, Jin R, Jacobson SN, Leidner RS.

J Oncol Pharm Pract. 2019 Jul 9:1078155219859614. doi: 10.1177/1078155219859614. [Epub ahead of print]


Discovery of a Potent and Selective CCR4 Antagonist That Inhibits Treg Trafficking into the Tumor Microenvironment.

Jackson JJ, Ketcham JM, Younai A, Abraham B, Biannic B, Beck HP, Bui MHT, Chian D, Cutler G, Diokno R, Hu DX, Jacobson S, Karbarz E, Kassner PD, Marshall L, McKinnell J, Meleza C, Okal A, Pookot D, Reilly MK, Robles O, Shunatona HP, Talay O, Walker JR, Wadsworth A, Wustrow DJ, Zibinsky M.

J Med Chem. 2019 Jul 11;62(13):6190-6213. doi: 10.1021/acs.jmedchem.9b00506. Epub 2019 Jul 1.


Faster cognitive decline in dementia due to Alzheimer disease with clinically undiagnosed Lewy body disease.

Malek-Ahmadi M, Beach TG, Zamrini E, Adler CH, Sabbagh MN, Shill HA, Jacobson SA, Belden CM, Caselli RJ, Woodruff BK, Rapscak SZ, Ahern GL, Shi J, Caviness JN, Driver-Dunckley E, Mehta SH, Shprecher DR, Spann BM, Tariot P, Davis KJ, Long KE, Nicholson LR, Intorcia A, Glass MJ, Walker JE, Callan M, Curry J, Cutler B, Oliver J, Arce R, Walker DG, Lue LF, Serrano GE, Sue LI, Chen K, Reiman EM.

PLoS One. 2019 Jun 25;14(6):e0217566. doi: 10.1371/journal.pone.0217566. eCollection 2019.


Treatment Potential for Macular Cone Vision in Leber Congenital Amaurosis Due to CEP290 or NPHP5 Mutations: Predictions From Artificial Intelligence.

Sumaroka A, Garafalo AV, Semenov EP, Sheplock R, Krishnan AK, Roman AJ, Jacobson SG, Cideciyan AV.

Invest Ophthalmol Vis Sci. 2019 Jun 3;60(7):2551-2562. doi: 10.1167/iovs.19-27156.


Pre-analytic Considerations for Mass Spectrometry-Based Untargeted Metabolomics Data.

Reinhold D, Pielke-Lombardo H, Jacobson S, Ghosh D, Kechris K.

Methods Mol Biol. 2019;1978:323-340. doi: 10.1007/978-1-4939-9236-2_20.


Short-Wavelength Sensitive Cone (S-cone) Testing as an Outcome Measure for NR2E3 Clinical Treatment Trials.

Roman AJ, Powers CA, Semenov EP, Sheplock R, Aksianiuk V, Russell RC, Sumaroka A, Garafalo AV, Cideciyan AV, Jacobson SG.

Int J Mol Sci. 2019 May 21;20(10). pii: E2497. doi: 10.3390/ijms20102497.


Neuroimmunology of Human T-Lymphotropic Virus Type 1-Associated Myelopathy/Tropical Spastic Paraparesis.

Nozuma S, Jacobson S.

Front Microbiol. 2019 Apr 24;10:885. doi: 10.3389/fmicb.2019.00885. eCollection 2019. Review.


sGC stimulator praliciguat suppresses stellate cell fibrotic transformation and inhibits fibrosis and inflammation in models of NASH.

Hall KC, Bernier SG, Jacobson S, Liu G, Zhang PY, Sarno R, Catanzano V, Currie MG, Masferrer JL.

Proc Natl Acad Sci U S A. 2019 May 28;116(22):11057-11062. doi: 10.1073/pnas.1821045116. Epub 2019 May 13.


HTLV-1 HBZ Protein Resides Exclusively in the Cytoplasm of Infected Cells in Asymptomatic Carriers and HAM/TSP Patients.

Forlani G, Baratella M, Tedeschi A, Pique C, Jacobson S, Accolla RS.

Front Microbiol. 2019 Apr 26;10:819. doi: 10.3389/fmicb.2019.00819. eCollection 2019.


Mutation spectrum and clinical investigation of achromatopsia patients with mutations in the GNAT2 gene.

Felden J, Baumann B, Ali M, Audo I, Ayuso C, Bocquet B, Casteels I, Garcia-Sandoval B, Jacobson SG, Jurklies B, Kellner U, Kessel L, Lorenz B, McKibbin M, Meunier I, de Ravel T, Rosenberg T, Rüther K, Vadala M, Wissinger B, Stingl K, Kohl S.

Hum Mutat. 2019 May 6. doi: 10.1002/humu.23768. [Epub ahead of print]


Extracellular Vesicles and Ebola Virus: A New Mechanism of Immune Evasion.

Pleet ML, DeMarino C, Stonier SW, Dye JM, Jacobson S, Aman MJ, Kashanchi F.

Viruses. 2019 May 2;11(5). pii: E410. doi: 10.3390/v11050410. Review.


Surgical Outcomes of Prepectoral Versus Subpectoral Implant-based Breast Reconstruction in Young Women.

Manrique OJ, Banuelos J, Abu-Ghname A, Nguyen MD, Tran NV, Martinez-Jorge J, Harless C, Sharaf B, Jakub JW, Degnim AC, Boughey JC, Jacobson SR.

Plast Reconstr Surg Glob Open. 2019 Mar 13;7(3):e2119. doi: 10.1097/GOX.0000000000002119. eCollection 2019 Mar.


Health-related quality of life as predictor of mortality in end-stage renal disease patients: an observational study.

Pei M, Aguiar R, Pagels AA, Heimbürger O, Stenvinkel P, Bárány P, Medin C, Jacobson SH, Hylander B, Lindholm B, Qureshi AR.

BMC Nephrol. 2019 Apr 29;20(1):144. doi: 10.1186/s12882-019-1318-x.


Leber Congenital Amaurosis (LCA): Potential for Improvement of Vision.

Cideciyan AV, Jacobson SG.

Invest Ophthalmol Vis Sci. 2019 Apr 1;60(5):1680-1695. doi: 10.1167/iovs.19-26672. No abstract available.


Pembrolizumab Treatment for Progressive Multifocal Leukoencephalopathy.

Cortese I, Muranski P, Enose-Akahata Y, Ha SK, Smith B, Monaco M, Ryschkewitsch C, Major EO, Ohayon J, Schindler MK, Beck E, Reoma LB, Jacobson S, Reich DS, Nath A.

N Engl J Med. 2019 Apr 25;380(17):1597-1605. doi: 10.1056/NEJMoa1815039. Epub 2019 Apr 10.


Real-world use of rescue inhaler sensors, electronic symptom questionnaires and physical activity monitors in COPD.

Bowler R, Allinder M, Jacobson S, Miller A, Miller B, Tal-Singer R, Locantore N.

BMJ Open Respir Res. 2019 Feb 18;6(1):e000350. doi: 10.1136/bmjresp-2018-000350. eCollection 2019.


Infection with HHV-6 and its role in epilepsy.

Bartolini L, Theodore WH, Jacobson S, Gaillard WD.

Epilepsy Res. 2019 Jul;153:34-39. doi: 10.1016/j.eplepsyres.2019.03.016. Epub 2019 Mar 29. Review.


The "central vein sign" in inflammatory demyelination: The role of fibrillar collagen type I.

Absinta M, Nair G, Monaco MCG, Maric D, Lee NJ, Ha SK, Luciano NJ, Sati P, Jacobson S, Reich DS.

Ann Neurol. 2019 Jun;85(6):934-942. doi: 10.1002/ana.25461. Epub 2019 Mar 30.


Two-stage prepectoral breast reconstruction.

Nahabedian MY, Jacobson SR.

Gland Surg. 2019 Feb;8(1):43-52. doi: 10.21037/gs.2018.09.04. Review.


Increased concentrations of platelet- and endothelial-derived microparticles in patients with myocardial infarction and reduced renal function- a descriptive study.

Mörtberg J, Lundwall K, Mobarrez F, Wallén H, Jacobson SH, Spaak J.

BMC Nephrol. 2019 Mar 1;20(1):71. doi: 10.1186/s12882-019-1261-x.


The Role of IGSF3 in Cell Adhesion, Proliferation, and Cell Migration.

Schweitzer K, Ni K, Jacobson S, Bronova I, Berdyshev E, Bowler R, Petrache I.

Ann Am Thorac Soc. 2018 Dec;15(Supplement_4):S291. doi: 10.1513/AnnalsATS.201808-586MG.


The spectrum of spinal cord lesions in a primate model of multiple sclerosis.

Lefeuvre JA, Guy JR, Luciano NJ, Ha SK, Leibovitch E, Santin MD, Silva AC, Jacobson S, Lehéricy S, Reich DS, Sati P.

Mult Scler. 2019 Feb 7:1352458518822408. doi: 10.1177/1352458518822408. [Epub ahead of print]


Comprehensive Analysis of TCR-β Repertoire in Patients with Neurological Immune-mediated Disorders.

Alves Sousa AP, Johnson KR, Ohayon J, Zhu J, Muraro PA, Jacobson S.

Sci Rep. 2019 Jan 23;9(1):344. doi: 10.1038/s41598-018-36274-7.


Hardly habitual: chimpanzees and gorillas show flexibility in their motor responses when presented with a causally-clear task.

Jacobson SL, Hopper LM.

PeerJ. 2019 Jan 8;7:e6195. doi: 10.7717/peerj.6195. eCollection 2019.


A G86R mutation in the calcium-sensor protein GCAP1 alters regulation of retinal guanylyl cyclase and causes dominant cone-rod degeneration.

Peshenko IV, Cideciyan AV, Sumaroka A, Olshevskaya EV, Scholten A, Abbas S, Koch KW, Jacobson SG, Dizhoor AM.

J Biol Chem. 2019 Mar 8;294(10):3476-3488. doi: 10.1074/jbc.RA118.006180. Epub 2019 Jan 8.


Achievement of renal anemia KDIGO targets by two different clinical strategies - a European hemodialysis multicenter analysis.

Drozdz M, Weigert A, Silva F, Frazão J, Alsuwaida A, Krishnan M, Kleophas W, Brzosko S, Johansson FK, Jacobson SH.

BMC Nephrol. 2019 Jan 7;20(1):5. doi: 10.1186/s12882-018-1196-7.


Evolution of Intermediates during Capsid Assembly of Hepatitis B Virus with Phenylpropenamide-Based Antivirals.

Kondylis P, Schlicksup CJ, Katen SP, Lee LS, Zlotnick A, Jacobson SC.

ACS Infect Dis. 2019 May 10;5(5):769-777. doi: 10.1021/acsinfecdis.8b00290. Epub 2019 Feb 4.


Gradual reduction in exercise capacity in chronic kidney disease is associated with systemic oxygen delivery factors.

Wallin H, Asp AM, Wallquist C, Jansson E, Caidahl K, Hylander Rössner B, Jacobson SH, Rickenlund A, Eriksson MJ.

PLoS One. 2018 Dec 19;13(12):e0209325. doi: 10.1371/journal.pone.0209325. eCollection 2018.


Effect of an intravitreal antisense oligonucleotide on vision in Leber congenital amaurosis due to a photoreceptor cilium defect.

Cideciyan AV, Jacobson SG, Drack AV, Ho AC, Charng J, Garafalo AV, Roman AJ, Sumaroka A, Han IC, Hochstedler MD, Pfeifer WL, Sohn EH, Taiel M, Schwartz MR, Biasutto P, Wit W, Cheetham ME, Adamson P, Rodman DM, Platenburg G, Tome MD, Balikova I, Nerinckx F, Zaeytijd J, Van Cauwenbergh C, Leroy BP, Russell SR.

Nat Med. 2019 Feb;25(2):225-228. doi: 10.1038/s41591-018-0295-0. Epub 2018 Dec 17.


Reply to Zahednasab et al.: HHV-6 and marmoset EAE.

Leibovitch EC, Jacobson S.

Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):E12127. doi: 10.1073/pnas.1818755115. Epub 2018 Dec 11. No abstract available.


Competition between Normative and Drug-Induced Virus Self-Assembly Observed with Single-Particle Methods.

Kondylis P, Schlicksup CJ, Brunk NE, Zhou J, Zlotnick A, Jacobson SC.

J Am Chem Soc. 2019 Jan 23;141(3):1251-1260. doi: 10.1021/jacs.8b10131. Epub 2018 Dec 31.


Blue Cone Monochromacy Caused by the C203R Missense Mutation or Large Deletion Mutations.

Sumaroka A, Garafalo AV, Cideciyan AV, Charng J, Roman AJ, Choi W, Saxena S, Aksianiuk V, Kohl S, Wissinger B, Jacobson SG.

Invest Ophthalmol Vis Sci. 2018 Dec 3;59(15):5762-5772. doi: 10.1167/iovs.18-25280.


Development and validation of a quantitative choline food frequency questionnaire for use with drinking and non-drinking pregnant women in Cape Town, South Africa.

Carter RC, Jacobson SW, Booley S, Najaar B, Dodge NC, Bechard LJ, Meintjes EM, Molteno CD, Duggan CP, Jacobson JL, Senekal M.

Nutr J. 2018 Nov 22;17(1):108. doi: 10.1186/s12937-018-0411-5.


Metabolomics and transcriptomics pathway approach reveals outcome-specific perturbations in COPD.

Cruickshank-Quinn CI, Jacobson S, Hughes G, Powell RL, Petrache I, Kechris K, Bowler R, Reisdorph N.

Sci Rep. 2018 Nov 20;8(1):17132. doi: 10.1038/s41598-018-35372-w.


Analytical Techniques to Characterize the Structure, Properties, and Assembly of Virus Capsids.

Kondylis P, Schlicksup CJ, Zlotnick A, Jacobson SC.

Anal Chem. 2019 Jan 2;91(1):622-636. doi: 10.1021/acs.analchem.8b04824. Epub 2018 Dec 3. No abstract available.


Factors of Engagement and Patient-Reported Outcomes in a Stage IV Breast Cancer Facebook Group.

Kashian N, Jacobson S.

Health Commun. 2018 Oct 23:1-8. doi: 10.1080/10410236.2018.1536962. [Epub ahead of print]


Prenatal alcohol exposure affects brain function during place learning in a virtual environment differently in boys and girls.

Woods KJ, Thomas KGF, Molteno CD, Jacobson JL, Jacobson SW, Meintjes EM.

Brain Behav. 2018 Nov;8(11):e01103. doi: 10.1002/brb3.1103. Epub 2018 Oct 23.


Detection of HHV-6 and EBV and Cytokine Levels in Saliva From Children With Seizures: Results of a Multi-Center Cross-Sectional Study.

Bartolini L, Piras E, Sullivan K, Gillen S, Bumbut A, Lin CM, Leibovitch EC, Graves JS, Waubant EL, Chamberlain JM, Gaillard WD, Jacobson S.

Front Neurol. 2018 Oct 5;9:834. doi: 10.3389/fneur.2018.00834. eCollection 2018.


Herpesvirus trigger accelerates neuroinflammation in a nonhuman primate model of multiple sclerosis.

Leibovitch EC, Caruso B, Ha SK, Schindler MK, Lee NJ, Luciano NJ, Billioux BJ, Guy JR, Yen C, Sati P, Silva AC, Reich DS, Jacobson S.

Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):11292-11297. doi: 10.1073/pnas.1811974115. Epub 2018 Oct 15.


Variegated yet non-random rod and cone photoreceptor disease patterns in RPGR-ORF15-associated retinal degeneration.

Charng J, Cideciyan AV, Jacobson SG, Sumaroka A, Schwartz SB, Swider M, Roman AJ, Sheplock R, Anand M, Peden MC, Khanna H, Heon E, Wright AF, Swaroop A.

Hum Mol Genet. 2019 Jan 1;28(1):175. doi: 10.1093/hmg/ddy342. No abstract available.


Treating endothelial dysfunction with vitamin D in chronic kidney disease: a meta-analysis.

Lundwall K, Jacobson SH, Jörneskog G, Spaak J.

BMC Nephrol. 2018 Sep 25;19(1):247. doi: 10.1186/s12882-018-1042-y.


Lewy body pathology in Alzheimer's disease: A clinicopathological prospective study.

Savica R, Beach TG, Hentz JG, Sabbagh MN, Serrano GE, Sue LI, Dugger BN, Shill HA, Driver-Dunckley E, Caviness JN, Mehta SH, Jacobson SA, Belden CM, Davis KJ, Zamrini E, Shprecher DR, Adler CH.

Acta Neurol Scand. 2019 Jan;139(1):76-81. doi: 10.1111/ane.13028. Epub 2018 Oct 7.


Translational Retinal Research and Therapies.

Hardcastle AJ, Sieving PA, Sahel JA, Jacobson SG, Cideciyan AV, Flannery JG, Beltran WA, Aguirre GD.

Transl Vis Sci Technol. 2018 Sep 13;7(5):8. doi: 10.1167/tvst.7.5.8. eCollection 2018 Sep.


Assisting the School in Responding to a Suicide Death: What Every Psychiatrist Should Know.

Aron EJ, Bostic JQ, Grumet JG, Jacobson S.

Child Adolesc Psychiatr Clin N Am. 2018 Oct;27(4):607-619. doi: 10.1016/j.chc.2018.05.007. Epub 2018 Jul 18.


Progression in X-linked Retinitis Pigmentosa Due to ORF15-RPGR Mutations: Assessment of Localized Vision Changes Over 2 Years.

Cideciyan AV, Charng J, Roman AJ, Sheplock R, Garafalo AV, Heon E, Jacobson SG.

Invest Ophthalmol Vis Sci. 2018 Sep 4;59(11):4558-4566. doi: 10.1167/iovs.18-24931.



Carr LL, Jacobson S, Bowler RP.

Chest. 2018 Sep;154(3):721. doi: 10.1016/j.chest.2018.05.024. No abstract available.


Viral antigens detectable in CSF exosomes from patients with retrovirus associated neurologic disease: functional role of exosomes.

Anderson MR, Pleet ML, Enose-Akahata Y, Erickson J, Monaco MC, Akpamagbo Y, Velluci A, Tanaka Y, Azodi S, Lepene B, Jones J, Kashanchi F, Jacobson S.

Clin Transl Med. 2018 Aug 27;7(1):24. doi: 10.1186/s40169-018-0204-7.


Missed Hemodialysis Treatments: International Variation, Predictors, and Outcomes in the Dialysis Outcomes and Practice Patterns Study (DOPPS).

Al Salmi I, Larkina M, Wang M, Subramanian L, Morgenstern H, Jacobson SH, Hakim R, Tentori F, Saran R, Akiba T, Tomilina NA, Port FK, Robinson BM, Pisoni RL.

Am J Kidney Dis. 2018 Nov;72(5):634-643. doi: 10.1053/j.ajkd.2018.04.019. Epub 2018 Aug 23.


Mutation-independent rhodopsin gene therapy by knockdown and replacement with a single AAV vector.

Cideciyan AV, Sudharsan R, Dufour VL, Massengill MT, Iwabe S, Swider M, Lisi B, Sumaroka A, Marinho LF, Appelbaum T, Rossmiller B, Hauswirth WW, Jacobson SG, Lewin AS, Aguirre GD, Beltran WA.

Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8547-E8556. doi: 10.1073/pnas.1805055115. Epub 2018 Aug 20.

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