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Identification of genetic variants associated with tacrolimus metabolism in kidney transplant recipients by extreme phenotype sampling and next generation sequencing.

Dorr CR, Wu B, Remmel RP, Muthusamy A, Schladt DP, Abrahante JE, Guan W, Mannon RB, Matas AJ, Oetting WS, Jacobson PA, Israni AK; for DeKAF Genomics.

Pharmacogenomics J. 2018 Nov 16. doi: 10.1038/s41397-018-0063-z. [Epub ahead of print]


Urinary microbiome associated with chronic allograft dysfunction in kidney transplant recipients.

Wu JF, Muthusamy A, Al-Ghalith GA, Knights D, Guo B, Wu B, Remmel RP, Schladt DP, Alegre ML, Oetting WS, Jacobson PA, Israni AK.

Clin Transplant. 2018 Oct 29:e13436. doi: 10.1111/ctr.13436. [Epub ahead of print]


Tacrolimus trough and dose intra-patient variability and CYP3A5 genotype: Effects on acute rejection and graft failure in European American and African American kidney transplant recipients.

Seibert SR, Schladt DP, Wu B, Guan W, Dorr C, Remmel RP, Matas AJ, Mannon RB, Israni AK, Oetting WS, Jacobson PA.

Clin Transplant. 2018 Oct 14:e13424. doi: 10.1111/ctr.13424. [Epub ahead of print]


Changes in English Past Tense Use by Bilingual School-Age Children With and Without Developmental Language Disorder.

Jacobson PF, Yu YH.

J Speech Lang Hear Res. 2018 Oct 26;61(10):2532-2546. doi: 10.1044/2018_JSLHR-L-17-0044.


Priorities for Investing in Community Health Improvement: A Comparison of Decision Makers in Public Health, Nonprofit Hospitals, and Community Nonprofits.

Rozier MD, Singh SR, Jacobson PD, Prosser LA.

J Public Health Manag Pract. 2018 Sep 26. doi: 10.1097/PHH.0000000000000848. [Epub ahead of print]


Tacrolimus Elimination in Four Patients With a CYP3A5*3/*3 CYP3A4*22/*22 Genotype Combination.

Scheibner A, Remmel R, Schladt D, Oetting WS, Guan W, Wu B, Dorr C, Israni A, Jacobson PA.

Pharmacotherapy. 2018 May 26. doi: 10.1002/phar.2131. [Epub ahead of print]


Long-term incidence of serious fall-related injuries after bariatric surgery in Swedish obese subjects.

Carlsson LMS, Sjöholm K, Ahlin S, Jacobson P, Andersson-Assarsson JC, Karlsson Lindahl L, Maglio C, Karlsson C, Hjorth S, Taube M, Carlsson B, Svensson PA, Peltonen M.

Int J Obes (Lond). 2018 May 24. doi: 10.1038/s41366-018-0097-y. [Epub ahead of print]


The influence of disease severity and lifestyle factors on the peak annual 25(OH)D value of COPD patients.

Kentson M, Leanderson P, Jacobson P, Persson HL.

Int J Chron Obstruct Pulmon Dis. 2018 Apr 27;13:1389-1398. doi: 10.2147/COPD.S156121. eCollection 2018.


Oxidant status, iron homeostasis, and carotenoid levels of COPD patients with advanced disease and LTOT.

Kentson M, Leanderson P, Jacobson P, Persson HL.

Eur Clin Respir J. 2018 Mar 9;5(1):1447221. doi: 10.1080/20018525.2018.1447221. eCollection 2018.


NPHP1 (Nephrocystin-1) Gene Deletions Cause Adult-Onset ESRD.

Snoek R, van Setten J, Keating BJ, Israni AK, Jacobson PA, Oetting WS, Matas AJ, Mannon RB, Zhang Z, Zhang W, Hao K, Murphy B, Reindl-Schwaighofer R, Heinzl A, Oberbauer R, Viklicky O, Conlon PJ, Stapleton CP, Bakker SJL, Snieder H, Peters EDJ, van der Zwaag B, Knoers NVAM, de Borst MH, van Eerde AM.

J Am Soc Nephrol. 2018 Jun;29(6):1772-1779. doi: 10.1681/ASN.2017111200. Epub 2018 Apr 13.


Examining Whether The Health-In-All-Policies Approach Promotes Health Equity.

Hall RL, Jacobson PD.

Health Aff (Millwood). 2018 Mar;37(3):364-370. doi: 10.1377/hlthaff.2017.1292.


Risk of suicide and non-fatal self-harm after bariatric surgery: results from two matched cohort studies.

Neovius M, Bruze G, Jacobson P, Sjöholm K, Johansson K, Granath F, Sundström J, Näslund I, Marcus C, Ottosson J, Peltonen M, Carlsson LMS.

Lancet Diabetes Endocrinol. 2018 Mar;6(3):197-207. doi: 10.1016/S2213-8587(17)30437-0. Epub 2018 Jan 9.


Mycophenolic Acid and Its Metabolites in Kidney Transplant Recipients: A Semimechanistic Enterohepatic Circulation Model to Improve Estimating Exposure.

Okour M, Jacobson PA, Ahmed MA, Israni AK, Brundage RC.

J Clin Pharmacol. 2018 May;58(5):628-639. doi: 10.1002/jcph.1064. Epub 2018 Jan 12.


Attempted validation of 44 reported SNPs associated with tacrolimus troughs in a cohort of kidney allograft recipients.

Oetting WS, Wu B, Schladt DP, Guan W, Remmel RP, Dorr C, Mannon RB, Matas AJ, Israni AK, Jacobson PA.

Pharmacogenomics. 2018 Feb;19(3):175-184. doi: 10.2217/pgs-2017-0187. Epub 2018 Jan 10.


Identifying risk for language impairment in children from linguistically diverse low-income schools.

Jacobson PF, Thompson Miller S.

Int J Speech Lang Pathol. 2017 Dec 7:1-10. doi: 10.1080/17549507.2017.1406987. [Epub ahead of print]


Genome-wide association study identifies the common variants in CYP3A4 and CYP3A5 responsible for variation in tacrolimus trough concentration in Caucasian kidney transplant recipients.

Oetting WS, Wu B, Schladt DP, Guan W, Remmel RP, Mannon RB, Matas AJ, Israni AK, Jacobson PA.

Pharmacogenomics J. 2018 May 22;18(3):501-505. doi: 10.1038/tpj.2017.49. Epub 2017 Nov 21.


Discordance between age- and size-based criteria of child passenger restraint appropriateness.

Smiley ML, Bingham CR, Jacobson PD, Macy ML.

Traffic Inj Prev. 2018 Apr 3;19(3):326-331. doi: 10.1080/15389588.2017.1403016. Epub 2018 Feb 23.


Concepts of Genomics in Kidney Transplantation.

Oetting WS, Dorr C, Remmel RP, Matas AJ, Israni AK, Jacobson PA.

Curr Transplant Rep. 2017 Jun;4(2):116-123. doi: 10.1007/s40472-017-0153-x. Epub 2017 May 24.


Genetics of acute rejection after kidney transplantation.

Dorr CR, Oetting WS, Jacobson PA, Israni AK.

Transpl Int. 2018 Mar;31(3):263-277. doi: 10.1111/tri.13084. Epub 2017 Nov 8. Review.


Comparative analyses of industrial-scale human platelet lysate preparations.

Pierce J, Benedetti E, Preslar A, Jacobson P, Jin P, Stroncek DF, Reems JA.

Transfusion. 2017 Dec;57(12):2858-2869. doi: 10.1111/trf.14324. Epub 2017 Oct 8.


Influence of Kidney Transplant Status on Warfarin Dose, Anticoagulation Control, and Risk of Hemorrhage.

Yanik MV, Irvin MR, Beasley TM, Jacobson PA, Julian BA, Limdi NA.

Pharmacotherapy. 2017 Nov;37(11):1366-1373. doi: 10.1002/phar.2032. Epub 2017 Nov 2.


Disentangling the effects of a century of eutrophication and climate warming on freshwater lake fish assemblages.

Jacobson PC, Hansen GJA, Bethke BJ, Cross TK.

PLoS One. 2017 Aug 4;12(8):e0182667. doi: 10.1371/journal.pone.0182667. eCollection 2017.


Iodine Status After Bariatric Surgery-a Prospective 10-Year Report from the Swedish Obese Subjects (SOS) Study.

Manousou S, Carlsson LMS, Eggertsen R, Hulthén L, Jacobson P, Landin-Wilhelmsen K, Trimpou P, Svensson PA, Nyström HF.

Obes Surg. 2018 Feb;28(2):349-357. doi: 10.1007/s11695-017-2833-0.


A cross-scale trophic cascade from large predatory fish to algae in coastal ecosystems.

Donadi S, Austin ÅN, Bergström U, Eriksson BK, Hansen JP, Jacobson P, Sundblad G, van Regteren M, Eklöf JS.

Proc Biol Sci. 2017 Jul 26;284(1859). pii: 20170045. doi: 10.1098/rspb.2017.0045.


Collaborating for Health: Health in All Policies and the Law.

Pepin D, Winig BD, Carr D, Jacobson PD.

J Law Med Ethics. 2017 Mar;45(1_suppl):60-64. doi: 10.1177/1073110517703327.


CRISPR/Cas9 Genetic Modification of CYP3A5 *3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism.

Dorr CR, Remmel RP, Muthusamy A, Fisher J, Moriarity BS, Yasuda K, Wu B, Guan W, Schuetz EG, Oetting WS, Jacobson PA, Israni AK.

Drug Metab Dispos. 2017 Aug;45(8):957-965. doi: 10.1124/dmd.117.076307. Epub 2017 May 22.


Potential energy-driven spin manipulation via a controllable hydrogen ligand.

Jacobson P, Muenks M, Laskin G, Brovko O, Stepanyuk V, Ternes M, Kern K.

Sci Adv. 2017 Apr 14;3(4):e1602060. doi: 10.1126/sciadv.1602060. eCollection 2017 Apr.


Oxidant-induced autophagy and ferritin degradation contribute to epithelial-mesenchymal transition through lysosomal iron.

Sioutas A, Vainikka LK, Kentson M, Dam-Larsen S, Wennerström U, Jacobson P, Persson HL.

J Inflamm Res. 2017 Mar 28;10:29-39. doi: 10.2147/JIR.S128292. eCollection 2017.


Long-term incidence of female-specific cancer after bariatric surgery or usual care in the Swedish Obese Subjects Study.

Anveden Å, Taube M, Peltonen M, Jacobson P, Andersson-Assarsson JC, Sjöholm K, Svensson PA, Carlsson LMS.

Gynecol Oncol. 2017 May;145(2):224-229. doi: 10.1016/j.ygyno.2017.02.036. Epub 2017 Mar 1.


Long-term incidence of microvascular disease after bariatric surgery or usual care in patients with obesity, stratified by baseline glycaemic status: a post-hoc analysis of participants from the Swedish Obese Subjects study.

Carlsson LMS, Sjöholm K, Karlsson C, Jacobson P, Andersson-Assarsson JC, Svensson PA, Larsson I, Hjorth S, Neovius M, Taube M, Carlsson B, Peltonen M.

Lancet Diabetes Endocrinol. 2017 Apr;5(4):271-279. doi: 10.1016/S2213-8587(17)30061-X. Epub 2017 Feb 23.


Public Trust in Health Information Sharing: A Measure of System Trust.

Platt JE, Jacobson PD, Kardia SLR.

Health Serv Res. 2018 Apr;53(2):824-845. doi: 10.1111/1475-6773.12654. Epub 2017 Jan 18.


Effects of bariatric surgery on gout incidence in the Swedish Obese Subjects study: a non-randomised, prospective, controlled intervention trial.

Maglio C, Peltonen M, Neovius M, Jacobson P, Jacobsson L, Rudin A, Carlsson LM.

Ann Rheum Dis. 2017 Apr;76(4):688-693. doi: 10.1136/annrheumdis-2016-209958. Epub 2016 Oct 8.


Correlation-driven transport asymmetries through coupled spins in a tunnel junction.

Muenks M, Jacobson P, Ternes M, Kern K.

Nat Commun. 2017 Jan 11;8:14119. doi: 10.1038/ncomms14119.


Bariatric Surgery and the Risk of New-Onset Atrial Fibrillation in Swedish Obese Subjects.

Jamaly S, Carlsson L, Peltonen M, Jacobson P, Sjöström L, Karason K.

J Am Coll Cardiol. 2016 Dec 13;68(23):2497-2504. doi: 10.1016/j.jacc.2016.09.940.


The Affordable Care Act: Moving Forward in the Coming Years.

Gostin LO, Hyman DA, Jacobson PD.

JAMA. 2017 Jan 3;317(1):19-20. doi: 10.1001/jama.2016.18908. No abstract available.


Validation Is Critical for Genome-Wide Association Study-Based Associations.

Oetting WS, Jacobson PA, Israni AK.

Am J Transplant. 2017 Feb;17(2):318-319. doi: 10.1111/ajt.14051. Epub 2016 Oct 12. No abstract available.


Introduction: Perspectives on the Development of Population Health Law.

Jacobson PD, Parmet WE.

J Health Polit Policy Law. 2016 Dec;41(6):1049-1059. doi: 10.1215/03616878-3665922. Epub 2016 Aug 16. No abstract available.


Health Law 2015: Individuals and Populations.

Jacobson PD, Dahlen R.

J Health Polit Policy Law. 2016 Dec;41(6):1097-1118. doi: 10.1215/03616878-3665940. Epub 2016 Aug 16.


Sirolimus and Mycophenolate Mofetil as Calcineurin Inhibitor-Free Graft-versus-Host Disease Prophylaxis for Reduced-Intensity Conditioning Umbilical Cord Blood Transplantation.

Bejanyan N, Rogosheske J, DeFor TE, Lazaryan A, Arora M, Holtan SG, Jacobson PA, MacMillan ML, Verneris MR, Blazar BR, Weisdorf DJ, Wagner JE, Brunstein CG.

Biol Blood Marrow Transplant. 2016 Nov;22(11):2025-2030. doi: 10.1016/j.bbmt.2016.08.005. Epub 2016 Aug 9.


Collection and characterization of amniotic fluid from scheduled C-section deliveries.

Pierce J, Jacobson P, Benedetti E, Peterson E, Phibbs J, Preslar A, Reems JA.

Cell Tissue Bank. 2016 Sep;17(3):413-25. doi: 10.1007/s10561-016-9572-7. Epub 2016 Jul 26.


Pharmacokinetic-pharmacodynamic modelling of acute N-terminal pro B-type natriuretic peptide after doxorubicin infusion in breast cancer.

Liang S, Brundage RC, Jacobson PA, Blaes A, Kirstein MN.

Br J Clin Pharmacol. 2016 Sep;82(3):773-83. doi: 10.1111/bcp.12989. Epub 2016 Jun 3.


Personalized fludarabine dosing to reduce nonrelapse mortality in hematopoietic stem-cell transplant recipients receiving reduced intensity conditioning.

Sanghavi K, Wiseman A, Kirstein MN, Cao Q, Brundage R, Jensen K, Rogosheske J, Kurtzweil A, Long-Boyle J, Wagner J, Warlick ED, Brunstein CG, Weisdorf DJ, Jacobson PA.

Transl Res. 2016 Sep;175:103-115.e4. doi: 10.1016/j.trsl.2016.03.017. Epub 2016 Mar 31.


Rifampin-sirolimus-voriconazole interaction in a hematopoietic cell transplant recipient.

Wasko JA, Westholder JS, Jacobson PA.

J Oncol Pharm Pract. 2017 Jan;23(1):75-79. doi: 10.1177/1078155215624263. Epub 2016 Jul 8.


Genotype-guided tacrolimus dosing in African-American kidney transplant recipients.

Sanghavi K, Brundage RC, Miller MB, Schladt DP, Israni AK, Guan W, Oetting WS, Mannon RB, Remmel RP, Matas AJ, Jacobson PA.

Pharmacogenomics J. 2017 Jan;17(1):61-68. doi: 10.1038/tpj.2015.87. Epub 2015 Dec 15.


Genomewide Association Study of Tacrolimus Concentrations in African American Kidney Transplant Recipients Identifies Multiple CYP3A5 Alleles.

Oetting WS, Schladt DP, Guan W, Miller MB, Remmel RP, Dorr C, Sanghavi K, Mannon RB, Herrera B, Matas AJ, Salomon DR, Kwok PY, Keating BJ, Israni AK, Jacobson PA; DeKAF Investigators.

Am J Transplant. 2016 Feb;16(2):574-82. doi: 10.1111/ajt.13495. Epub 2015 Oct 20.


Quantum engineering of spin and anisotropy in magnetic molecular junctions.

Jacobson P, Herden T, Muenks M, Laskin G, Brovko O, Stepanyuk V, Ternes M, Kern K.

Nat Commun. 2015 Oct 12;6:8536. doi: 10.1038/ncomms9536.


Concept and design of a genome-wide association genotyping array tailored for transplantation-specific studies.

Li YR, van Setten J, Verma SS, Lu Y, Holmes MV, Gao H, Lek M, Nair N, Chandrupatla H, Chang B, Karczewski KJ, Wong C, Mohebnasab M, Mukhtar E, Phillips R, Tragante V, Hou C, Steel L, Lee T, Garifallou J, Guettouche T, Cao H, Guan W, Himes A, van Houten J, Pasquier A, Yu R, Carrigan E, Miller MB, Schladt D, Akdere A, Gonzalez A, Llyod KM, McGinn D, Gangasani A, Michaud Z, Colasacco A, Snyder J, Thomas K, Wang T, Wu B, Alzahrani AJ, Al-Ali AK, Al-Muhanna FA, Al-Rubaish AM, Al-Mueilo S, Monos DS, Murphy B, Olthoff KM, Wijmenga C, Webster T, Kamoun M, Balasubramanian S, Lanktree MB, Oetting WS, Garcia-Pavia P, MacArthur DG, de Bakker PI, Hakonarson H, Birdwell KA, Jacobson PA, Ritchie MD, Asselbergs FW, Israni AK, Shaked A, Keating BJ.

Genome Med. 2015 Oct 1;7:90. doi: 10.1186/s13073-015-0211-x.


Multigene predictors of tacrolimus exposure in kidney transplant recipients.

Pulk RA, Schladt DS, Oetting WS, Guan W, Israni AK, Matas AJ, Remmel RP, Jacobson PA; DeKAF Investigators.

Pharmacogenomics. 2015 Jul;16(8):841-54. doi: 10.2217/pgs.15.42. Epub 2015 Jun 12.


Assuring Quality Cancer Survivorship Care: We've Only Just Begun.

Mayer DK, Shapiro CL, Jacobson P, McCabe MS.

Am Soc Clin Oncol Educ Book. 2015:e583-91. doi: 10.14694/EdBook_AM.2015.35.e583. Review.


Non-rainfall moisture activates fungal decomposition of surface litter in the Namib Sand Sea.

Jacobson K, van Diepeningen A, Evans S, Fritts R, Gemmel P, Marsho C, Seely M, Wenndt A, Yang X, Jacobson P.

PLoS One. 2015 May 15;10(5):e0126977. doi: 10.1371/journal.pone.0126977. eCollection 2015.

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